お知らせ • Oct 27

Vera Therapeutics, Inc. Announces 96-week eGFR Stabilization in ORIGIN Phase 2b Study of Atacicept in IgAN at the American Society of Nephrology Kidney Week 2024

Vera Therapeutics, Inc. announced data from its ORIGIN Phase 2b trial of atacicept in immunoglobulin A nephropathy (IgAN) that show stabilized kidney function through 96 weeks of long-term follow-up. These data were presented in a late-breaking oral presentation at the American Society of Nephrology Kidney Week 2024 in San Diego, California, and simultaneously published in a manuscript in the Journal of the American Society of Nephrology. Over 96 weeks, participants treated with atacicept demonstrated a -66% reduction in galactose-deficient IgA1 (Gd-IgA1), resolution of hematuria in 75% of participants, a -52% reduction in proteinuria, and a mean annualized estimated glomerular filtration rate (eGFR) slope of -0.6 mL/min/1.73m2/year. The cumulative generally favorable safety profile of atacicept remained consistent with that observed during the randomized period, with a 90% completion rate of atacicept treatment. The Company believes these data support the potential for atacicept to offer long-term, comprehensive IgAN disease modification and provide further confidence in the ongoing pivotal Phase 3 ORIGIN 3 trial of atacicept in IgAN. Upcoming milestones: ORIGIN Extend – plan to initiate a study in Fourth Quarter 2024 that will provide ORIGIN participants with extended access to atacicept prior to commercial availability in their region, as well as an opportunity to capture longer-term data. Pivotal ORIGIN 3 trial on track to announce topline results in Second Quarter 2025, with planned BLA submission to the U.S. FDA later in the year. PIONEER Study – plan to initiate a study in 2025 that will evaluate the efficacy and safety of atacicept in: Expanded IgAN populations – The first set of cohorts will include adults with low kidney function (eGFR 20 to <30 mL/min/1.73 m2), low (UPCR <1.0 g/g) or high proteinuria (UPCR =5.0 g/g) or IgAN recurrence after kidney transplant; adolescents at high risk of progression (UPCR =0.3 g/g); as well as adolescents and adults with IgA vasculitis nephritis. Anti-PLA2R and anti-nephrin podocytopathies – The PIONEER study will expand to additional autoimmune glomerular diseases characterized by the presence of antibodies to glomerular antigens, including primary membranous nephropathy, focal segmental glomerulosclerosis, and minimal change disease. Phase 2b ORIGIN clinical trial: The Phase 2b ORIGIN clinical trial (NCT04716231) is a global, multicenter, randomized, double-blind, placebo-controlled trial evaluating the safety and efficacy of atacicept in 116 patients with IgAN who continue to have persistent proteinuria and remain at high risk of disease progression despite being on a stable prescribed regimen of a renin-angiotensin-aldosterone system inhibitor for at least 12 weeks that is the maximum labeled or tolerated dose. The Phase 2b ORIGIN clinical trial evaluated three dose strengths of atacicept versus placebo, administered weekly by prefilled syringe. Patients were randomized 2:2:1:2 to atacicept 150 mg, atacicept 75 mg, atacicept 25 mg or matching placebo. Upon completion of the 36-week blinded treatment period, all patients were offered open-label atacicept 150 mg for an additional 60 weeks. The primary endpoint was the change in proteinuria as evaluated by urine protein to creatinine ratio (UPCR) at week 24, and the key secondary endpoint was the change in proteinuria as evaluated by UPCR at week 36. Additional exploratory endpoints include change in proteinuria as evaluated by UPCR at weeks 12, 48, and 96; change in eGFR; change in serum immunoglobulin levels, and change in serum Gd-IgA1 levels; safety and tolerability; and serum pharmacokinetics. The trial met its primary and key secondary endpoints, with statistically significant and clinically meaningful proteinuria reductions and stabilization of eGFR versus placebo through week 36. The safety profile was comparable between atacicept and placebo. Phase 3 ORIGIN 3 clinical trial: The ORIGIN 3 clinical trial (NCT04716231) is a global, multicenter, randomized, double-blind, placebo-controlled Phase 3 trial evaluating the safety and efficacy of atacicept in patients with IgAN who continue to have persistent proteinuria and remain at high risk of disease progression despite being on a stable prescribed regimen of renin-angiotensin system inhibitors for at least 12 weeks that is the maximum labeled or tolerated dose. The objectives of the trial are to determine the effect of atacicept on proteinuria and preservation of kidney function compared to placebo. Atacicept is an investigational recombinant fusion protein that contains the soluble transmembrane activator and calcium-modulating cyclophilin ligand interactor receptor that binds to the cytokines B-cell activating factor (BAFF) and A PRoliferation-Inducing Ligand (APRIL). These cytokines are members of the tumor necrosis factor family that promote B-cell survival and autoantibody production associated with certain autoimmune diseases, including IgAN and lupus nephritis. The Phase 2b ORIGIN clinical trial of atacicept in IgAN met its primary and key secondary endpoints, with statistically significant and clinically meaningful proteinuria reductions and stabilization of eGFR versus placebo through 36 weeks. The safety profile during the randomized period was comparable between atacicept and placebo. Through 72 weeks, atacicept demonstrated further reductions in Gd-IgA1, hematuria and proteinuria, as well as stabilization of eGFR reflecting a profile consistent with that of the general population without IgAN. Atacicept has received FDA Breakthrough Therapy Designation for the treatment of IgAN, which reflects the FDA’s determination that, based on an assessment of data from the Phase 2b ORIGIN clinical trial, atacicept may demonstrate substantial improvement on a clinically significant endpoint over available therapies for patients with IgAN. Vera believes atacicept is positioned for best-in-class potential, targeting B cells and plasma cells to reduce autoantibodies and having been administered to more than 1,500 patients in clinical studies across different indications.

