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Terns Pharmaceuticals, Inc.NasdaqGS:TERN Rapport sur les actions

Capitalisation boursière US$6.1b
Prix de l'action
US$52.95
US$98.57
46.3% sous-évalué décote intrinsèque
1Y1,641.8%
7D0.04%
Valeur du portefeuille
​
Voir

Terns Pharmaceuticals, Inc.

NasdaqGS:TERN Rapport sur les actions

Capitalisation boursière : US$6.1b

This company has been acquired

The company may no longer be operating, as it has been acquired. Find out why through their latest events.

Terns Pharmaceuticals (TERN) Aperçu de l'action

Terns Pharmaceuticals, Inc. est une société biopharmaceutique au stade clinique qui développe des produits candidats à base de petites molécules pour le traitement de l'oncologie et de l'obésité. Plus de détails

TERN analyse fondamentale
Score flocon de neige
Évaluation1/6
Croissance future0/6
Performances passées0/6
Santé financière6/6
Dividendes0/6

Analyse des risques

Réalise moins d'un million de dollars de revenus ( $0 )

Les actionnaires ont été considérablement dilués au cours de l'année écoulée

Les bénéfices devraient diminuer en moyenne de 5.7% par an au cours des 3 prochaines années

Actuellement non rentable et ne devrait pas le devenir au cours des 3 prochaines années


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Terns Pharmaceuticals, Inc. Concurrents

Historique des prix et performances

Résumé des hausses, des baisses et des variations du cours de l'action pour la période du 1er janvier au 31 décembre 2009 Terns Pharmaceuticals
Historique des cours de bourse
Prix actuel de l'actionUS$52.95
Plus haut sur 52 semainesUS$53.19
Plus bas sur 52 semainesUS$2.66
Bêta-0.38
Variation sur 1 mois0.55%
Variation sur 3 mois40.19%
Variation sur 1 an1,641.78%
Variation sur 3 ans318.25%
Variation sur 5 ans232.81%
Évolution depuis l'introduction en bourse187.93%

Nouvelles et mises à jour récentes

Recent updates

Seeking Alpha • Mar 25

Merck's Deal For Terns And Its Stellar CML Drug Candidate Looks Like Good Business

Summary Merck & Co., Inc. acquires Terns Pharmaceuticals, Inc. for $53/share, valuing the deal at ~$6.7bn, to secure TERN-701's blockbuster CML potential. TERN-701's Phase 1 data show a 75% MMR rate at 24 weeks, significantly outperforming current standard-of-care therapies like Novartis' Scemblix. MRK seeks to offset looming Keytruda patent expiry by adding high-potential oncology assets, with TERN-701 positioned as a future growth driver. While the acquisition introduces execution and regulatory risks, MRK's diversified pipeline and strategic M&A activity support a long-term bullish outlook. Read the full article on Seeking Alpha
Article d'analyse • Sep 19

Terns Pharmaceuticals (NASDAQ:TERN) Is In A Good Position To Deliver On Growth Plans

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although Amazon.com...
Seeking Alpha • Feb 08

Terns Pharma: I Don't See The Positioning

Summary Terns Pharmaceuticals' lead molecules, TERN-701 and TERN-601, face stiff competition from established and more effective treatments in CML and obesity markets. TERN-701's advantage of food-independent dosing may not be sufficient to challenge entrenched CML treatments like Asciminib. TERN-601 showed modest weight loss results but falls short compared to competitors like semaglutide and Amgen's MariTide. With a market cap of $383mn and trading at cash, Terns' strategy of developing copycat molecules appears unpromising; I recommend avoiding this stock. Read the full article on Seeking Alpha
Seeking Alpha • Oct 21

Terns Pharmaceuticals: Another Potential GLP-1 Entrant

Summary Terns Pharmaceuticals' stock has risen somewhat due to some optimism around its early-stage clinical programs, particularly TERN-601 for obesity and TERN-701 for CML. TERN-601 showed promising Phase 1 results, leading to a capital raise extending the cash runway to 2028, with Phase 2 trials expected in 2025. TERN-701, targeting CML, has interim Phase 1 data expected in December 2024, with potential to address unmet needs in the $5 billion CML market. An updated analysis around Terns Pharmaceuticals follows in the paragraphs below. Read the full article on Seeking Alpha
Seeking Alpha • Sep 25

Terns Pharmaceuticals: Obesity Advancement Continues With Other Q1 2025 Program Catalyst

