Agios Pharmaceuticals, Inc.

NasdaqGS:AGIO Rapport sur les actions

Capitalisation boursière : US$2.5b

Agios Pharmaceuticals Résultats passés

Passé contrôle des critères 0/6

Agios Pharmaceuticals a connu une croissance annuelle moyenne de ses bénéfices de 25.9%, tandis que le secteur Biotechs a vu ses bénéfices augmenter de en hausse à 36.2% par an. Les revenus ont augmenté de en hausse à un taux moyen de 51.4% par an.

Informations clés

25.91%

Taux de croissance des bénéfices

24.71%

Taux de croissance du BPA

Biotechs Croissance de l'industrie17.04%
Taux de croissance des recettes51.39%
Rendement des fonds propres-38.10%
Marge nette-639.84%
Prochaine mise à jour des résultats30 Jul 2026

Mises à jour récentes des performances passées

Recent updates

Mise à jour du récit Jul 07

AGIO: Sickle Cell Priority Review Momentum Will Limit Future Share Upside

Agios Pharmaceuticals' fair value estimate has moved from $28.00 to $31.00 as analysts factor in the recent series of higher price targets tied to FDA Priority Review for mitapivat in sickle cell disease, along with expectations for an accelerated launch timeline supported by an expanding hematologist prescriber base. Analyst Commentary Recent Street research on Agios Pharmaceuticals highlights a mix of optimism around mitapivat in sickle cell disease and a more cautious stance on execution risk, label breadth, and broader biotech sector conditions.
Article d’analyse Jun 17

Agios Pharmaceuticals (AGIO) Stock Could Be 22% Undervalued After RISE UP Phase 3 Data

Agios Pharmaceuticals (AGIO) stock is back in focus after the company shared detailed 52 week data from its RISE UP Phase 3 trial of mitapivat in sickle cell disease at EHA 2026. See our latest analysis for Agios Pharmaceuticals. Agios Pharmaceuticals shares have recently picked up momentum, with a 7 day share price return of 10.25% and a 30 day share price return of 12.87%. However, the 1 year total shareholder return is still down 10.31%, showing short term enthusiasm against a mixed longer...
Mise à jour du récit Jun 16

AGIO: Sickle Cell FDA Path And Thalassemia Launch Will Restrain Stock Enthusiasm

Analysts have trimmed their average price targets on Agios Pharmaceuticals stock, with recent moves such as JPMorgan's cut to $31 from $36 and BofA's adjustment to $40 from $41. These changes reflect a focus on mitapivat's thalassemia launch, the sickle cell disease regulatory path, and the pipeline changes following tebapivat's discontinued development in lower risk myelodysplastic syndromes.
Mise à jour du récit Jun 02

AGIO: Sickle Cell FDA Path And Thalassemia Launch Will Drive Next Phase Upside

Agios Pharmaceuticals' updated analyst price target has shifted slightly lower to $40.88 from $41.13, as analysts factor in the tebapivat setback and refocus their models on mitapivat launch execution and the sickle cell disease regulatory path. Analyst Commentary Recent Street research on Agios Pharmaceuticals highlights a split view, with some analysts focusing on potential value from mitapivat and regulatory milestones, while others concentrate on pipeline setbacks, competitive pressures and addressable market questions.
Seeking Alpha May 29

Agios: 'Sell' On Tebapivat Setback LR-MDS And Competitive PK Activator Drug Class

Summary Agios Pharmaceuticals, Inc. is initiated at Sell due to pipeline setbacks and intensifying competition in PK activators. AGIO discontinued tebapivat in LR-MDS after failing a phase 2b threshold, leaving SCD as its primary near-term catalyst. Novo Nordisk's etavopivat has achieved positive phase 3 SCD results and is expected to file for approval in the 2nd half of 2026. Despite $1B in cash, company faces uncertain differentiation and commercial prospects for tebapivat in SCD, with current sales momentum limited in PYRUKYND and AQVESME. Read the full article on Seeking Alpha
Mise à jour du récit May 18

