iTeos Therapeutics, Inc.

Report azionario NasdaqGM:ITOS

Capitalizzazione di mercato: US$448.7m

This company has been acquired

The company may no longer be operating, as it has been acquired. Find out why through their latest events.

iTeos Therapeutics Gestione

Criteri Gestione verificati 2/4

iTeos Therapeutics Il CEO è Michel Detheux, nominato in Aug2011, e ha un mandato di 13.58 anni. la retribuzione annua totale è $ 6.09M, composta da 10.3% di stipendio e 89.7% di bonus, comprese azioni e opzioni aziendali. possiede direttamente 0.31% delle azioni della società, per un valore di $ 1.41M. La durata media del mandato del team dirigenziale e del consiglio di amministrazione è rispettivamente 5.2 anni e 4.3 anni.

Informazioni chiave

Michel Detheux

Amministratore delegato

US$6.1m

Compenso totale

Percentuale dello stipendio del CEO10.33%
Mandato del CEO14yrs
Proprietà del CEO0.3%
Durata media del management5.2yrs
Durata media del Consiglio di amministrazione4.3yrs

Aggiornamenti recenti sulla gestione

Recent updates

Seeking Alpha • Feb 27

iTeos Therapeutics: Decimated By Collateral Events, Good Chances Of Success Nevertheless

Summary iTeos' lead molecule, Belrestotug, shows promising efficacy in trials despite setbacks in the anti-TIGIT space, with significant partnerships and a strong cash position. The stock has suffered due to failures of similar molecules from competitors, but iTeos' data remains positive, attracting major investments. Financially, iTeos has a solid runway with a market cap of $255mn and cash reserves nearly twice that, ensuring stability. Despite risks, the potential market for anti-TIGIT treatments is vast, and iTeos' strategic partnership with GSK positions it for future success. Read the full article on Seeking Alpha
Seeking Alpha • Dec 18

iTeos Therapeutics: A Perhaps Unjustified Decline To End 2024

Summary iTeos Therapeutics, Inc.'s lead candidate, belrestotug, shows promising response rates in lung cancer but faces challenges with increased toxicity and skepticism due to past failures in similar approaches. The company's financial health is strong, with over half a billion dollars in liquid assets and long-term investments, providing a substantial cushion for ongoing projects. Despite shelving inupadenant, the focus remains on belrestotug, with ongoing trials exploring its potential in various cancer indications. Given the promising data and financial runway, I maintain a Buy sentiment on ITOS stock, despite the inherent risks and market pessimism. Read the full article on Seeking Alpha
Articolo di analisi • Nov 15

iTeos Therapeutics, Inc. (NASDAQ:ITOS) Third-Quarter Results: Here's What Analysts Are Forecasting For Next Year

iTeos Therapeutics, Inc. ( NASDAQ:ITOS ) shareholders are probably feeling a little disappointed, since its shares fell...
Seeking Alpha • Sep 15

iTeos Therapeutics: ESMO Data Showing Signs Of A Real Win For TIGIT

Summary iTeos Therapeutics' belrestotug shows promising response rates in lung cancer trials, especially when combined with dostarlimab, despite significant safety concerns. Financially, ITOS has over 3 years of cash runway, bolstered by collaboration revenue, supporting its potential to reach critical milestones. The risks include small trial size, potential non-translation of response rates to survival benefits, and high-grade toxicities that could hinder approval. Despite risks, ITOS's market cap of $600 million suggests substantial upside potential if their immunotherapy gains traction, making it a compelling investment thesis. Read the full article on Seeking Alpha
Articolo di analisi • Aug 11

Is iTeos Therapeutics (NASDAQ:ITOS) In A Good Position To Deliver On Growth Plans?

We can readily understand why investors are attracted to unprofitable companies. For example, although...
Seeking Alpha • Jul 09

iTeos Therapeutics: Rippling Waves Of TIGIT Pessimism

Summary iTeos Therapeutics is developing an anti-TIGIT molecule for various cancers, partnering with GSK and advancing to late-stage clinical studies. Their main clinical focus is belrestotug, aiming to differentiate from other anti-TIGIT approaches, with positive interim data readouts. Financially, ITOS has a strong balance sheet with significant cash reserves, but faces risks from unproven TIGIT targets and market valuation fluctuations. Read the full article on Seeking Alpha
Articolo di analisi • Jan 25

iTeos Therapeutics, Inc. (NASDAQ:ITOS) Looks Inexpensive But Perhaps Not Attractive Enough