Seeking Alpha • Sep 06

Vera Therapeutics: Under The Radar IgAN Player Has Much To Prove

Summary Shares have risen by 67% since May 2021 IPO. IgA Nephropathy is an increasingly attractive opportunity that multiple companies are targeting given regulatory tailwinds. Atacicept's unique value proposition is to target IgAN upstream (turn off the faucet) and strong observational data links lowering Gd-IgA1 levels to improved proteinuria. MAU868 for BK Viremia is thought to have broad potential as a prophylactic agent but I think it's a niche product at best. I cannot recommend VERA at this time and believe near-term burden of proof rests on ORIGIN phase 2b data in 2023. Shares of Vera Therapeutics (VERA) have risen by 67% since IPO priced at $11 back in May of 2021. So far in 2022, share price has fallen by almost 30%. I grew interested in this early-stage player in immunological disease space as I researched multiple Iga nephropathy (IgAN) contenders in what I consider to be an increasingly lucrative area with multiple tailwinds (see my recent article on Chinook Therapeutics which also provides a view of the overall landscape). Specifically, the FDA's willingness to accept surrogate endpoints such as proteinuria reduction for regulatory approval is speeding up development timelines and several promising drugs could improve outcomes for these patients in the next few years. Vera's dual inhibitor of BLyS and APRIL, atacicept, could have best-in-class potential for IgAN and has an important readout coming up in Q1 2023. Couple that with additional shots on goal in lupus nephritis and other indications of high unmet need, at a current enterprise value of just $400M, and it's clear why I wanted to dig deeper and see if there's a near term opportunity for my readers. Chart FinViz Figure 1: VERA weekly chart (Source: Finviz) When looking at charts, clarity often comes from taking a look at distinct time frames in order to determine important technical levels and get a feel for what's going on. In the weekly chart above, we can see shares bounce around in the $15 to $30 range for much of the past year. After bottoming in mid-teens this summer, they've again rebounded just south of $20 and appear to be consolidating for a move higher still. My initial take is that, given tailwinds to the IgAN space and presence of a near term catalyst coming up, investors interested in this story would do well to establish a pilot position and from there accumulate dips in Q3 for the potential run-up into data in 2023. Overview Founded in 2016 with headquarters in San Francisco (just 17 full-time employees), Vera Therapeutics currently sports enterprise value of ~$400M and Q2 cash position of $131M providing them operational runway for roughly 1.5 years (conservatively). At Wedbush PacGrow Healthcare Conference presentation, CEO Marshall Fordyce describes the company as developing novel medicines in the area of immune-related kidney disease where there is large unmet need and market opportunity with recent favorable regulatory conditions. Vera has 3 programs in late-stage clinical development (impressive for a small company). Corporate Slides Figure 2: Pipeline & milestones (Source: corporate presentation) Atacicept is their lead candidate, a fusion protein that is dosed once per week subcutaneously and previously has been in over a thousand patients in clinical studies (well-characterized safety and manufacturing profile). Atacicept was actually phase 3-ready when Vera licensed the drug in from Merck KGaA. Vera is developing it for two immune-driven kidney diseases, IgAN and lupus nephritis. IgAN is an autoimmune disease of the kidney affecting young people (average age of diagnosis at age 30). It's now getting attention from developers but has no disease-modifying drugs. They estimate the market to be at least in the high single digit billions in the US alone and there is emerging evidence that targeting the source of the disease (B cells which produce bad-acting auto antibodies in IgAN) could be disease-modifying and substantially improve kidney function as measured by protein in the urine and GFR. No one has shown this mechanism leads to improved kidney function in multi-national, randomized controlled studies yet and Vera hopes to be the first. Corporate Slides Figure 3: Atacicept hits two steps in the pathogenesis of IgAN (Source: corporate presentation) Atacicept targets B