Rhythm Pharmaceuticals (RYTM) Panoramica del titolo
Rhythm Pharmaceuticals, Inc. è un'azienda biofarmaceutica in fase di commercializzazione che si concentra sulle malattie neuroendocrine rare negli Stati Uniti e a livello internazionale. Maggiori dettagli
| Punteggio fiocco di neve | |
|---|---|
| Valutazione | 3/6 |
| Crescita futura | 5/6 |
| Prestazioni passate | 0/6 |
| Salute finanziaria | 4/6 |
| Dividendi | 0/6 |
Premi
Analisi del rischio
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RYTM Community Fair Values
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Analyst Price Targets
Concorrenti di Rhythm Pharmaceuticals, Inc.
Storia dei prezzi e prestazioni
| Prezzi storici delle azioni | |
|---|---|
| Prezzo attuale dell'azione | US$90.52 |
| Massimo di 52 settimane | US$122.20 |
| Minimo di 52 settimane | US$58.71 |
| Beta | 1.94 |
| Variazione di 1 mese | 2.74% |
| Variazione a 3 mesi | -7.70% |
| Variazione di 1 anno | 51.04% |
| Variazione a 3 anni | 439.77% |
| Variazione a 5 anni | 319.27% |
| Variazione dall'IPO | 201.73% |
Notizie e aggiornamenti recenti
Aggiornamento della narrazione • May 04
RYTM: Hypothalamic Obesity Expansion Will Drive Next Phase Of Upside
Rhythm Pharmaceuticals' consolidated analyst price target has been adjusted slightly higher by a few dollars to $137.67, as analysts update their models around recent EMANATE trial outcomes, hypothalamic obesity launch expectations, and evolving views on next generation MC4R agonist opportunities. Analyst Commentary Recent research updates show a mix of optimism and caution around Rhythm Pharmaceuticals, with several firms adjusting price targets both higher and lower as they factor in EMANATE outcomes, hypothalamic obesity indications, and next generation MC4R agonist programs.Aggiornamento della narrazione • Apr 19
RYTM: Hypothalamic Obesity Approval Will Drive Next Phase Of Upside
Analysts have nudged their blended price target for Rhythm Pharmaceuticals higher by $0.40 to $137.67, reflecting updated assumptions around revenue growth, profitability, discount rates, and future P/E multiples following recent research updates on Phase 3 trial outcomes and the commercial outlook for Imcivree and hypothalamic obesity. Analyst Commentary Recent research updates present a mixed but generally constructive picture, with several firms adjusting price targets following the EMANATE trial results and evolving expectations for Imcivree and hypothalamic obesity.Aggiornamento della narrazione • Apr 04
RYTM: Hypothalamic Obesity Expansion Will Drive Next Upside Phase
Rhythm Pharmaceuticals' fair value estimate has moved higher to $137.27 from $135.53, as analysts factor in recent price target revisions that balance EMANATE trial setbacks with continued focus on Imcivree commercial execution and next generation MC4R agonists. Analyst Commentary Street research around Rhythm Pharmaceuticals has shifted meaningfully following the EMANATE readout, with price targets adjusted both higher and lower as analysts weigh clinical risk against the commercial rollout of Imcivree and the potential of next generation MC4R agonists.Recent updates
Aggiornamento della narrazione • May 04
RYTM: Hypothalamic Obesity Expansion Will Drive Next Phase Of Upside
Rhythm Pharmaceuticals' consolidated analyst price target has been adjusted slightly higher by a few dollars to $137.67, as analysts update their models around recent EMANATE trial outcomes, hypothalamic obesity launch expectations, and evolving views on next generation MC4R agonist opportunities. Analyst Commentary Recent research updates show a mix of optimism and caution around Rhythm Pharmaceuticals, with several firms adjusting price targets both higher and lower as they factor in EMANATE outcomes, hypothalamic obesity indications, and next generation MC4R agonist programs.Aggiornamento della narrazione • Apr 19
RYTM: Hypothalamic Obesity Approval Will Drive Next Phase Of Upside