With a price-to-sales (or "P/S") ratio of 5.3x iTeos Therapeutics, Inc. ( NASDAQ:ITOS ) may be sending very bullish...
Seeking Alpha • Jan 10

iTeos: Readouts From TIGIT And Adenosine Pathway Inhibitors Makes This A Must Watch

Summary Data readout from phase 2 GALAXIES Lung-201 study, using belrestotug in combination with dostarlimab to treat patients with 1st-line advanced/metastatic NSCLC, expected 2024. The global non-small cell lung cancer market is expected to reach $36.9 billion by 2031. Data readout from phase 2 TIGIT-006 study, using belrestotug in combination with dostarlimab for the treatment of patients with head and neck squamous cell carcinoma, expected 2024. The global head and neck cancer drugs market size is expected to surpass $3.9 billion by 2030. Read the full article on Seeking Alpha
Articolo di analisi • May 13

Industry Analysts Just Upgraded Their iTeos Therapeutics, Inc. (NASDAQ:ITOS) Revenue Forecasts By 16%

Celebrations may be in order for iTeos Therapeutics, Inc. ( NASDAQ:ITOS ) shareholders, with the analysts delivering a...
Articolo di analisi • Mar 21

Investors Give iTeos Therapeutics, Inc. (NASDAQ:ITOS) Shares A 25% Hiding

iTeos Therapeutics, Inc. ( NASDAQ:ITOS ) shareholders that were waiting for something to happen have been dealt a blow...
Articolo di analisi • Aug 12

The Consensus EPS Estimates For iTeos Therapeutics, Inc. (NASDAQ:ITOS) Just Fell Dramatically

The analysts covering iTeos Therapeutics, Inc. ( NASDAQ:ITOS ) delivered a dose of negativity to shareholders today, by...
Seeking Alpha • Aug 10

iTeos Therapeutics GAAP EPS of $0.16 misses by $1.04

iTeos Therapeutics press release (NASDAQ:ITOS): Q2 GAAP EPS of $0.16 misses by $1.04. The company’s cash and cash equivalent position was $791.9 million as of June 30, 2022, as compared to $302.9 million as of June 30, 2021. Cash balance is expected to provide the company runway into 2026..
Seeking Alpha • Jul 27

iTeos Therapeutics: Too Many Unknowns

Today, we put clinical stage oncology concern iTeos Therapeutics, Inc. in the spotlight for the first time. The company has two main oncology assets in development and a big partnership with GlaxoSmithKline. An investment analysis follows in the paragraphs below. Dandelions spring up where cities have been destroyed.”― Marty Rubin Today, we put iTeos Therapeutics, Inc. (ITOS) in the spotlight for the first time. This small cap oncology concern has a major partnership with a large drug maker and has two primary drug candidates under development. An analysis follows below. Seeking Alpha Company Overview iTeos Therapeutics, Inc. is a clinical-stage biopharmaceutical company headquartered just outside of Boston in Watertown, MA. The company also has a research center in Gosselies, Belgium. The firm is focused on the discovery and development of immuno-oncology therapeutics for patients. The stock currently trades around $25.00 a share and came public in the summer of 2020. It was founded in 2013. Its shares have an approximate market value of $900 million. iTeos Therapeutics has two clinical-stage product candidates, EOS-448 and Inupadenant, in development. Both target a key mechanism that inhibits an effective antitumor immune response. March Company Presentation EOS-448: This is an anti-TIGIT human immunoglobulin G1, or IgG1, antibody that the company is developing to inhibit the immunosuppressive activity of TIGIT. TIGIT is a cell surface receptor expressed on multiple immune cells, including CD8+ T cells, natural killer, or NK, cells and T regulatory cells. EOS-448 binds with high affinity to TIGIT, thereby breaking the immunosuppressive interaction between TIGIT and its ligands. It can also activate FcγR on macrophages, dendritic cells and NK cells in the tumor microenvironment. March Company Presentation According to the company website: This activation of these cells augments the anti-tumor immune response but also triggers Antibody Dependent Cellular Cytotoxicity or ADCC response to those cells which expressed the highest levels of TIGIT, the Tregs." EOS-448 is being developed jointly with GlaxoSmithKline (GSK) under a collaboration arrangement reached last Spring (see below section for details). This is the largest of several developmental partnerships the company has sealed. iTeos has initiated several 1b/2a studies around EOS-448 involving four combo therapies and targeting three indications. March Company Presentation It should be noted that Glaxo and iTeos are working together to evaluate how best to proceed with additional clinical development of EOS-448 in light of the recent release regarding the Roche (RHHBY) SKYSCRAPER-01 study which came out in Mid-May and did not meet its primary endpoint. This trial involved another anti-TIGIT program. Enrollment is also underway in a clinical trial evaluating EOS-448 as both a monotherapy and in combination with Bristol Myers Squibb’s (BMY) iberdomide in patients with multiple myeloma, one of several efforts outside the joint development program with Glaxo. The second compound in development is Inupadenant. This compound is designed to inhibit the ATP-adenosine pathway by specifically targeting A2AR. This is the primary adenosine receptor on immune cells with a high affinity for adenosine. This pathway is recognized as a key pathway that modulates immune responses in pathological conditions. March Company Presentation This candidate is in a much earlier stage of development. The company is in the process of initiating a randomized Phase 2 trial mid-year in metastatic non-small cell lung cancer (mNSCLC) to evaluate the combination of inupadenant with chemotherapy compared to standard of care. iTeos is also enrolling patients in a Phase 2a trial evaluating inupadenant in combination with pembrolizumab in PD-1 resistant melanoma. Analyst Commentary & Balance Sheet Four analyst firms including JPMorgan and Wedbush have reissued Buy ratings on the stock since Mid-May. Price targets proffered range from $34 to $52 a share.
Articolo di analisi • May 11

