Silence Therapeutics plc

NasdaqGM:SLN Voorraadrapport

Marktkapitalisatie: US$316.0m

Silence Therapeutics Beheer

Beheer criteriumcontroles 3/4

De CEO Silence Therapeutics is Iain Ross, benoemd in Dec2025, heeft een ambtstermijn van minder dan een jaar. De totale jaarlijkse vergoeding van { bedraagt $ 3.15M, bestaande uit 0.5% salaris en 99.5% bonussen, inclusief aandelen en opties van het bedrijf. bezit rechtstreeks 0.028% van de aandelen van het bedrijf, ter waarde $ 89.08K. De gemiddelde ambtstermijn van het managementteam en de raad van bestuur bedraagt respectievelijk 2.8 jaar en 6.3 jaar.

Belangrijke informatie

Iain Ross

Algemeen directeur

US$3.1m

Totale compensatie

Percentage CEO-salaris0.54%
Dienstverband CEOless than a year
Eigendom CEO0.03%
Management gemiddelde ambtstermijn2.8yrs
Gemiddelde ambtstermijn bestuur6.3yrs

Recente managementupdates

Recent updates

Seeking Alpha Jun 12

Silence: 'Buy' Zerlasiran Program Shift And Divesiran Results August 2026

Summary Silence Therapeutics plc is maintained at a Buy rating, driven by progress in its siRNA pipeline for polycythemia vera [PV] and ASCVD. Company's lead candidate, divesiran, showed sustained reduction in phlebotomies and symptom improvement in phase 1 SANRECO data, with phase 2 topline results expected August 2026. Company seeks a partner to advance zelrasiran into phase 3 for ASCVD, prioritizing collaboration over solo development to mitigate financial risk. Cash runway is limited to 12 months; SLN may raise funds via an ATM facility, with dilution risk unless a partnership materializes. Read the full article on Seeking Alpha
Narratiefupdate Jun 01

SLN: Future Offering Program Will Shape Upside Risk Reward Profile

Analysts have adjusted their price target on Silence Therapeutics to $31.20. This reflects updated assumptions around growth, profitability and a higher future P/E multiple that together indicate a different risk and reward profile than before.
Analyseartikel Feb 05

Revenues Working Against Silence Therapeutics plc's (NASDAQ:SLN) Share Price Following 27% Dive

To the annoyance of some shareholders, Silence Therapeutics plc ( NASDAQ:SLN ) shares are down a considerable 27% in...
Analyseartikel Jan 31

Here's Why We're Watching Silence Therapeutics' (NASDAQ:SLN) Cash Burn Situation

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although Amazon.com...
Analyseartikel Oct 19

Here's Why We're Watching Silence Therapeutics' (NASDAQ:SLN) Cash Burn Situation

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although Amazon.com...
Analyseartikel Sep 28

Pinning Down Silence Therapeutics plc's (NASDAQ:SLN) P/S Is Difficult Right Now

With a median price-to-sales (or "P/S") ratio of close to 9.9x in the Biotechs industry in the United States, you could...
Analyseartikel Aug 13

Newsflash: Silence Therapeutics plc (NASDAQ:SLN) Analysts Have Been Trimming Their Revenue Forecasts

NasdaqGM:SLN 1 Year Share Price vs Fair Value Explore Silence Therapeutics's Fair Values from the Community and select...
Analyseartikel Aug 12

Silence Therapeutics plc (NASDAQ:SLN) Second-Quarter Results: Here's What Analysts Are Forecasting For This Year

NasdaqGM:SLN 1 Year Share Price vs Fair Value Explore Silence Therapeutics's Fair Values from the Community and select...
Narratiefupdate Aug 08

ALPACAR-360 Success And AstraZeneca Collaboration Will Advance siRNA Pipeline

The upward revision in Silence Therapeutics’ price target reflects significantly improved consensus revenue growth forecasts and a lower future P/E multiple, resulting in an increased fair value estimate from $32.37 to $37.26. What's in the News Silence Therapeutics approved the application of Article 159 of its articles of association, effective from the recent AGM to the next annual general meeting.
Analyseartikel May 11

Silence Therapeutics plc (NASDAQ:SLN) First-Quarter Results Just Came Out: Here's What Analysts Are Forecasting For This Year