Analysts have nudged their blended price target for Rhythm Pharmaceuticals higher by $0.40 to $137.67, reflecting updated assumptions around revenue growth, profitability, discount rates, and future P/E multiples following recent research updates on Phase 3 trial outcomes and the commercial outlook for Imcivree and hypothalamic obesity. Analyst Commentary Recent research updates present a mixed but generally constructive picture, with several firms adjusting price targets following the EMANATE trial results and evolving expectations for Imcivree and hypothalamic obesity.Aggiornamento della narrazione • Apr 04
RYTM: Hypothalamic Obesity Expansion Will Drive Next Upside Phase
Rhythm Pharmaceuticals' fair value estimate has moved higher to $137.27 from $135.53, as analysts factor in recent price target revisions that balance EMANATE trial setbacks with continued focus on Imcivree commercial execution and next generation MC4R agonists. Analyst Commentary Street research around Rhythm Pharmaceuticals has shifted meaningfully following the EMANATE readout, with price targets adjusted both higher and lower as analysts weigh clinical risk against the commercial rollout of Imcivree and the potential of next generation MC4R agonists.Aggiornamento della narrazione • Mar 20
RYTM: Hypothalamic Obesity Approval And Launch Preparations Will Drive Next Upside Phase
The updated analyst model trims the blended price target for Rhythm Pharmaceuticals by about $4 to $135.53 as analysts factor in slightly lower revenue growth and margin assumptions, along with a higher projected future P/E multiple following recent EMANATE trial results and ongoing focus on Imcivree and hypothalamic obesity. Analyst Commentary Recent Street research around Rhythm Pharmaceuticals reflects a mixed but engaged view, with several firms adjusting price targets after EMANATE and other trial updates, as well as ongoing focus on Imcivree and hypothalamic obesity.Aggiornamento della narrazione • Mar 06
RYTM: Hypothalamic Obesity Launch And Upcoming Data Readouts Will Drive Next Upside Phase
Analysts trimmed their blended price target for Rhythm Pharmaceuticals by a few dollars, reflecting slightly more conservative long-term revenue and margin assumptions, even as they continue to highlight the potential of IMCIVREE and the hypothalamic obesity opportunity. Analyst Commentary Recent Street research around Rhythm Pharmaceuticals shows a mix of enthusiasm about the IMCIVREE franchise and the hypothalamic obesity opportunity, along with some recalibration of long-term expectations that feeds into updated price targets.
Nuova narrazione • Feb 21
Rare Obesity Leadership: Can Setmelanotide Scale Beyond the Clinic?
Rhythm Pharmaceuticals enters late February 2026 as the leader in "rare disease obesity," a niche that has remained remarkably insulated from the broader GLP-1 price wars. The company’s core asset, Setmelanotide , has seen rapid uptake in patients with Bardet-Biedl syndrome (BBS) and POMC deficiency, where traditional weight-loss drugs often fail.Aggiornamento della narrazione • Feb 18
RYTM: Stable Franchise Trends Will Support Next Phase Of Upside
Analysts have lifted their price target on Rhythm Pharmaceuticals to $145 from $140, citing slightly stronger than expected preannounced Q4 Imcivree revenue of about $57M and what they see as stable growth trends for the existing franchise. Analyst Commentary Recent commentary centers on how the preannounced Q4 Imcivree revenue of about US$57M feeds into expectations for Rhythm Pharmaceuticals' execution and valuation.Aggiornamento della narrazione • Feb 04
RYTM: March Review Decision Will Drive Next Phase Of Upside
Analysts lifted their price target on Rhythm Pharmaceuticals to US$145 from US$140, citing Q4 Imcivree revenues of about US$57 million coming in slightly ahead of expectations and their view that growth in the existing franchise remains stable. Analyst Commentary Recent commentary around Rhythm Pharmaceuticals focuses on how the latest Imcivree revenue update might influence expectations for growth, execution, and valuation.Aggiornamento della narrazione • Jan 21
RYTM: March Hypothalamic Obesity Decision Will Drive Next Phase Of Upside
Narrative Update Overview Analysts have inched their fair value estimate for Rhythm Pharmaceuticals higher to about $140 from $139, reflecting slightly higher Street price targets and expectations for steady Imcivree demand after a Q4 revenue preannouncement of roughly $57 million. The update also takes into account more cautious views on how much near term upside is left around upcoming label and trial milestones.Aggiornamento della narrazione • Jan 06
