Alnylam Pharmaceuticals, Inc.

NasdaqGS:ALNY Voorraadrapport

Marktkapitalisatie: US$40.2b

Alnylam Pharmaceuticals Toekomstige groei

Future criteriumcontroles 5/6

Alnylam Pharmaceuticals zal naar verwachting groeien in winst en omzet met respectievelijk 27.9% en 19.4% per jaar. De winst per aandeel zal naar verwachting groeien met 27.2% per jaar. Het rendement op het eigen vermogen zal over 3 jaar naar verwachting 39% zijn.

Belangrijke informatie

27.9%

Groei van de winst

27.23%

Groei van de winst per aandeel

Biotechs winstgroei25.2%
Inkomstengroei19.4%
Toekomstig rendement op eigen vermogen38.97%
Dekking van analisten

Good

Laatst bijgewerkt29 Jun 2026

Recente toekomstige groei-updates

Recent updates

Narratiefupdate Jun 30

ALNY: Cardiomyopathy Expansion And AI Partnerships Will Drive Long Term Upside

Alnylam Pharmaceuticals' analyst-derived fair value estimate has been revised from $491.92 to $434.72 as analysts temper revenue growth and margin assumptions, following mixed adjustments to price targets and updated views on the Amvuttra launch and TTR franchise trajectory. Analyst Commentary Recent commentary on Alnylam Pharmaceuticals shows a mix of optimism around the long term potential of the TTR franchise and more cautious views on execution and valuation in the near term.
Narratiefupdate Jun 16

ALNY: TTR Franchise Execution And 2030 Plan Will Support Stock Repricing

The analyst price target for Alnylam Pharmaceuticals has been adjusted to $550. This move reflects updated views on fair value, growth assumptions, and profitability, while aligning with recent Street commentary that highlights both the pullback in the stock and ongoing expectations around Amvuttra's launch and competitive pressures.
Narratiefupdate Jun 02

ALNY: Fair View Balances ATTR-CM Data Progress With Competition And Pipeline Execution

Alnylam Pharmaceuticals' analyst fair value estimate has edged down by about $1 to $310.31, as analysts balance slightly softer modeled revenue growth and a marginally higher discount rate with a stronger profit margin outlook and ongoing support from recent price target moves and coverage initiations. Analyst Commentary Street research on Alnylam Pharmaceuticals currently reflects a mix of optimism on the drug pipeline and caution on how much of that potential is already reflected in the share price.
Narratiefupdate May 11

ALNY: Fair View Weighs TTR Execution Risks Against Cardiovascular Pipeline Progress

Analysts have nudged Alnylam Pharmaceuticals' fair value estimate to $311.72 from $310.00, reflecting updated assumptions for slightly lower revenue growth and profit margins, as well as a higher future P/E multiple based on recent shifts in price targets and commentary across the Street. Analyst Commentary Recent research has highlighted a mixed backdrop for Alnylam Pharmaceuticals, with some firms revising targets higher on product execution while others voice concern that the stock already reflects optimistic outcomes.
Seeking Alpha May 01

Alnylam Pharmaceuticals: The RNAi Leader Continues To Grind Through A Quieter Year

Summary Alnylam Pharmaceuticals remains well-positioned in the TTR amyloidosis market, with a robust franchise and reliable clinical asset generation. Q1 2026 results showed 150% year-over-year TTR franchise growth despite insurance and pricing headwinds; Amvuttra continues to gain front-line share. ALNY maintains full-year TTR revenue guidance of $4.4B–$4.7B, with ongoing investments in earlier diagnosis and care coordination to expand the addressable market. Second-half updates on early-stage compounds for bleeding disorders, Huntington's, and obesity could drive more market interest. I see ALNY shares as meaningfully undervalued, supported by pipeline progress and a resilient TTR franchise, though major clinical catalysts are likely deferred. Read the full article on Seeking Alpha
Narratiefupdate Apr 20

ALNY: Fair View Balances TTR Execution Uncertainty With Cardiovascular Pipeline Progress

