Vertex Pharmaceuticals Incorporated

NasdaqGS:VRTX Rapport sur les actions

Capitalisation boursière : US$126.5b

Vertex Pharmaceuticals Gestion

Gestion contrôle des critères 3/4

Le PDG Vertex Pharmaceuticals est Reshma Kewalramani, nommé en Apr2020, a un mandat de 6.25 ans. La rémunération annuelle totale est $ 21.14M, composée du salaire de 7.6% et des bonus 92.4%, y compris les actions et options de la société. détient directement 0.039% des actions de la société, d'une valeur de $ 48.98M. La durée moyenne de mandat de l'équipe de direction et du conseil d'administration est respectivement 6.5 ans et 6.9 ans.

Informations clés

Reshma Kewalramani

Directeur général

US$21.1m

Rémunération totale

Pourcentage du salaire du PDG7.57%
Durée du mandat du directeur général6.3yrs
Propriété du PDG0.04%
Durée moyenne d'occupation des postes de direction6.5yrs
Durée moyenne du mandat des membres du conseil d'administration6.9yrs

Mises à jour récentes de la gestion

Recent updates

Seeking Alpha Jun 30

Vertex Pharmaceuticals Has One Of The Widest And Most Durable Moats In Biotech

Summary Vertex Pharmaceuticals Incorporated maintains a dominant, monopoly position in cystic fibrosis, driving highly predictable, recurring revenue and justifying its valuation premium. VRTX is leveraging its CF cash flows to expand into pain, hematology, and renal franchises, with promising catalysts in each area, notably Pove for IgAN. Non-CF franchises are gaining traction, with Journavx and Casgevy contributing to revenue growth; renal (Pove) is positioned to become a major driver post-2027. I maintain a Buy rating on VRTX, citing its wide moat, robust pipeline, pristine balance sheet, and clear sightlines to long-term market-beating returns. Read the full article on Seeking Alpha
Mise à jour du récit Jun 17

VRTX: Kidney Franchise And Pipeline Expansion Will Drive Future Stock Upside

Vertex Pharmaceuticals' latest narrative update reflects a modest recalibration in analyst price targets, with figures such as Truist's move to $542 and Wells Fargo's lift to $550 framed around analysts' view that the emerging kidney franchise can grow into blockbuster assets and broaden the company's portfolio. Analyst Commentary Recent Street research on Vertex Pharmaceuticals highlights a generally constructive tone, with bullish analysts pointing to the expanding kidney franchise and a series of upward price target revisions as key supports for the stock's valuation and growth narrative.
Mise à jour du récit Jun 03

VRTX: Kidney Franchise Progress Will Drive Future Upside Beyond CF

Analysts have nudged their average price target on Vertex Pharmaceuticals higher by a few dollars to around the mid $500s to low $600s, citing positive Phase 3 RAINIER data and the perceived de-risking of the emerging kidney franchise as key reasons for the change. Analyst Commentary Bullish analysts are broadly aligning around a more constructive view on Vertex Pharmaceuticals following the RAINIER readout, with several pointing to the kidney franchise as a key driver for the stock story alongside the established cystic fibrosis business.
Mise à jour du récit May 19

VRTX: CF Franchise And Nephrology Pipeline Will Shape Balanced Future Risk Profile

Analysts have inched their fair value target for Vertex Pharmaceuticals higher to about $414 per share. This reflects updated assumptions that pair slightly more conservative revenue growth expectations with higher projected profit margins and a lower anticipated future P/E multiple.
Mise à jour du récit May 05

VRTX: CF Base And Nephrology Expansion Will Define Balanced Future Risk Profile

Analysts have inched their average price target for Vertex Pharmaceuticals higher by a few dollars, citing stronger confidence in povetacicept after positive Phase 3 RAINIER data in IgA nephropathy and a broader nephrology pipeline thesis, while keeping valuation assumptions such as P/E and discount rate broadly consistent. Analyst Commentary Recent Street research on Vertex Pharmaceuticals has centered on povetacicept and the nephrology pipeline, with several major firms adjusting their models after the Phase 3 RAINIER interim readout in IgA nephropathy and following Q4 results.
Mise à jour du récit Apr 20

VRTX: CF Franchise And Kidney Pipeline Will Shape Balanced Risk Profile

Vertex Pharmaceuticals' fair value estimate has shifted from $403.80 to $412.49 as analysts refresh models following multiple price target increases tied to positive Phase 3 povetacicept data and a reassessment of the company's nephrology pipeline potential. Analyst Commentary Recent Street research on Vertex Pharmaceuticals has leaned constructive overall, with several firms lifting price targets following the Phase 3 RAINIER interim readout for povetacicept and updating models around the nephrology pipeline.
Mise à jour du récit Apr 05

