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Zymeworks Inc.Informe acción NasdaqGS:ZYME

Capitalización bursátil US$1.9b
Precio de las acciones
US$25.61
US$40.08
36.1% infravalorado descuento intrínseco
1Y121.9%
7D7.0%
1D
Valor de la cartera
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Zymeworks Inc.

Informe acción NasdaqGS:ZYME

Capitalización de mercado: US$1.9b

Zymeworks (ZYME) Resumen de Acciones

Zymeworks Inc, empresa de biotecnología, desarrolla bioterapéuticos para el tratamiento del cáncer, la inflamación y las enfermedades autoinmunes. Saber más

Análisis fundamental de ZYME
Puntuación del snowflake
Valoración3/6
Crecimiento futuro4/6
Rendimiento pasado0/6
Salud financiera5/6
Dividendos0/6

Recompensas

Análisis de riesgos

No se han detectado riesgos en ZYME a partir de nuestros controles de riesgos.

ZYME Community Fair Values

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Competidores de Zymeworks Inc.

Historial de precios y rendimiento

Resumen de las cotizaciones máximas, mínimas y variaciones del Zymeworks
Precios históricos de las acciones
Precio actual de la acciónUS$25.61
Máximo en las últimas 52 semanasUS$29.75
Mínimo de 52 semanasUS$11.02
Beta1.19
Cambio en 1 mes-8.86%
Variación en 3 meses11.40%
Cambio de 1 año121.92%
Variación en 3 años210.42%
Variación en 5 años-17.92%
Variación desde la OPV97.00%

Noticias y actualizaciones recientes

Seeking Alpha May 22

Zymeworks: Royalty-Backed Biotech Flywheel With Underappreciated ADC Optionality

Summary Zymeworks is transitioning into an oncology royalty platform with a robust internal discovery engine, offering a differentiated risk-reward profile versus traditional biotech peers. ZYME's balance sheet is fortified with over $400 million in liquid assets, a $440 million milestone pipeline, and a $125 million share repurchase program, supporting operations beyond 2028. Zanidatamab's Priority Review for first-line HER2-positive GEA, with a PDUFA date of August 25, 2026, could trigger $265 million in near-term milestone payments and unlock substantial royalty streams. Valuation reflects a discounted forward P/E and justified premium EV/Sales, while risks include regulatory outcomes, commercial execution by partners, and early-stage pipeline uncertainties. Read the full article on Seeking Alpha
Actualización de narrativa May 15

ZYME: Royalty-Focused Model And 2026 Oncology Milestones Will Drive Upside

Narrative Update on Zymeworks Analysts have nudged their outlook on Zymeworks higher, with recent price target moves to $46, $47 and $48 framed around the $250m Royalty Pharma debt deal and a greater focus on royalty income, even as updated assumptions now reflect modestly lower fair value alongside higher discount rates, revenue growth, profit margin and a reduced future P/E multiple. Analyst Commentary Bullish analysts are clustering around a similar message for Zymeworks, with recent research tying higher price targets to the US$250m Royalty Pharma debt deal and a clearer tilt toward royalty income.
Actualización de narrativa Apr 29

ZYME: Royalty Model Shift Will Rely On Upcoming HER2 Gastric Trial Data

Narrative Update on Zymeworks Analysts have lifted Zymeworks' implied price target range into the mid to high $40s, citing the $250m Royalty Pharma debt deal and a shift toward a more royalty focused model as key reasons for refining assumptions around profitability and a higher future P/E multiple. Analyst Commentary Recent Street research has been broadly constructive on Zymeworks, with several price target increases clustered in the mid to high $40s.

