Aptose Biosciences Inc.

OTCPK:APTO.F 株式レポート

時価総額：US$4.4m

Aptose Biosciences マネジメント

マネジメント 基準チェック /34

Aptose Biosciencesの CEO はWilliam Riceで、 Oct2013年に任命され、 の在任期間は 12.58年です。 の年間総報酬は$ 1.08Mで、 62.8%給与と37.2%のボーナス（会社の株式とオプションを含む）で構成されています。 は、会社の株式の0.18%を直接所有しており、その価値は$ 7.71K 。経営陣と取締役会の平均在任期間はそれぞれ6.3年と12.6年です。

主要情報

William Rice

最高経営責任者

US$1.1m

報酬総額

CEO給与比率62.81%
CEO在任期間12.6yrs
CEOの所有権0.2%
経営陣の平均在職期間6.3yrs
取締役会の平均在任期間12.6yrs

経営陣の近況

Recent updates

Seeking Alpha • Aug 01

Aptose Biosciences Q2 2022 Earnings Preview

Aptose Biosciences (NASDAQ:APTO) is scheduled to announce Q2 earnings results on Monday, August 1st, after market close. The consensus EPS Estimate is -$0.13 and the consensus Revenue Estimate is $0M Over the last 3 months, EPS estimates have seen 6 upward revisions and 0 downward.
Seeking Alpha • Jul 19

Aptose Biosciences Continues To Drift Without Thesis-Changing Data

Aptose has made some progress in the clinic this year, including additional complete responses for lead program HM43239 and a new formulation of luxeptinib. Expansion studies of '239 in 2023 could pave the way toward registration studies, and dose escalation studies of the new luxeptinib formulation could begin in early 2023. There is a sizable market opportunity for drugs to address patients with hematological cancers who've progressed on other therapies, but the odds and timelines are long. I believe fair value for Aptose is around $4 today, but upside is tied to future positive clinical developments and there's not much room for stumbles or setbacks. It wouldn't be fair to say that there's been no clinical progress at Aptose Biosciences (APTO) since my last update, but there certainly hasn't been enough to really sway investor sentiment, particularly in light of a more risk-averse biotech market. Aptose has two credible hematological oncology products in the pipeline, but there is a still lot of de-risking needed for both programs. I do believe that the market is still heavily discounting the odds of clinical success here, but given the history of oncology drug development, and Aptose's own shaky clinical progress, that's not exactly unfair. I can still see a path toward a substantially higher fair value, but the reality is that investors are likely going to need to wait a year or more for sentiment-moving data. '239 Is Worth Further Exploration From five complete responses and one partial response back at the December 2021 ASH update, Aptose has seen two more complete responses in its HM43239 (or '239) program in relapsed or refractory AML, bringing the total to seven complete responses and one partial response among a 80mg, 120mg, and 160mg dosing group that has treated at least 41 patients as off the last cut-off (early June, ahead of the EHA meeting). Thus far the drug has shown encouraging safety/tolerability, with only one dose-limiting toxicity reported so far (muscle weakness in a patient getting a 200mg dose). While the response rates aren't eye-popping at this point, it's worth remembering that these are not the healthiest patients, as they've already seen drug progression after prior treatments. Based on the early clinical results, management is moving forward with further dose exploration at 80mg, 120mg, and 160mg (the 80mg segment has been completed, with the 120mg and 160mg cohorts about half-complete as of early June) and then two expansion studies. One expansion study will use 120mg (with 80mg and 160mg as bracketing dosages) of '293 as a single-agent therapy in FLT-3 mutated and unmutated AML, while the other will be a combination study with venetoclax (Venclexta, marketed by AbbVie (ABBV) and Roche (RHHBY)). The single-agent study should start later this year, with the combo study slated for the first half of 2023. Should the results of these studies merit it, registrational studies would then start - presumably in 2024 for the single-agent study. It's worth remembering that '293 is targeting the challenging r/r AML market. While there are solid treatment options available as front-line therapies, some patients cannot tolerate them, some do not respond, and others ultimately see their disease mutate around the treatment and become non-responsive/relapsing. Keep this in mind when comparing response rates to other drugs in the space (make sure it's an "apples to apples" comparison). Another Chance For Luxeptinib Aptose's prior lead drug, luxeptinib, still factors significantly into the company's clinical plans today. While the drug showed exciting pre-clinical attributes, clinical results today have not matched that potential. It would seem that the pharmacokinetics of the drug are at least partly to blame, and the company is hoping that a reformulated version of the drug (known as "G3") can lead to patients getting consistent therapeutic doses that produce clinical results. Clinical trial work is underway now, with patients getting G3 at 50mg, 100mg, and 200mg doses and the 50mg dose of G3 demonstrating 200x the exposure level of a 150mg dose of G1. Assuming that the pharmacokinetics and pharmacodynamics (PK and PD) studies merit further development, Aptose should be able to start dose escalation studies of the new formulation in the first half of 2023 in patients with r/r B-cell or r/r AML disease.
Seeking Alpha • Feb 02

Aptose Deep In The Doghouse Due To Lack Of Pipeline Progress

A lack of progress in the clinic, including another disappointing ASH meeting, has led investors to bail out of this risky early-stage biotech. A new formulation of luxeptinib, and potentially greater exposure to the drug, may finally unlock the potential of this once-promising drug, but it's a "show me" story. Recently-acquired '239 looks like an interesting asset for AML, with promising Phase 1 response rates, but it's still early in the development cycle. Between '239 and luxeptinib there is still potential in Aptose's pipeline, but it will take real evidence of clinical efficacy to rebuild sentiment.

