Announcement • Jun 22
Fusion Antibodies Receives Notice of Allowance for Canadian Patent Application Covering Antibody Library and Method Fusion Antibodies plc announced that the Canadian Intellectual Property Office has issued a notice of allowance in respect of the Company's Canadian patent application no. 3,115,150. The Patent Application entitled "Antibody Library and Method", covers two families of antibodies, and the method for the design of such antibody libraries. The patent, once granted, is expected to be complementary to Fusion's offering to provide "Opti" designed antibody libraries for a range of applications including: Antibody Discovery; Affinity Maturation; and Sequence Optimisation. The Company is also progressing additional patent applications in respect of the OptiMAL Library in Canada and several other territories worldwide including Europe and China. Receipt of a notice of allowance indicates that the claims in the Patent Application are patentable and does not in itself represent a grant of patent rights. Fusion anticipates that the patent will be granted upon completion of certain administrative requirements, including payment of the Patent Application, in due course. Announcement • Jun 15
Fusion Antibodies plc Receives Grant Funding from UK Research & Innovation and InvestNI Fusion Antibodies plc provided the following update on the progress of the InnovateUK Launchpad grant in collaboration with Queen's University Belfast. The primary purpose of the Grant is to develop a humanised antibody targeting and activating the DR5 protein on cancer cells for the treatment of cancers resistant to other therapies, with the aim of producing a clinic-ready therapeutic asset capable of being licensed to a third-party pharmaceutical or biotechnology company. The Grant funds are being provided by UK Research & Innovation and InvestNI. The DR5 antibody has been successfully humanised from the initial rabbit antibody using the Company's proprietary CDRx humanisation platform, and a number of more complex structural variants have been developed and assessed in parallel. All variants are producing positive results in tumour cell death assays, demonstrating the Company's expertise with advanced antibody engineering. The gene encoding the lead humanised antibody has been successfully inserted and developed into a stable cell line suitable for large-scale manufacture. This cell line development part of the process made use of new microfluidic technology housed at the Future Medicines Institute and reduced the process timeline by approximately 50% to around four months. Given the progress made to date, UK Research & Innovation has agreed to extend the project from its originally targeted completion date of October 31, 2026 to December 31, 2026. Over the remaining months of the project, the DR5 humanised antibody and selected variants will undergo further pre-clinical evaluation in relevant cancer models. Positive results are expected to support a patent application covering the antibody family and could lead to the creation of a licensable therapeutic asset for further development and commercialisation by an industry partner. Total Grant funding is over GBP 808,000 of which up to GBP 545,000 of direct non-dilutive funding available to Fusion. Eligible costs include Labour, Overheads and Materials. The project has provided valuable Case Study data for several of Fusion's key technologies including CDRx humanisation, complex protein engineering capability, more rapid cell line development, and the potential to generate a licensable asset. A formal Collaboration Agreement has been signed by Fusion and Queen's University Belfast. New Risk • Jun 12
New minor risk - Financial data availability The company's latest financial reports are more than 6 months old. Last reported fiscal period ended September 2025. This is considered a minor risk. If the company has not reported its earnings on time, it may have been delayed due to audit problems or it may be finding it difficult to reconcile its accounts. Currently, the following risks have been identified for the company: Minor Risks Latest financial reports are more than 6 months old (reported September 2025 fiscal period end). Currently unprofitable and not forecast to become profitable next year (UK£927k net loss next year). Share price has been volatile over the past 3 months (8.9% average weekly change). Revenue is less than US$5m (UK£1.6m revenue, or US$2.1m). Market cap is less than US$100m (UK£15.3m market cap, or US$20.5m). 