Recent updates

Seeking Alpha May 22

Zymeworks: Royalty-Backed Biotech Flywheel With Underappreciated ADC Optionality

Summary Zymeworks is transitioning into an oncology royalty platform with a robust internal discovery engine, offering a differentiated risk-reward profile versus traditional biotech peers. ZYME's balance sheet is fortified with over $400 million in liquid assets, a $440 million milestone pipeline, and a $125 million share repurchase program, supporting operations beyond 2028. Zanidatamab's Priority Review for first-line HER2-positive GEA, with a PDUFA date of August 25, 2026, could trigger $265 million in near-term milestone payments and unlock substantial royalty streams. Valuation reflects a discounted forward P/E and justified premium EV/Sales, while risks include regulatory outcomes, commercial execution by partners, and early-stage pipeline uncertainties. Read the full article on Seeking Alpha
Actualización de narrativa May 15

ZYME: Royalty-Focused Model And 2026 Oncology Milestones Will Drive Upside

Narrative Update on Zymeworks Analysts have nudged their outlook on Zymeworks higher, with recent price target moves to $46, $47 and $48 framed around the $250m Royalty Pharma debt deal and a greater focus on royalty income, even as updated assumptions now reflect modestly lower fair value alongside higher discount rates, revenue growth, profit margin and a reduced future P/E multiple. Analyst Commentary Bullish analysts are clustering around a similar message for Zymeworks, with recent research tying higher price targets to the US$250m Royalty Pharma debt deal and a clearer tilt toward royalty income.
Actualización de narrativa Apr 29

ZYME: Royalty Model Shift Will Rely On Upcoming HER2 Gastric Trial Data

Narrative Update on Zymeworks Analysts have lifted Zymeworks' implied price target range into the mid to high $40s, citing the $250m Royalty Pharma debt deal and a shift toward a more royalty focused model as key reasons for refining assumptions around profitability and a higher future P/E multiple. Analyst Commentary Recent Street research has been broadly constructive on Zymeworks, with several price target increases clustered in the mid to high $40s.
Actualización de narrativa Apr 14

ZYME: Royalty Model Outlook Will Hinge On Upcoming HER2 Gastric Cancer Data

Analysts have raised Zymeworks’ fair value estimate from about $36.46 to $40.08, citing higher price targets in the $46 to $48 range, supportive views on the $250m Royalty Pharma financing, and a shift toward a more royalty-focused business model. Analyst Commentary Recent Street research has focused on Zymeworks’ financing decisions, its pivot toward a royalty-driven model, and the pipeline events that could influence how investors think about execution and valuation.
Actualización de narrativa Mar 31

ZYME: Royalty Model Shift And FY26 Catalysts Will Drive Future Upside

Analysts have lifted their Zymeworks price target range into the mid $40s, citing the $250m Royalty Pharma financing and the company's tilt toward a more royalty-focused model, along with upcoming clinical and R&D milestones, as key supports for the higher valuations. Analyst Commentary Bullish analysts are clustering around price targets in the mid US$40s, reflecting a view that the recent US$250m Royalty Pharma financing and the pivot toward royalties could support higher valuations if execution stays on track.
Actualización de narrativa Mar 17

ZYME: Royalty Model Shift And Debt Deal Will Drive Future Upside

Narrative Update: Zymeworks Analyst Price Target Shift The analyst price target for Zymeworks has moved from $48.27 to $55.34, with analysts pointing to the recent $250m Royalty Pharma debt deal, a more royalty-focused model, and upcoming clinical and R&D milestones as key factors supporting the higher valuation range cited in recent reports of $46 to $48. Analyst Commentary Bullish analysts are leaning into a more constructive view on Zymeworks, with several price targets now clustered in the mid to high US$40s range.
Actualización de narrativa Mar 03

ZYME: Cancer Trial Success And Royalty Potential Will Drive Future Upside

Analysts have raised their price target on Zymeworks from $42.00 to approximately $48.27, citing updated assumptions around revenue growth, profit margins and future P/E expectations. What's in the News Chief Financial and Business Officer Leone Patterson plans to leave Zymeworks in the first quarter of 2026, with her role ending January 9, 2026, and employment concluding January 31, 2026 (company announcement).
Actualización de narrativa Feb 17

ZYME: Royalty Model Will Be Supported By Upcoming HER2 Gastric Cancer Data

Analysts have raised their price targets on Zymeworks, with one firm moving to $40 from $37 and another to $25 from $17, citing the company's shift toward a royalty-focused model and expectations around upcoming HERIZON GEA-01 data as key drivers. Analyst Commentary Bullish Takeaways Bullish analysts point to the shift toward a royalty-focused model as a key reason for higher price targets, arguing that recurring royalty streams can support more visible revenue over time.
Nueva narrativa Feb 11