AGIO: FDA Sickle Cell Decision And Trial Data Will Shape Next Phase Upside

Analysts have trimmed their consolidated price target for Agios Pharmaceuticals by about $0.40 to roughly $41.10. This reflects updated assumptions on market size, profit margins and future P/E after a mix of recent target cuts and raises across the Street.
Mise à jour du récit May 01

AGIO: Sickle Cell FDA Path And Novo Readthroughs Will Shape Future Enthusiasm

Analysts have adjusted their outlook on Agios Pharmaceuticals with a modestly lower average price target, reflecting updated assumptions around discount rates, revenue growth, profit margins and future P/E following recent mixed research, including several target cuts tied to Novo Nordisk related market views and earlier target hikes linked to potential regulatory catalysts for mitapivat. Analyst Commentary Recent Street research on Agios Pharmaceuticals shows a mix of optimism around potential regulatory catalysts for mitapivat and caution around market sizing and competitive readthroughs, particularly following data points tied to Novo Nordisk.
Mise à jour du récit Apr 16

AGIO: Sickle Cell Regulatory Uncertainty Will Continue To Restrain Enthusiasm

Analysts have raised their price target on Agios Pharmaceuticals by $3 to a new fair value estimate of $28, citing recent target increases from major firms and growing attention on upcoming regulatory and clinical catalysts. Analyst Commentary Recent Street research on Agios Pharmaceuticals reflects a mix of optimism around upcoming regulatory events and ongoing caution around execution risks, valuation and timing of potential catalysts.
Mise à jour du récit Apr 02

AGIO: Upcoming Regulatory Decisions In Sickle Cell Disease Will Drive Next Phase Upside

Analysts have adjusted the fair value estimate for Agios Pharmaceuticals to $41.50 from $39.88, citing updated price targets and expectations tied to upcoming regulatory clarity on mitapivat, as well as broader support from recent research commentary. Analyst Commentary Recent Street research on Agios Pharmaceuticals centers on price target revisions, expectations around regulatory clarity for mitapivat in sickle cell disease, and the implications of the recent approval of Aqvesme.
Mise à jour du récit Mar 18

AGIO: Regulatory Clarity On Mitapivat In Sickle Cell Disease Will Drive Next Phase Upside

Analysts have lifted the fair value estimate for Agios Pharmaceuticals by $1 to $39.88, citing higher price targets, expectations for regulatory clarity around mitapivat in sickle cell disease, and the recent approval of Aqvesme as key drivers of their updated outlook. Analyst Commentary Recent Street research reflects a mix of optimism and caution around Agios Pharmaceuticals, with several price target revisions clustering in the US$25 to US$46 range and commentary centered on regulatory milestones, the impact of Aqvesme, and broader biotech sector conditions.
Mise à jour du récit Mar 04

AGIO: Thalassemia Decision And Recent Approval Will Drive Next Phase Upside

Analysts have nudged their intrinsic value estimate for Agios Pharmaceuticals higher to about $38.88 from $36.75, reflecting refreshed price targets in the $25 to $35 range and updated models following recent product approval and broader biotech sector tailwinds cited in recent research. Analyst Commentary Bullish Takeaways Bullish analysts are lifting price targets into the mid US$20s to mid US$30s, which aligns with the higher intrinsic value estimate around US$38.88 and indicates they see room for the shares to better reflect updated assumptions.
Mise à jour du récit Feb 18

AGIO: Sickle Cell Setback Will Continue To Restrain Enthusiasm Despite Thalassemia Approval

Analysts have lifted their fair value estimate for Agios Pharmaceuticals shares from $20 to $25, citing updated models that reflect recent drug approvals, ongoing FDA review milestones, and a series of higher Street price targets across the biotech sector. Analyst Commentary Recent Street research on Agios Pharmaceuticals reflects a split view, with several bullish initiations and target hikes alongside more cautious revisions that highlight execution and growth risks around the company’s pipeline and commercial plans.
Mise à jour du récit Feb 03

AGIO: Thalassemia Decision And Aqvesme Approval Will Define Post RISE UP Upside

Narrative Update: Agios Pharmaceuticals (AGIO) Analysts have lifted Agios Pharmaceuticals' price targets into a US$25 to US$38 range, with recent tweaks to models reflecting the approval of Aqvesme, updated views on mitapivat and Pyrukynd, and a generally more constructive stance on U.S. biotech capital and deal activity. Analyst Commentary Recent Street research on Agios Pharmaceuticals shows a wide spread of views, with price targets clustered in the US$25 to US$38 range after earlier cuts from much higher levels.
Mise à jour du récit Jan 20