VRTX: Renal Franchise Progress And CF Leadership Will Drive Future Upside

Vertex Pharmaceuticals' analyst fair value estimate has shifted to $641 from $604. This reflects analysts' updated views on the company's diversified pipeline following positive Phase 3 povetacicept data in IgA nephropathy and a series of higher Street price targets.
Mise à jour du récit Mar 22

VRTX: Renal Trial Success And Nephrology Pipeline Will Drive Next Phase

Vertex Pharmaceuticals' analyst fair value estimate has moved from $504.04 to $547.72. Analysts point to higher modeled revenue growth, slightly stronger profit margins, a richer future P/E assumption, and a wave of Street price target hikes tied to positive povetacicept Phase 3 RAINIER data and the growing nephrology pipeline.
Mise à jour du récit Mar 06

VRTX: CF Dependence Will Heighten Risk Around Upcoming Renal Readouts

Analysts have nudged their target on Vertex Pharmaceuticals higher, with our fair value estimate moving from $401.30 to $403.80. This reflects updated Q4 results, slightly adjusted revenue growth and margin assumptions, and ongoing confidence in the broader pipeline, as seen in a series of recent price target increases across the Street.
Mise à jour du récit Feb 20

VRTX: CF Reliance Will Expose Renal Pipeline Execution Risks

Vertex Pharmaceuticals' updated analyst price target reflects an increase of $23.78 to $401.30, as analysts incorporate refreshed Q4 outcomes, pipeline commentary on programs like povetacicept and IgAN, and modest adjustments to assumptions for revenue growth, profit margin, and future P/E. Analyst Commentary Street research around Vertex Pharmaceuticals has been active following the latest Q4 update, with several firms revisiting their models, refreshing pipeline assumptions, and revising price targets.
Mise à jour du récit Feb 06

VRTX: CF Dependence And Pipeline Execution Risks Will Test Bullish Repricing

Analysts have raised their fair value estimate for Vertex Pharmaceuticals by about US$33 to approximately US$378, citing a series of recent rating upgrades and higher price targets linked to its cystic fibrosis franchise and late-stage pipeline potential. Analyst Commentary Recent research on Vertex Pharmaceuticals has been dominated by upgrades and higher price targets, with several firms shifting to more positive ratings and highlighting the cystic fibrosis portfolio and late stage pipeline as key supports for the updated fair value assessments.
Mise à jour du récit Jan 23

VRTX: CF Cash Flows And Renal Data Will Shape Balanced Next Phase

Analysts have nudged their fair value estimate for Vertex Pharmaceuticals higher to about $504, citing a slightly richer assumed future P/E multiple and modestly stronger revenue growth expectations, even as they factor in a lower profit margin and a slightly higher discount rate. Analyst Commentary Recent Street research on Vertex Pharmaceuticals has turned more constructive, with several firms shifting to more positive ratings and setting price targets above the current fair value estimate.
Mise à jour du récit Jan 09

VRTX: CF Durability And Kidney Pipeline Data Will Define Next Phase

Analysts have lifted their Vertex Pharmaceuticals fair value estimate by about US$11 to US$496.16, reflecting updated assumptions on revenue growth, margins and future P/E, as recent research highlights confidence in the durability of its cystic fibrosis franchise and potential upside from its broader pipeline. Analyst Commentary Recent Street research around Vertex Pharmaceuticals points to a generally constructive view, with most commentary focusing on the durability of the cystic fibrosis franchise, the breadth of the pipeline and how these factors feed into valuation targets and rating changes.
Mise à jour du récit Dec 18

VRTX: Cystic Fibrosis And Gene Editing Advances Will Drive Upside Potential

Narrative Update The analyst price target for Vertex Pharmaceuticals has been modestly reduced to about $604 from roughly $616 as analysts factor in a slightly higher discount rate and marginally slower revenue growth, partially offset by improved profitability and a lower assumed future P/E multiple. Analyst Commentary Bullish analysts remain broadly constructive on Vertex Pharmaceuticals, emphasizing durable execution in cystic fibrosis, a deep late stage pipeline, and multiple emerging revenue drivers that, in their view, support premium valuation multiples despite modest target tweaks.
Mise à jour du récit Dec 04