Summary Terns Pharmaceuticals is developing TERN-601, an oral GLP-1R agonist, which showed a placebo-adjusted weight loss of 4.9% in a phase 1 trial for obesity treatment. The company plans to initiate a phase 2 study for TERN-601 in 2025, creating a significant catalyst opportunity for investors. The company is also developing TERN-701 for chronic myeloid leukemia, with interim phase 1 data expected in December 2024, offering another investment opportunity. The global anti-obesity drugs market is expected to reach $100 billion by 2030. Read the full article on Seeking Alpha
Seeking Alpha • Sep 10

Terns Pharmaceuticals: Weight Loss Drug TERN-601 Is Competitive

Summary Terns Pharmaceuticals' TERN-601 shows impressive weight loss results in a phase 1 study, positioning TERN competitively in the obesity drug market. The commercial viability of TERN-601's manufacturing scalability could be an advantage over certain competitors like Novo Nordisk's Rybelsus. TERN has sufficient funds to support operations into 2026, and a recent $125M public offering could allow it to go further. Read the full article on Seeking Alpha
Seeking Alpha • Sep 20

Terns Pharmaceuticals: The Easy Money Has Been Made

Summary Shares of biotech concern Terns Pharmaceuticals are up some 150% after consummating a secondary offering at $2.42 a share, announced on August 12, 2022. Despite the bump, shares of Terns Pharmaceuticals are still down significantly from their IPO pricing back in January 2021, as the once solely NASH-focused company is making a foray into leukemia. With NASH, obesity, and oncology assets but few near-terms catalysts, the significant beneficial owner buying of Terns Pharmaceuticals on the secondary merited a deeper dive. A full investment analysis follows in the paragraphs below. Don’t fear what other people can do. Fear most what you could have done, but didn’t.” ― Craig D. Lounsbrough Today, we take our first look at a small developmental concern. The company has had a significant change of focus, recently did a capital raise, and has several "shots on goal." An analysis follows below. Seeking Alpha Company Overview: Terns Pharmaceuticals, Inc. (TERN) is a Foster City, California-based early clinical-stage biopharmaceutical concern focused on the development of small-molecule therapeutics for indications with high unmet needs. The company currently has four candidates in the clinic undergoing evaluation in the treatment of two diseases, and a fifth asset that should enter the clinic in 2023. Terns was formed in 2016 and backed by Eli Lilly (LLY), which out-licensed its non-alcoholic steatohepatitis [NASH] portfolio to the then-startup, along with a Series A investment of $30 million in 2018. The company went public in February 2021, raising net proceeds of $132.9 million at $17 per share. This somewhat thinly traded stock is currently selling at just over six bucks a sharer, translating to a market cap of just under $350 million, after giving effect to 14.63 million pre-funded warrants. Pipeline: After releasing disappointing data from a Phase 1 NASH trial in March 2022, Terns is now leading with a cancer therapy in its corporate presentations and SEC filings. August Company Presentation TERN-701. The newly emphasized asset is TERN-701, an oral allosteric inhibitor of tyrosine kinase oncoprotein BCR-ABL1 (a.k.a. the Philadelphia chromosome) that is being evaluated in a Phase 1 trial for the treatment of chronic myeloid leukemia [CML]. Originating in the bone marrow, CML is responsible for ~15%, or ~9,000 of the newly diagnosed cases of leukemia in American adults annually. Current therapies include tyrosine kinase inhibitors (TKIs) such as Gleevec (imatinib), Tasigna (nilotinib), and recently approved (October 2021) Scemblix (asciminib) from Novartis (NVS); Sprycel (dasatinib) from Bristol Myers Squibb (BMY); and Pfizer’s (PFE) Bosulif (bosutinib), along with chemotherapy. However, due to an increasing number of patients failing on TKIs, there is an unmet need in the CML indication. August Company Presentation The primary reason patients are becoming more refractory to TKIs is active-site mutations that overcome or evade treatment. Furthermore, TKIs are hampered by off-target toxicity. The only approved allosteric TKI (Scemblix) has demonstrated some ability to improve on the shortcomings of first and second generation TKIs because it binds to the myristoyl-binding pocket, inhibiting the BCR-ABL1 gene and most mutations, which are responsible for the proliferation of leukemia cells. As a result, Scemblix has blockbuster potential in its currently approved third line setting with multi-blockbuster potential if Novartis obtains approval for it as a front-line therapy. However, due to certain factors, including twice-daily dosing, a three-hour fasting requirement, some potentially harmful drug interactions, and off-target toxicity, adherence on Scemblix is likely to be challenging. Terns believes that its allosteric candidate TERN-701 can overcome these limitations by better pharmacokinetics, allowing for once-daily dosing with minimal fasting requirements. August Company Presentation That said, TERN-701 has been out-licensed to Hansoh Pharmaceuticals (OTCPK:HNSPF) for development in China with domestic advancement plans still on the drawing board – most likely via a development partner. Hansoh initiated a two-part Phase 1 study in 2Q22, with the initial dose escalation phase to be followed by cytogenetic response evaluation at six months in part two. No timeline for data has been forwarded. August Company Presentation TERN-601. Terns now lists TERN-601 second in its investor-targeted material. It is an oral glucagon-like peptide-1 receptor (GLP-1R) agonist for the treatment of obesity, a malady that afflicts one-half of Americans, although only 2% seek treatment. The company believes GLP-1R agonism can increase insulin secretion by the pancreas, reduce glucagon secretion in the liver, slow gastric emptying, increase satiation, and reduce inflammation – all of which should lead to weight loss. Synthetic GLP-1 peptide semaglutide, marketed as Wegovy, Ozempic, and Rybelsus by Novo Nordisk (NVO), is approved for weight management and type-2 diabetes. However, Wegovy and Ozempic are once-weekly injectables and oral Rybelsus is only approved for lowering A1C (blood sugar) levels in type-2 diabetes patients, like Ozempic. Furthermore, semaglutide is a biologic, which is less stable and harder to administer than small-molecule therapeutics. An oral version for weight loss may require significantly higher doses for weight loss versus A1C reduction. Terns aims to improve on Wegovy with its oral, small-molecule alternative. TERN-601 is expected to enter the clinic in 2023. TERN-101. When Terns went public, its lead program was TERN-101, a liver-distributed, non-bile acid Farnesoid X receptor [FXR] agonist that was being studied in the treatment of NASH. However, data released in June 2021 from a Phase 2a study ((LIFT)) showed that it was well-tolerated, but it decreased high-density lipoproteins (good cholesterol), increased low-density lipoproteins (bad cholesterol), and only demonstrated statistically significant improvements in two of eight NASH biomarkers. TERN-501. As such, TERN-101 has advanced sideways into a NASH Phase 2a study [DUET] with TERN-501, an orally administered THR-β agonist. THR-β is a thyroid hormone receptor found in the liver and is responsible for fatty acid synthesis and liver fat removal through fatty acid oxidation. THR-β agonism has been clinically shown to reduce liver fat and atherogenic (fatty plaque promoting) lipids; however, this approach is plagued by unintended activation of THR-α, which can result in cardiotoxicity, muscle wasting, and reduced bone mineral density. TERN-501 is 23 times more selective for THR-β than THR-α; thus minimizing those risks. DUET will enroll 140 patients across seven arms: three TERN-501 monotherapy doses; one TERN-101 monotherapy dose; two combination doses; and one placebo. Primary endpoint is relative change from baseline in liver fat content as measured by MRI-PDFF (magnetic resonance imaging – proton density fat fraction) at week 12 for TERN-501 monotherapy versus placebo. The first patient was dosed in July 2022 with top-line data anticipated in 2H23. August Company Presentation
Seeking Alpha • Aug 08