AGIO: Upcoming Thalassemia Decision Will Shape Post RISE UP Opportunity Narrative

Agios Pharmaceuticals’ fair value estimate edges up from US$36.00 to US$36.75 as analysts recalibrate models following recent target changes across the Street, reflecting updated views on Pyrukynd’s opportunity set, revised profit margin assumptions, and a higher future P/E multiple, despite some ongoing trial related uncertainties. Analyst Commentary Street research around Agios has become more divided, with some analysts leaning into the updated opportunity around Pyrukynd and other mitapivat indications, while others focus on execution risk and regulatory uncertainty following the RISE UP sickle cell disease data.
Mise à jour du récit Jan 06

AGIO: Upcoming FDA Thalassemia Decision Will Shape Post RISE UP Bullish Outlook

Analysts have lifted their aggregate fair value estimate for Agios Pharmaceuticals to $36.00 from $32.13, citing updated revenue and margin assumptions. This follows mixed views on the recent RISE UP data and new Street targets that range widely from US$20 to US$48, alongside Citi's fresh US$38 initiation and a near-term FDA catalyst watch.
Mise à jour du récit Dec 18

AGIO: Sickle Cell Setback Will Drive Cautious View Despite Upcoming FDA Decision

Analysts have cut their average price target on Agios Pharmaceuticals to $20 from $37, reflecting reduced expectations for mitapivat in sickle cell disease and more conservative long term revenue and expense assumptions, even as some still see upside around upcoming regulatory catalysts for Pyrukynd. Analyst Commentary Bearish analysts have responded to the RISE UP data by sharply recalibrating expectations for mitapivat in sickle cell disease, cutting price targets and, in some cases, ratings.
Mise à jour du récit Dec 04

AGIO: Upcoming FDA Decision Will Drive Bullish Outlook After Mixed Trial Data

Analysts have reduced their average price target on Agios Pharmaceuticals from about $42 to roughly $32 per share. This reflects higher perceived risk after mixed Phase 3 RISE UP data, tempered revenue and margin expectations, and a wider debate over the regulatory and commercial outlook for mitapivat and Pyrukynd across indications.
Mise à jour du récit Nov 20

AGIO: Regulatory Decisions Will Drive Outlook After Mixed Late-Stage Clinical Results

Agios Pharmaceuticals’ analyst price target has been reduced from approximately $47.50 to $42.33 per share. Analysts cite increased uncertainty for mitapivat in sickle cell disease following underwhelming Phase 3 trial results, as well as a more challenging regulatory and commercial pathway.
Mise à jour du récit Sep 05

FDA Approval And Global Partnerships Will Yield Mixed Prospects

Analysts modestly trimmed Agios Pharmaceuticals’ price target from $47.67 to $47.50, reflecting a brief FDA approval delay for Pyrukynd and cautious near-term modeling, while maintaining long-term conviction on the strength of clinical data and emerging commercial partnerships. Analyst Commentary Bullish analysts remain confident in FDA approval of Pyrukynd despite a three-month PDUFA delay due to the submission of a REMS for hepatocellular injury, which is viewed as a standard regulatory step and not due to new data requests.
Article d’analyse Feb 20

Why Agios Pharmaceuticals' (NASDAQ:AGIO) Earnings Are Weaker Than They Seem

We didn't see Agios Pharmaceuticals, Inc.'s ( NASDAQ:AGIO ) stock surge when it reported robust earnings recently. We...
Seeking Alpha Feb 14

Agios Pharmaceuticals: Liver Toxicity Issues May Threaten Thalassemia Approval (Rating Downgrade)