VRTX: Kidney Pipeline And Gene Editing Will Shape Next Phase

The analyst price target for Vertex Pharmaceuticals has been nudged higher to about $485 from roughly $480 as analysts point to a healthier long term earnings profile supported by ongoing strength in the cystic fibrosis franchise, measured diversification investments, and an increasingly innovation focused large cap biopharma setup. Analyst Commentary Recent research updates on Vertex Pharmaceuticals highlight a broadly constructive stance on the name, with most price target changes and rating initiations reinforcing confidence in the company’s growth algorithm and innovation pipeline, even as some voices flag valuation and execution constraints as the franchise matures.
Article d’analyse Nov 11

Vertex Pharmaceuticals' (NASDAQ:VRTX) Performance Is Even Better Than Its Earnings Suggest

Even though Vertex Pharmaceuticals Incorporated's ( NASDAQ:VRTX ) recent earnings release was robust, the market didn't...
Article d’analyse Sep 19

Vertex Pharmaceuticals Incorporated's (NASDAQ:VRTX) Popularity With Investors Is Under Threat From Overpricing

It's not a stretch to say that Vertex Pharmaceuticals Incorporated's ( NASDAQ:VRTX ) price-to-sales (or "P/S") ratio of...
Mise à jour du récit Sep 04

Gene Editing And New Therapies Will Transform Global Healthcare

Analysts maintain a cautious-but-constructive stance on Vertex Pharmaceuticals, citing strong CF performance and resilient topline results offset by pipeline setbacks and future revenue concentration risks, with the consensus price target unchanged at $481.04. Analyst Commentary Bullish analysts highlight Vertex’s continued strong execution track record, robust base cystic fibrosis (CF) business, solid Q2 results with topline beats, and a positive long-term growth outlook beyond near-term setbacks.
Nouveau récit Apr 08

New ALYFTREK And JOURNAVX Will Expand Patient Access

Vertex is set to drive revenue growth by expanding its drug portfolio, notably with ALYFTREK and JOURNAVX, targeting new patient demographics.
Seeking Alpha Apr 06

Vertex Pharmaceuticals: A Look At Their Pain Therapy Program

Summary Vertex Pharmaceuticals is diversifying from its cystic fibrosis dominance into pain, sickle cell disease, beta thalassemia, and type 1 diabetes, with approved products in each area. Suzetrigine (Journavx) shows promise as a non-addictive pain treatment, offering systemic relief without opioid-related side effects, but faces Tier 3 insurance hurdles. Financially strong with a market cap of $124bn and $11.2bn in cash, Vertex's pain program needs further trials to overcome high placebo effects in Lumbosacral Radiculopathy. While Vertex's diversification is commendable, investors should wait for a few quarters of revenue from the pain program before making investment decisions. Read the full article on Seeking Alpha
Seeking Alpha Mar 06

Vertex Pharmaceuticals: Company Passes My Health Check With Flying Colors, Upholding Buy Rating

Summary Vertex Pharmaceuticals Incorporated's stock has shown resilience, recovering from dips and maintaining a strong long-term growth trajectory, driven by its robust CF franchise and new product approvals. The company’s 2024 performance was solid, with TRIKAFTA/KAFTRIO generating >$10bn revenues, and 2025 guidance suggesting continued growth despite some challenges. Vertex's diversification efforts include the approval of pain therapy JOURNAVX and gene therapy Casgevy, with potential multi-billion-dollar revenue contributions from these and other pipeline drugs. Despite potential headwinds, Vertex's strong cash position and promising pipeline support a “Buy” rating for VRTX stock, with expectations of further long-term growth and multiple blockbuster drugs. Read the full article on Seeking Alpha
Seeking Alpha Jan 31

Vertex Pharma Stock Surges After FDA Approves Non-Opioid Pain Drug

Summary JOURNAVX, a non-opioid analgesic, shows significant promise in treating pain with a superior safety profile, addressing a critical unmet need compared to opioids with FDA approval just announced. Vertex Pharmaceuticals continues to execute its commercialization of three new drugs, JOURNAVX, CASGEVY, and ALYFTREK. Two of which have been approved by the FDA since December. Vertex's valuation appears high due to recent expenses, but analysts expect substantial earnings growth in 2025 as acquisition and clinical expenses subside. With multiple ongoing clinical trials and a robust pipeline, Vertex is poised to exceed conservative analyst revenue projections, making the stock a STRONG BUY with a 12-month price of $550/share. Read the full article on Seeking Alpha
Seeking Alpha Jan 14