Analysts have trimmed the Alnylam Pharmaceuticals fair value estimate to $310 from $322.59, reflecting a series of reduced price targets and higher discount-rate assumptions, even as revenue growth expectations remain higher and long term profit margins and future P/E forecasts are more moderate. Analyst Commentary Recent Street research on Alnylam Pharmaceuticals points to a mixed setup where confidence in the RNAi platform and the Amvuttra franchise is balanced against tighter valuation views and more conservative long term assumptions.
Narratiefupdate Apr 06

ALNY: TTR Franchise Execution Will Support Confidence In 2026 Revenue Outlook

Alnylam Pharmaceuticals' analyst price targets have been reset across the Street, with several cuts from firms now clustering in a roughly $249 to $570 range, as analysts balance concerns that shares are "priced to perfection" and that long term expectations may be too rich, against continued confidence in the RNAi platform and the strong Amvuttra launch in TTR and ATTR-CM. Analyst Commentary Recent research updates show a split tape on Alnylam, with some firms trimming targets and others leaning into the story as Amvuttra execution and RNAi platform confidence remain central themes.
Narratiefupdate Mar 23

ALNY: TTR Franchise Momentum Will Support Confidence In 2026 Revenue Outlook

Alnylam Pharmaceuticals' updated analyst price targets show a wide reset across the Street, with cuts from firms now clustered around the $249 to $570 range. Analysts are balancing strong Amvuttra momentum and the RNAi platform's potential with concerns that the shares had been priced for very optimistic growth and competition assumptions.
Narratiefupdate Mar 07

ALNY: TTR Execution Will Support Confidence In 2026 Revenue Outlook

Analysts have trimmed their fair value estimate for Alnylam Pharmaceuticals by $14 to $566, reflecting higher discount rates and more conservative assumptions for revenue growth and profit margins, even as they continue to highlight strong Amvuttra traction and supportive 2026 guidance in recent research. Analyst Commentary Recent research paints a mixed picture on valuation, but there is still a clear cluster of optimistic views around Alnylam's execution, especially in its TTR franchise and Amvuttra rollout.
Narratiefupdate Feb 21

ALNY: Fair View Weighs TTR Franchise Guidance Against Launch Execution Risks

The updated analyst price target for Alnylam Pharmaceuticals has decreased by about $45 per share, as analysts refresh their models with slightly softer revenue growth assumptions, a modestly higher long-term profit margin, and a reduced future P/E multiple. Analyst Commentary Recent Street research on Alnylam Pharmaceuticals points to a mixed backdrop, with several firms revisiting their models following Q4 results, preannounced revenue figures, and updated 2026 guidance.
Narratiefupdate Feb 06

ALNY: TTR Franchise Execution Will Support Confidence In 2026 Revenue Guidance

Analysts have trimmed their average price targets on Alnylam Pharmaceuticals by roughly $35 to $70, largely reflecting updated views on Amvuttra revenue trajectories, competitive pressures in ATTR-CM and recent guidance that, while still supported by continued TTR franchise momentum, has prompted more measured growth assumptions. Analyst Commentary Recent research updates show a mixed but generally constructive tone on Alnylam, with several bullish analysts pointing to execution on the TTR franchise, early Amvuttra traction in ATTR-CM and management guidance as key supports for valuation.
Narratiefupdate Jan 23

ALNY: TTR Franchise Momentum Will Drive 2026 Revenue Guidance Confidence

Narrative Update: Alnylam Pharmaceuticals Price Target Revision The analyst price target for Alnylam Pharmaceuticals has been raised by $10 to $580, as analysts weigh mixed target changes across the Street alongside company guidance that highlights ongoing momentum in the TTR franchise and a positive outlook for revenue driven by Amvuttra. Analyst Commentary Recent Street research around Alnylam Pharmaceuticals has been active, with several price target revisions and fresh commentary following the company’s Q3 results, preliminary Q4 figures, and updated 2025 and 2026 revenue guidance.
Narratiefupdate Jan 09

ALNY: Fair View Balances TTR Guidance Upside And Launch Deceleration Risk

Alnylam Pharmaceuticals' analyst fair value estimate has been raised from about $259.89 to about $368.22, as analysts factor in stronger modeled revenue growth, higher projected profitability, and a reset to more moderate future P/E expectations following recent research updates around Amvuttra uptake and revised TTR guidance. Analyst Commentary Recent research on Alnylam highlights a mixed backdrop.
Narratiefupdate Dec 26