RYTM: March Obesity Decision And Prader Willi Data Will Shape Upside
Analysts have nudged their fair value estimate for Rhythm Pharmaceuticals higher to about US$139 per share from roughly US$138, reflecting recent price target increases from several firms, along with views that upcoming label expansion and clinical readouts are already largely reflected in the current share price. Analyst Commentary Recent Street research on Rhythm Pharmaceuticals shows a mix of enthusiasm around the commercial trajectory and upcoming label events, alongside some caution on how much of that story is already reflected in the share price.Aggiornamento della narrazione • Dec 21
RYTM: March FDA Obesity Decision Will Drive Next Phase Of Upside
Analysts have modestly lifted their fair value estimate for Rhythm Pharmaceuticals to approximately $138 from about $127, reflecting slightly higher long term revenue growth expectations and confidence in upcoming hypothalamic obesity label expansion, despite a recent downgrade on valuation concerns. Analyst Commentary Bullish analysts highlight that Rhythm's strong clinical execution in hypothalamic obesity and Bardet Biedl syndrome, along with robust year to date share performance, support a higher long term revenue trajectory and justify incremental price target increases.Seeking Alpha • Dec 11
Rhythm: PWS Signal, HO Speed Bump, And The Case For A Rare-Obesity Blockbuster
Summary Rhythm Pharmaceuticals, Inc. remains a compelling rare-disease obesity platform, with a maintained Buy rating driven by progress in HO, PWS, and oral MC4R agonists. PWS Phase 2 data for IMCIVREE show early efficacy in BMI and hyperphagia reduction, though limited by small sample size and responder heterogeneity. RYTM's HO sNDA PDUFA was delayed to March 2026 for additional FDA analysis, but I remain optimistic on approval with some risk to pediatric labeling. IMCIVREE's current indications provide a revenue floor, while upside hinges on HO approval, PWS data de-risking, and successful oral franchise transition. Read the full article on Seeking AlphaAggiornamento della narrazione • Dec 07
RYTM: March FDA Obesity Decision Will Drive Next Phase Of Share Upside
Analysts have edged their average price target for Rhythm Pharmaceuticals slightly higher to about $127 from roughly $126, reflecting confidence that strong Imcivree and bivamelagon data, along with anticipated hypothalamic obesity label expansion, can support continued growth. However, recent gains and a limited near term catalyst slate are tempering enthusiasm.Aggiornamento della narrazione • Nov 23
RYTM: December FDA Decision Will Drive Next Phase Of Share Upside
Rhythm Pharmaceuticals' analyst price target increased from $121.43 to $126.31, as analysts cite ongoing clinical progress and upcoming regulatory milestones that support further upside for the company’s shares. Analyst Commentary Analysts have recently weighed in on Rhythm Pharmaceuticals, offering both optimistic and cautionary perspectives based on the company's performance, upcoming catalysts, and valuation.Articolo di analisi • Nov 07
The Rhythm Pharmaceuticals, Inc. (NASDAQ:RYTM) Third-Quarter Results Are Out And Analysts Have Published New Forecasts
It's been a sad week for Rhythm Pharmaceuticals, Inc. ( NASDAQ:RYTM ), who've watched their investment drop 12% to...Aggiornamento della narrazione • Nov 05
RYTM: Upcoming FDA Decision Will Drive Next Phase of Upside Momentum
Analysts have raised their price target for Rhythm Pharmaceuticals from $117.57 to $121.43 per share, citing improved profit margin projections and increased optimism about upcoming label expansions for setmelanotide. Analyst Commentary Recent updates from Street research provide a balanced view on Rhythm Pharmaceuticals, with both bullish and bearish perspectives influencing the company's outlook and valuation.Aggiornamento della narrazione • Oct 22
Analysts Boost Rhythm Pharmaceuticals Outlook Amid Setmelanotide Progress and Revised Valuation Metrics