Summary Agios Pharmaceuticals' focus is on expanding Pyrukund's label to treat thalassemia and sickle cell disease, targeting multi-billion dollar markets. Despite promising Phase 3 results, safety concerns, namely liver injury, have impacted Agios' stock and could affect Pyrukund's approval and market adoption. Agios has a strong cash position of $1.5bn and potential blockbuster revenue opportunity, but safety issues warrant a cautious "Hold" rating. Monitoring progress and awaiting further clarity on safety issues and FDA decisions is advisable before making investment moves. Read the full article on Seeking Alpha
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Nouveau récit Feb 09

Mitapivat May Launch In 2025 For Blood Disorders But Faces Regulatory And Competition Challenges

Mitapivat's launch in thalassemia and sickle cell markets promises revenue growth from new opportunities, leveraging positive Phase III data for adoption.
Seeking Alpha Jan 14

Agios Pharmaceuticals: Considering Risk/Reward Ahead Of FDA Decision

Summary Agios Pharma submitted a sNDA to the FDA after two Phase III trials studying PYRUKYND (mitapivat) in thalassemia met their primary endpoints last year. The FDA has set a goal date of Sept. 7th 2025 to review the application and render a decision. Agios is well capitalized after $1.1 billion in milestones following the FDA's approval of vorasidenib, a drug divested when the company exited oncology in 2021. A third Phase III study named RISE UP has recruited patients to study PYRUKYND in sickle cell disease with results due in late-2025. Agios Pharma is rated a HOLD until further clarity on the commercialization of PYRUKYND occurs later this year. Read the full article on Seeking Alpha
Seeking Alpha Dec 03

Agios Pharmaceuticals: A Long Overdue Follow Up

Summary Today, we take a deeper look at commercial stage biopharma firm Agios Pharmaceuticals for the first time in more than two years. The shares have spiked up recently thanks in a large part to a huge cash infusion the company received in August. The company's one approved product on the market, PYRUKYND, has seen limited sales to date, but the compound is being evaluated to treat much larger potential indications. Read the full article on Seeking Alpha
Article d’analyse Sep 26

We're Not Very Worried About Agios Pharmaceuticals' (NASDAQ:AGIO) Cash Burn Rate

Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...
Seeking Alpha Aug 27

Agios' Mitapivat: A Potential Blockbuster In Thalassemia Treatment

Summary Agios’ Pyrukynd is FDA-approved for pyruvate kinase deficiency but generated modest sales of $8.6 million in Q2 2024. Mitapivat shows promise in treating SCD and thalassemia, with ongoing Phase 3 trials showing positive results for hemoglobin improvement. Expanding Pyrukynd’s label to include pediatric and thalassemia indications is crucial, with regulatory filings expected by 2025. Agios has a strong financial position, with a cash runway extending beyond 2027, bolstered by milestone payments. Despite risks, Agios’ mitapivat could become a blockbuster drug, making AGIO a compelling buy for biotech investors. Read the full article on Seeking Alpha
Article d’analyse Aug 04

Agios Pharmaceuticals, Inc. (NASDAQ:AGIO) Just Released Its Second-Quarter Earnings: Here's What Analysts Think

Agios Pharmaceuticals, Inc. ( NASDAQ:AGIO ) just released its latest second-quarter report and things are not looking...

Ventilation des recettes et des dépenses

Comment Agios Pharmaceuticals gagne et dépense de l'argent. Sur la base des derniers bénéfices déclarés, sur une base LTM.


Historique des gains et des recettes

NasdaqGS:AGIO Recettes, dépenses et bénéfices (USD Millions )
DateRecettesLes revenusDépenses G+ADépenses de R&D
31 Mar 2666-4231870
31 Dec 2554-4131800
30 Sep 2545-4011800
30 Jun 25416501780
31 Mar 25376661670
31 Dec 24366741570
30 Sep 24336741400
30 Jun 2431-3651280
31 Mar 2429-3531230
31 Dec 2327-3521200
30 Sep 2324-2201170
30 Jun 2320-2101210
31 Mar 2319-2181190
31 Dec 2214-2321220
30 Sep 2210-3671200
30 Jun 226-3691180
31 Mar 221-3601190
31 Dec 210-3571210
30 Sep 210-342116221
30 Jun 210-337117221
31 Mar 210-336117221
31 Dec 200-3291150
30 Sep 2035-3471240
30 Jun 2061-3741290
31 Mar 2088-4021320
31 Dec 190-301102214
30 Sep 19112-4011290
30 Jun 19102-3891270
31 Mar 19116-3481210
31 Dec 1894-3461140
30 Sep 1874-3431050
30 Jun 1870-325910
31 Mar 1841-339810
31 Dec 1743-315710
30 Sep 1756-283640
30 Jun 1753-269580
31 Mar 1749-241550
31 Dec 1670-198510
30 Sep 1653-183460
30 Jun 1650-160440
31 Mar 1656-136400
31 Dec 1559-118360
30 Sep 1568-104320

Des revenus de qualité: AGIO n'est actuellement pas rentable.

