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Rhythm Pharmaceuticals, Inc. Stock Price

NasdaqGM:RYTM Community·US$6.0b Market Cap
  • 1 Narratives written by author
  • 0 Comments on narratives written by author
  • 10 Fair Values set on narratives written by author

RYTM Share Price Performance

US$88.38
25.48 (40.51%)
US$138.20
Fair Value
US$88.38
25.48 (40.51%)
36.0% undervalued intrinsic discount
US$138.20
Fair Value
Price US$88.38
AnalystConsensusTarget US$138.20

RYTM Community Narratives

·
Fair Value US$138.2 36.0% undervalued intrinsic discount

Analysts Boost Rhythm Pharmaceuticals Outlook Amid Setmelanotide Progress and Revised Valuation Metrics

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Trending Discussion

Updated Narratives

RYTM logo

RYTM: Hypothalamic Obesity Approval Will Drive Next Phase Of Upside

Fair Value: US$138.2 36.0% undervalued intrinsic discount
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Snowflake Analysis

High growth potential with adequate balance sheet.

0 Risks
3 Rewards

Rhythm Pharmaceuticals, Inc. Key Details

US$217.2m

Revenue

US$23.0m

Cost of Revenue

US$194.2m

Gross Profit

US$402.0m

Other Expenses

-US$207.8m

Earnings

Last Reported Earnings
Mar 31, 2026
Next Reporting Earnings
n/a
-3.03
89.41%
-95.71%
45.6%
View Full Analysis

About RYTM

Founded
2008
Employees
414
CEO
David Meeker
WebsiteView website
rhythmtx.com

Rhythm Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the rare neuroendocrine diseases in the United States and internationally. The company’s lead product candidate is IMCIVREE (setmelanotide), a rare melanocortin-4 receptor for the treatment of pro-opiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1, leptin receptor (LEPR) deficiency obesity, Bardet-Biedl and Alström syndrome, Prader-Willi syndrome, and hypothalamic obesity. It is in Phase 3 clinical trials for treating acquired hypothalamic obesity, congenital hypothalamic obesity, pro-opiomelanocortin (POMC) and LEPR insufficiency obesities, SRC1 deficiency obesity, and SH2B1 deficiency obesity; and in phase 2 clinical trails for the treatment of Prader-Willi syndrome and MC4R deficiency. The company is also developing bivamelagon, an investigational oral small molecule MC4R agonist that is in phase 2 clinical trial for the treatment of MC4R pathway diseases; and RM-718, a next generation MC4R peptide agonist that is in phase 1 clinical trial for the treatment of hypothalamic obesity. The company was formerly known as Rhythm Metabolic, Inc. and changed its name to Rhythm Pharmaceuticals, Inc. in October 2015. Rhythm Pharmaceuticals, Inc. was founded in 2008 and is headquartered in Boston, Massachusetts.

Recent RYTM News & Updates

Narrative Update Jun 03

RYTM: Hypothalamic Obesity Approval Will Drive Next Phase Of Upside

Narrative Update The updated analyst price target framework for Rhythm Pharmaceuticals reflects a modest fair value move to $138.20, with analysts pointing to adjusted revenue growth expectations, higher projected profit margins, and a lower future P/E assumption after recent EMANATE trial readouts and reassessments of setmelanotide opportunities. Analyst Commentary Recent research updates on Rhythm Pharmaceuticals reflect a mix of optimism around near term commercial execution and concern around the implications of the EMANATE Phase 3 miss for longer term rare obesity opportunities.
Seeking Alpha Jun 03

Rhythm Pharmaceuticals: The Rare Obesity Platform Is Becoming A Commercial Engine

Summary Rhythm Pharmaceuticals is transitioning from a development stage to a commercial rare disease leader, leveraging its IMCIVREE franchise for biologically defined obesity. IMCIVREE’s recent FDA and EU approvals for acquired hypothalamic obesity unlock a significant, underserved market with rapid early uptake and global expansion potential. RYTM’s premium valuation is justified by rapid revenue growth, multiple approved indications, global infrastructure, and a robust pipeline targeting rare neuroendocrine obesity. Key near-term catalysts include U.S. launch execution, Japanese regulatory decision, pivotal oral bivamelagon trial, and pipeline progress in congenital HO and PWS. Read the full article on Seeking Alpha

Recent updates

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