Ionis Pharmaceuticals, Inc.

NasdaqGS:IONS Rapport sur les actions

Capitalisation boursière : US$12.5b

Ionis Pharmaceuticals Gestion

Gestion contrôle des critères 4/4

Le PDG Ionis Pharmaceuticals est Brett Monia, nommé en Jan2020, a un mandat de 6.33 ans. La rémunération annuelle totale est $ 13.35M, composée du salaire de 7.9% et des bonus 92.1%, y compris les actions et options de la société. détient directement 0.15% des actions de la société, d'une valeur de $ 18.39M. La durée moyenne de mandat de l'équipe de direction et du conseil d'administration est respectivement 6.3 ans et 10 ans.

Informations clés

Brett Monia

Directeur général

US$13.4m

Rémunération totale

Pourcentage du salaire du PDG7.88%
Durée du mandat du directeur général6.3yrs
Propriété du PDG0.1%
Durée moyenne d'occupation des postes de direction6.3yrs
Durée moyenne du mandat des membres du conseil d'administration10yrs

Mises à jour récentes de la gestion

Recent updates

Article d’analyse May 11

Need To Know: Analysts Are Much More Bullish On Ionis Pharmaceuticals, Inc. (NASDAQ:IONS) Revenues

Shareholders in Ionis Pharmaceuticals, Inc. ( NASDAQ:IONS ) may be thrilled to learn that the analysts have just...
Mise à jour du récit May 02

IONS: Priority FDA Reviews In 2026 Will Support Stronger Earnings Power

Analysts have nudged the Ionis Pharmaceuticals fair value estimate higher to $130 from $120, citing a series of price target increases across the Street and updated assumptions around growth, profitability, and future P/E levels. Analyst Commentary Recent Street research around Ionis Pharmaceuticals has leaned constructive, with a cluster of bullish analysts lifting price targets and reinforcing a positive view on execution and long term growth potential, even as one firm trimmed its target.
Article d’analyse May 01

Earnings Beat: Ionis Pharmaceuticals, Inc. (NASDAQ:IONS) Just Beat Analyst Forecasts, And Analysts Have Been Lifting Their Forecasts

Ionis Pharmaceuticals, Inc. ( NASDAQ:IONS ) just released its first-quarter report and things are looking bullish. The...
Mise à jour du récit Apr 18

IONS: Priority Review For Severe Triglycerides Will Reframe 2026 Risk Reward Profile

Analysts have raised their fair value estimate for Ionis Pharmaceuticals by about $3 to $96.73, citing updated assumptions for higher revenue growth, a wider profit margin, and a lower future P/E multiple, along with a series of recent price target increases and positive ratings resets from major firms. Analyst Commentary Recent research updates on Ionis Pharmaceuticals have leaned constructive, with several firms lifting price targets and reiterating positive ratings following the latest quarterly results and pipeline updates.
Mise à jour du récit Apr 04

IONS: Priority FDA Reviews In 2026 Will Support Stronger Profitability Profile

Analysts have lifted the Ionis Pharmaceuticals fair value estimate by $3.24 to $120.00, as they factor in updated assumptions around revenue growth, profit margins, and future P/E multiples following recent price target increases across the Street. Analyst Commentary Bullish analysts have been lifting Ionis Pharmaceuticals price targets across several research updates, which feeds directly into the higher fair value estimate.
Mise à jour du récit Mar 20

IONS: Priority Review For Severe Triglycerides Will Shape 2026 Outlook

Ionis Pharmaceuticals' updated analyst price target moves higher to $93.90 from $90.67. Analysts point to recent target hikes, Q4 results commentary and upcoming 2026 catalysts as key supports for this shift.
Seeking Alpha Mar 20

Ionis Pharmaceuticals' Peak Olezarsen Revenues Are Likely Very Conservative

Summary Ionis Pharmaceuticals (IONS) projects $2B+ peak revenue for Olezarsen, but I believe this is highly conservative given the U.S. addressable market. Olezarsen demonstrated a 72% reduction in triglycerides and 85% reduction in acute pancreatitis events, with no comparable competition in efficacy. Current guidance assumes reaching only 10% of the 1M high-risk U.S. sHTG patients, with pricing likely near $20,000 per patient annually. U.S.-only projections, limited initial rollout, and a robust pipeline suggest significant upside potential beyond current market expectations. Read the full article on Seeking Alpha
Mise à jour du récit Mar 06