The analyst price target for Rhythm Pharmaceuticals was revised upward by $7 to reflect increased optimism from analysts about the company's potential label expansion and expected regulatory progress for setmelanotide in hypothalamic obesity. Analyst Commentary Recent updates from Street research indicate a positive reassessment of Rhythm Pharmaceuticals' prospects, particularly surrounding potential regulatory approval and expanding commercial opportunities for setmelanotide in hypothalamic obesity.Aggiornamento della narrazione • Oct 08
Rising Genetic Diagnosis Will Expand Rare Disease Treatment Pipelines
Rhythm Pharmaceuticals' analyst price target has increased from $114.86 to $118.36, as analysts cite encouraging clinical data and optimism about setmelanotide's approval prospects in hypothalamic obesity. These factors are driving the revised valuation.Aggiornamento della narrazione • Sep 24
Rising Genetic Diagnosis Will Expand Rare Disease Treatment Pipelines
The consensus price target for Rhythm Pharmaceuticals was raised to $114.86 as bullish analyst sentiment strengthened on strong Phase 2 obesity trial results, robust Imcivree sales, and optimistic expectations for regulatory milestones and long-term franchise durability. Analyst Commentary Bullish analysts highlight strong Phase 2 trial results for bivamelagon in hypothalamic obesity, demonstrating significant placebo-adjusted BMI reduction at multiple doses and exceeding expectations for efficacy over 14 weeks.Aggiornamento della narrazione • Aug 07
Rising Genetic Diagnosis Will Expand Rare Disease Treatment Pipelines
A lower future P/E indicates improved earnings expectations, while a higher discount rate suggests increased perceived risk, yet analysts have still raised Rhythm Pharmaceuticals’ fair value to $110.71 per share. What's in the News Rhythm Pharmaceuticals presented new clinical data on bivamelagon (oral MC4R agonist) and setmelanotide (lead asset) in patients with acquired hypothalamic obesity at ENDO 2025; setmelanotide remains FDA approved for syndromic monogenic obesity due to defined genetic deficiencies.Articolo di analisi • Jul 10
Revenues Not Telling The Story For Rhythm Pharmaceuticals, Inc. (NASDAQ:RYTM) After Shares Rise 33%
Rhythm Pharmaceuticals, Inc. ( NASDAQ:RYTM ) shares have continued their recent momentum with a 33% gain in the last...Articolo di analisi • Jun 25
Rhythm Pharmaceuticals (NASDAQ:RYTM) Has Debt But No Earnings; Should You Worry?
Legendary fund manager Li Lu (who Charlie Munger backed) once said, 'The biggest investment risk is not the volatility...Nuova narrazione • May 26
Label Expansion And Global Healthcare Will Widen Future Market Opportunities
Label expansion and global commercialization of IMCIVREE are set to drive substantial revenue growth and broaden market reach.Seeking Alpha • Apr 08
Rhythm: Late-Stage Study Win Brings About Change For Rare Obesity Disorder
Summary Rhythm Pharmaceuticals, Inc. met primary endpoint in phase 3 TRANSCEND study, which used setmelanotide for the treatment of patients with acquired hypothalamic obesity. Regulatory submission of setmelanotide to the U.S. and EU, for the treatment of patients with acquired hypothalamic obesity, expected in Q3 of 2025. Company pushing forward with oral MC4R-specific agonist to treat patients with acquired hypothalamic obesity known as bivamelagon; Data from a phase 1/2 study, using bivamelagon for the treatment of patients with acquired hypothalamic obesity, expected in 2nd half of 2025. Read the full article on Seeking AlphaSeeking Alpha • Feb 25
Rhythm Pharmaceuticals: Buying This Rare Genetic Obesity Maven
Summary Rhythm Pharmaceuticals' 01/2025 presentation and Q4 2024 preliminary results press release highlight growing financial performance and promising pipeline developments. Investment thesis focuses on Rhythm's robust clinical progress and strategic positioning in the rare genetic obesity market. Rating justification is based on solid revenues, innovative product pipeline, and potential market expansion. Conclusion emphasizes Rhythm's growth potential and recommends it as a compelling speculative investment opportunity. Read the full article on Seeking AlphaSeeking Alpha • Dec 06