ALNY: Cardiomyopathy Launch Will Drive Future Upside Despite Growing Competitive Pressures

Analysts have modestly lifted their price target for Alnylam Pharmaceuticals, reflecting stronger Amvuttra driven TTR revenue expectations and a series of Street target increases into the mid 400s to mid 500s, even as they highlight a more balanced risk and the potential for range bound trading into 2026. Analyst Commentary Recent Street research reflects a constructive but increasingly balanced view on Alnylam, with multiple firms lifting price targets into the mid 400s to mid 500s on the back of stronger Amvuttra traction and higher TTR revenue expectations, while also flagging valuation and competitive considerations that could cap upside.
Narratiefupdate Dec 12

ALNY: Cardiomyopathy Launch Will Drive Future Momentum Despite Intensifying Competition

Alnylam Pharmaceuticals’ fair value estimate has nudged higher to approximately $493 from about $489 as analysts lift price targets into the mid to high $400s, citing stronger than expected Amvuttra driven TTR revenue growth and a still rich but increasingly supported long term earnings profile. Analyst Commentary Street research remains broadly constructive on Alnylam, with multiple firms lifting price targets into the mid to high $400s and several pushing above $500.
Narratiefupdate Nov 27

ALNY: Future Momentum In Cardiomyopathy Will Meet Rising Competition And Pricing Pressures

The analyst price target for Alnylam Pharmaceuticals has increased by approximately $9 to $489, as analysts cite strong Amvuttra sales, raised revenue guidance, and resilient commercial momentum as key factors supporting a more optimistic outlook. Analyst Commentary Analysts have provided a range of perspectives following Alnylam Pharmaceuticals’ recent performance, with several raising their price targets and highlighting both catalysts and areas of caution for the company’s outlook.
Narratiefupdate Nov 12

ALNY: Momentum In Cardiomyopathy Segment Will Face Intensifying Competitive Risks Ahead

Alnylam Pharmaceuticals’ fair value estimate has increased from $467.94 to $480.17. This change reflects analysts' optimism about robust Amvuttra sales, raised revenue guidance, and an improved profit margin outlook.
Narratiefupdate Oct 29

Cardiomyopathy Launches And Pipeline Expansion Will Sustain Momentum Into 2025

Analysts have increased their price target for Alnylam Pharmaceuticals by approximately $16, citing stronger than expected product launches and continued commercial momentum. Analyst Commentary Following a series of upward price target revisions, Wall Street analysts remain broadly upbeat about Alnylam Pharmaceuticals’ near-term commercial performance and long-term prospects.
Narratiefupdate Oct 14

RNAi Therapies Will Ensure Worldwide Market Expansion

Alnylam Pharmaceuticals' analyst price targets have recently moved higher, with analysts citing stronger commercial performance of Amvuttra and encouraging data from pipeline assets as drivers behind the upward revisions. The cited targets have climbed by as much as $55 to $583 per share.
Narratiefupdate Sep 23

RNAi Therapies Will Ensure Worldwide Market Expansion

Alnylam Pharmaceuticals’ price target was raised to $447.15 as analysts cited accelerating Amvuttra sales, positive clinical progress, robust financial execution, and increased revenue forecasts, reflecting growing confidence in the company’s commercial momentum and pipeline. Analyst Commentary Strong commercial momentum for Amvuttra, particularly in ATTR-CM, with sales trends and script data consistently exceeding expectations.
Narratiefupdate Sep 08

RNAi Therapies Will Ensure Worldwide Market Expansion

Alnylam’s modestly lower consensus price target to $421.20 reflects both strong near-term Amvuttra uptake in ATTR-CM and positive revenue outlook, tempered by mixed KARDIA-3 data for zilebesiran and resulting slight valuation adjustment. Analyst Commentary Bullish analysts cited strong commercial performance and encouraging uptake for Amvuttra, particularly following its approval and launch in ATTR-CM (transthyretin amyloid cardiomyopathy), as a key driver for raising price targets.
Analyseartikel Aug 01

Need To Know: Analysts Are Much More Bullish On Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY)