Augmentation de la marge bénéficiaire: AGIO n'est actuellement pas rentable.


Analyse des flux de trésorerie disponibles par rapport aux bénéfices


Analyse de la croissance passée des bénéfices

Tendance des revenus: AGIO n'est pas rentable, mais a réduit ses pertes au cours des 5 dernières années à un taux de 25.9% par an.

Accélération de la croissance: Impossible de comparer la croissance des bénéfices de AGIO au cours de l'année écoulée à sa moyenne sur 5 ans car elle n'est actuellement pas rentable

Bénéfices par rapport au secteur d'activité: AGIO n'est pas rentable, ce qui rend difficile la comparaison de sa croissance des bénéfices de l'année écoulée avec celle du secteur Biotechs ( 54.5% ).


Rendement des fonds propres

ROE élevé: AGIO a un retour sur capitaux propres négatif ( -38.1% ), car il n'est actuellement pas rentable.


Rendement des actifs


Rendement des capitaux employés


Découvrir des entreprises performantes dans le passé

Analyse de l'entreprise et données financières

DonnéesDernière mise à jour (heure UTC)
Analyse de l'entreprise2026/07/10 01:22
Cours de l'action en fin de journée2026/07/10 00:00
Les revenus2026/03/31
Revenus annuels2025/12/31

Sources de données

Les données utilisées dans notre analyse de l'entreprise proviennent de S&P Global Market Intelligence LLC. Les données suivantes sont utilisées dans notre modèle d'analyse pour générer ce rapport. Les données sont normalisées, ce qui peut entraîner un délai avant que la source ne soit disponible.

PaquetDonnéesCadre temporelExemple de source américaine *
Finances de l'entreprise10 ans
  • Compte de résultat
  • Tableau des flux de trésorerie
  • Bilan
Estimations consensuelles des analystes+3 ans
  • Prévisions financières
  • Objectifs de prix des analystes
Prix du marché30 ans
  • Cours des actions
  • Dividendes, scissions et actions
Propriété10 ans
  • Actionnaires principaux
  • Délits d'initiés
Gestion10 ans
  • L'équipe dirigeante
  • Conseil d'administration
Principaux développements10 ans
  • Annonces de l'entreprise

* Exemple pour les titres américains ; pour les titres non américains, des formulaires réglementaires et des sources équivalentes sont utilisés.

Sauf indication contraire, toutes les données financières sont basées sur une période annuelle mais mises à jour trimestriellement. C'est ce qu'on appelle les données des douze derniers mois (TTM) ou des douze derniers mois (LTM). En savoir plus.

Modèle d'analyse et flocon de neige

Les détails du modèle d'analyse utilisé pour générer ce rapport sont disponibles sur notre page Github, nous proposons également des guides pour apprendre à utiliser nos rapports et des tutoriels sur YouTube.

Découvrez l'équipe de classe mondiale qui a conçu et construit le modèle d'analyse Simply Wall St.

Indicateurs de l'industrie et du secteur

Nos indicateurs de secteur et de section sont calculés toutes les 6 heures par Simply Wall St. Les détails de notre processus sont disponibles sur Github.

Sources des analystes

Agios Pharmaceuticals, Inc. est couverte par 28 analystes. 10 de ces analystes ont soumis les estimations de revenus ou de bénéfices utilisées comme données d'entrée dans notre rapport. Les soumissions des analystes sont mises à jour tout au long de la journée.

AnalysteInstitution
Peter LawsonBarclays
George FarmerBMO Capital Markets Equity Research
Alec StranahanBofA Global Research