cell lineage through dual inhibition of APRIL and BLyS which potentially makes it more potent and confers dosing advantages versus APRIL only approach. Readout of phase 2b ORIGIN study is due in early Q1 of 2023 and will demonstrate the effect of atacicept on kidney function as measured by proteinuria as primary endpoint. These results could be very meaningful for the field. Second upcoming milestone is for lupus nephritis, as they have agreement with FDA to advance the higher dose (150mg) into a phase 3 study to be initiated this year. Third, they are developing a second molecule, MAU868, for BK virus which is a leading cause of kidney failure in transplant patients. There are no approved drugs here and they have the first results of a randomized, controlled-study showing that this neutralizing antibody can reduce BK virus in the blood versus placebo. Company has lean operating model, completely focused on clinical development and leadership team comes from Gilead and Genentech (highly experienced with drug approvals that led to blockbuster sales). Returning to IgAN, the market is quickly evolving with much more interest coming into the space. Diagnosis is done by kidney biopsy and there is reason to believe IgAN is underdiagnosed. Prior, physicians knew with diagnosis they would just give patients an angiotensin receptor blocker or ACE inhibitor if they know the patient does not have diabetes or high blood pressure driving kidney failure. Diagnosis as a kidney biopsy is still a hurdle. There are two biomarkers that track with disease severity, the bad-acting auto-antibodies (GD-IgA1) which can be assayed and IgG. Together the two may have strong specificity for diagnosis and there are efforts to bring those forward as a non-invasive approach to diagnosis. Atacicept is the first and only molecule in development to show reduction in these biomarkers in randomized, controlled trials. Hepatitis C market was a great example of how when effective therapies come along, diagnosis goes up. IgAN patients traditionally have had no treatments available except ACE inhibitors or steroids, and randomized studies for the latter have been stopped early due to known acute and chronic side effects. Tarpeyo is now approved in IgAN and it is a reformulated steroid that provides a marginal improvement. Natural history data shows that 30% reduction in proteinuria leads to improved kidney outcomes over time, and that's why Tarpeyo received accelerated approval (and potentially provides tailwind for all IgAN developers). CEO views upcoming approvals of endothelial receptor antagonists Chinook Therapeutics' (KDNY) atrasentan and Travere Therapeutics' (TVTX) sparsentan as potential improvements on ACE inhibitors or ARBs (protecting the kidney through hemodynamic change). Again, none of these approaches are disease-modifying and work downstream of this disease process. As it stands, there is strong observational data linking lowering Gd-IgA1 to improve proteinuria and leads to improved clinical outcomes including mortality and time to dialysis. However, how this translates into regulatory handling of specific programs is all conjecture at this point (too premature). Corporate Slides Figure 4: High Gd-IgA1 associated with reduced time to dialysis, transplant and death (Source: corporate presentation) For the ORIGIN phase 2b study in IgAN, they are looking for data in early 2023 (24-week assessment). Atacicept prior has been studied in a small, randomized controlled study of about 15 patients (similar population) where it showed clear reduction (60%) in Gd-IgA1 at the middle dose (75 mg). CEO considered that to be pretty compelling and they will see whether they can meet or exceed that reduction in the ORIGIN study. They did see reduction in proteinuria, but again with wide error bars because numbers were small (27.7% reduction in proteinuria at 24 weeks). ORIGIN was designed for that reason, to get a better idea of the true reduction in proteinuria they can achieve including at high dose of 150mg. Study is powered for at least a 28% reduction in proteinuria (threshold is 30%, which led to accelerated approval for Tarpeyo). Corporate Slides Figure 5: Competitor landscape in IgAN (Source: corporate presentation) They will be showing delta from placebo (prior trial had outlier that created increase in proteinuria in placebo, whereas placebo arm in ORIGIN study is expected to have no change in proteinuria at 24 weeks). 