Vertex Therapeutics: The Pain Comes With The Territory For Suzetrigine

Summary I last wrote here several months ago about the sodium channel (NaV1.8) inhibitor VX-548 (now known as suzetrigine), which is under investigation as a pain relief medication. In that earlier post on this drug, it had shown some very interesting (though modest) activity in post-surgical patients, albeit with some questions about its efficacy relative to Vicodin standard-of-care. Vertex has been running a number of trials because if there’s one thing that we can take away from the failed drug development projects of the past, it’s that there are many kinds of pain. Just before the holiday break, Vertex reported on another of these trials with suzetrigine in sciatica patients. Read the full article on Seeking Alpha
Seeking Alpha Dec 31

Vertex Pharmaceuticals: Jim Cramer Fires A Warning Shot But I Remain Invested

Summary Vertex Pharmaceuticals' suzetrigine showed lackluster Phase II results, but I still see potential in the non-addictive pain management market given the opioid crisis. Vertex's dominance in the cystic fibrosis (CF) drug market, including recent FDA approval for Alyftrek, ensures strong revenue and market expansion. The company's pipeline diversification, targeting diabetic peripheral neuropathy, IgA nephropathy, type 1 diabetes, and gene editing, promises long-term growth. Despite high valuation risks, VRTX's innovative CF treatments and diversified pipeline make it a compelling long-term investment opportunity. Read the full article on Seeking Alpha

Analyse de la rémunération des PDG

Comment la rémunération de Reshma Kewalramani a-t-elle évolué par rapport aux bénéfices de Vertex Pharmaceuticals?
DateRémunération totaleSalaireBénéfices de l'entreprise
Mar 31 2026n/an/a

US$4b

Dec 31 2025US$21mUS$2m

US$4b

Sep 30 2025n/an/a

US$4b

Jun 30 2025n/an/a

US$4b

Mar 31 2025n/an/a

-US$989m

Dec 31 2024US$22mUS$2m

-US$536m

Sep 30 2024n/an/a

-US$480m

Jun 30 2024n/an/a

-US$490m

Mar 31 2024n/an/a

US$4b

Dec 31 2023US$21mUS$2m

US$4b

Sep 30 2023n/an/a

US$3b

Jun 30 2023n/an/a

US$3b

Mar 31 2023n/an/a

US$3b

Dec 31 2022US$16mUS$1m

US$3b

Sep 30 2022n/an/a

US$3b

Jun 30 2022n/an/a

US$3b

Mar 31 2022n/an/a

US$2b

Dec 31 2021US$15mUS$1m

US$2b

Sep 30 2021n/an/a

US$2b

Jun 30 2021n/an/a

US$2b

Mar 31 2021n/an/a

US$3b

Dec 31 2020US$9mUS$1m

US$3b

Sep 30 2020n/an/a

US$3b

Jun 30 2020n/an/a

US$2b

Mar 31 2020n/an/a

US$2b

Dec 31 2019US$7mUS$702k

US$1b

Rémunération vs marché: La rémunération totale de Reshma ($USD 21.14M ) est supérieure à la moyenne des entreprises de taille similaire sur le marché US ($USD 14.63M ).

Rémunération et revenus: La rémunération de Reshma a été cohérente avec les performances de l'entreprise au cours de l'année écoulée.


PDG

Reshma Kewalramani (53 yo)

6.3yrs
Titularisation
US$21,144,261
Compensation

Dr. Reshma Kewalramani, M.D., FASN, was Director at Year Up Inc. since September 2023. She had been an Independent Director of Ginkgo Bioworks Holdings, Inc. (formerly known as Ginkgo Bioworks, Inc.) since...


Équipe de direction

NomPositionTitularisationCompensationPropriété
Jeffrey Leiden
Executive Chairman17yrspas de données0.014%
$ 17.6m
Reshma Kewalramani
CEO, President & Director6.3yrsUS$21.14m0.039%
$ 49.0m
Charles Wagner
Executive VP7.3yrsUS$8.24m0.011%
$ 13.8m
Amit Sachdev
Executive VP & Chief Patient and External Affairs Officer19yrsUS$6.78m0.026%
$ 32.8m
Ourania Tatsis
Executive VP and Chief Regulatory & Quality Officer8.8yrsUS$6.97m0.018%
$ 22.6m
Carmen Bozic
Executive VP of Global Medicines Development & Medical Affairs and Chief Medical Officer6.8yrsUS$6.65m0.0060%
$ 7.6m
Kristen Ambrose
Senior VP & Chief Accounting Officer5.2yrspas de données0.0026%
$ 3.3m
Mark Bunnage
Executive VP & Chief Scientific Officerless than a yearpas de données0.0029%
$ 3.6m
Susie Lisa
Senior Vice President of Investor Relations3.8yrspas de donnéespas de données
Joy Liu
EVP, Chief Legal Officer & Corporate Secretaryless than a yearpas de données0.0075%
$ 9.5m
Nina Devlin
Senior VP & Chief Communications Officer7.5yrspas de donnéespas de données
Stephanie Franklin
Senior VP & Chief Human Resources Officer8.9yrspas de donnéespas de données
6.5yrs
Durée moyenne de l'emploi
57yo
Âge moyen

Gestion expérimentée: L'équipe dirigeante de VRTX est chevronnée et expérimentée (6.5 années d'ancienneté moyenne).