Rhythm Pharmaceuticals: A Key Year Ahead
Summary Rhythm Pharmaceuticals, Inc.'s main asset, imcivree, targets rare genetic obesity disorders; key milestones in 2025 could significantly impact the stock. Positive Phase 3 data and expanded indications for imcivree, including Hypothalamic Obesity, are crucial for future growth. Analysts are optimistic, with multiple Buy ratings and price targets between $65-$80; however, insiders have sold some shares recently. An updated analysis around Rhythm Pharmaceuticals follows in the paragraphs below. Read the full article on Seeking AlphaSeeking Alpha • Sep 22
Rhythm: Upcoming sNDA Label Expansion IMCIVREE Isn't The Only Catalyst On Deck
Summary IMCIVREE is FDA-approved for obesity due to genetic mutations and aims to expand its label to include children as young as 2 years old. Rhythm is also exploring IMCIVREE for hypothalamic obesity in a phase 3 study, with data expected in the 1st half of 2025. Financially, Rhythm has $319.1 million in cash, but may need to raise more funds within the next 12 months. RM-718 and LB54640 are two other drugs being developed to treat patients with hypothalamic obesity; Both of which are able to achieve function without hyperpigmentation. Read the full article on Seeking AlphaSeeking Alpha • Aug 29
Rhythm: Pivotal Moment Approaching In Hypothalamic Obesity (Rating Upgrade)
Summary Rhythm Pharmaceuticals' Q2 revenue rose to $29.1 million, driven by global sales of Imcivree, its treatment for rare genetic obesity disorders. The company's cash and investments totaled $319 million by June 30, 2024, ensuring a cash runway into 2026, according to Rhythm's projections. Imcivree is currently undergoing a Phase 3 trial for hypothalamic obesity, with results expected in 1H 2025, crucial for its potential blockbuster status. RYTM stock is a speculative "buy" based on the potential of Imcivree in treating hypothalamic obesity, though there are significant risks if the trial fails. Read the full article on Seeking AlphaSeeking Alpha • Jun 12
Rhythm: Navigating Imcivree's Potential In Rare Obesity Treatments (Rating Upgrade)
Summary Rhythm Pharmaceuticals' stock has appreciated 68% since the last sell recommendation, outperforming market returns. Imcivree shows promising Phase 2 results in treating hypothalamic obesity, potentially doubling its market if its Phase 3 trial proves successful. The company's financial health appears stable, with a sufficient cash runway extended by recent funding. The Phase 3 trial for Imcivree in heterozygous mutations aims to broaden the addressable population to exceed 50,000. I now hold a more balanced view of RYTM stock, acknowledging its strategic expansions but cautious of its high valuation and ongoing risks. Read the full article on Seeking AlphaSeeking Alpha • Feb 23
Rhythm Pharmaceuticals: Action Too Specific
Summary Rhythm Pharmaceuticals focuses on treating obesity caused by genetic mutations, but the market size for these mutations is too small to justify the company's valuation. Novo Nordisk's Ozempic also targets the same patient groups, making Rhythm's product less appealing. IMCIVREE, Rhythm's main product, shows good results in clinical trials, but again the action is too specific. Outstanding dilution from options too down the line. Not for us. Read the full article on Seeking AlphaRendimenti per gli azionisti
| RYTM | US Biotechs | US Mercato | |
|---|---|---|---|
| 7D | -3.9% | -1.6% | -0.9% |
| 1Y | 51.0% | 34.4% | 24.4% |
Ritorno vs Industria: RYTM ha superato il US Biotechs che ha restituito 34.4 % nell'ultimo anno.
Rendimento vs Mercato: RYTM ha superato il mercato US che ha restituito 24.4 % nell'ultimo anno.
Volatilità dei prezzi
| RYTM volatility | |
|---|---|
| RYTM Average Weekly Movement | 7.6% |
| Biotechs Industry Average Movement | 10.8% |
| Market Average Movement | 7.2% |
| 10% most volatile stocks in US Market | 16.2% |
| 10% least volatile stocks in US Market | 3.1% |
Prezzo delle azioni stabile: RYTM non ha avuto una volatilità dei prezzi significativa negli ultimi 3 mesi rispetto al mercato US.
Volatilità nel tempo: La volatilità settimanale ( 8% ) di RYTM è rimasta stabile nell'ultimo anno.
