This company has been acquired
Blueprint Medicines Past Earnings Performance
Past criteria checks 0/6
Blueprint Medicines's earnings have been declining at an average annual rate of -12.6%, while the Biotechs industry saw earnings growing at 15.2% annually. Revenues have been declining at an average rate of 3.9% per year.
Key information
-12.57%
Earnings growth rate
-11.07%
EPS growth rate
| Biotechs Industry Growth | 17.04% |
| Revenue growth rate | -3.94% |
| Return on equity | -45.52% |
| Net Margin | -27.70% |
| Last Earnings Update | 31 Mar 2025 |
Recent past performance updates
Recent updates
Sanofi Buys Blueprint: Smart Move Suits All Parties, Warrants A Rating Upgrade
Summary Sanofi's deal to acquire Blueprint was announced on June 2nd ,for an initial amount of $9.1bn, or $129 per share. Sanoi will acquire Blueprint's approved drug for mastocytosis Aykavit, which earned $150m last quarter, and could reach $2bn in revenues by 2030. There are contingent value rights that may pay up to $6 per share based on a pipeline drug, BLU-808, achieving certain milestones. Sanofi had the money and the desire to do the deal, and the price paid will likely satisfy Bluerprint shareholders - up >600% since IPO. This is, therefore, a good deal for Sanofi, and Blueprint, and could kick off a bull run on stock, as Aykavit will be immediately revenue accretive. Read the full article on Seeking Alpha
Expanding Patient Reach And Pipeline Development Will Unlock Potential
Strong AYVAKIT demand, expanded market reach, and improved therapy duration fuel revenue growth and enhance operating margin stability.Blueprint Medicines: Strong Business, Ambitious Targets, Expensive Stock
Summary Blueprint Medicines' primary revenue driver is Ayvakit, approved for various forms of Systemic Mastocytosis (SM) and showing strong growth, with 2024 revenues at $479m. The company projects Ayvakit to reach $2 billion in annual revenues by 2030, with significant growth potential as only 10% of the diagnosed SM market is penetrated. Blueprint is developing next-generation drugs like elenestinib and BLU-808, which could further enhance its SM franchise and diversify its revenue streams. Despite impressive growth and a strong cash position, I recommend a "hold" due to the stock's high valuation and the need for pipeline drugs to be further derisked. Read the full article on Seeking AlphaBlueprint Medicines: Growth For The Long Term Still Mostly Priced In
Summary Despite solid earnings beats, Blueprint Medicines is trading down ~16% since my last article. AYVAKIT/AYVAKYT revenues have doubled for four consecutive years, with 2024 guidance pegging net product revenue at $435-$450 million, a ~117% increase from 2023. CEO Haviland highlights AYVAKIT's multibillion-dollar potential, driven by its unique value proposition and strong adoption among physicians, patients, and payers. Blueprint's revised revenue guidance is based on strong first-half 2024 performance and growing experience with factors driving its business, particularly in systemic mastocytosis treatment. Read the full article on Seeking AlphaBlueprint Medicines: Overdue For A Breather
Summary Today, we take a look at Blueprint Medicines Corporation, a company focused on developing precision therapies for cancers and blood disorders. Blueprint's Q1 results were spectacular, and the company has a solid balance sheet, but the stock is up more than 150% from its lows in late October. Can the shares rally further, or are they overdue for a breather? An analysis follows in the paragraphs below. Read the full article on Seeking AlphaBlueprint Medicines: Rampant Growth Mostly Priced In
Summary Blueprint Medicines generates growing revenues from its FDA-approved product AYVAKIT/AYVAKYT. AYVAKIT has been approved for multiple indications, including gastrointestinal stromal tumor and systemic mastocytosis. Blueprint reported strong Q1 2024 earnings, achieving $92.5 million in AYVAKIT net product revenues and raising guidance for full-year revenues. Read the full article on Seeking AlphaBlueprint Medicines: Ayvakit Revenue Surge Fuels Optimism (Rating Upgrade)
Summary Blueprint Medicines' Ayvakit shows strong performance in the ISM market, with revenue projections increased to $2 billion. Q4 '23 earnings highlight significant growth, with Ayvakit driving revenues up and a strong cash position despite a high burn rate. Market sentiment is robust, supported by strong analyst projections, institutional interest, and stock momentum. I am upgrading my rating to a "strong buy," considering Ayvakit's market potential, financial health, and Blueprint's strategic positioning despite biotech investment risks. Read the full article on Seeking AlphaRevenue & Expenses Breakdown
How Blueprint Medicines makes and spends money. Based on latest reported earnings, on an LTM basis.