Alnylam Pharmaceuticals, Inc. ( NASDAQ:ALNY ) shareholders will have a reason to smile today, with the analysts making...
Seeking Alpha Mar 21

Alnylam Pharmaceuticals Ready To Go With Its Next Blockbuster

Summary Alnylam Pharmaceuticals has secured FDA approval for Amvuttra in ATTR-CM, opening the door to potential revenue of over $6B. The company's strong R&D pipeline, including promising candidates like zilebesiran, supports long-term growth and will reduce its heavy near-term reliance on the TTR franchise. Amvuttra is likely to see strong initial adoption in ATTR-CM patients who've progressed on stabilizers, but greater first-line use and switchovers could drive the upside. Alnylam's proven R&D engine and above-average success ratio make it a compelling long-term biotech investment despite arguably modest immediate upside. Read the full article on Seeking Alpha
Seeking Alpha Feb 13

Alnylam: Waiting For Regulatory Updates In March

Summary Alnylam's Amvuttra and partner Sanofi's fitusiran have PDUFA dates with the FDA next month, and approvals should create new revenue sources for the company. Alnylam's 2025 guidance for the TTR franchise implies modest growth acceleration compared to 2024, driven by Amvuttra's expected approval next month. Fitusiran's approval could result in meaningful annual royalties for Alnylam from partner Sanofi, enhancing long-term profitability and cash flows. Alnylam expects non-GAAP operating profitability in 2025. Successful regulatory approvals and strong commercial execution could push Alnylam's share price to new all-time highs within 6–12 months. Read the full article on Seeking Alpha
Seeking Alpha Oct 27

Alnylam Pharmaceuticals Q3 Earnings Preview: Key RNAi Catalysts To Watch

Summary Alnylam Pharmaceuticals is a leader in RNAi therapeutics, with multiple FDA-approved treatments and a robust pipeline targeting rare and severe conditions. The company has strong growth potential, particularly with Amvuttra for ATTR-CM, which could become a major revenue driver in a growing market. Additionally, vutrisiran for ATTR-CM could capture a significant share of a projected $11.2 billion market. Regulatory risks and competition exist, but ALNY's innovative RNAi platform and experienced team position it well for sustained success. Despite a high valuation, ALNY's positive cash flow and projected revenue growth justify a "Buy on dips" strategy for long-term investors. Read the full article on Seeking Alpha

Winst- en omzetgroeiprognoses

NasdaqGS:ALNY - Toekomstschattingen van analisten en financiële gegevens uit het verleden (USD Millions )
DatumInkomstenInkomstenVrije kasstroomGeldmiddelen uit operationele activiteitenGem. Aantal analisten
12/31/20288,6991,8962,4132,38221
12/31/20277,2911,4711,8791,84125
12/31/20265,6121,0081,3061,25326
3/31/20264,287538643715N/A
12/31/20253,714314465524N/A
9/30/20253,21083219264N/A
6/30/20252,462-280-54-18N/A
3/31/20252,348-230-77-47N/A
12/31/20242,248-278-43-8N/A
9/30/20242,095-3321657N/A
6/30/20242,344-73319372N/A
3/31/20242,003-332128189N/A
12/31/20231,828-44042104N/A
9/30/20231,724-510-672N/A
6/30/20231,237-1,064-541-473N/A
3/31/20231,143-1,065-605-537N/A
12/31/20221,037-1,131-613-541N/A
9/30/2022961-1,182-632-559N/A
6/30/2022884-981-660-578N/A
3/31/2022880-893-654-577N/A
12/31/2021844-853-718-642N/A
9/30/2021749-838-691-615N/A
6/30/2021688-887-653-591N/A
3/31/2021571-876-672-604N/A
12/31/2020493-858-685-615N/A
9/30/2020401-891-775-688N/A
6/30/2020345-846-871-760N/A
3/31/2020286-886-452-336N/A
12/31/2019220-886N/A-278N/A
9/30/2019169-821N/A-233N/A
6/30/2019101-858N/A-204N/A
3/31/201986-802N/A-595N/A
12/31/201875-761N/A-563N/A
9/30/201892-692N/A-515N/A
6/30/2018107-570N/A-460N/A
3/31/201893-525N/A-438N/A
12/31/201790-491N/A-383N/A
9/30/201769-462N/A-358N/A
6/30/201766-443N/A-335N/A
3/31/201759-414N/A-324N/A
12/31/201647-410N/A-308N/A
9/30/201637-388N/A-282N/A
6/30/201630-361N/A-261N/A
3/31/201630-342N/A-247N/A
12/31/201541-290N/A-189N/A
9/30/201558-221N/A-173N/A

Toekomstige groeivoorspellingen analisten

Verdiensten versus spaarpercentage: De verwachte winstgroei ALNY ( 27.9% per jaar) ligt boven de spaarquote ( 3.5% ).