The analysts might have been a bit too bullish on Silence Therapeutics plc ( NASDAQ:SLN ), given that the company fell...
Analyseartikel May 06

Silence Therapeutics plc's (NASDAQ:SLN) Price Is Right But Growth Is Lacking After Shares Rocket 50%

Those holding Silence Therapeutics plc ( NASDAQ:SLN ) shares would be relieved that the share price has rebounded 50...
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Nieuw narratief Apr 01

ALPACAR-360 Success And AstraZeneca Collaboration Will Advance siRNA Pipeline

The company's strategic partnerships and collaborations could reduce financial risk and enhance revenue growth through shared commercialization and milestone payments.
Analyseartikel Mar 22

Silence Therapeutics plc (NASDAQ:SLN) Looks Inexpensive After Falling 29% But Perhaps Not Attractive Enough

Unfortunately for some shareholders, the Silence Therapeutics plc ( NASDAQ:SLN ) share price has dived 29% in the last...
Analyseartikel Mar 06

These Analysts Think Silence Therapeutics plc's (NASDAQ:SLN) Sales Are Under Threat

Market forces rained on the parade of Silence Therapeutics plc ( NASDAQ:SLN ) shareholders today, when the analysts...
Analyseartikel Mar 04

We're Keeping An Eye On Silence Therapeutics' (NASDAQ:SLN) Cash Burn Rate

Just because a business does not make any money, does not mean that the stock will go down. For example, although...
Analyseartikel Jan 28

Risks Still Elevated At These Prices As Silence Therapeutics plc (NASDAQ:SLN) Shares Dive 26%

Unfortunately for some shareholders, the Silence Therapeutics plc ( NASDAQ:SLN ) share price has dived 26% in the last...
Analyseartikel Dec 10

Silence Therapeutics plc (NASDAQ:SLN) May Have Run Too Fast Too Soon With Recent 54% Price Plummet

Silence Therapeutics plc ( NASDAQ:SLN ) shareholders that were waiting for something to happen have been dealt a blow...
Analyseartikel Oct 04

Some Shareholders Feeling Restless Over Silence Therapeutics plc's (NASDAQ:SLN) P/S Ratio

You may think that with a price-to-sales (or "P/S") ratio of 38.4x Silence Therapeutics plc ( NASDAQ:SLN ) is a stock...
Analyseartikel Aug 18

Silence Therapeutics plc (NASDAQ:SLN) Consensus Forecasts Have Become A Little Darker Since Its Latest Report

As you might know, Silence Therapeutics plc ( NASDAQ:SLN ) last week released its latest second-quarter, and things did...
Analyseartikel Jun 17

Silence Therapeutics plc's (NASDAQ:SLN) Shareholders Might Be Looking For Exit

You may think that with a price-to-sales (or "P/S") ratio of 26.8x Silence Therapeutics plc ( NASDAQ:SLN ) is a stock...
Analyseartikel May 21

Here's Why We're Not Too Worried About Silence Therapeutics' (NASDAQ:SLN) Cash Burn Situation

We can readily understand why investors are attracted to unprofitable companies. By way of example, Silence...
Analyseartikel Feb 07

Need To Know: Analysts Are Much More Bullish On Silence Therapeutics plc (NASDAQ:SLN) Revenues

Silence Therapeutics plc ( NASDAQ:SLN ) shareholders will have a reason to smile today, with the analysts making...
Analyseartikel Nov 27

Subdued Growth No Barrier To Silence Therapeutics plc (NASDAQ:SLN) With Shares Advancing 65%

Silence Therapeutics plc ( NASDAQ:SLN ) shares have had a really impressive month, gaining 65% after a shaky period...
Seeking Alpha Sep 08

Silence Therapeutics wins FDA’s fast track status for blood cancer therapy

U.K.-based clinical-stage biotech Silence Therapeutics plc (NASDAQ:SLN) announced Thursday that the FDA granted Fast Track Designation to SLN124 as a treatment for polycythemia vera (PV), a type of blood cancer. SLN124, belonging to a drug class called short interfering ribonucleic acid (siRNA) therapeutics, is set to undergo a Phase 1/2 study in PV this year. The FDA offers the Fast Track designation to accelerate the development and review of drugs targeted at serious conditions with unmet medical needs. It allows developers to communicate frequently with the regulator on plans for clinical studies. If certain criteria are met, such programs will also be able to win the Accelerated Approval and Priority Review, enabling them to reach patients sooner. In a clinical trial last year, SLN124 indicated proof of mechanism and was well tolerated among healthy volunteers.
Seeking Alpha Aug 12

