Prothena Ownership

Who are the major shareholders and have insiders been buying or selling?

Recent Insider Transactions

Insider Buying: Insufficient data to determine if insiders have bought more shares than they have sold in the past 3 months.

Dilution of Shares: Shareholders have not been meaningfully diluted in the past year.

Top 25 shareholders own 97.06% of the company

Ownership	Name	Shares	Current Value	Change %	Portfolio %
21.5%	EcoR1 Capital, LLC	11,584,280	US$187.8m	0%	5.91%
15%	FMR LLC	8,066,976	US$130.8m	0.02%	0.01%
10.8%	Wellington Management Group LLP	5,798,741	US$94.0m	38.8%	0.01%
7.5%	William Scully	4,036,140	US$65.4m	13.2%	no data
7.49%	BlackRock, Inc.	4,028,387	US$65.3m	4.44%	no data
7.1%	T. Rowe Price Group, Inc.	3,822,434	US$62.0m	-9.79%	0.01%
3.23%	Palo Alto Investors LP	1,737,964	US$28.2m	4.3%	3.7%
3.11%	State Street Global Advisors, Inc.	1,674,909	US$27.2m	-13.3%	no data
3.07%	Armistice Capital LLC	1,650,000	US$26.7m	5.77%	0.64%
2.34%	The Vanguard Group, Inc.	1,259,101	US$20.4m	7.46%	no data
2.04%	Artal Group S.A.	1,099,840	US$17.8m	9.83%	0.43%
1.79%	Geode Capital Management, LLC	963,479	US$15.6m	-3.1%	no data
1.59%	Dimensional Fund Advisors LP	854,050	US$13.8m	-0.87%	no data
1.28%	Tavistock Life Sciences	690,000	US$11.2m	0%	0.66%
1.16%	Rock Springs Capital Management LP	625,048	US$10.1m	0%	0.32%
1.11%	Morgan Stanley, Investment Banking and Brokerage Investments	597,726	US$9.7m	-9.42%	no data
1.1%	UBS Asset Management AG	589,254	US$9.6m	571%	no data
0.9%	Prosight Management, LP	483,467	US$7.8m	68.5%	1.94%
0.85%	Todd Fennell	458,981	US$7.4m	77.4%	no data
0.81%	Finepoint Capital LP	433,471	US$7.0m	0%	0.74%
0.75%	Federated Hermes, Inc.	404,903	US$6.6m	823%	0.02%
0.69%	Northern Trust Global Investments	372,655	US$6.0m	2.35%	no data
0.65%	Candriam, Société En Commandite Par Actions	348,187	US$5.6m	0%	0.02%
0.6%	Charles Schwab Investment Management, Inc.	324,962	US$5.3m	-0.67%	no data
0.6%	Mariner, LLC	323,213	US$5.2m	63.2%	0.01%