ADC And T Cell Engager Setbacks Will Test Reliance On Milestones Yet Offer Long-Term Upside

Catalysts About Zymeworks Zymeworks is a clinical stage biotechnology company focused on antibody drug conjugates, T cell engagers and partnered biologics for oncology and inflammatory diseases. What are the underlying business or industry changes driving this perspective?
Actualización de narrativa Feb 03

ZYME: Royalty Model Will Be Driven By Positive HER2 Gastric Cancer Data

Narrative Update Analysts have nudged their blended price target for Zymeworks higher from about $34.50 to roughly $35.62 as they factor in the company’s shift toward a royalty-focused model around zani, positive HERIZON-GEA data for Ziihera, and updated views on future profitability and P/E assumptions. Analyst Commentary Street research on Zymeworks is clustering around two main themes: the shift toward a royalty-focused model centered on zani, and the impact of recent clinical data for Ziihera and early pipeline assets.
Actualización de narrativa Jan 19

ZYME: Royalty Model And Cancer Data Will Drive Future Upside

Analysts have lifted their price targets on Zymeworks into a US$25 to US$42 range, citing the shift toward a royalty-focused model, positive HERIZON-GEA-01 data for Ziihera and Zani, and early but encouraging readouts for ZW191 and ZW251 as key drivers of their updated views. Analyst Commentary Bullish analysts are reacting positively to Zymeworks' shift toward a royalty-focused model and the recent clinical updates for Ziihera, Zani, ZW191, and ZW251.
Actualización de narrativa Jan 05

ZYME: Royalty Aggregator Model And Cancer Data Will Drive Future Upside

Analysts have lifted their price targets on Zymeworks into a roughly US$25 to US$42 range, reflecting their views on the company’s shift toward a royalty-focused model, positive HERIZON-GEA-01 data around Ziihera and Zani, and early ZW191 results that feed into higher assumed profit margins and a richer future P/E multiple in updated models. Analyst Commentary Recent Street research on Zymeworks has been broadly constructive, with several firms revisiting their models after the shift toward a royalty-focused setup and fresh clinical data around Ziihera, Zani and ZW191.
Actualización de narrativa Dec 18

ZYME: Royalty Model And Cancer Data Will Drive Share Outperformance

The analyst fair value estimate for Zymeworks has been raised from $30.00 to $42.00 per share, as analysts point to stronger than expected HERIZON-GEA-01 efficacy data, an expanding royalty-driven model, and upgraded Street price targets as key drivers of higher growth and margin assumptions. Analyst Commentary Bullish analysts are increasingly framing Zymeworks as a higher quality growth story, citing a transition toward a recurring, royalty-driven revenue model and stronger than expected efficacy data from HERIZON GEA-01.
Actualización de narrativa Dec 04

ZYME: Royalty Model Will Benefit From Positive HER2 Gastric Cancer Data

Analysts nudged their fair value estimate for Zymeworks slightly higher, from $34.20 to $34.50. This reflects growing confidence that the company’s shift toward a royalty aggregator model, coupled with strong HERIZON-GEA-01 data for Ziihera and encouraging early ZW191 results, can drive faster revenue growth and improved profitability.
Actualización de narrativa Nov 20

ZYME: Recurring Royalty Revenue Will Drive Momentum After Positive Clinical Results

Zymeworks' analyst price target has surged from approximately $24.45 to $34.20 per share. This increase reflects analysts' optimism following the company's positive clinical trial results and strategic shift toward generating recurring royalty revenues.
Artículo de análisis Nov 18

Zymeworks Inc.'s (NASDAQ:ZYME) Shares Climb 30% But Its Business Is Yet to Catch Up

Despite an already strong run, Zymeworks Inc. ( NASDAQ:ZYME ) shares have been powering on, with a gain of 30% in the...
Artículo de análisis Nov 09

Zymeworks Inc. (NASDAQ:ZYME) Just Released Its Third-Quarter Earnings: Here's What Analysts Think

It's been a mediocre week for Zymeworks Inc. ( NASDAQ:ZYME ) shareholders, with the stock dropping 14% to US$16.46 in...
Actualización de narrativa Nov 05

ZYME: Encouraging Pipeline Data Will Drive Momentum Ahead Of Key Clinical Readouts

