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Terns Pharmaceuticals, Inc.Informe acción NasdaqGS:TERN

Capitalización bursátil US$6.1b
Precio de las acciones
US$52.95
US$98.57
46.3% infravalorado descuento intrínseco
1Y1,641.8%
7D0.04%
1D
Valor de la cartera
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Terns Pharmaceuticals, Inc.

Informe acción NasdaqGS:TERN

Capitalización de mercado: US$6.1b

This company has been acquired

The company may no longer be operating, as it has been acquired. Find out why through their latest events.

Terns Pharmaceuticals (TERN) Resumen de Acciones

Terns Pharmaceuticals, Inc. es una empresa biofarmacéutica en fase clínica que desarrolla productos candidatos de moléculas pequeñas para el tratamiento de la oncología y la obesidad. Saber más

Análisis fundamental de TERN
Puntuación del snowflake
Valoración1/6
Crecimiento futuro0/6
Rendimiento pasado0/6
Salud financiera6/6
Dividendos0/6

Análisis de riesgos

Tiene unos ingresos inferiores a 1 millón de dólares ($0)

Los accionistas han sido diluidos sustancialmente en el último año

Se prevé que los beneficios disminuyan un promedio de 5.7% al año durante los próximos 3 años

Actualmente no es rentable y no se prevé que lo sea en los próximos 3 años


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Competidores de Terns Pharmaceuticals, Inc.

Historial de precios y rendimiento

Resumen de las cotizaciones máximas, mínimas y variaciones del Terns Pharmaceuticals
Precios históricos de las acciones
Precio actual de la acciónUS$52.95
Máximo en las últimas 52 semanasUS$53.19
Mínimo de 52 semanasUS$2.66
Beta-0.38
Cambio en 1 mes0.55%
Variación en 3 meses40.19%
Cambio de 1 año1,641.78%
Variación en 3 años318.25%
Variación en 5 años232.81%
Variación desde la OPV187.93%

Noticias y actualizaciones recientes

Recent updates

Seeking Alpha • Mar 25

Merck's Deal For Terns And Its Stellar CML Drug Candidate Looks Like Good Business

Summary Merck & Co., Inc. acquires Terns Pharmaceuticals, Inc. for $53/share, valuing the deal at ~$6.7bn, to secure TERN-701's blockbuster CML potential. TERN-701's Phase 1 data show a 75% MMR rate at 24 weeks, significantly outperforming current standard-of-care therapies like Novartis' Scemblix. MRK seeks to offset looming Keytruda patent expiry by adding high-potential oncology assets, with TERN-701 positioned as a future growth driver. While the acquisition introduces execution and regulatory risks, MRK's diversified pipeline and strategic M&A activity support a long-term bullish outlook. Read the full article on Seeking Alpha
Artículo de análisis • Sep 19

Terns Pharmaceuticals (NASDAQ:TERN) Is In A Good Position To Deliver On Growth Plans

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although Amazon.com...
Seeking Alpha • Feb 08

Terns Pharma: I Don't See The Positioning

Summary Terns Pharmaceuticals' lead molecules, TERN-701 and TERN-601, face stiff competition from established and more effective treatments in CML and obesity markets. TERN-701's advantage of food-independent dosing may not be sufficient to challenge entrenched CML treatments like Asciminib. TERN-601 showed modest weight loss results but falls short compared to competitors like semaglutide and Amgen's MariTide. With a market cap of $383mn and trading at cash, Terns' strategy of developing copycat molecules appears unpromising; I recommend avoiding this stock. Read the full article on Seeking Alpha
Seeking Alpha • Oct 21

Terns Pharmaceuticals: Another Potential GLP-1 Entrant

Summary Terns Pharmaceuticals' stock has risen somewhat due to some optimism around its early-stage clinical programs, particularly TERN-601 for obesity and TERN-701 for CML. TERN-601 showed promising Phase 1 results, leading to a capital raise extending the cash runway to 2028, with Phase 2 trials expected in 2025. TERN-701, targeting CML, has interim Phase 1 data expected in December 2024, with potential to address unmet needs in the $5 billion CML market. An updated analysis around Terns Pharmaceuticals follows in the paragraphs below. Read the full article on Seeking Alpha
Seeking Alpha • Sep 25

Terns Pharmaceuticals: Obesity Advancement Continues With Other Q1 2025 Program Catalyst

Summary Terns Pharmaceuticals is developing TERN-601, an oral GLP-1R agonist, which showed a placebo-adjusted weight loss of 4.9% in a phase 1 trial for obesity treatment. The company plans to initiate a phase 2 study for TERN-601 in 2025, creating a significant catalyst opportunity for investors. The company is also developing TERN-701 for chronic myeloid leukemia, with interim phase 1 data expected in December 2024, offering another investment opportunity. The global anti-obesity drugs market is expected to reach $100 billion by 2030. Read the full article on Seeking Alpha
Seeking Alpha • Sep 10

Terns Pharmaceuticals: Weight Loss Drug TERN-601 Is Competitive

Summary Terns Pharmaceuticals' TERN-601 shows impressive weight loss results in a phase 1 study, positioning TERN competitively in the obesity drug market. The commercial viability of TERN-601's manufacturing scalability could be an advantage over certain competitors like Novo Nordisk's Rybelsus. TERN has sufficient funds to support operations into 2026, and a recent $125M public offering could allow it to go further. Read the full article on Seeking Alpha
Seeking Alpha • Sep 20