150mg dose will also be used in the lupus nephritis study. Merck was looking at taking the asset originally into systemic lupus, then they decided to focus pipeline elsewhere. Formerly, exposure safety analysis run by Merck was given a thumbs up to take 150mg dose into LN. However, dosing higher does not make sense as they do see a plateau in other disease sets (appear to be on the plateau when they go from 75mg to 150mg). Target product profile is appealing and simple, one mL subcutaneously once per week (what Humira is, for example). They are in a unique position as they know safety data in over 1000 patients. Base case is that they will have to run a phase 3 study after this phase 2b trial. ORIGIN study will be followed out to 96 weeks as long-term results are important (want to push possibility of dialysis further out into the future for these patients who are 30 years old on average at diagnosis). The hypothesis is that this drug is having a broader renal impact (removing the bad-acting auto-antibody so that downstream effects may be lessened). Mechanism will be key and again it depends on what alternatives are available (down to efficacy, safety and tolerability). They anticipate atacicept being used as a chronic, maintenance therapy (envision other mechanisms that have shorter duration, like Tarpeyo label which includes 9 months). Moving on to lupus nephritis, there were no approved drugs 2 years ago and it is a terrible disease with huge unmet need. It can have a form where it causes rash, affects joints and can also be organ-threatening (lead to stroke or kidney failure). Brain fog, fatigue and other symptoms are quite difficult to measure in a multi-national study. There are now two approved drugs in LN (voclosporin from Aurinia and Benylsta from GSK) on basis of complete renal response endpoint (lab measures of protein in urine and GFR stability). Now, there is a precedent for approvals with this endpoint and nice correlation between phase 2 and phase 3. Vera wants to see this for indications they choose for development. It looks like atacicept can be efficacious in LN, and data in subset of patients with severe disease looks promising. Primary endpoint is 52 weeks (mimics voclosporin program). BLyS only is an approved drug for LN and systemic lupus (Benlysta), and we can think of atacicept as BLyS plus X (think adding APRIL to that mechanism can perform better in a randomized, controlled study). Prior data for atacicept has shown it reduced disease-associated auto-antibodies (dose-responsive) and suggest it potentially could work. Corporate Presentation Figure 6: Phase 2 evidence of clinical efficacy in SLE (Source: corporate presentation) As for MAU868 in BK virus, I remind readers that the company acquired this asset from Amplyx Pharmaceuticals (subsidiary of Pfizer) in December of last year for a mere $5M upfront payment in addition to $7M in certain regulatory milestones and low single digit percentage royalties on net sales. Vera is also obligated to make certain milestone payments in an aggregate amount of up to $69M to Amplyx' partner Novartis as well as mid-to-high single-digit percentage royalties. At the time, Vera also entered into a credit facility with Oxford Finance of up to $50M (drew the $5M upfront payment at closing) and debt facility provides for at least 48-months of interest only payments. MAU868 has the potential to neutralize infection by blocking BKV virions from binding to host cells. CEO Marshall Fordyce notes that BK is a leading cause of kidney transplant loss and transplant-associated morbidity, with no currently available antiviral treatments in the US and potential to significantly impact outcomes for these kidney transplant patients (provide a new standard of care). Up to 90 percent of healthy adults are infected with BKV, but it remains latent in kidney and bladder tissues. Reactivation occurs in the setting of immune suppression, and causes clinical disease in the transplant setting. BKV is a significant cause of complications in immunocompromised patients, including in kidney transplant and hematopoietic stem cell transplant (HSCT) recipients. In kidney transplant recipients, BKV is a leading cause of allograft loss and poor outcomes, while in HSCT recipients, the virus significantly increases the risk of severe hemorrhagic cystitis, which causes bladder damage. Corporate