Analysts have raised their price target for Zymeworks from $23.68 to $24.45 per share. They cite increased confidence in the company's growth outlook following encouraging clinical data and expanding therapeutic opportunities.
Actualización de narrativa Oct 22

Analysts Raise Zymeworks Target on Pipeline Progress While Weighing Risks and Valuation Changes

Analysts have increased their price target for Zymeworks from $21.45 to $23.68 per share. They cite the company's differentiated therapies and upcoming clinical milestones as key drivers for the revised outlook.
Actualización de narrativa Oct 08

Oncology And Biologic Therapies Will Unlock Global Opportunities

Analysts have increased their price target for Zymeworks from $20.06 to $21.45, citing improving revenue growth forecasts, stronger projected profit margins, and growing confidence in the momentum of Zanidatamab in biliary tract cancer. Analyst Commentary Recent commentary from street research reflects a mix of optimism and caution surrounding Zymeworks, particularly as the company advances its lead asset, Zanidatamab, in the biliary tract cancer market.
Actualización de narrativa Sep 20

Oncology And Biologic Therapies Will Unlock Global Opportunities

Despite raised analyst confidence driven by positive clinical momentum for Zanidatamab and anticipated catalysts, Zymeworks’ consensus analyst price target has been modestly lowered from $21.05 to $20.06. Analyst Commentary Positive momentum for Zanidatamab in biliary tract cancer.
Artículo de análisis Sep 07

Optimistic Investors Push Zymeworks Inc. (NASDAQ:ZYME) Shares Up 25% But Growth Is Lacking

The Zymeworks Inc. ( NASDAQ:ZYME ) share price has done very well over the last month, posting an excellent gain of...
Artículo de análisis Aug 10

Zymeworks Inc. Just Reported A Surprise Profit And Analysts Updated Their Estimates

Last week, you might have seen that Zymeworks Inc. ( NASDAQ:ZYME ) released its second-quarter result to the market...
Artículo de análisis Jun 18

There's Reason For Concern Over Zymeworks Inc.'s (NASDAQ:ZYME) Price

There wouldn't be many who think Zymeworks Inc.'s ( NASDAQ:ZYME ) price-to-sales (or "P/S") ratio of 9.1x is worth a...
Artículo de análisis May 14

Analysts Just Shipped A Stunning Upgrade To Their Zymeworks Inc. (NASDAQ:ZYME) Estimates

Zymeworks Inc. ( NASDAQ:ZYME ) shareholders will have a reason to smile today, with the analysts making substantial...
Seeking Alpha Apr 28

Zymeworks: Poised For Growth With Platform Validation

Summary Zymeworks' FDA approval of Ziihera for HER2-positive biliary tract cancer validates its science, partnerships, and positions it for long-term value creation. Financial stability is evident with $76.3 million in revenue in 2024 and a cash runway extending through late 2027. The robust pipeline includes zanidatamab for additional indications and promising early-stage candidates like ZW171 and ZW209 targeting high-unmet need cancers. Competitive landscape and clinical risks exist, but Zymeworks' innovative biologics and strategic partnerships make it a compelling biotech investment. Read the full article on Seeking Alpha
Artículo de análisis Apr 16

We're Hopeful That Zymeworks (NASDAQ:ZYME) Will Use Its Cash Wisely

Just because a business does not make any money, does not mean that the stock will go down. For example, although...
User avatar
Nueva narrativa Mar 25

Ziihera Launch And ZW251 IND Submission Will Broaden Treatment Options

Strategic focus on advanced programs and cost management aims to enhance resource efficiency and net margins through promising returns.
Artículo de análisis Mar 11

Industry Analysts Just Upgraded Their Zymeworks Inc. (NASDAQ:ZYME) Revenue Forecasts By 13%

Zymeworks Inc. ( NASDAQ:ZYME ) shareholders will have a reason to smile today, with the analysts making substantial...
Artículo de análisis Feb 28

Zymeworks Inc.'s (NASDAQ:ZYME) Business Is Yet to Catch Up With Its Share Price

You may think that with a price-to-sales (or "P/S") ratio of 14.8x Zymeworks Inc. ( NASDAQ:ZYME ) is a stock to avoid...
Seeking Alpha Feb 10