News Flash: Analysts Just Made A Captivating Upgrade To Their iTeos Therapeutics, Inc. (NASDAQ:ITOS) Forecasts

Celebrations may be in order for iTeos Therapeutics, Inc. ( NASDAQ:ITOS ) shareholders, with the analysts delivering a...
Articolo di analisi • Nov 25

Rainbows and Unicorns: iTeos Therapeutics, Inc. (NASDAQ:ITOS) Analysts Just Became A Lot More Optimistic

Celebrations may be in order for iTeos Therapeutics, Inc. ( NASDAQ:ITOS ) shareholders, with the analysts delivering a...

Analisi delle retribuzioni degli amministratori delegati

Come è cambiata la remunerazione di Michel Detheux rispetto agli utili di iTeos Therapeutics?
DataCompenso totaleStipendioUtili della società
Jun 30 2025n/an/a

-US$202m

Mar 31 2025n/an/a

-US$131m

Dec 31 2024US$6mUS$629k

-US$134m

Sep 30 2024n/an/a

-US$121m

Jun 30 2024n/an/a

-US$108m

Mar 31 2024n/an/a

-US$135m

Dec 31 2023US$6mUS$579k

-US$113m

Sep 30 2023n/an/a

-US$62m

Jun 30 2023n/an/a

-US$28m

Mar 31 2023n/an/a

US$12m

Dec 31 2022US$11mUS$556k

US$97m

Sep 30 2022n/an/a

US$261m

Jun 30 2022n/an/a

US$330m

Mar 31 2022n/an/a

US$298m

Dec 31 2021US$6mUS$525k

US$215m

Sep 30 2021n/an/a

US$15m

Jun 30 2021n/an/a

-US$67m

Mar 31 2021n/an/a

-US$50m

Dec 31 2020US$17mUS$463k

-US$43m

Sep 30 2020n/an/a

-US$35m

Jun 30 2020n/an/a

-US$31m

Mar 31 2020n/an/a

-US$28m

Dec 31 2019US$2mUS$460k

-US$27m

Compensazione vs Mercato: La retribuzione totale di Michel ($USD 6.09M ) è superiore alla media delle aziende di dimensioni simili nel mercato US ($USD 2.59M ).

Compensazione vs guadagni: La retribuzione di Michel è aumentata nonostante l'azienda non sia redditizia.

AMMINISTRATORE DELEGATO

Michel Detheux (59 yo)

14yrs
Mandato
US$6,085,657
Compensazione

Dr. Michel Detheux, Ph D, has been the Director of Vor Biopharma Inc. since July 16, 2025. He is Chairman of the Board at InnoSkel.He serves as an Independent Chairman at Ona Therapeutics, S.L. since Dece...

