company background image
4DN logo

Denali Therapeutics DB:4DN Stock Report

Last Price

€20.48

Market Cap

€3.0b

7D

4.4%

1Y

18.8%

Updated

09 Jan, 2025

Data

Company Financials +

4DN Stock Overview

A biopharmaceutical company, develops a portfolio of product candidates engineered to cross the blood-brain barrier for neurodegenerative diseases and lysosomal storage diseases in the United States. More details

4DN fundamental analysis
Snowflake Score
Valuation3/6
Future Growth2/6
Past Performance0/6
Financial Health6/6
Dividends0/6

My Notes

Capture your thoughts, links and company narrative

Denali Therapeutics Inc. Competitors

Price History & Performance

Summary of share price highs, lows and changes for Denali Therapeutics
Historical stock prices
Current Share PriceUS$20.48
52 Week HighUS$29.67
52 Week LowUS$13.94
Beta1.39
1 Month Change-12.70%
3 Month Change-10.84%
1 Year Change18.79%
3 Year Change-30.46%
5 Year Change11.30%
Change since IPO39.60%

Recent News & Updates

Recent updates

Shareholder Returns

4DNDE BiotechsDE Market
7D4.4%6.0%1.7%
1Y18.8%-5.6%9.4%

Return vs Industry: 4DN exceeded the German Biotechs industry which returned -5.6% over the past year.

Return vs Market: 4DN exceeded the German Market which returned 9.4% over the past year.

Price Volatility

Is 4DN's price volatile compared to industry and market?
4DN volatility
4DN Average Weekly Movement9.8%
Biotechs Industry Average Movement7.4%
Market Average Movement4.9%
10% most volatile stocks in DE Market11.5%
10% least volatile stocks in DE Market2.4%

Stable Share Price: 4DN's share price has been volatile over the past 3 months compared to the German market.

Volatility Over Time: 4DN's weekly volatility (10%) has been stable over the past year, but is still higher than 75% of German stocks.

About the Company

FoundedEmployeesCEOWebsite
2013390Ryan Wattswww.denalitherapeutics.com

Denali Therapeutics Inc., a biopharmaceutical company, develops a portfolio of product candidates engineered to cross the blood-brain barrier for neurodegenerative diseases and lysosomal storage diseases in the United States. The company’s transport vehicle (TV)-enabled programs include DNL310 ETV, an IDS enzyme replacement therapy program for MPS II; TAK-594/DNL593 which is in Phase 1/II for frontotemporal dementia-granulin; DNL126 program for MPS IIIA; and DNL622 for MPS I, as well as other preclinical programs that target amyloid beta and HER2. Its brain-penetrant small molecule programs comprise BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; SAR443820/DNL788 RIPK1 inhibitor program for CNS disease; DNL343 eIF2B Activator program for amyotrophic lateral sclerosis; and SAR443122/DNL758 RIPK1 inhibitor program for peripheral inflammatory diseases.

Denali Therapeutics Inc. Fundamentals Summary

How do Denali Therapeutics's earnings and revenue compare to its market cap?
4DN fundamental statistics
Market cap€2.97b
Earnings (TTM)-€414.97m
Revenue (TTM)n/a

0.0x

P/S Ratio

-7.2x

P/E Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
4DN income statement (TTM)
RevenueUS$0
Cost of RevenueUS$412.36m
Gross Profit-US$412.36m
Other ExpensesUS$15.14m
Earnings-US$427.49m

Last Reported Earnings

Sep 30, 2024

Next Earnings Date

n/a

Earnings per share (EPS)-2.97
Gross Margin0.00%
Net Profit Margin0.00%
Debt/Equity Ratio0%

How did 4DN perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2025/01/09 01:23
End of Day Share Price 2025/01/09 00:00
Earnings2024/09/30
Annual Earnings2023/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more here.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on .

Analyst Sources

Denali Therapeutics Inc. is covered by 23 analysts. 16 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Joel BeattyBaird
Caroline PalomequeBerenberg
Tazeen AhmadBofA Global Research