Membres du conseil d'administration

NomPositionTitularisationCompensationPropriété
Jeffrey Leiden
Executive Chairman17yrspas de données0.014%
$ 17.6m
Reshma Kewalramani
CEO, President & Director6.4yrsUS$21.14m0.039%
$ 49.0m
Bruce Sachs
Lead Independent Director28.5yrsUS$615.13k0.018%
$ 22.4m
Alan Garber
Independent Director9.1yrsUS$545.25k0.0027%
$ 3.4m
Lloyd Carney
Independent Director7.4yrsUS$565.36k0.0022%
$ 2.7m
Sangeeta Bhatia
Independent Director11.1yrsUS$560.36k0.0016%
$ 2.0m
Michel Lagarde
Independent Director2.8yrsUS$540.13k0.00045%
$ 569.3k
Diana McKenzie
Independent Director6.1yrsUS$552.86k0.00065%
$ 822.3k
Nancy Thornberry
Independent Director2.6yrsUS$528.25k0.00064%
$ 809.6k
Jennifer Schneider
Independent Director2.2yrsUS$537.86k0.00036%
$ 455.4k
6.9yrs
Durée moyenne de l'emploi
62.5yo
Âge moyen

Conseil d'administration expérimenté: Les membres du conseil d'administration de VRTX sont considérés comme expérimentés (ancienneté moyenne 6.9 ans).


Analyse de l'entreprise et données financières

DonnéesDernière mise à jour (heure UTC)
Analyse de l'entreprise2026/07/09 21:51
Cours de l'action en fin de journée2026/07/09 00:00
Les revenus2026/03/31
Revenus annuels2025/12/31

Sources de données

Les données utilisées dans notre analyse de l'entreprise proviennent de S&P Global Market Intelligence LLC. Les données suivantes sont utilisées dans notre modèle d'analyse pour générer ce rapport. Les données sont normalisées, ce qui peut entraîner un délai avant que la source ne soit disponible.

PaquetDonnéesCadre temporelExemple de source américaine *
Finances de l'entreprise10 ans
  • Compte de résultat
  • Tableau des flux de trésorerie
  • Bilan
Estimations consensuelles des analystes+3 ans
  • Prévisions financières
  • Objectifs de prix des analystes
Prix du marché30 ans
  • Cours des actions
  • Dividendes, scissions et actions
Propriété10 ans
  • Actionnaires principaux
  • Délits d'initiés
Gestion10 ans
  • L'équipe dirigeante
  • Conseil d'administration
Principaux développements10 ans
  • Annonces de l'entreprise

* Exemple pour les titres américains ; pour les titres non américains, des formulaires réglementaires et des sources équivalentes sont utilisés.

Sauf indication contraire, toutes les données financières sont basées sur une période annuelle mais mises à jour trimestriellement. C'est ce qu'on appelle les données des douze derniers mois (TTM) ou des douze derniers mois (LTM). En savoir plus.

Modèle d'analyse et flocon de neige

Les détails du modèle d'analyse utilisé pour générer ce rapport sont disponibles sur notre page Github, nous proposons également des guides pour apprendre à utiliser nos rapports et des tutoriels sur YouTube.

Découvrez l'équipe de classe mondiale qui a conçu et construit le modèle d'analyse Simply Wall St.

Indicateurs de l'industrie et du secteur

Nos indicateurs de secteur et de section sont calculés toutes les 6 heures par Simply Wall St. Les détails de notre processus sont disponibles sur Github.

Sources des analystes

Vertex Pharmaceuticals Incorporated est couverte par 58 analystes. 29 de ces analystes ont soumis les estimations de revenus ou de bénéfices utilisées comme données d'entrée dans notre rapport. Les soumissions des analystes sont mises à jour tout au long de la journée.

AnalysteInstitution
Jasper HellwegArgus Research Company
Brian SkorneyBaird
Eliana MerleBarclays