Ionis Pharmaceuticals, Inc.

LSE:0JDI Stock Report

Market Cap: US$5.7b

Ionis Pharmaceuticals Valuation

Is 0JDI undervalued compared to its fair value, analyst forecasts and its price relative to the market?

Valuation Score

1/6

Valuation Score 1/6

  • Below Fair Value

  • Significantly Below Fair Value

  • Price-To-Sales vs Peers

  • Price-To-Sales vs Industry

  • Price-To-Sales vs Fair Ratio

  • Analyst Forecast

Share Price vs Fair Value

What is the Fair Price of 0JDI when looking at its future cash flows? For this estimate we use a Discounted Cash Flow model.

Below Fair Value: 0JDI ($36.12) is trading above our estimate of fair value ($4.45)

Significantly Below Fair Value: 0JDI is trading above our estimate of fair value.


Key Valuation Metric

Which metric is best to use when looking at relative valuation for 0JDI?

Key metric: As 0JDI is unprofitable we use its Price-To-Sales Ratio for relative valuation analysis.

The above table shows the Price to Sales ratio for 0JDI. This is calculated by dividing 0JDI's market cap by their current revenue.
What is 0JDI's PS Ratio?
PS Ratio7.1x
SalesUS$803.07m
Market CapUS$5.67b

Price to Sales Ratio vs Peers

How does 0JDI's PS Ratio compare to its peers?

The above table shows the PS ratio for 0JDI vs its peers. Here we also display the market cap and forecasted growth for additional consideration.
CompanyForward PSEstimated GrowthMarket Cap
Peer Average5.6x
GNS Genus
1.7x3.5%UK£1.1b
OXB Oxford Biomedica
4.6x21.0%UK£447.8m
BVXP Bioventix
14.5xn/aUK£197.0m
HIK Hikma Pharmaceuticals
1.8x4.4%UK£4.3b
0JDI Ionis Pharmaceuticals
7.1x21.9%US$5.7b

Price-To-Sales vs Peers: 0JDI is expensive based on its Price-To-Sales Ratio (7.1x) compared to the peer average (5.6x).


Price to Sales Ratio vs Industry

How does 0JDI's PS Ratio compare vs other companies in the GB Biotechs Industry?

6 CompaniesPrice / SalesEstimated GrowthMarket Cap
GNS Genus
1.7x3.5%US$1.42b
OXB Oxford Biomedica
4.6x21.0%US$567.59m
TRX Tissue Regenix Group
1.6x15.1%US$51.92m
PBX ProBiotix Health
3.7xn/aUS$10.02m
0JDI 7.1xIndustry Avg. 8.0xNo. of Companies8PS020406080100+
6 CompaniesEstimated GrowthMarket Cap
No more companies

Price-To-Sales vs Industry: 0JDI is good value based on its Price-To-Sales Ratio (7.1x) compared to the European Biotechs industry average (8x).


Price to Sales Ratio vs Fair Ratio

What is 0JDI's PS Ratio compared to its Fair PS Ratio? This is the expected PS Ratio taking into account the company's forecast earnings growth, profit margins and other risk factors.

0JDI PS Ratio vs Fair Ratio.
Fair Ratio
Current PS Ratio7.1x
Fair PS Ratio4.1x

Price-To-Sales vs Fair Ratio: 0JDI is expensive based on its Price-To-Sales Ratio (7.1x) compared to the estimated Fair Price-To-Sales Ratio (4.1x).


Analyst Price Targets

What is the analyst 12-month forecast and do we have any statistical confidence in the consensus price target?

The above table shows the analyst 0JDI forecast and predictions for the stock price in 12 month’s time.
DateShare PriceAverage 1Y Price TargetDispersionHighLow1Y Actual priceAnalysts
CurrentUS$36.12
US$61.36
+69.9%
16.8%US$77.05US$37.00n/a25
Nov ’25US$38.87
US$62.31
+60.3%
16.3%US$82.00US$37.00n/a25
Oct ’25US$39.63
US$62.67
+58.1%
16.2%US$82.00US$37.00n/a25
Sep ’25US$48.24
US$62.91
+30.4%
16.0%US$82.00US$37.00n/a25
Aug ’25US$50.89
US$61.43
+20.7%
18.4%US$82.00US$33.00n/a25
Jul ’25US$46.23
US$58.51
+26.6%
18.8%US$82.00US$33.00n/a23
Jun ’25US$37.26
US$57.95
+55.5%
19.8%US$82.00US$33.00n/a23
May ’25US$41.99
US$58.13
+38.4%
20.5%US$85.00US$29.00n/a24
Apr ’25US$43.60
US$56.72
+30.1%
24.2%US$85.00US$29.00n/a22
Mar ’25US$45.90
US$56.40
+22.9%
23.8%US$85.00US$29.00n/a22
Feb ’25US$50.83
US$56.22
+10.6%
23.9%US$85.00US$28.00n/a22
Jan ’25US$50.03
US$54.87
+9.7%
24.8%US$85.00US$28.00n/a22
Dec ’24US$50.90
US$54.38
+6.8%
25.6%US$85.00US$28.00n/a22
Nov ’24US$44.97
US$53.26
+18.4%
28.9%US$88.00US$25.00US$38.8722
Oct ’24US$45.51
US$52.10
+14.5%
31.0%US$88.00US$25.00US$39.6322
Sep ’24US$40.62
US$50.96
+25.5%
33.0%US$88.00US$25.00US$48.2421
Aug ’24US$41.10
US$51.20
+24.6%
32.5%US$88.00US$24.00US$50.8921
Jul ’24US$41.06
US$50.01
+21.8%
33.5%US$88.00US$26.00US$46.2321
Jun ’24US$42.61
US$49.58
+16.4%
33.6%US$88.00US$26.00US$37.2621
May ’24US$35.25
US$48.73
+38.2%
36.6%US$92.00US$24.00US$41.9920
Apr ’24US$35.07
US$48.51
+38.3%
36.8%US$92.00US$24.00US$43.6020
Mar ’24US$35.94
US$50.01
+39.1%
35.2%US$92.00US$24.00US$45.9020
Feb ’24US$39.50
US$51.10
+29.4%
33.9%US$92.00US$24.00US$50.8320
Jan ’24US$36.75
US$51.09
+39.0%
33.6%US$92.00US$24.00US$50.0321
Dec ’23US$40.70
US$51.85
+27.4%
32.8%US$92.00US$24.00US$50.9021
Nov ’23US$45.09
US$51.14
+13.4%
34.4%US$92.00US$22.00US$44.9721

Analyst Forecast: Target price is more than 20% higher than the current share price, but analysts are not within a statistically confident range of agreement.


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