Prothena Corporation plc

DB:0PT Stock Report

Market Cap: €346.5m

Prothena Valuation

Is 0PT undervalued compared to its fair value, analyst forecasts and its price relative to the market?

Valuation Score

4/6

Valuation Score 4/6

  • Below Fair Value

  • Significantly Below Fair Value

  • Price-To-Sales vs Peers

  • Price-To-Sales vs Industry

  • Price-To-Sales vs Fair Ratio

  • Analyst Forecast

Share Price vs Fair Value

What is the Fair Price of 0PT when looking at its future cash flows? For this estimate we use a Discounted Cash Flow model.

Discounted Cash Flow
Simply Wall St
€31.38
Fair Value
80.1% undervalued intrinsic discount
8
Number of Analysts

Below Fair Value: 0PT (€6.25) is trading below our estimate of fair value (€31.38)

Significantly Below Fair Value: 0PT is trading below fair value by more than 20%.

Key Valuation Metric

Which metric is best to use when looking at relative valuation for 0PT?

Key metric: As 0PT is unprofitable we use its Price-To-Sales Ratio for relative valuation analysis.

The above table shows the Price to Sales ratio for 0PT. This is calculated by dividing 0PT's market cap by their current revenue.
What is 0PT's PS Ratio?
PS Ratio2.7x
SalesUS$137.94m
Market CapUS$392.40m

Price to Sales Ratio vs Peers

How does 0PT's PS Ratio compare to its peers?

The above table shows the PS ratio for 0PT vs its peers. Here we also display the market cap and forecasted growth for additional consideration.
CompanyForward PSEstimated GrowthMarket Cap
Peer Average8.1x
FYB Formycon
5.8x18.84%€402.6m
BIO3 Biotest
1.9xn/a€1.4b
HPHA Heidelberg Pharma
22.2x39.66%€152.4m
2INV 2invest
2.7xn/a€70.0m
0PT Prothena
2.7x43.72%€392.4m

Price-To-Sales vs Peers: 0PT is good value based on its Price-To-Sales Ratio (2.7x) compared to the peer average (8.1x).

Price to Sales Ratio vs Industry

How does 0PT's PS Ratio compare vs other companies in the DE Biotechs Industry?

11 CompaniesPrice / SalesEstimated GrowthMarket Cap
Industry Avg.7.3x15.6%
0PT Prothena
 2.7x43.72%US$392.40m
BIO3 Biotest
1.9xn/aUS$1.63b
2INV 2invest
2.7xn/aUS$79.31m
0PT 2.7xIndustry Avg. 7.3xNo. of Companies10PS01224364860+
11 CompaniesEstimated GrowthMarket Cap
Industry Avg.7.3x21.0%
0PT Prothena
 2.7x36.50%US$392.40m
No more companies

Price-To-Sales vs Industry: 0PT is good value based on its Price-To-Sales Ratio (2.7x) compared to the European Biotechs industry average (7.3x).

Price to Sales Ratio vs Fair Ratio

What is 0PT's PS Ratio compared to its Fair PS Ratio? This is the expected PS Ratio taking into account the company's forecast earnings growth, profit margins and other risk factors.

0PT PS Ratio vs Fair Ratio.
Fair Ratio
Current PS Ratio2.7x
Fair PS Ratio1.1x

Price-To-Sales vs Fair Ratio: 0PT is expensive based on its Price-To-Sales Ratio (2.7x) compared to the estimated Fair Price-To-Sales Ratio (1.1x).

Analyst Price Targets

What is the analyst 12-month forecast and do we have any statistical confidence in the consensus price target?

The above table shows the analyst 0PT forecast and predictions for the stock price in 12 month’s time.
DateShare PriceAverage 1Y Price TargetDispersionHighLow1Y Actual priceAnalysts
Current€6.25
€44.18
+606.85%
61.02%€99.18€16.23n/a8
May ’26€7.95
€45.42
+471.27%
56.05%€96.54€17.55n/a8
Apr ’26€10.80
€47.97
+344.14%
56.05%€101.96€18.54n/a8
Mar ’26€15.00
€49.35
+228.99%
56.05%€104.90€19.07n/a8
Feb ’26€13.50
€48.70
+260.71%
49.17%€92.01€21.53n/a8
Jan ’26€14.30
€47.68
+233.43%
49.17%€90.09€21.08n/a8
Dec ’25€14.90
€57.06
+282.93%
43.40%€88.75€22.66n/a7
Nov ’25€15.20
€56.53
+271.89%
41.43%€86.90€22.19n/a7
Oct ’25€15.00
€50.18
+234.54%
43.48%€84.42€21.55n/a8
Sep ’25€20.00
€56.74
+183.69%
37.69%€85.33€21.79n/a8
Aug ’25€20.60
€59.62
+189.39%
36.09%€86.55€25.78n/a8
Jul ’25€19.00
€59.62
+213.76%
36.09%€86.55€25.78n/a8
Jun ’25€18.40
€59.62
+224.00%
36.09%€86.55€25.78n/a8
May ’25€19.20
€60.99
+217.65%
32.32%€86.74€31.38€7.9510
Apr ’25€22.80
€60.15
+163.82%
31.04%€86.04€31.12€10.8011
Mar ’25€26.20
€61.13
+133.30%
30.05%€86.95€32.38€15.0011
Feb ’25€25.20
€67.55
+168.06%
29.71%€92.23€33.20€13.5012
Jan ’25€34.60
€75.86
+119.25%
30.89%€119.84€39.95€14.3012
Dec ’24€29.60
€77.97
+163.42%
30.69%€120.54€40.18€14.9011
Nov ’24€34.60
€83.25
+140.61%
26.24%€122.19€50.11€15.2010
Oct ’24€45.60
€85.26
+86.97%
21.12%€117.70€54.74€15.009
Sep ’24€51.00
€85.26
+67.17%
21.12%€117.70€54.74€20.009
Aug ’24€62.00
€84.13
+35.69%
21.21%€116.28€54.08€20.609
Jul ’24€62.00
€85.21
+37.43%
20.22%€118.19€54.97€19.0010
Jun ’24€61.00
€83.71
+37.23%
18.68%€109.07€54.53€18.4010
May ’24€47.80
€77.51
+62.16%
19.98%€108.66€49.80€19.2010
AnalystConsensusTarget
Consensus Narrative from 8 Analysts
€44.90
Fair Value
86.1% undervalued intrinsic discount
8
Number of Analysts

Analyst Forecast: Target price is more than 20% higher than the current share price, but analysts are not within a statistically confident range of agreement.

Discover undervalued companies

7D

1Y

7D

1Y

7D

1Y

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2025/05/21 04:38
End of Day Share Price 2025/05/21 00:00
Earnings2025/03/31
Annual Earnings2024/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Prothena Corporation plc is covered by 24 analysts. 9 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Geoffrey MeachamBarclays
Tazeen AhmadBofA Global Research
null nullBTIG