IONS: 2026 Regulatory Event Risk Will Test Elevated Expectations

Ionis Pharmaceuticals' fair value estimate has been raised from $43.00 to about $62.78 as analysts factor in higher long term revenue growth assumptions, updated margin expectations, and recent price target increases following Q4 results, olezarsen progress, and a busy 2026 catalyst calendar. Analyst Commentary Recent Street research on Ionis Pharmaceuticals points to a more constructive stance on the story overall, but there are still threads of caution that matter if you are thinking about risk, valuation, and execution over the next couple of years.
Mise à jour du récit Feb 19

IONS: Late-Stage RNA Programs Will Support Stronger Future Profitability Profile

Analysts have lifted their price target on Ionis Pharmaceuticals by $10, citing updated expectations around revenue growth, profit margins and a lower future P/E assumption, as reflected in recent research from firms covering the stock. Analyst Commentary Recent Street research points to a generally constructive tone on Ionis Pharmaceuticals, with bullish analysts highlighting both valuation and execution angles in their updated work.
Mise à jour du récit Feb 05

IONS: Triglyceride Market Shift And SHTG Launch Progress Will Shape Outlook

Analysts nudged their fair value target for Ionis Pharmaceuticals slightly higher to about US$90.67 from roughly US$90.63, citing updated assumptions around discount rates, revenue growth, profit margins and a higher future P/E, along with recent Street research that highlights evolving expectations for the triglyceride lowering market where Ionis and Arrowhead both participate. Analyst Commentary Bullish Takeaways Bullish analysts view the refreshed fair value near US$90.67 as consistent with a company that could justify a higher future P/E, reflecting confidence in execution rather than only near term trading sentiment.
Mise à jour du récit Jan 22

IONS: Upcoming SHTG Data And Launch Execution Will Support Bullish Thesis

Analysts have lifted their fair value estimate for Ionis Pharmaceuticals to about US$90.63 from roughly US$89.40, citing updated models that reflect recent Q3 performance, higher assumed revenue growth and profit margins, as well as a lower future P/E. This comes alongside Street price target increases to US$94 and US$99 following Tryngolza driven strength and expectations around upcoming SHTG data.
Mise à jour du récit Jan 08

IONS: Late-Stage Data And New Launches Will Shape Balanced Risk Profile

Analysts nudged their fair value estimate for Ionis Pharmaceuticals higher from about $85.95 to roughly $89.40. They pointed to updated models that reflect recent price target increases, added expectations for Tryngolza in FCS and severe hypertriglyceridemia, and revised long term margin and P/E assumptions.
Mise à jour du récit Dec 24

IONS: Late-Stage RNA Pipeline Will Drive Stronger Profitability Outlook

Analysts have raised their fair value estimate for Ionis Pharmaceuticals from approximately $96 to about $117 per share, citing strong Q3 outperformance led by Tryngolza, expanded peak sales assumptions for key lipid programs, and growing confidence in the late-stage pipeline and path to profitability. Analyst Commentary Bullish analysts are increasingly constructive on Ionis Pharmaceuticals following a series of positive catalysts, including strong Q3 performance from Tryngolza, encouraging late-stage data, and visible progress toward breakeven and long term profitability.
Mise à jour du récit Dec 10

IONS: Late-Stage Data And Multiple Launches Will Shape Balanced Long-Term Outlook

Analysts have modestly raised their fair value estimate for Ionis Pharmaceuticals to approximately $86 per share. This reflects higher peak sales assumptions for Tryngolza and other late stage programs, a slightly richer pricing outlook in severe hypertriglyceridemia, and growing confidence in the company reaching multi billion dollar revenue and profitability in the early 2030s.
Mise à jour du récit Nov 26

IONS: Upcoming Late-Stage Data and Recent Regulatory Progress Will Shape Balanced Outlook

Ionis Pharmaceuticals’ analyst price target has been raised from approximately $82 to $85 per share. This reflects analyst optimism following strong Phase 3 trial results, upward sales guidance, and an improved clinical and commercial outlook across multiple pipeline programs.
Mise à jour du récit Nov 05

IONS: Continued Clinical Success Will Drive Meaningful Upside After Recent Regulatory Wins

