5:01 Acquisition Ownership

Who are the major shareholders and have insiders been buying or selling?

Recent Insider Transactions

Insider Buying: Insufficient data to determine if insiders have bought more shares than they have sold in the past 3 months.

Dilution of Shares: Shareholders have not been meaningfully diluted in the past year.

Top 25 shareholders own 92.06% of the company

Ownership	Name	Shares	Current Value	Change %	Portfolio %
21.7%	5AM Venture Management, LLC	2,309,194	US$23.1m	0%	5.19%
7.04%	RA Capital Management, L.P.	750,000	US$7.5m	0%	0.14%
6.71%	Saba Capital Management, L.P.	715,079	US$7.2m	0%	0.11%
6.38%	Periscope Capital Inc	680,374	US$6.8m	184%	0.27%
4.97%	Sculptor Capital Management, Inc.	529,128	US$5.3m	0%	0.08%
4.69%	Slate Path Capital LP	500,000	US$5.0m	0%	0.28%
3.92%	Mizuho Financial Group, Inc., Asset Management Arm	418,128	US$4.2m	0%	0.02%
3.91%	Citadel Advisors LLC	416,462	US$4.2m	6.25%	0.01%
3.68%	RTW Investments, LP	392,000	US$3.9m	0%	0.08%
3.22%	D. E. Shaw & Co., L.P.	343,673	US$3.4m	17.1%	0.01%
3.07%	Centiva Capital, LP	327,238	US$3.3m	20%	0.32%
3.05%	Point72 Asset Management, L.P.	324,740	US$3.2m	-19.8%	0.01%
2.65%	WR Berkley Corp., Asset Management Arm	282,843	US$2.8m	76.3%	0.15%
2.64%	RiverNorth Capital Management, LLC	281,700	US$2.8m	0%	0.13%
2.39%	RPO LLC	254,600	US$2.5m	0%	1.1%
2.28%	Millennium Management LLC	242,467	US$2.4m	-7.98%	no data
2.2%	Radcliffe Capital Management, L.P.	234,519	US$2.3m	0%	0.11%
1.88%	EcoR1 Capital, LLC	200,000	US$2.0m	0%	0.06%
1.53%	Westchester Capital Management, LLC	162,573	US$1.6m	0%	0.07%
0.8%	CSS LLC/IL, Asset Management Arm	85,601	US$856.0k	0%	0.12%
0.72%	Weiss Asset Management, LLC	76,217	US$762.2k	0.13%	0.03%
0.7%	DuPont Capital Management Corporation	75,000	US$750.0k	0%	0.04%
0.67%	Hudson River Trading LLC, Asset Management Arm	71,648	US$716.5k	-0.48%	0.01%
0.66%	CaaS Capital Management LP	70,131	US$701.3k	0%	0.09%
0.63%	Virtu Financial LLC, Asset Management Arm	66,880	US$668.8k	0%	0.06%