Zymeworks: Its Post-Approval Future

Summary Recently approved Ziihera, a bispecific HER2 antibody, shows promise with potential peak sales over $2 billion, contingent on approvals for stomach and breast cancers. Ziihera competes with Enhertu, and partner Jazz Pharmaceuticals is advancing multiple trials to establish its efficacy in various HER2+ cancers. Zymeworks also has multiple early-stage programs and collaborations, leveraging its development platforms to fund its own pipeline. The stock recently has seen significant purchases from a large beneficial owner in the equity as well. An analysis follows around Zymeworks in the paragraphs below. Read the full article on Seeking Alpha
Seeking Alpha Dec 19

Zymeworks: Prime Time For Ziihera, Early-Stage Pipeline Progressing Ahead Of Schedule

Summary The Zymeworks story over the last two years was one of transformation and execution. Ziihera (zanidatamab) was approved in November for the treatment of second line biliary tract cancer and Zymeworks should start generating royalties on net sales this quarter. The phase 3 results for Ziihera in first-line GEA patients are now expected in Q2 2025, and represent the next critical step for Zymeworks and its partner Jazz. The early-stage pipeline is still progressing ahead of schedule and it is also further expanding from oncology to immunology and inflammation. Zymeworks is well-capitalized with a runway into 2H 2027, and the progress over the last two years puts the company in a good position to create long-term value for its shareholders. Read the full article on Seeking Alpha
Artículo de análisis Dec 13

Companies Like Zymeworks (NASDAQ:ZYME) Are In A Position To Invest In Growth

Just because a business does not make any money, does not mean that the stock will go down. For example, although...
Artículo de análisis Nov 08

Optimistic Investors Push Zymeworks Inc. (NASDAQ:ZYME) Shares Up 34% But Growth Is Lacking

Zymeworks Inc. ( NASDAQ:ZYME ) shares have continued their recent momentum with a 34% gain in the last month alone. The...

Rentabilidad de los accionistas

ZYMEUS BiotechsMercado US
7D7.0%1.2%1.1%
1Y121.9%34.6%28.7%

Rentabilidad vs. Industria: ZYME superó a la industria US Biotechs, que obtuvo un rendimiento del 34.6% el año pasado.

Rentabilidad vs. Mercado: ZYME superó al mercado US, que obtuvo un rendimiento del 28.7% el año pasado.

Volatilidad de los precios

Is ZYME's price volatile compared to industry and market?
ZYME volatility
ZYME Average Weekly Movement6.3%
Biotechs Industry Average Movement10.8%
Market Average Movement7.2%
10% most volatile stocks in US Market16.5%
10% least volatile stocks in US Market3.1%

Precio estable de las acciones: ZYME no ha tenido una volatilidad de precios significativa en los últimos 3 meses en comparación con el mercado US.

Volatilidad a lo largo del tiempo: La volatilidad semanal de ZYME (6%) se ha mantenido estable durante el año pasado.

Acerca de la empresa

FundadaEmpleadosCEOPágina web
2003243Ken Galbraithwww.zymeworks.com

Zymeworks Inc, empresa de biotecnología, desarrolla bioterapéuticos para el tratamiento del cáncer, la inflamación y las enfermedades autoinmunes. Entre las plataformas de la empresa figuran la de anticuerpos multiespecíficos Azymetric; la de conjugados de fármacos, que incluye un conjunto de citotoxinas patentadas que comprenden toxinas inhibidoras de la topoisomerasa y la microtubulina, enlazadores estables y tecnologías de conjugación; la plataforma EFECT, que consiste en un conjunto de modificaciones de la región Fc de los anticuerpos; y ProTECT, una plataforma de coestimulación inmunitaria específica de tumores. Sus principales productos candidatos incluyen Ziihera (zanidatamab-hrii), un anticuerpo biespecífico dirigido contra tumores que expresan HER2; zanidatamab para el tratamiento de poblaciones neoadyuvantes, cáncer de mama y otros cánceres que expresan HER2; Pasritamig, un captador biespecífico de células T dirigido contra la calicreína humana 2 para el tratamiento en monoterapia y del cáncer de próstata resistente a la castración; ZW191, un conjugado anticuerpo-fármaco (ADC) de uso clínico dirigido contra los tumores que expresan el receptor alfa del folato, incluidos los cánceres de ovario, endometrio y pulmón de células no pequeñas; ZW251, una molécula de ADC en fase clínica para el tratamiento del carcinoma hepatocelular que expresa glypican 3; ZW220, un ADC dirigido al CPNM y el cáncer de ovario que expresan NaPi2b; ZW209, un nuevo TriTCE dirigido a células tumorales que expresan ligando Delta-like 3 para el tratamiento de tumores sólidos; y ZW1528, una molécula biespecífica para tratar la enfermedad pulmonar obstructiva crónica.