The consensus analyst price target for Ionis Pharmaceuticals has increased significantly, rising from approximately $77 to over $82. Analysts cite robust clinical trial results, new product milestones, and a strengthened commercial outlook as key drivers behind their upward revisions.
Article d’analyse Nov 01

Earnings Update: Here's Why Analysts Just Lifted Their Ionis Pharmaceuticals, Inc. (NASDAQ:IONS) Price Target To US$81.91

Ionis Pharmaceuticals, Inc. ( NASDAQ:IONS ) defied analyst predictions to release its third-quarter results, which were...
Mise à jour du récit Oct 22

Analyst Commentary Highlights Ionis Pharmaceuticals’ Upward Price Target and Valuation Amid Key Clinical Wins

Ionis Pharmaceuticals’ analyst price target has been raised from approximately $73 to $77. Analysts cite stronger-than-expected clinical and commercial progress across key late-stage programs, as well as expanded opportunities in rare disease markets.
Mise à jour du récit Oct 08

Pipeline Milestones And Expanding Patient Pools Will Broaden Market Reach

Ionis Pharmaceuticals’ analyst price target has been raised from approximately $69.48 to $73.03, as analysts cite strong Phase 3 results across multiple programs and expanded opportunities in ultra-rare indications, which support increased sales and profit expectations. Analyst Commentary Recent analyst updates on Ionis Pharmaceuticals reveal a nuanced outlook as the company benefits from significant clinical milestones and expanding commercial prospects, but also faces some areas of uncertainty.
Mise à jour du récit Sep 23

Pipeline Milestones And Expanding Patient Pools Will Broaden Market Reach

Analysts increased their price targets for Ionis Pharmaceuticals following "groundbreaking" Phase 3 data for olezarsen, blockbuster expectations, and a major regulatory win for Dawnzera, resulting in a modest consensus target rise from $68.35 to $69.48. Analyst Commentary Bullish analysts significantly raised price targets after Phase 3 trial data for olezarsen/Tryngolza in severe hypertriglyceridemia showed "groundbreaking" or "highly statistically significant" triglyceride reductions and, notably, the first proven benefit in reducing acute pancreatitis.
Article d’analyse Sep 03

Ionis Pharmaceuticals, Inc.'s (NASDAQ:IONS) 34% Share Price Surge Not Quite Adding Up

Despite an already strong run, Ionis Pharmaceuticals, Inc. ( NASDAQ:IONS ) shares have been powering on, with a gain of...
Mise à jour du récit Aug 27

Pipeline Milestones And Expanding Patient Pools Will Broaden Market Reach

Ionis Pharmaceuticals’ consensus price target edged up to $59.19 as analysts cited favorable FDA approval and label for Dawnzera in hereditary angioedema, strong initial launches, and growing pipeline confidence as key drivers, outweighing modest concerns on Wainua revenues. Analyst Commentary FDA approval of Dawnzera with a favorable, broad label (including both every four and eight week dosing) and absence of major safety warnings, positioning it competitively against Takhzyro and Andembry in hereditary angioedema.
Article d’analyse Aug 01

Analysts Just Published A Bright New Outlook For Ionis Pharmaceuticals, Inc.'s (NASDAQ:IONS)

Celebrations may be in order for Ionis Pharmaceuticals, Inc. ( NASDAQ:IONS ) shareholders, with the analysts delivering...
Article d’analyse Jul 30

Is Ionis Pharmaceuticals (NASDAQ:IONS) Using Too Much Debt?

Howard Marks put it nicely when he said that, rather than worrying about share price volatility, 'The possibility of...
Article d’analyse Jul 03

Ionis Pharmaceuticals, Inc.'s (NASDAQ:IONS) Shares Climb 28% But Its Business Is Yet to Catch Up

Despite an already strong run, Ionis Pharmaceuticals, Inc. ( NASDAQ:IONS ) shares have been powering on, with a gain of...
Article d’analyse May 30

We Discuss Why Ionis Pharmaceuticals, Inc.'s (NASDAQ:IONS) CEO Compensation May Be Closely Reviewed

Key Insights Ionis Pharmaceuticals will host its Annual General Meeting on 5th of June Salary of US$1.01m is part of...
Seeking Alpha Apr 22

Ionis: Potentially A Great Time To Buy Ahead Of Q1 Earnings (Upgrade)