Silence Therapeutics prices 5.95M ADSs at $9.50/share

Silence Therapeutics (NASDAQ:SLN) has priced an underwritten offering of 5.95M American Depositary Shares, each representing three ordinary shares, at a price of $9.50/ADS, for aggregate gross proceeds of ~$56.5M. All of the ADSs are being offered by Silence. Offering is expected to close on or about August 16, 2022. Silence intends to use the net proceeds of the offering, together with its existing cash and cash equivalents to fund the advancement of its clinical trials, including its Phase 2 trial of SLN360 in ASCVD and its Phase 1/2 trial of SLN124 in polycythemia vera, as well as expansion of pipeline programs, working capital and general corporate purposes.

Analyse CEO-vergoeding

Hoe is Iain Ross's beloning veranderd ten opzichte van Silence Therapeutics's winst?
DatumTotale vergoedingSalarisBedrijfswinsten
Mar 31 2026n/an/a

-US$75m

Dec 31 2025US$3mUS$17k

-US$89m

Sep 30 2025n/an/a

-US$65m

Jun 30 2025n/an/a

-US$79m

Mar 31 2025n/an/a

-US$72m

Dec 31 2024US$482kn/a

-US$45m

Sep 30 2024n/an/a

-US$73m

Jun 30 2024n/an/a

-US$50m

Mar 31 2024n/an/a

-US$44m

Dec 31 2023US$512kn/a

-US$54m

Sep 30 2023n/an/a

-US$52m

Jun 30 2023n/an/a

-US$53m

Mar 31 2023n/an/a

-US$53m

Dec 31 2022US$673kn/a

-US$50m

Sep 30 2022n/an/a

-US$40m

Jun 30 2022n/an/a

-US$47m

Mar 31 2022n/an/a

-US$51m

Dec 31 2021US$162kn/a

-US$53m

Sep 30 2021n/an/a

-US$57m

Jun 30 2021n/an/a

-US$57m

Mar 31 2021n/an/a

-US$49m

Dec 31 2020US$2mUS$386k

-US$45m

Sep 30 2020n/an/a

-US$33m

Jun 30 2020n/an/a

-US$28m

Mar 31 2020n/an/a

-US$26m

Dec 31 2019US$122kUS$121k

-US$26m

Compensatie versus markt: De totale vergoeding ($USD 3.15M ) Iain } is ongeveer het gemiddelde voor bedrijven van vergelijkbare omvang in de US markt ($USD 2.48M ).

Compensatie versus inkomsten: De vergoeding van Iain is gestegen terwijl het bedrijf verliesgevend is.


CEO

Iain Ross (72 yo)

less than a year
Tenure
US$3,145,012
Compensatie

Mr. Iain Gladstone Ross, B. Sc (Hons) Biochemistry, C. DIR, CH. D., serves as Executive Chairman at Oxford BioDynamics Plc since 2025. He has been the Non-Executive Director of Tern Plc since October 29, 2...


Leiderschapsteam

NaamPositieTenureCompensatieEigendom
Iain Ross
Interim CEO & Chairman of the Boardless than a yearUS$3.15m0.028%
$ 89.1k
Rhonda Hellums
Executive VP4.3yrsUS$1.15m0.0011%
$ 3.3k
Steven Romano
Executive VP and Chief Research & Development Officer3.2yrsUS$981.90k0.0092%
$ 29.0k
Marie Lindholm
Chief Scientific Officer2.5yrsgeen gegevensgeen gegevens
Gem Hopkins
Head of IR & Corporate Communicationsno datageen gegevensgeen gegevens
Jaimin Shah
SVP & General Counselless than a yeargeen gegevensgeen gegevens
J.P. Gabriel
Chief Technical Operations Officer3.6yrsgeen gegevensgeen gegevens
Curtis Rambaran
Chief Medical Officerno datageen gegevensgeen gegevens
2.8yrs
Gemiddelde duur
67yo
Gemiddelde leeftijd

Ervaren management: Het managementteam van SLN wordt beschouwd als ervaren (gemiddelde ambtstermijn 2.8 jaar).