Gruppo dirigente

NomePosizioneMandatoCompensazioneProprietà
Michel Detheux
President14yrsUS$6.09m0.31%
$ 1.4m
Matthew Call
Chief Operating Officer6yrsUS$2.62m0.21%
$ 953.1k
David Feltquate
Chief Medical Officer1yrUS$5.35m0%
$ 0
Matthew Gall
Chief Financial Officer5.2yrsUS$2.72m0.055%
$ 247.9k
Yvonne McGrath
Chief Scientific Officer3.6yrsNessun datoNessun dato
Adi Osovsky
Executive Vice President of Legal2.6yrsNessun datoNessun dato
Philippe Brantegem
Chief People Officer5.6yrsNessun datoNessun dato
5.2yrs
Durata media
51.5yo
Età media

Gestione esperta: Il team dirigenziale di ITOS è esperto e expertise (durata media dell'incarico 5.2 anni).

Membri del Consiglio di amministrazione

NomePosizioneMandatoCompensazioneProprietà
Michel Detheux
President13.6yrsUS$6.09m0.31%
$ 1.4m
Ann Rhoads
Independent Director5.2yrsUS$345.57k0%
$ 0
David Hallal
Independent Chairman of the Board7.2yrsUS$442.82k0%
$ 0
Matthew Vander Heiden
Member of Scientific Advisory Boardno dataNessun datoNessun dato
Jill DeSimone
Independent Director1.4yrsUS$686.27k0%
$ 0
Tony W. Ho
Independent Director4.3yrsUS$332.76k0%
$ 0
Robert Iannone
Independent Director4.3yrsUS$341.26k0%
$ 0
David Lee
Independent Director1.7yrsUS$320.07k0%
$ 0
Gordon Freeman
Chairman of Scientific Advisory Boardno dataNessun datoNessun dato
Benoit Van den Eynde
Member of Scientific Advisory Boardno dataNessun datoNessun dato
Florent Ginhoux
Member of Scientific Advisory Boardno dataNessun datoNessun dato
Roberta Zappasodi
Member of Scientific Advisory Boardno dataNessun datoNessun dato
4.3yrs
Durata media
59yo
Età media

Consiglio di amministrazione esperto: I membri del consiglio di amministrazione di ITOS sono considerati esperti (durata media dell'incarico 4.3 anni).

Analisi aziendale e situazione dei dati finanziari

DatiUltimo aggiornamento (ora UTC)
Analisi dell'azienda2025/08/30 09:04
Prezzo dell'azione a fine giornata2025/08/28 00:00
Utili2025/06/30
Utili annuali2024/12/31

Fonti dei dati

I dati utilizzati nella nostra analisi aziendale provengono da S&P Global Market Intelligence LLC. I seguenti dati sono utilizzati nel nostro modello di analisi per generare questo report. I dati sono normalizzati, il che può comportare un ritardo nella disponibilità della fonte.

PacchettoDatiTempisticaEsempio Fonte USA *
Dati finanziari della società10 anni
  • Conto economico
  • Rendiconto finanziario
  • Bilancio
Stime di consenso degli analisti+3 anni
  • Previsioni finanziarie
  • Obiettivi di prezzo degli analisti
Prezzi di mercato30 anni
  • Prezzi delle azioni
  • Dividendi, scissioni e azioni
Proprietà10 anni
  • Top azionisti
  • Insider trading
Gestione10 anni
  • Team di leadership
  • Consiglio di amministrazione
Sviluppi principali10 anni
  • Annunci aziendali

* Esempio per i titoli statunitensi, per i titoli non statunitensi si utilizzano forme e fonti normative equivalenti.

Se non specificato, tutti i dati finanziari si basano su un periodo annuale ma vengono aggiornati trimestralmente. Si tratta dei cosiddetti dati TTM (Trailing Twelve Month) o LTM (Last Twelve Month). Per saperne di più.

Modello di analisi e Snowflake

I dettagli del modello di analisi utilizzato per generare questo report sono disponibili sulla nostra pagina Github; abbiamo anche guide su come utilizzare i nostri report e tutorial su Youtube.

Scoprite il team di livello mondiale che ha progettato e realizzato il modello di analisi Simply Wall St.

Metriche di settore e industriali

Le nostre metriche di settore e di sezione sono calcolate ogni 6 ore da Simply Wall St; i dettagli del nostro processo sono disponibili su Github.

Fonti analitiche

iTeos Therapeutics, Inc. è coperta da 3 analisti. 5 di questi analisti ha fornito le stime di fatturato o di utile utilizzate come input per il nostro report. Le stime degli analisti vengono aggiornate nel corso della giornata.

AnalistaIstituzione
Michael UlzBaird
Derek ArchilaWells Fargo Securities, LLC
Eva Fortea-VerdejoWells Fargo Securities, LLC