Resumen de fundamentos de Zymeworks Inc.

¿Cómo se comparan los beneficios e ingresos de Zymeworks con su capitalización de mercado?
Estadísticas fundamentales de ZYME
Capitalización bursátilUS$1.87b
Beneficios(TTM)-US$102.66m
Ingresos (TTM)US$81.26m
23.0x
Ratio precio-ventas (PS)
-18.2x
Ratio precio-beneficio (PE)

Beneficios e Ingresos

Estadísticas clave de rentabilidad del último informe de resultados (TTM)
Cuenta de resultados (TTM) de ZYME
IngresosUS$81.26m
Coste de los ingresosUS$135.72m
Beneficio bruto-US$54.46m
Otros gastosUS$48.20m
Beneficios-US$102.66m

Últimos beneficios comunicados

Mar 31, 2026

Próxima fecha de beneficios

n/a

Beneficios por acción (BPA)-1.41
Margen bruto-67.01%
Margen de beneficio neto-126.33%
Ratio deuda/patrimonio0%

¿Cómo se ha desempeñado ZYME a largo plazo?

Ver rendimiento histórico y comparativa

Análisis de la empresa y estado de los datos financieros

DatosÚltima actualización (huso horario UTC)
Análisis de la empresa2026/05/24 17:08
Precio de las acciones al final del día2026/05/22 00:00
Beneficios2026/03/31
Ingresos anuales2025/12/31

Fuentes de datos

Los datos utilizados en nuestro análisis de empresas proceden de S&P Global Market Intelligence LLC. Los siguientes datos se utilizan en nuestro modelo de análisis para generar este informe. Los datos están normalizados, lo que puede introducir un retraso desde que la fuente está disponible.

PaqueteDatosMarco temporalEjemplo Fuente EE.UU. *
Finanzas de la empresa10 años
  • Cuenta de resultados
  • Estado de tesorería
  • Balance
Estimaciones del consenso de analistas+3 años
  • Previsiones financieras
  • Objetivos de precios de los analistas
Precios de mercado30 años
  • Precios de las acciones
  • Dividendos, escisiones y acciones
Propiedad10 años
  • Accionistas principales
  • Información privilegiada
Gestión10 años
  • Equipo directivo
  • Consejo de Administración
Principales avances10 años
  • Anuncios de empresas

* Ejemplo para valores de EE.UU., para no EE.UU. se utilizan formularios y fuentes normativas equivalentes.

A menos que se especifique lo contrario, todos los datos financieros se basan en un periodo anual, pero se actualizan trimestralmente. Esto se conoce como datos de los últimos doce meses (TTM) o de los últimos doce meses (LTM). Más información.

Modelo de análisis y copo de nieve

Los detalles del modelo de análisis utilizado para generar este informe están disponibles en nuestra página de Github, también tenemos guías sobre cómo utilizar nuestros informes y tutoriales en Youtube.

Conozca al equipo de talla mundial que diseñó y construyó el modelo de análisis Simply Wall St.

Métricas industriales y sectoriales

Simply Wall St calcula cada 6 horas nuestras métricas sectoriales y de sección. Los detalles de nuestro proceso están disponibles en Github.

Fuentes analistas

Zymeworks Inc. está cubierta por 21 analistas. 12 de esos analistas presentaron las estimaciones de ingresos o ganancias utilizadas como datos para nuestro informe. Las estimaciones de los analistas se actualizan a lo largo del día.

AnalistaInstitución
Tania Armstrong-WhitworthATB Cormark Historical (Cormark Securities)
David MartinBloom Burton & Co.
Mayank MamtaniB. Riley Securities, Inc.