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Applied Therapeutics, Inc.NasdaqCM:APLT Stock Report

Market Cap US$15.7m
Share Price
n/a
1Y-81.7%
7D7.0%
1D0.2%
Portfolio Value
View

Applied Therapeutics, Inc.

NasdaqCM:APLT Stock Report

Market Cap: US$15.7m

This company has been acquired

The company may no longer be operating, as it has been acquired. Find out why through their latest events.

Applied Therapeutics (APLT) Stock Overview

A clinical-stage biopharmaceutical company, engages in the development of a pipeline of novel product candidates against validated molecular targets in indications of high unmet medical need in the United States. More details

APLT fundamental analysis
Snowflake Score
Valuation0/6
Future Growth2/6
Past Performance0/6
Financial Health1/6
Dividends0/6

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Applied Therapeutics, Inc. Competitors

Price History & Performance

Summary of share price highs, lows and changes for Applied Therapeutics
Historical stock prices
Current Share PriceUS$0.10
52 Week HighUS$1.50
52 Week LowUS$0.09
Beta2.09
1 Month Change0.29%
3 Month Change-89.80%
1 Year Change-81.69%
3 Year Change-90.64%
5 Year Change-99.63%
Change since IPO-98.90%

Recent News & Updates

Recent updates

Analysis Article Jul 15

Here's Why Applied Therapeutics (NASDAQ:APLT) Must Use Its Cash Wisely

Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...
Analysis Article Nov 15

Here's Why We're Watching Applied Therapeutics' (NASDAQ:APLT) Cash Burn Situation

Just because a business does not make any money, does not mean that the stock will go down. By way of example, Applied...
Seeking Alpha Sep 18

Applied Therapeutics: FDA Stance Change For Advisory Panel Bodes Well For Review

Summary FDA removes the need for an advisory panel to first give a recommendation review of Applied Therapeutics, Inc.'s govorestat for the treatment of patients with galactosemia. PDUFA date of November 28th, 2024, remains on track for the FDA to decide whether govorestat should be approved to treat patients with galactosemia. Pre-NDA meeting with FDA expected in 2nd half of 2024 to discuss possible administrative actions of NDA filing submission of govorestat for the treatment of patients with SORD deficiency. If the pre-NDA meeting of govorestat for SORD deficiency goes well, then the company would be in a good position to file an NDA for this drug in Q1 of 2025. Read the full article on Seeking Alpha
Seeking Alpha Sep 04

Applied Therapeutics: Pushing Towards FDA Approval

Summary Today, we revisit clinical stage developmental concern Applied Therapeutics, Inc. for the first time in 2024. The company is moving towards its first FDA approval before yearend, and could garner another approval for a different indication in 2025. An updated analysis around Applied Therapeutics follows in the paragraphs below. Read the full article on Seeking Alpha
Analysis Article Aug 01

We're Hopeful That Applied Therapeutics (NASDAQ:APLT) Will Use Its Cash Wisely

There's no doubt that money can be made by owning shares of unprofitable businesses. By way of example, Applied...
Seeking Alpha May 28

Applied Therapeutics: Navigating Challenges In ARI Development For Rare Diseases

Summary Applied Therapeutics develops govorestat for rare diseases and AT-001 for diabetic cardiomyopathy; both are aldose reductase inhibitors. Govorestat shows promise as a treatment for galactosemia by preventing galactose conversion. AT-001’s efficacy in diabetic cardiomyopathy is inconclusive; significant results are only in certain subgroups. Hold APLT stock due to high risks despite potential in niche markets; it's suitable for a diversified high-risk portfolio segment. Read the full article on Seeking Alpha
Seeking Alpha Feb 16

Applied Therapeutics: Speedy Regulatory Review Of Govorestat Might Be Possible

Summary Positive 12-month interim results from the phase 3 INSPIRE study using govorestat for the treatment of patients with SORD deficiency achieved. Pre-NDA meeting with FDA to be sought out after to see if an NDA submission of govorestat for SORD deficiency could be done with only the positive 12-month interim data. 24-month interim results from the phase 3 INSPIRE study, using govorestat for the treatment of patients with SORD deficiency, is the next data readout to be expected. The NDA of govorestat for galactosemia has been submitted by the FDA and the EMA has validated the MAA; There is a good chance that Applied Therapeutics could receive regulatory approval for one or both of these territories. Read the full article on Seeking Alpha
Analysis Article Feb 16

Is Applied Therapeutics (NASDAQ:APLT) In A Good Position To Deliver On Growth Plans?

