お知らせ • Oct 29
Actinium Pharmaceuticals, Inc. Announces Executive Changes
Actinium Pharmaceuticals, Inc. announced broad senior level expansion of its clinical organization. These key hires strengthen the Company's expertise in hematological malignancies, bone marrow transplant (BMT) and radiation sciences as well its operational capabilities. The addition of Madhuri Vusirikala, MD, Vice President of Clinical Development, BMT and Cellular Therapy, and Akash Nahar, MD, Vice President of Clinical Development, are complemented by the deep nuclear medicine and radiation science expertise with Patrik Brodin, Ph.D., Vice President of Radiation Sciences. Elaina Haeuber, Vice President, Head of Clinical Operations, will lead the clinical operations organization to further support the Company's clinical development plans for its pipeline products including Iomab-B and Actimab-A. As previously announced, Actinium is preparing to report topline data from its pivotal Phase 3 SIERRA trial for Iomab-B in the fourth quarter of this year. Madhuri Vusirikala, MD – Vice President, Clinical Development BMT and Cellular Therapy: Dr. Vusirikala is an accomplished bone marrow transplant physician and hematologist with over 20 years of clinical experience. She is board certified in internal medicine, hematology and oncology. Dr. Vusirikala joins Actinium from UT Southwestern Medical Center in Dallas, Texas, where she has been a Professor of Internal Medicine in the Division of Hematology/Oncology and Medical Director of the Adult Allogeneic Bone Marrow Transplant Program. She specialized in managing a variety of hematologic malignancies and performing allogeneic bone marrow transplants for these patients when indicated. She also served as primary investigator for most of the clinical trials at UT Southwestern related to BMT. Dr. Vusirikala earned her medical degree (M.B.B.S.) at India's Lady Hardinge Medical College before completing an internal medicine internship at Maulana Azad Medical College-Delhi University and an internal medicine internship and residency at The State University of New York, Syracuse. She also completed a hematology and oncology fellowship at the University of Pittsburgh and an advanced fellowship in bone marrow transplantation at Vanderbilt University Medical Center. Dr. Vusirikala is a member of the American Society of Hematology, American Society of Transplantation and Cellular Therapy. She serves as a member on the NCCN panels for Hematopoietic Cell Transplantation and Acute Lymphoblastic Leukemia committees. Akash Nahar, MD – Vice President, Clinical Development: Dr. Nahar brings over 15 years of hematology-oncology research and development experience in academia and industry. Previously, Dr. Nahar held positions of increasing responsibilities, most recently serving as Global Product Development Lead for hematology programs at Merck. In this role, he led a team of six physicians responsible for the development of the PD-1 inhibitor Keytruda® in Hodgkin's lymphoma along with other developmental products for hematological malignancies. Dr. Nahar successfully led the filing of two indications for Keytruda®. He made impactful contributions cross-functionally, including clinical research, strategy, and regulatory, spanning multiple hematological indications. He also brings experience from all phases of drug development, successfully executing programs from early phase 1 through approval. Dr. Nahar is board certified in pediatrics and hematology/oncology. He is a faculty member in oncology at St. Christopher's Hospital for Children in Philadelphia and an Associate Professor in pediatrics at Drexel University. He has authored multiple papers and book chapters and have published several papers in peer reviewed journals. Dr. Nahar received his Bachelor of Medicine and Bachelor or Surgery (MBBS) from Mahatma Gandhi Memorial Medical College, Indore, India and his MPH in Epidemiology from the State University of New York at Albany. Patrik Brodin, MSc, PhD – Vice President, Head of Radiation Sciences: Patrik is a board certified Medical Physicist, and a Diplomat of the American Board of Radiology in the discipline of Therapeutic Medical Physics, and previously, was an Assistant Professor and Senior Physicist at the department of Radiation Oncology at Montefiore/Einstein. By combining his expertise in radiation physics and data analysis with biology-based research methods, he spearheaded the development of new approaches in radiation-driven immunotherapy, and solutions for reducing the risk of severe treatment complications associated with receiving high-dose radiation therapy. Patrik has experience and expertise in clinical medical physics, biostatistics and advanced analytical methods including quantitative image analysis, and novel experimental design. He has authored more than 60 peer-reviewed publications and presented at national and international meetings including oral presentations at the ESTRO, ASTRO, AAPM and PTCOG annual meetings. Patrik trained in Medical Physics at Lund University, Sweden, followed by a PhD at the Niels Bohr Institute at the University of Copenhagen, Denmark, and received his M.Sc. in Clinical Research Methods from Yeshiva University upon coming to the United States. Elaina Haeuber, MS – Vice President, Head of Clinical Operations: Elaina brings more than 20 years of clinical research operations and project management experience in the biopharmaceutical industry. Most recently, she was Vice President, Operations at WCG, a global organization supporting various aspect of clinical trials where she was responsible for overseeing data safety monitoring boards and independent event adjudication for numerous clinical studies. Prior to this, she was Executive Director, Operations Management for oncology and hematology trials at Syneos Health. Elaina has overseen regional and global project and clinical management teams of up to 300 staff and managed a strategic biopharma portfolio at PPD, which included more than 60 studies in multiple therapeutic areas. Her oncology experience includes all phases of studies across multiple indications, cell and gene therapy, immuno- and targeted therapies. She has supported programs leading to marketing approval in both the US and EMA including PD-L1 inhibitor Tecentriq approved in non-small cell lung cancer, small cell lung cancer, triple negative breast cancer and other indications, Zynteglo, the first cell-based gene therapy approved for patients with beta-thalassemia, and Skysona, a gene therapy for patients with early, active cerebral adrenoleukodystrophy (CALD). While at PPD, she supported the merger of two independent business units (Acurian and Synexus) into an integrated business unit called Accelerated Enrollment Solutions, as well as played a key role in designing a decentralized clinical trial model to better manage their large clinical trial operations. She has a BA from Boston University and an MS from the University of Illinois.
