Alpine Immune Sciences Ownership

Who are the major shareholders and have insiders been buying or selling?

Recent Insider Transactions

NasdaqGM:ALPN Recent Insider Transactions by Companies or Individuals
Date	Value	Name	Entity	Role	Shares	Max Price
28 Dec 23	SellUS$4,217,300	OrbiMed Advisors LLC	Company		211,498	US$19.96
28 Dec 23	SellUS$24,454,434	OrbiMed Advisors LLC	Company		1,334,849	US$18.32

Insider Trading Volume

Insider Buying: Insufficient data to determine if insiders have bought more shares than they have sold in the past 3 months.

Ownership Breakdown

What is the ownership structure of ALPN?
Owner Type	Number of Shares	Ownership Percentage
Private Companies	717	0.00101%
Individual Insiders	588,847	0.83%
Hedge Funds	5,775,000	8.14%
VC/PE Firms	14,351,013	20.2%
Institutions	50,209,489	70.8%

Dilution of Shares: Shareholders have been diluted in the past year, with total shares outstanding growing by 43%.

Top Shareholders

Top 25 shareholders own 83.22% of the company

Ownership	Name	Shares	Current Value	Change %	Portfolio %
12.1%	Decheng Capital LLC	8,317,924	US$540.4m	0%	62.69%
8.79%	Frazier Life Sciences Management, LP	6,033,089	US$392.0m	92.7%	16.03%
8.42%	Avoro Capital Advisors LLC	5,775,000	US$375.2m	0%	4.58%
5.21%	BlackRock, Inc.	3,575,092	US$232.3m	16.9%	no data
4.49%	T. Rowe Price Group, Inc.	3,080,220	US$200.1m	82.6%	0.02%
4.15%	State Street Global Advisors, Inc.	2,845,839	US$184.9m	105%	0.01%
3.95%	The Vanguard Group, Inc.	2,712,285	US$176.2m	21.4%	no data
3.94%	Cormorant Asset Management, LP	2,700,000	US$175.4m	5.88%	8.58%
3.91%	OrbiMed Advisors LLC	2,680,496	US$174.2m	0%	2.37%
3.83%	Alpine BioVentures, GP, LLC	2,627,157	US$170.7m	0%	no data
3.28%	Lynx1 Capital Management LP	2,253,183	US$146.4m	-40.9%	34.0%
3.09%	Paradigm Biocapital Advisors LP	2,121,163	US$137.8m	-33.2%	5.24%
2.89%	Darwin Global Management Limited	1,982,016	US$128.8m	0%	17.66%
2%	Commodore Capital LP	1,375,000	US$89.3m	-14.6%	6.08%
1.81%	Octagon Capital Advisors LP	1,241,300	US$80.6m	0%	11.16%
1.71%	Avidity Partners Management, L.P.	1,174,700	US$76.3m	0%	2.83%
1.65%	Great Point Partners, LLC	1,128,499	US$73.3m	-67.3%	12.46%
1.59%	Franklin Resources, Inc.	1,093,203	US$71.0m	-10.4%	0.03%
1.33%	Geode Capital Management, LLC	910,599	US$59.2m	19.1%	no data
1.07%	Morgan Stanley, Investment Banking and Brokerage Investments	736,961	US$47.9m	11.7%	0.01%
0.97%	Two Sigma Advisers, LP	668,775	US$43.5m	153%	0.1%
0.76%	Vivo Capital, LLC	520,505	US$33.8m	-36.5%	2.67%
0.76%	Two Sigma Investments, LP	519,971	US$33.8m	37.4%	0.09%
0.75%	Teachers Insurance and Annuity Association-College Retirement Equities Fund	511,698	US$33.2m	297%	0.01%
0.73%	First Light Asset Management, LLC	501,243	US$32.6m	0%	2.54%