We can readily understand why investors are attracted to unprofitable companies. Indeed, Applied Therapeutics...
Analysis Article Nov 13

Will Applied Therapeutics (NASDAQ:APLT) Spend Its Cash Wisely?

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, Applied Therapeutics...
Analysis Article Aug 11

We're A Little Worried About Applied Therapeutics' (NASDAQ:APLT) Cash Burn Rate

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, biotech and mining...
Analysis Article May 19

We're A Little Worried About Applied Therapeutics' (NASDAQ:APLT) Cash Burn Rate

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although...
Seeking Alpha Jan 19

Applied Therapeutics: Buying This Beaten-Down, Undervalued Rare Disease Company's Stock

Applied Therapeutics shares were hammered this month after FDA did not agree to accelerated approval for its drug candidate AT-007 in treating galactosemia in children. Investors and sell-side analysts are completely discounting the potential of the pipeline. Even in a conservative scenario, shares could reach $165 by 2028 or 38x upside potential. I provide various scenarios and my calculations on revenue potential, and enterprise value potential.
Analysis Article Nov 11

Is Applied Therapeutics (NASDAQ:APLT) Using Debt In A Risky Way?

The external fund manager backed by Berkshire Hathaway's Charlie Munger, Li Lu, makes no bones about it when he says...
Analysis Article Aug 13

Here's Why We're Watching Applied Therapeutics' (NASDAQ:APLT) Cash Burn Situation

Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...
Analysis Article May 15

Will Applied Therapeutics (NASDAQ:APLT) Spend Its Cash Wisely?

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although Amazon.com...
Analysis Article Feb 26

Independent Director Stacy Kanter Just Bought 100% More Shares In Applied Therapeutics, Inc. (NASDAQ:APLT)

Investors who take an interest in Applied Therapeutics, Inc. ( NASDAQ:APLT ) should definitely note that the...

Shareholder Returns

APLTUS BiotechsUS Market
7D7.0%2.3%0.8%
1Y-81.7%42.3%20.2%

Return vs Industry: APLT underperformed the US Biotechs industry which returned 23.6% over the past year.

Return vs Market: APLT underperformed the US Market which returned 13.5% over the past year.

Price Volatility

Is APLT's price volatile compared to industry and market?
APLT volatility
APLT Average Weekly Movement28.6%
Biotechs Industry Average Movement10.3%
Market Average Movement7.3%
10% most volatile stocks in US Market16.7%
10% least volatile stocks in US Market3.2%

Stable Share Price: APLT's share price has been volatile over the past 3 months compared to the US market.

Volatility Over Time: APLT's weekly volatility (29%) has been stable over the past year, but is still higher than 75% of US stocks.

About the Company

FoundedEmployeesCEOWebsite
201628Les Funtleyderwww.appliedtherapeutics.com

Applied Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in the development of a pipeline of novel product candidates against validated molecular targets in indications of high unmet medical need in the United States. The company’s lead product candidate is AT-007 that has completed phase 3 for the treatment of galactosemia in healthy volunteers and adults, in pediatric clinical study for the treatment of galactosemia in kids, for treating enzyme sorbitol dehydrogenase, and for the treatment of phosphomannomutase enzyme-CDG. It develops AT-001 that is in phase 3 clinical trials to treat diabetic cardiomyopathy, as well as for the treatment of diabetic peripheral neuropathy; and AT-003, which is in preclinical studies for the treatment diabetic retinopathy.

Applied Therapeutics, Inc. Fundamentals Summary

How do Applied Therapeutics's earnings and revenue compare to its market cap?
APLT fundamental statistics
Market capUS$15.67m
Earnings (TTM)-US$18.14m
Revenue (TTM)US$1.00m
15.7x
P/S Ratio
-0.9x
P/E Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
APLT income statement (TTM)
RevenueUS$1.00m
Cost of RevenueUS$39.06m
Gross Profit-US$38.06m
Other Expenses-US$19.92m
Earnings-US$18.14m

Last Reported Earnings

Sep 30, 2025

Next Earnings Date

n/a

Earnings per share (EPS)-0.12
Gross Margin-3,805.60%
Net Profit Margin-1,813.80%
Debt/Equity Ratio0%

How did APLT perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/02/02 12:54
End of Day Share Price 2026/02/02 00:00
Earnings2025/09/30
Annual Earnings2024/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Applied Therapeutics, Inc. is covered by 7 analysts. 4 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Carter GouldBarclays
Paul ChoiGoldman Sachs
Luke DavisRBC Capital Markets