Summary Ionis will announce its Q1 earnings on April 30th - in my view, the company is in a strong position and its current valuation of $4.5bn is far too low. The company recently secured approval for olezarsen in FCS, and looks odds on for a follow-up approval in SHTG - a "blockbuster" indication. Management believes >$3bn revenues and >$2bn royalties + milestones may be achieveable long-term, with multiple new product launches for wholly-owned and partnered assets. Rival Alnylam enjoys a >$30bn market cap valuation, suggesting Ionis, whose share price may have been artificially depressed by "tariff-gate", may be significantly undervalued. My research suggests Ionis could represent a "strong buy" opportunity as its share price continue to build momentum after hitting a 30-month low of <$25 per share earlier this month. Read the full article on Seeking Alpha
User avatar
Nouveau récit Mar 20

Anticipated Drug Launches Will Shift Biotech Company To Commercial Stage

Ionis is set to boost revenue through first-mover advantage with TRYNGOLZA and other product launches targeting unmet medical needs.

Analyse de la rémunération des PDG

Comment la rémunération de Brett Monia a-t-elle évolué par rapport aux bénéfices de Ionis Pharmaceuticals?
DateRémunération totaleSalaireBénéfices de l'entreprise
Mar 31 2026n/an/a

-US$327m

Dec 31 2025US$13mUS$1m

-US$381m

Sep 30 2025n/an/a

-US$256m

Jun 30 2025n/an/a

-US$268m

Mar 31 2025n/an/a

-US$458m

Dec 31 2024US$15mUS$1m

-US$454m

Sep 30 2024n/an/a

-US$359m

Jun 30 2024n/an/a

-US$366m

Mar 31 2024n/an/a

-US$385m

Dec 31 2023US$13mUS$961k

-US$366m

Sep 30 2023n/an/a

-US$409m

Jun 30 2023n/an/a

-US$309m

Mar 31 2023n/an/a

-US$329m

Dec 31 2022US$7mUS$825k

-US$270m

Sep 30 2022n/an/a

US$7m

Jun 30 2022n/an/a

-US$28m

Mar 31 2022n/an/a

-US$4m

Dec 31 2021US$13mUS$800k

-US$29m

Sep 30 2021n/an/a

-US$608m

Jun 30 2021n/an/a

-US$550m

Mar 31 2021n/an/a

-US$495m

Dec 31 2020US$11mUS$700k

-US$444m

Sep 30 2020n/an/a

US$94m

Jun 30 2020n/an/a

US$145m

Mar 31 2020n/an/a

US$169m

Dec 31 2019US$7mUS$528k

US$281m

Rémunération vs marché: La rémunération totale de Brett ($USD 13.35M ) est dans la moyenne des entreprises de taille similaire sur le marché US ($USD 14.84M ).

Rémunération et revenus: La rémunération de Brett a été cohérente avec les performances de l'entreprise au cours de l'année écoulée.


PDG

Brett Monia (64 yo)

6.3yrs
Titularisation
US$13,350,777
Compensation

Dr. Brett P. Monia, Ph.D. is a Founder of Ionis Pharmaceuticals, Inc. in 1989 and has been Chief Executive Officer since January 2020. He has extensive experience across a range of therapeutic areas, inclu...


Équipe de direction

NomPositionTitularisationCompensationPropriété
Brett Monia
Founder6.3yrsUS$13.35m0.15%
$ 18.4m
Elizabeth Hougen
Executive VP of Finance & CFO13.3yrsUS$4.42m0.050%
$ 6.3m
Patrick O'Neil
Executive VP13.3yrsUS$3.21m0.038%
$ 4.7m
Eric Swayze
Executive Vice President of Research6.3yrsUS$3.23m0.020%
$ 2.5m
Brian Birchler
Executive Vice President of Corporate & Development Operations6.3yrsUS$3.24m0.041%
$ 5.1m
Richard Geary
Strategic Consultantless than a yearUS$3.33m0.036%
$ 4.5m
Eugene Schneider
Executive VP2.7yrspas de données0.039%
$ 4.8m
Darren Gonzales
Chief Accounting Officer & Senior VP6.3yrspas de donnéespas de données
C. Bennett
Executive VP & Chief Scientific Officer6.3yrsUS$958.87k0.049%
$ 6.1m
D. Walke
Senior Vice President of Investor Relationsno datapas de donnéespas de données
Tracy Berns
Senior VP and Chief Compliance & Quality Assurance Officerno datapas de donnéespas de données
Hayley Soffer
Vice President of Corporate Communications2.3yrspas de donnéespas de données
6.3yrs
Durée moyenne de l'emploi
61yo
Âge moyen

Gestion expérimentée: L'équipe dirigeante de IONS est chevronnée et expérimentée (6.3 années d'ancienneté moyenne).