CEO報酬分析

Aptose Biosciences の収益と比較して、William Rice の報酬はどのように変化したか？
日付総報酬給与会社業績
Mar 31 2026n/an/a

-US$28m

Dec 31 2025US$1mUS$677k

-US$25m

Sep 30 2025n/an/a

-US$19m

Jun 30 2025n/an/a

-US$21m

Mar 31 2025n/an/a

-US$21m

Dec 31 2024US$1mUS$647k

-US$25m

Sep 30 2024n/an/a

-US$36m

Jun 30 2024n/an/a

-US$40m

Mar 31 2024n/an/a

-US$47m

Dec 31 2023US$925kUS$623k

-US$51m

Sep 30 2023n/an/a

-US$49m

Jun 30 2023n/an/a

-US$48m

Mar 31 2023n/an/a

-US$44m

Dec 31 2022US$2mUS$599k

-US$42m

Sep 30 2022n/an/a

-US$56m

Jun 30 2022n/an/a

-US$58m

Mar 31 2022n/an/a

-US$61m

Dec 31 2021US$2mUS$582k

-US$65m

Sep 30 2021n/an/a

-US$56m

Jun 30 2021n/an/a

-US$58m

Mar 31 2021n/an/a

-US$60m

Dec 31 2020US$12mUS$582k

-US$55m

Sep 30 2020n/an/a

-US$48m

Jun 30 2020n/an/a

-US$42m

Mar 31 2020n/an/a

-US$32m

Dec 31 2019US$2mUS$562k

-US$26m

報酬と市場: Williamの 総報酬 ($USD 1.08M ) は、 US市場 ($USD 627.03K ) の同規模の企業の平均を上回っています。

報酬と収益: Williamの報酬は、過去 1 年間の会社の業績と一致しています。

CEO

William Rice (66 yo)

12.6yrs
在職期間
US$1,077,641
報酬

Dr. William G. Rice, Ph D., had served as an Independent Director of Oncolytics Biotech Inc. since June 08, 2015 until June 30, 2021. He has been the Chief Executive Officer and President of Aptose Bioscie...

リーダーシップ・チーム

名称ポジション在職期間報酬所有権
William Rice
Chairman12.6yrsUS$1.08m0.18%
$ 7.7k
Fletcher Payne
Senior VP3.9yrsUS$710.58k0.0096%
$ 420.4
Rafael Bejar
Senior VP & Chief Medical Officer6.3yrsUS$754.62k0.0096%
$ 420.4
6.3yrs
平均在職期間
62yo
平均年齢

経験豊富な経営陣: APTO.Fの経営陣は経験豊富で経験豊富です（平均在職期間は6.3年）。

取締役

名称ポジション在職期間報酬所有権
William Rice
Chairman12.6yrsUS$1.08m0.18%
$ 7.7k
Mark Vincent
Independent Director18.7yrsUS$95.00k0.00055%
$ 24.2
Bernd Seizinger
Independent Director3.7yrsUS$103.50k0.022%
$ 974.9
Denis Burger
Lead Independent Director18.7yrsUS$128.50k0.0019%
$ 82.7
Stephen Howell
Member of Scientific Advisory Boardno dataデータなしデータなし
Daniel Von Hoff
Member of Scientific Advisory Boardno dataデータなしデータなし
Erich Platzer
Independent Director11.4yrsUS$90.00k0.044%
$ 1.9k
Warren Whitehead
Independent Director15.1yrsUS$80.00k0.0013%
$ 56.7
Brian Druker
Chairman of Scientific Advisory Board12.6yrsデータなしデータなし
Michael Andreeff
Member of Scientific Advisory Board11.2yrsデータなしデータなし
12.6yrs
平均在職期間
73yo
平均年齢

経験豊富なボード: APTO.Fの 取締役会 は経験豊富で 経験豊富 です ( 12.6年の平均在任期間)。

企業分析と財務データの現状

データ最終更新日（UTC時間）
企業分析2026/05/24 21:52
終値2026/05/22 00:00
収益2026/03/31
年間収益2025/12/31

データソース

企業分析に使用したデータはS&P Global Market Intelligence LLC のものです。本レポートを作成するための分析モデルでは、以下のデータを使用しています。データは正規化されているため、ソースが利用可能になるまでに時間がかかる場合があります。

パッケージデータタイムフレーム米国ソース例
会社財務10年
  • 損益計算書
  • キャッシュ・フロー計算書
  • 貸借対照表
アナリストのコンセンサス予想+プラス3年
  • 予想財務
  • アナリストの目標株価
市場価格30年
  • 株価
  • 配当、分割、措置
所有権10年
  • トップ株主
  • インサイダー取引
マネジメント10年
  • リーダーシップ・チーム
  • 取締役会
主な進展10年
  • 会社からのお知らせ

* 米国証券を対象とした例であり、非米国証券については、同等の規制書式および情報源を使用。

特に断りのない限り、すべての財務データは1年ごとの期間に基づいていますが、四半期ごとに更新されます。これは、TTM（Trailing Twelve Month）またはLTM（Last Twelve Month）データとして知られています。詳細はこちら。

分析モデルとスノーフレーク

本レポートを生成するために使用した分析モデルの詳細は当社のGithubページでご覧いただけます。また、レポートの使用方法に関するガイドやYoutubeのチュートリアルも掲載しています。

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業界およびセクターの指標

私たちの業界とセクションの指標は、Simply Wall Stによって6時間ごとに計算されます。

アナリスト筋

Aptose Biosciences Inc. 0 これらのアナリストのうち、弊社レポートのインプットとして使用した売上高または利益の予想を提出したのは、 。アナリストの投稿は一日中更新されます。9

アナリスト機関
Matthew VeneziaAlliance Global Partners
Dylan DupuisB. Riley Securities, Inc.
John NewmanCanaccord Genuity