Bestuursleden

NaamPositieTenureCompensatieEigendom
Iain Ross
Interim CEO & Chairman of the Board7.2yrsUS$3.15m0.028%
$ 89.1k
Rhonda Hellums
Executive VPless than a yearUS$1.15m0.0011%
$ 3.3k
Timothy McInerney
Independent Non-Executive Director1.1yrsUS$77.50kgeen gegevens
David Lemus
Independent Non-Executive Director8yrsUS$138.61k0.0053%
$ 16.8k
Gordon Duff
Chairman of Scientific Advisory Board6.3yrsgeen gegevensgeen gegevens
John Porter
Member of Scientific Advisory Board6.3yrsgeen gegevensgeen gegevens
James Ede-Golightly
Independent Non-Executive Directorless than a yearUS$236.56k0.011%
$ 33.4k
Henry Ginsberg
Member of Scientific Advisory Board6.3yrsgeen gegevensgeen gegevens
Annemieke Aartsma-Rus
Member of Scientific Advisory Board6.3yrsgeen gegevensgeen gegevens
John Whittaker
Member of Scientific Advisory Board6yrsgeen gegevensgeen gegevens
Tom Brown
Member of Scientific Advisory Board4.4yrsgeen gegevensgeen gegevens
6.3yrs
Gemiddelde duur
64yo
Gemiddelde leeftijd

Ervaren bestuur: De raad van bestuur van SLN wordt beschouwd als ervaren (gemiddelde ambtstermijn 6.3 jaar).


Bedrijfsanalyse en status van financiële gegevens

GegevensLaatst bijgewerkt (UTC-tijd)
Bedrijfsanalyse2026/06/15 16:00
Aandelenkoers aan het einde van de dag2026/06/15 00:00
Inkomsten2026/03/31
Jaarlijkse inkomsten2025/12/31

Gegevensbronnen

De gegevens die gebruikt zijn in onze bedrijfsanalyse zijn afkomstig van S&P Global Market Intelligence LLC. De volgende gegevens worden gebruikt in ons analysemodel om dit rapport te genereren. De gegevens zijn genormaliseerd, waardoor er een vertraging kan optreden voordat de bron beschikbaar is.

PakketGegevensTijdframeVoorbeeld Amerikaanse bron *
Financiële gegevens bedrijf10 jaar
  • Resultatenrekening
  • Kasstroomoverzicht
  • Balans
Consensus schattingen analisten+3 jaar
  • Financiële prognoses
  • Koersdoelen analisten
Marktprijzen30 jaar
  • Aandelenprijzen
  • Dividenden, splitsingen en acties
Eigendom10 jaar
  • Top aandeelhouders
  • Handel met voorkennis
Beheer10 jaar
  • Leiderschapsteam
  • Raad van bestuur
Belangrijkste ontwikkelingen10 jaar
  • Bedrijfsaankondigingen

* Voorbeeld voor effecten uit de VS, voor niet-Amerikaanse effecten worden gelijkwaardige formulieren en bronnen gebruikt.

Tenzij anders vermeld zijn alle financiële gegevens gebaseerd op een jaarperiode, maar worden ze elk kwartaal bijgewerkt. Dit staat bekend als Trailing Twelve Month (TTM) of Last Twelve Month (LTM) gegevens. Meer informatie.

Analysemodel en Snowflake

Details van het analysemodel dat is gebruikt om dit rapport te genereren zijn beschikbaar op onze Github-pagina. We hebben ook handleidingen over hoe je onze rapporten kunt gebruiken en tutorials op YouTube.

Leer meer over het team van wereldklasse dat het Simply Wall St-analysemodel heeft ontworpen en gebouwd.

Industrie en sector

Onze industrie- en sectormetrics worden elke 6 uur berekend door Simply Wall St, details van ons proces zijn beschikbaar op Github.

Bronnen van analisten

Silence Therapeutics plc wordt gevolgd door 13 analisten. 6 van deze analisten hebben de schattingen van de omzet of winst ingediend die zijn gebruikt als input voor ons rapport. Inzendingen van analisten worden de hele dag door bijgewerkt.

AnalistInstelling
Howard MillerCanaccord Genuity
Keay NakaeChardan Capital Markets, LLC
Nathaniel CallowayEdison Investment Research