Winst versus markt: De winst van ALNY ( 27.9% per jaar) zal naar verwachting sneller groeien dan de US markt ( 18.7% per jaar).

Hoge groeiwinsten: De winst van ALNY zal naar verwachting de komende 3 jaar aanzienlijk groeien.

Omzet versus markt: De omzet van ALNY ( 19.4% per jaar) zal naar verwachting sneller groeien dan de markt US ( 12.8% per jaar).

Hoge groei-inkomsten: De omzet van ALNY ( 19.4% per jaar) zal naar verwachting langzamer groeien dan 20% per jaar.


Groeiprognoses winst per aandeel


Toekomstig rendement op eigen vermogen

Toekomstige ROE: Het rendement op eigen vermogen ALNY zal naar verwachting over 3 jaar hoog zijn ( 39 %)


Ontdek groeibedrijven

Bedrijfsanalyse en status van financiële gegevens

GegevensLaatst bijgewerkt (UTC-tijd)
Bedrijfsanalyse2026/07/01 21:39
Aandelenkoers aan het einde van de dag2026/07/01 00:00
Inkomsten2026/03/31
Jaarlijkse inkomsten2025/12/31

Gegevensbronnen

De gegevens die gebruikt zijn in onze bedrijfsanalyse zijn afkomstig van S&P Global Market Intelligence LLC. De volgende gegevens worden gebruikt in ons analysemodel om dit rapport te genereren. De gegevens zijn genormaliseerd, waardoor er een vertraging kan optreden voordat de bron beschikbaar is.

PakketGegevensTijdframeVoorbeeld Amerikaanse bron *
Financiële gegevens bedrijf10 jaar
  • Resultatenrekening
  • Kasstroomoverzicht
  • Balans
Consensus schattingen analisten+3 jaar
  • Financiële prognoses
  • Koersdoelen analisten
Marktprijzen30 jaar
  • Aandelenprijzen
  • Dividenden, splitsingen en acties
Eigendom10 jaar
  • Top aandeelhouders
  • Handel met voorkennis
Beheer10 jaar
  • Leiderschapsteam
  • Raad van bestuur
Belangrijkste ontwikkelingen10 jaar
  • Bedrijfsaankondigingen

* Voorbeeld voor effecten uit de VS, voor niet-Amerikaanse effecten worden gelijkwaardige formulieren en bronnen gebruikt.

Tenzij anders vermeld zijn alle financiële gegevens gebaseerd op een jaarperiode, maar worden ze elk kwartaal bijgewerkt. Dit staat bekend als Trailing Twelve Month (TTM) of Last Twelve Month (LTM) gegevens. Meer informatie.

Analysemodel en Snowflake

Details van het analysemodel dat is gebruikt om dit rapport te genereren zijn beschikbaar op onze Github-pagina, we hebben ook handleidingen over hoe u onze rapporten kunt gebruiken en tutorials op YouTube.

Leer meer over het team van wereldklasse dat het Simply Wall St-analysemodel heeft ontworpen en gebouwd.

Industrie en sector

Onze industrie- en sectormetrics worden elke 6 uur berekend door Simply Wall St, details van ons proces zijn beschikbaar op Github.

Bronnen van analisten

Alnylam Pharmaceuticals, Inc. wordt gevolgd door 56 analisten. 26 van deze analisten hebben de schattingen van de omzet of winst ingediend die zijn gebruikt als input voor ons rapport. Inzendingen van analisten worden de hele dag door bijgewerkt.

AnalistInstelling
Huidong WangBarclays
Eliana MerleBarclays
Emily BodnarBerenberg