Terns Pharmaceuticals GAAP EPS of -$0.55 beats by $0.08

Terns Pharmaceuticals press release (NASDAQ:TERN): Q2 GAAP EPS of -$0.55 beats by $0.08.  As of June 30, 2022, cash, cash equivalents and marketable securities were $139.8 million as compared with $166.0 million as of December 31, 2021.

Rendement pour les actionnaires

TERNUS PharmaceuticalsUS Marché
7D0.04%-1.5%2.6%
1Y1,641.8%30.4%26.2%

Rendement vs Industrie: TERN a dépassé le secteur US Pharmaceuticals qui a rapporté 30.4 % au cours de l'année écoulée.

Rendement vs marché: TERN a dépassé le marché US qui a rapporté 26.2 % au cours de l'année écoulée.

Volatilité des prix

Is TERN's price volatile compared to industry and market?
TERN volatility
TERN Average Weekly Movement4.1%
Pharmaceuticals Industry Average Movement9.9%
Market Average Movement7.2%
10% most volatile stocks in US Market16.1%
10% least volatile stocks in US Market3.2%

Cours de l'action stable: TERN n'a pas connu de volatilité de prix significative au cours des 3 derniers mois par rapport au marché US.

Volatilité au fil du temps: La volatilité hebdomadaire de TERN a diminué de 14% à 4% au cours de l'année écoulée.

