공시 • Apr 30
Veracyte Inc Presents New Data on Decipher Portfolio at AUA 2026
Veracyte, Inc. announced that more than 15 studies focused on the Decipher portfolio will be presented at the 2026 American Urological Association (AUA) Annual Meeting, taking place May 15-18 in Washington, D.C. The data showcases the growing impact of the Decipher Bladder and Prostate tests to inform more personalized patient care. The studies provide insights into molecular subtypes associated with patient outcomes in bladder cancer and feature national-scale real-world data analyses in prostate cancer that demonstrate how Decipher Prostate informs treatment decisions. Additional real-world data from the Decipher Genomics Research for Intelligent Discovery (GRID) research tool continues to fuel the flywheel of evidence in urologic cancers through ongoing research studies. At this year’s meeting, during Bladder Cancer Awareness month in May, several studies will highlight the clinical relevance of molecular subtyping in bladder cancer using the Decipher Bladder test, including its role in guiding treatment decisions and predicting outcomes. Key presentations include: Title: Molecular Characterization and a Showcase Clinical Study on Treatment De-escalation for Luminal Favorable Muscle-Invasive Bladder Cancer Presenter: Melissa Moran, DO, Rutgers Robert Wood Johnson University Hospital Format: Poster Abstract #: IP35-15 Date/Time: Saturday, May 16, 2026, 9:30 – 11:30 AM ET Location: 147A Title: Non-luminal molecular subtypes demonstrate highest complete response rates after neoadjuvant chemo-immunotherapy for Muscle-Invasive Bladder Cancer (Biomarker analyses from NURE-combo & BLASST-01 phase 2 trials) Presenter: Joep J. de Jong, M.D., Erasmus MC Cancer Institute, Rotterdam, Netherlands Format: Poster Abstract #: IP47-06 Date/Time: Saturday, May 16, 2026, 3:30 - 5:30 PM ET Location: 147A Title: Non-Luminal Subtype is Associated with Worse Overall Survival in High-Risk Non-Muscle Invasive Bladder Cancer Patients - Biomarker Results from The Bladder Cancer Prognosis Programme Presenter: Joep J. de Jong, M.D., Erasmus MC Cancer Institute, Rotterdam, Netherlands Format: Poster Abstract #: IP47-07 Date/Time: Saturday, May 16, 2026, 3:30 - 5:30 PM ET Location: 147A Title: Examining the impact of TGF-ß activity on fibroblast infiltration and immune exclusion in muscle-invasive bladder cancer Presenter: Shilpa Gupta, M.D., Cleveland Clinic Foundation Format: Podium presentation Abstract #: PD15-10 Date/Time: Saturday, May 16, 2026, 4:42 - 4:50 PM ET Location: 206 Together, these studies demonstrate how molecular subtyping can help refine risk stratification, identify patient subsets with differing clinical outcomes, and deepen understanding of tumor biology. Unlocking Insights with Real-World Evidence from Decipher Prostate and the GRID Database Large-scale analyses using Decipher genomic data alongside real-world clinical datasets provide insights into how prostate cancer management is being shaped across diverse patient populations, helping clinicians more confidently tailor treatment decisions. These efforts also support ongoing research to deepen understanding of prostate cancer biology and inform personalized care. Key presentations include: Title: Association of Biopsy-Based Genomic Classifier and Initial Treatment for Prostate Cancer: Results from a National Clinical–Genomic Linkage Presenter: Michael Leapman, M.D., Department of Urology, Yale School of Medicine Format: Poster Abstract #: IP31-20 Date/Time: Saturday, May 16, 2026, 9:30 - 11:30 AM ET Location: 145AB Title: Genomic Classifier Results and Use of Post-Prostatectomy Treatment Among a National Cohort of Patients with Prostate Cancer Presenter: Michael Leapman, M.D., Department of Urology, Yale School of Medicine Format: Poster Abstract #: IP62-22 Date/Time: Sunday, May 17, 2026, 1:00 - 3:00 PM ET Location: 146A Title: Correlative analysis of the expression of two PET imaging targets, PSMA and ACP3, in a large radical prostatectomy cohort from the Decipher GRID registry Presenter: Mohammed Shahait, M.D., UCI Urology Format: Poster Abstract #: IP62-05 Date/Time: Sunday, May 17, 2026, 1:00 - 3:00 PM ET Location: 146A More information about Veracyte’s presence at AUA 2026 can be found at the company’s booth #3405. The Decipher Prostate Genomic Classifier is a 22-gene test, developed using RNA whole-transcriptome analysis and machine learning, that helps inform treatment decisions for patients with prostate cancer. The test is performed on biopsy or surgically resected samples and provides an accurate risk of developing metastasis with standard treatment. Armed with this information, physicians can better personalize their patients’ care and may recommend less-intensive options for those at lower risk or earlier, more-intensive treatment for those at higher risk of metastasis. The Decipher Prostate test has been validated in many dozens of published studies involving more than 100,000 patients. It is the only gene expression test to achieve “Level 1B” evidence status and inclusion in the risk-stratification table in the most recent NCCN Guidelines for prostate cancer. The Decipher Bladder Genomic Classifier is a 219-gene test, developed using RNA whole-transcriptome analysis and machine learning, that is designed for use in patients following bladder cancer diagnosis who face questions regarding treatment intensity. The test classifies bladder tumors into five molecular subtypes, each having distinct tumor biology and potential clinical implications. This information can help physicians and their patients better understand the degree of benefit that would likely be gained from neoadjuvant chemotherapy and/or the likelihood of harboring non-organ-confined disease at time of surgery, respectively. The Decipher GRID database includes more than 200,000 whole-transcriptome profiles from patients with urologic cancers and is used by Veracyte and its partners to contribute to continued research and help advance understanding of prostate and other urologic cancers. GRID-derived information is available on a Research Use Only basis.