Slides Figure 7: BKV is a leading cause of allograft loss (Source: corporate presentation) Positive interim phase 2 data was reported in June, showing that MAU868 was well tolerated and demonstrated significant BK antiviral activity in kidney transplant recipients with BK viremia. Corporate Slides Figure 8: Antiviral and renal effect versus placebo at week 12 (Source: corporate presentation) Playing devil's advocate, I think given details of the deal including low upfront payment, perhaps the market assigns little to no value to this asset until a phase 3 win is achieved or even a regulatory green light. Other Information For the second quarter of 2022, the company reported cash and equivalents of $131.9M (along with access to $45M credit facility) as contrasted to net cash used in operating activities for past six months of $28M (nearing triple the prior year). Quarterly net loss was $14.9M. My estimation is that the company (conservatively) has operational runway of 2 years with current resources at its disposal, so I would not be surprised to see further dilution via secondary offering by mid 2023 or so. Accumulated deficit so far is a reasonable $124.1M. As for prior financings, I consider it a green flag that February's upsized offering took place at $15/share (nearly 30% lower than current levels). For those wanting to learn more about the value proposition behind MAU868, the March webinar was quite helpful for me. Here are a few nuggets: Patients undergo kidney transplant and then put under immune suppression can have reactivation of BK virus that threatens survival of their transplanted kidney. This is a major clinical problem (risk to their new kidney), although BK Virus nephropathy is not a well-known disease. Dr. Jordan, the Director of Nephrology and Transplant Immunology at Cedars-Sinai, states that BK Virus is an opportunistic infection associated with significant morbidity and mortality in transplant patients. Virus finds a home, is dormant and in immuno-suppressed patients is reactivated, starts killing the graft cells and eventually kills the kidney. Main risk factor is overall degree of immunosuppression. Mainstay of management at this time is reducing immunosuppression which has deleterious side effect of increasing risk for rejection. 100,000 kidney transplants are done worldwide each year. Reactivation occurs in about 40% of these patients (virus starts appearing in the urine and if it persists, it appears in the blood). If it persists, you know you are going to get damage to the kidney (kidney function can deteriorate rapidly). If physician resorts to lowering immunosuppression (current standard of care), 12% of patients have rejection of organ (KOL thinks in his experience it's much more than 12%). Devil's advocate, again 12% would seem like a low percent overall and I'm still not sure the market potential for such an asset, not to mention adoption that would occur IF it is approved. On the other hand, data shows that standard of care (immunosuppression reduction) is not a good idea in many cases as it could allow patient's kidney to be rejected by the immune system. MAU868 neutralizes all four genotypes of BK Virus at subnanomolar concentrations. This mechanism of neutralization is proven and effective as seen in other approved monoclonal antibody therapies. In vitro it has been shown to be more potent than IVIG. Administration could be to patients before evidence of BKV replication in plasma as prophylaxis, preemptively at early stages of BKV infection or after disease diagnosis in treatment perspective. Optimal positioning may be in prophylactic high-risk patient or preemptively. As for institutional investors of note, Longitude Capital Partner owns a 12.7% stake and RA Capital owns a 7.5% stake. As for insiders, CEO Marshall Fordyce owns 181,500 shares but constant insider sells over the past few months are not inspiring confidence. As for relevant leadership experience, Chief Medical Officer Celia Lin served prior as Senior Medical Director at Genentech (responsible for phase 3 global study execution and regulatory filing in orphan disease). Chief Development Officer Joane Curley prior led Project and Portfolio Management at Gilead Sciences. Similarly, SVP Development Operations Tom Doan also came from Gilead where he served as Executive Director, Clinical Operations Head of the Inflammation/Respiratory Therapeutic Area.