Earnings and Revenue History
| Date | Revenue | Earnings | G+A Expenses | R&D Expenses |
|---|---|---|---|---|
| 31 Mar 25 | 562 | -156 | 372 | 345 |
| 31 Dec 24 | 509 | -67 | 359 | 341 |
| 30 Sep 24 | 434 | -128 | 342 | 355 |
| 30 Jun 24 | 363 | -205 | 325 | 378 |
| 31 Mar 24 | 282 | -288 | 308 | 404 |
| 31 Dec 23 | 249 | -507 | 295 | 428 |
| 30 Sep 23 | 216 | -555 | 280 | 448 |
| 30 Jun 23 | 226 | -554 | 265 | 468 |
| 31 Mar 23 | 205 | -581 | 251 | 486 |
| 31 Dec 22 | 204 | -558 | 237 | 477 |
| 30 Sep 22 | 272 | -718 | 228 | 716 |
| 30 Jun 22 | 230 | -702 | 220 | 673 |
| 31 Mar 22 | 221 | -650 | 210 | 624 |
| 31 Dec 21 | 180 | -644 | 195 | 601 |
| 30 Sep 21 | 107 | -411 | 184 | 322 |
| 30 Jun 21 | 828 | 340 | 171 | 487 |
| 31 Mar 21 | 809 | 325 | 164 | 407 |
| 31 Dec 20 | 794 | 314 | 158 | 327 |
| 30 Sep 20 | 811 | 333 | 147 | 249 |
| 30 Jun 20 | 75 | -395 | 136 | 0 |
| 31 Mar 20 | 72 | -371 | 115 | 0 |
| 31 Dec 19 | 67 | -348 | 96 | 331 |
| 30 Sep 19 | 16 | -362 | 78 | 0 |
| 30 Jun 19 | 8 | -340 | 64 | 0 |
| 31 Mar 19 | 44 | -267 | 55 | 0 |
| 31 Dec 18 | 45 | -237 | 48 | 0 |
| 30 Sep 18 | 45 | -205 | 42 | 0 |
| 30 Jun 18 | 52 | -170 | 38 | 0 |
| 31 Mar 18 | 17 | -177 | 32 | 0 |
| 31 Dec 17 | 21 | -148 | 28 | 0 |
| 30 Sep 17 | 27 | -120 | 25 | 0 |
| 30 Jun 17 | 26 | -99 | 22 | 0 |
| 31 Mar 17 | 27 | -85 | 20 | 0 |
| 31 Dec 16 | 28 | -72 | 19 | 0 |
| 30 Sep 16 | 25 | -67 | 18 | 0 |
| 30 Jun 16 | 22 | -63 | 17 | 0 |
| 31 Mar 16 | 18 | -58 | 16 | 0 |
| 31 Dec 15 | 11 | -56 | 14 | 0 |
| 30 Sep 15 | 7 | -57 | 14 | 0 |
| 30 Jun 15 | 3 | -56 | 11 | 0 |
| 31 Mar 15 | 1 | -52 | 9 | 0 |
Quality Earnings: BPMC is currently unprofitable.
Growing Profit Margin: BPMC is currently unprofitable.
Free Cash Flow vs Earnings Analysis
Past Earnings Growth Analysis
Earnings Trend: BPMC is unprofitable, and losses have increased over the past 5 years at a rate of 12.6% per year.
Accelerating Growth: Unable to compare BPMC's earnings growth over the past year to its 5-year average as it is currently unprofitable
Earnings vs Industry: BPMC is unprofitable, making it difficult to compare its past year earnings growth to the Biotechs industry (21.7%).
Return on Equity
High ROE: BPMC has a negative Return on Equity (-45.52%), as it is currently unprofitable.
Return on Assets
Return on Capital Employed
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Company Analysis and Financial Data Status
| Data | Last Updated (UTC time) |
|---|---|
| Company Analysis | 2025/07/17 19:39 |
| End of Day Share Price | 2025/07/17 00:00 |
| Earnings | 2025/03/31 |
| Annual Earnings | 2024/12/31 |
Data Sources
The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.
| Package | Data | Timeframe | Example US Source * |
|---|---|---|---|
| Company Financials | 10 years |
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| Analyst Consensus Estimates | +3 years |
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| Market Prices | 30 years |
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| Ownership | 10 years |
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| Management | 10 years |
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| Key Developments | 10 years |
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* Example for US securities, for non-US equivalent regulatory forms and sources are used.
Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.
Analysis Model and Snowflake
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Industry and Sector Metrics
Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.
Analyst Sources
Blueprint Medicines Corporation is covered by 10 analysts. 19 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.
| Analyst | Institution |
|---|---|
| George Farmer | BMO Capital Markets Equity Research |
| Dane Leone | BTIG |
| Arlinda Lee | Canaccord Genuity |