À propos de l'entreprise

FondéeSalariésPDGSite web
201659Amy Burroughswww.ternspharma.com

Terns Pharmaceuticals, Inc. est une société biopharmaceutique en phase clinique qui développe des produits candidats à base de petites molécules pour le traitement de l'oncologie et de l'obésité. La société développe TERN-701, un inhibiteur allostérique de la tyrosine kinase BCR-ABL (TKI) qui est en phase 1/2 d'essai clinique pour la leucémie myéloïde chronique (LMC), une forme de cancer qui se développe dans la moelle osseuse. Elle développe également TERN-501, un agoniste bêta du récepteur de l'hormone thyroïdienne avec une stabilité métabolique et une distribution hépatique améliorées, qui est en essai clinique de phase IIa pour le traitement de la stéatohépatite associée à un dysfonctionnement métabolique (MASH) ; et la série TERN-801 de modulateurs du récepteur du polypeptide insulinotrope dépendant du glucose (GIPR) à petites molécules pour le traitement de l'obésité.

Terns Pharmaceuticals, Inc. Résumé des fondamentaux

Comment les bénéfices et les revenus de Terns Pharmaceuticals se comparent-ils à sa capitalisation boursière ?
TERN statistiques fondamentales
Capitalisation boursièreUS$6.11b
Bénéfices(TTM)-US$96.21m
Recettes(TTM)n/a
0.0x
Ratio P/S
-63.5x
Ratio P/E

Le site TERN est-il surévalué ?

Voir Juste valeur et analyse de l'évaluation

Bénéfices et recettes

Principales statistiques de rentabilité tirées du dernier rapport sur les bénéfices (TTM)
TERN compte de résultat (TTM)
RecettesUS$0
Coût des recettesUS$0
Marge bruteUS$0
Autres dépensesUS$96.21m
Les revenus-US$96.21m

Derniers bénéfices déclarés

Dec 31, 2025

Prochaine date de publication des résultats

s/o

Résultat par action (EPS)-0.83
Marge brute0.00%
Marge bénéficiaire nette0.00%
Ratio dettes/capitaux propres0%

Quelles ont été les performances à long terme de TERN?

Voir les performances historiques et les comparaisons

Analyse de l'entreprise et données financières

DonnéesDernière mise à jour (heure UTC)
Analyse de l'entreprise2026/05/08 17:47
Cours de l'action en fin de journée2026/05/04 00:00
Les revenus2025/12/31
Revenus annuels2025/12/31

Sources de données

Les données utilisées dans notre analyse de l'entreprise proviennent de S&P Global Market Intelligence LLC. Les données suivantes sont utilisées dans notre modèle d'analyse pour générer ce rapport. Les données sont normalisées, ce qui peut entraîner un délai avant que la source ne soit disponible.

PaquetDonnéesCadre temporelExemple de source américaine *
Finances de l'entreprise10 ans
  • Compte de résultat
  • Tableau des flux de trésorerie
  • Bilan
Estimations consensuelles des analystes+3 ans
  • Prévisions financières
  • Objectifs de prix des analystes
Prix du marché30 ans
  • Cours des actions
  • Dividendes, scissions et actions
Propriété10 ans
  • Actionnaires principaux
  • Délits d'initiés
Gestion10 ans
  • L'équipe dirigeante
  • Conseil d'administration
Principaux développements10 ans
  • Annonces de l'entreprise

* Exemple pour les titres américains ; pour les titres non américains, des formulaires réglementaires et des sources équivalentes sont utilisés.

Sauf indication contraire, toutes les données financières sont basées sur une période annuelle mais mises à jour trimestriellement. C'est ce qu'on appelle les données des douze derniers mois (TTM) ou des douze derniers mois (LTM). En savoir plus.

Modèle d'analyse et flocon de neige

Les détails du modèle d’analyse utilisé pour générer ce rapport sont disponibles sur notre page Github; nous proposons également des guides expliquant comment utiliser nos rapports et des tutoriels sur Youtube.

Découvrez l'équipe de classe mondiale qui a conçu et construit le modèle d'analyse Simply Wall St.

Indicateurs de l'industrie et du secteur

Nos indicateurs de secteur et de section sont calculés toutes les 6 heures par Simply Wall St. Les détails de notre processus sont disponibles sur Github.

Sources des analystes

Terns Pharmaceuticals, Inc. est couverte par 19 analystes. 6 de ces analystes ont soumis les estimations de revenus ou de bénéfices utilisées comme données d'entrée dans notre rapport. Les soumissions des analystes sont mises à jour tout au long de la journée.

AnalysteInstitution
Etzer DaroutBarclays
Etzer DaroutBMO Capital Markets Equity Research
Evan SeigermanBMO Capital Markets Equity Research