Membres du conseil d'administration

NomPositionTitularisationCompensationPropriété
Brett Monia
Founder7.2yrsUS$13.35m0.15%
$ 18.4m
B. Parshall
Director25.7yrsUS$538.78k0.031%
$ 3.9m
Joan Herman
Independent Director6.9yrsUS$541.28k0.028%
$ 3.5m
Joseph Klein
Independent Director20.4yrsUS$543.78k0.0067%
$ 842.8k
Joseph Wender
Lead Independent Director32.3yrsUS$598.78k0.031%
$ 3.9m
Michael Hayden
Independent Director7.7yrsUS$528.78k0.034%
$ 4.3m
Spencer Berthelsen
Independent Director24yrsUS$548.78k0.094%
$ 11.8m
Joseph Loscalzo
Independent Chairman of the Board12.3yrsUS$568.78k0.022%
$ 2.8m
Allene Diaz
Independent Director4.9yrsUS$531.28k0.0023%
$ 289.3k
Michael Yang
Independent Director2.4yrsUS$518.78k0.0048%
$ 601.1k
10.0yrs
Durée moyenne de l'emploi
71yo
Âge moyen

Conseil d'administration expérimenté: Les membres du conseil d'administration de IONS sont considérés comme expérimentés (ancienneté moyenne 10 ans).


Analyse de l'entreprise et données financières

DonnéesDernière mise à jour (heure UTC)
Analyse de l'entreprise2026/05/22 06:28
Cours de l'action en fin de journée2026/05/22 00:00
Les revenus2026/03/31
Revenus annuels2025/12/31

Sources de données

Les données utilisées dans notre analyse de l'entreprise proviennent de S&P Global Market Intelligence LLC. Les données suivantes sont utilisées dans notre modèle d'analyse pour générer ce rapport. Les données sont normalisées, ce qui peut entraîner un délai avant que la source ne soit disponible.

PaquetDonnéesCadre temporelExemple de source américaine *
Finances de l'entreprise10 ans
  • Compte de résultat
  • Tableau des flux de trésorerie
  • Bilan
Estimations consensuelles des analystes+3 ans
  • Prévisions financières
  • Objectifs de prix des analystes
Prix du marché30 ans
  • Cours des actions
  • Dividendes, scissions et actions
Propriété10 ans
  • Actionnaires principaux
  • Délits d'initiés
Gestion10 ans
  • L'équipe dirigeante
  • Conseil d'administration
Principaux développements10 ans
  • Annonces de l'entreprise

* Exemple pour les titres américains ; pour les titres non américains, des formulaires réglementaires et des sources équivalentes sont utilisés.

Sauf indication contraire, toutes les données financières sont basées sur une période annuelle mais mises à jour trimestriellement. C'est ce qu'on appelle les données des douze derniers mois (TTM) ou des douze derniers mois (LTM). En savoir plus.

Modèle d'analyse et flocon de neige

Les détails du modèle d’analyse utilisé pour générer ce rapport sont disponibles sur notre page Github; nous proposons également des guides expliquant comment utiliser nos rapports et des tutoriels sur Youtube.

Découvrez l'équipe de classe mondiale qui a conçu et construit le modèle d'analyse Simply Wall St.

Indicateurs de l'industrie et du secteur

Nos indicateurs de secteur et de section sont calculés toutes les 6 heures par Simply Wall St. Les détails de notre processus sont disponibles sur Github.

Sources des analystes

Ionis Pharmaceuticals, Inc. est couverte par 44 analystes. 25 de ces analystes ont soumis les estimations de revenus ou de bénéfices utilisées comme données d'entrée dans notre rapport. Les soumissions des analystes sont mises à jour tout au long de la journée.

AnalysteInstitution
James BirchenoughBarclays
Eliana MerleBarclays
Huidong WangBarclays