Informazioni sull'azienda
| Fondato | I dipendenti | AMMINISTRATORE DELEGATO | Sito web |
|---|---|---|---|
| 2008 | 414 | David Meeker | rhythmtx.com |
Rhythm Pharmaceuticals, Inc. è una società biofarmaceutica in fase di commercializzazione che si concentra sulle malattie neuroendocrine rare negli Stati Uniti e a livello internazionale. Il candidato principale dell'azienda è IMCIVREE (setmelanotide), un recettore raro della melanocortina-4 per il trattamento dell'obesità da deficit di pro-opiomelanocortina (POMC), proproteina convertasi subtilisina/kexina di tipo 1, recettore della leptina (LEPR), sindrome di Bardet-Biedl e Alström, sindrome di Prader-Willi e obesità ipotalamica. È in fase 3 di sperimentazione clinica per il trattamento dell'obesità ipotalamica acquisita, dell'obesità ipotalamica congenita, dell'obesità da insufficienza di pro-opiomelanocortina (POMC) e LEPR, dell'obesità da deficit di SRC1 e dell'obesità da deficit di SH2B1; e in fase 2 di sperimentazione clinica per il trattamento della sindrome di Prader-Willi e del deficit di MC4R.
Rhythm Pharmaceuticals, Inc. Riepilogo dei fondamenti
| RYTM statistiche fondamentali | |
|---|---|
| Capitalizzazione di mercato | US$6.20b |
| Utili (TTM) | -US$207.84m |
| Ricavi(TTM) | US$217.17m |
28.6x
Rapporto P/S-29.8x
Rapporto P/ERYTM è sopravvalutato?
Vedi Fair Value e analisi di valutazioneUtili e ricavi
| RYTM Conto economico (TTM) | |
|---|---|
| Ricavi | US$217.17m |
| Costo del fatturato | US$23.00m |
| Profitto lordo | US$194.16m |
| Altre spese | US$402.00m |
| Utili | -US$207.84m |
Ultimi utili riportati
Mar 31, 2026
Prossima data di guadagno
n/a
| Utile per azione (EPS) | -3.03 |
| Margine lordo | 89.41% |
| Margine di profitto netto | -95.71% |
| Rapporto debito/patrimonio netto | 45.6% |
Come si è comportato RYTM nel lungo periodo?
Vedi performance storica e confrontoAnalisi aziendale e situazione dei dati finanziari
| Dati | Ultimo aggiornamento (ora UTC) |
|---|---|
| Analisi dell'azienda | 2026/05/16 11:24 |
| Prezzo dell'azione a fine giornata | 2026/05/15 00:00 |
| Utili | 2026/03/31 |
| Utili annuali | 2025/12/31 |
Fonti dei dati
I dati utilizzati nella nostra analisi aziendale provengono da S&P Global Market Intelligence LLC. I seguenti dati sono utilizzati nel nostro modello di analisi per generare questo report. I dati sono normalizzati, il che può comportare un ritardo nella disponibilità della fonte.
| Pacchetto | Dati | Tempistica | Esempio Fonte USA * |
|---|---|---|---|
| Dati finanziari della società | 10 anni |
| |
| Stime di consenso degli analisti | +3 anni |
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| Prezzi di mercato | 30 anni |
| |
| Proprietà | 10 anni |
| |
| Gestione | 10 anni |
| |
| Sviluppi principali | 10 anni |
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* Esempio per i titoli statunitensi, per i titoli non statunitensi si utilizzano forme e fonti normative equivalenti.
Se non specificato, tutti i dati finanziari si basano su un periodo annuale ma vengono aggiornati trimestralmente. Si tratta dei cosiddetti dati TTM (Trailing Twelve Month) o LTM (Last Twelve Month). Per saperne di più.
Modello di analisi e Snowflake
I dettagli del modello di analisi utilizzato per generare questo report sono disponibili sulla nostra pagina Github; abbiamo anche guide su come utilizzare i nostri report e tutorial su Youtube.
Scoprite il team di livello mondiale che ha progettato e realizzato il modello di analisi Simply Wall St.
Metriche di settore e industriali
Le nostre metriche di settore e di sezione sono calcolate ogni 6 ore da Simply Wall St; i dettagli del nostro processo sono disponibili su Github.
Fonti analitiche
Rhythm Pharmaceuticals, Inc. è coperta da 27 analisti. 16 di questi analisti ha fornito le stime di fatturato o di utile utilizzate come input per il nostro report. Le stime degli analisti vengono aggiornate nel corso della giornata.
| Analista | Istituzione |
|---|---|
| Tazeen Ahmad | BofA Global Research |
| Whitney Ijem | Canaccord Genuity |
| Samantha Lynn Semenkow | Citigroup Inc |