Biotechs 収益成長	25.5%
収益成長率	54.3%
将来の株主資本利益率	n/a
アナリストカバレッジ	Good
最終更新日	19 May 2026

日付	収益	収益	フリー・キャッシュフロー	営業活動によるキャッシュ	平均アナリスト数
12/31/2028	696	27	82	-71	9
12/31/2027	269	-272	130	-276	11
12/31/2026	43	-442	-337	-400	11
3/31/2026	N/A	-369	-294	-293	N/A
12/31/2025	N/A	-300	-242	-241	N/A
9/30/2025	N/A	-252	-211	-210	N/A
6/30/2025	N/A	-218	-187	-185	N/A
3/31/2025	N/A	-175	-156	-155	N/A
12/31/2024	N/A	-152	-136	-135	N/A
9/30/2024	N/A	-134	-121	-121	N/A
6/30/2024	N/A	-108	-107	-107	N/A
3/31/2024	N/A	-94	-100	-100	N/A
12/31/2023	N/A	-96	-92	-92	N/A
9/30/2023	N/A	-103	-88	-88	N/A
6/30/2023	N/A	-107	-84	-84	N/A
3/31/2023	N/A	-102	-85	-85	N/A
12/31/2022	N/A	-89	-68	-68	N/A
9/30/2022	N/A	-73	-58	-53	N/A
6/30/2022	N/A	-56	-45	-40	N/A
3/31/2022	N/A	-45	-34	-29	N/A
12/31/2021	N/A	-33	-29	-24	N/A
9/30/2021	N/A	-59	-45	-45	N/A
6/30/2021	N/A	-55	-42	-42	N/A
3/31/2021	N/A	-56	-37	-37	N/A
12/31/2020	N/A	-53	-35	-35	N/A

データ	最終更新日（UTC時間）
企業分析	2026/05/20 20:23
終値	2026/05/20 00:00
収益	2026/03/31
年間収益	2025/12/31

パッケージ	データ	タイムフレーム	米国ソース例
会社財務	10年	損益計算書キャッシュ・フロー計算書貸借対照表	SECフォーム10-K SECフォーム10-Q
アナリストのコンセンサス予想	+プラス3年	予想財務アナリストの目標株価	アナリストリサーチレポート Blue Matrix
市場価格	30年	株価配当、分割、措置	ICEマーケットデータ SECフォームS-1
所有権	10年	トップ株主インサイダー取引	SECフォーム4 SECフォーム13D
マネジメント	10年	リーダーシップ・チーム取締役会	SECフォーム10-K SECフォームDEF 14A
主な進展	10年	会社からのお知らせ	SECフォーム8-K

アナリスト	機関
Dina Ramadane	BofA Global Research
Pete Stavropoulos	Cantor Fitzgerald & Co.
Gavin Clark-Gartner	Evercore ISI

Vera Therapeutics 将来の成長

Future 基準チェック /56

主要情報

今後の成長に関する最新情報

Price target increased by 17% to US$55.80

Price target increased by 36% to US$32.11

Price target increased by 12% to US$22.14

Price target increased by 16% to US$18.50

Price target increased by 10% to US$16.00

Price target decreased by 10% to US$14.50

Recent updates

Founder notifies of intention to sell stock

Vera Therapeutics Eyes Mid 2026 Atacicept Launch as FDA Sets July Decision Date

Vera Therapeutics, Inc., Annual General Meeting, May 21, 2026

Vera Therapeutics, Inc. Appoints Jane Wright-Mitchell as Chief Legal Officer, Effective March 25, 2026

Vera Therapeutics Appoints Christopher Hite as Independent Board Member

Vera Therapeutics: Hold Rating Based On Potential For Atacicept In IgAN (Rating Downgrade)

Vera Therapeutics Announces Appointment of Matt Skelton as Chief Commercial Officer, Effective January 28, 2026

Vera Therapeutics, Inc. Announces U.S. FDA Granted Priority Review to Biologics License Application for Atacicept for Treatment of Adults with IgA Nephropathy

Vera Therapeutics, Inc. Announces Departure of Jason Carter as Chief Legal Officer, Effective December 24, 2025

Vera Therapeutics, Inc. has completed a Follow-on Equity Offering in the amount of $260.86959 million.

Vera Therapeutics, Inc. has filed a Follow-on Equity Offering in the amount of $200 million.

Vera Therapeutics, Inc. Appoints James R. Meyers to Its Board of Directors

Vera Therapeutics, Inc. Submits Biologics License Application to U.S. FDA Through Accelerated Approval Program for Atacicept for Treatment of Adults with IgA Nephropathy

Vera Therapeutics, Inc. Announces Origin 3 Late-Breaking Abstract Selected as Featured Oral Presentation At Opening Plenary Session of Asn Kidney Week 2025

Vera Therapeutics, Inc. has filed a Follow-on Equity Offering in the amount of $200 million.

Is Vera Therapeutics (NASDAQ:VERA) Weighed On By Its Debt Load?

Vera Therapeutics, Inc. Announces Atacicept Achieves 46% Proteinuria Reduction in ORIGIN Phase 3 Trial in Adults with IgA Nephropathy

Vera Therapeutics, Inc., Annual General Meeting, May 14, 2025

Vera Therapeutics, Inc. Completes Full Enrollment in Pivotal ORIGIN Phase 3 Trial for Atacicept in IgAN

Is Vera Therapeutics (NASDAQ:VERA) Weighed On By Its Debt Load?

Vera Therapeutics: Does The Earlier Otsuka Launch Harm Its Prospects Much?

Vera Therapeutics: Strong Data In IgAN, But We May Be Too Late

Vera Therapeutics, Inc. Appoints Jason S. Carter as Chief Legal Officer

Vera Therapeutics, Inc. has completed a Follow-on Equity Offering in the amount of $300.000036 million.

Vera Therapeutics, Inc. has filed a Follow-on Equity Offering in the amount of $300 million.

Vera Therapeutics, Inc. Announces 96-week eGFR Stabilization in ORIGIN Phase 2b Study of Atacicept in IgAN at the American Society of Nephrology Kidney Week 2024

Is Vera Therapeutics (NASDAQ:VERA) A Risky Investment?

Vera: Potential First Of Atacicept As A B-Cell Modulator For IgAN Patients

Vera Therapeutics, Inc. Announces Expanded Atacicept Development Program in Multiple Autoimmune Kidney Diseases

Vera Therapeutics' Atacicept: A Potential Game-Changer In IgA Nephropathy

Is Vera Therapeutics (NASDAQ:VERA) Using Debt In A Risky Way?

Vera Therapeutics, Inc.(NasdaqGM:VERA) dropped from Russell 3000E Value Index

Vera Therapeutics, Inc. Announces Appointment of David L. Johnson as Chief Operating Officer

Vera Therapeutics, Inc. Appoints Christy Oliger to the Board

Vera Therapeutics, Inc. Presents 72-Week eGFR Stabilization and Rapid Hematuria Improvement in Phase 2b ORIGIN Study of Atacicept in IgAN at the 61st European Renal Association Congress

Insider exercised options and sold US$1.0m worth of stock

Insider recently sold US$229k worth of stock

Price target increased by 17% to US$55.80

Chief Financial Officer recently sold US$735k worth of stock

Chief Financial Officer notifies of intention to sell stock

Vera Therapeutics, Inc., Annual General Meeting, May 15, 2024

Vera Therapeutics, Inc. has completed a Follow-on Equity Offering in the amount of $250.000027 million.

Vera Therapeutics, Inc. has filed a Follow-on Equity Offering in the amount of $200 million.

Price target increased by 36% to US$32.11

New minor risk - Share price stability

Vera Therapeutics: Soaring On IgAN Data, But Full Approval A Distant Prospect

Vera Therapeutics, Inc. Presents Positive 72-Week Data Showing eGFR Stabilization in the Phase 2b Origin Clinical Trial Ole in IgA Nephropathy

Vera Therapeutics, Inc. Announces Executive Changes

New minor risk - Share price stability

Price target increased by 12% to US$22.14

New major risk - Revenue and earnings growth

Price target increased by 16% to US$18.50

Price target increased by 10% to US$16.00

Price target decreased by 10% to US$14.50

New minor risk - Share price stability

Vera Therapeutics Appoints Kerry Cooper, M.D., as Senior Vice President of Medical Affairs

Price target decreased by 18% to US$15.67

Chief Financial Officer recently bought US$100k worth of stock

Vera Therapeutics, Inc. has completed a Follow-on Equity Offering in the amount of $100.000005 million.

Vera Therapeutics, Inc. Releases 36 Week Interim Analysis of Phase 2b Clinical Trial of Atacicept for the Treatment of IgA Nephropathy

Vera Therapeutics, Inc. Hosting A Key Opinion Leader Webinar on Atacicept for the Treatment Iga Nephropathy (Igan)

Price target decreased to US$19.17

Vera Therapeutics, Inc. Announces Positive Topline Results of Phase 2b ORIGIN Clinical Trial of Atacicept for the Treatment of IgA Nephropathy

Chief Development Officer exercised options and sold US$148k worth of stock

Founder exercised options to buy US$1.1m worth of stock.

High number of new directors

Chief Development Officer exercised options and sold US$95k worth of stock

Founder exercised options and sold US$576k worth of stock

Chief Development Officer exercised options and sold US$186k worth of stock