Terns Pharmaceuticals: The Easy Money Has Been Made

Summary Shares of biotech concern Terns Pharmaceuticals are up some 150% after consummating a secondary offering at $2.42 a share, announced on August 12, 2022. Despite the bump, shares of Terns Pharmaceuticals are still down significantly from their IPO pricing back in January 2021, as the once solely NASH-focused company is making a foray into leukemia. With NASH, obesity, and oncology assets but few near-terms catalysts, the significant beneficial owner buying of Terns Pharmaceuticals on the secondary merited a deeper dive. A full investment analysis follows in the paragraphs below. Don’t fear what other people can do. Fear most what you could have done, but didn’t.” ― Craig D. Lounsbrough Today, we take our first look at a small developmental concern. The company has had a significant change of focus, recently did a capital raise, and has several "shots on goal." An analysis follows below. Seeking Alpha Company Overview: Terns Pharmaceuticals, Inc. (TERN) is a Foster City, California-based early clinical-stage biopharmaceutical concern focused on the development of small-molecule therapeutics for indications with high unmet needs. The company currently has four candidates in the clinic undergoing evaluation in the treatment of two diseases, and a fifth asset that should enter the clinic in 2023. Terns was formed in 2016 and backed by Eli Lilly (LLY), which out-licensed its non-alcoholic steatohepatitis [NASH] portfolio to the then-startup, along with a Series A investment of $30 million in 2018. The company went public in February 2021, raising net proceeds of $132.9 million at $17 per share. This somewhat thinly traded stock is currently selling at just over six bucks a sharer, translating to a market cap of just under $350 million, after giving effect to 14.63 million pre-funded warrants. Pipeline: After releasing disappointing data from a Phase 1 NASH trial in March 2022, Terns is now leading with a cancer therapy in its corporate presentations and SEC filings. August Company Presentation TERN-701. The newly emphasized asset is TERN-701, an oral allosteric inhibitor of tyrosine kinase oncoprotein BCR-ABL1 (a.k.a. the Philadelphia chromosome) that is being evaluated in a Phase 1 trial for the treatment of chronic myeloid leukemia [CML]. Originating in the bone marrow, CML is responsible for ~15%, or ~9,000 of the newly diagnosed cases of leukemia in American adults annually. Current therapies include tyrosine kinase inhibitors (TKIs) such as Gleevec (imatinib), Tasigna (nilotinib), and recently approved (October 2021) Scemblix (asciminib) from Novartis (NVS); Sprycel (dasatinib) from Bristol Myers Squibb (BMY); and Pfizer’s (PFE) Bosulif (bosutinib), along with chemotherapy. However, due to an increasing number of patients failing on TKIs, there is an unmet need in the CML indication. August Company Presentation The primary reason patients are becoming more refractory to TKIs is active-site mutations that overcome or evade treatment. Furthermore, TKIs are hampered by off-target toxicity. The only approved allosteric TKI (Scemblix) has demonstrated some ability to improve on the shortcomings of first and second generation TKIs because it binds to the myristoyl-binding pocket, inhibiting the BCR-ABL1 gene and most mutations, which are responsible for the proliferation of leukemia cells. As a result, Scemblix has blockbuster potential in its currently approved third line setting with multi-blockbuster potential if Novartis obtains approval for it as a front-line therapy. However, due to certain factors, including twice-daily dosing, a three-hour fasting requirement, some potentially harmful drug interactions, and off-target toxicity, adherence on Scemblix is likely to be challenging. Terns believes that its allosteric candidate TERN-701 can overcome these limitations by better pharmacokinetics, allowing for once-daily dosing with minimal fasting requirements. August Company Presentation That said, TERN-701 has been out-licensed to Hansoh Pharmaceuticals (OTCPK:HNSPF) for development in China with domestic advancement plans still on the drawing board – most likely via a development partner. Hansoh initiated a two-part Phase 1 study in 2Q22, with the initial dose escalation phase to be followed by cytogenetic response evaluation at six months in part two. No timeline for data has been forwarded. August Company Presentation TERN-601. Terns now lists TERN-601 second in its investor-targeted material. It is an oral glucagon-like peptide-1 receptor (GLP-1R) agonist for the treatment of obesity, a malady that afflicts one-half of Americans, although only 2% seek treatment. The company believes GLP-1R agonism can increase insulin secretion by the pancreas, reduce glucagon secretion in the liver, slow gastric emptying, increase satiation, and reduce inflammation – all of which should lead to weight loss. Synthetic GLP-1 peptide semaglutide, marketed as Wegovy, Ozempic, and Rybelsus by Novo Nordisk (NVO), is approved for weight management and type-2 diabetes. However, Wegovy and Ozempic are once-weekly injectables and oral Rybelsus is only approved for lowering A1C (blood sugar) levels in type-2 diabetes patients, like Ozempic. Furthermore, semaglutide is a biologic, which is less stable and harder to administer than small-molecule therapeutics. An oral version for weight loss may require significantly higher doses for weight loss versus A1C reduction. Terns aims to improve on Wegovy with its oral, small-molecule alternative. TERN-601 is expected to enter the clinic in 2023. TERN-101. When Terns went public, its lead program was TERN-101, a liver-distributed, non-bile acid Farnesoid X receptor [FXR] agonist that was being studied in the treatment of NASH. However, data released in June 2021 from a Phase 2a study ((LIFT)) showed that it was well-tolerated, but it decreased high-density lipoproteins (good cholesterol), increased low-density lipoproteins (bad cholesterol), and only demonstrated statistically significant improvements in two of eight NASH biomarkers. TERN-501. As such, TERN-101 has advanced sideways into a NASH Phase 2a study [DUET] with TERN-501, an orally administered THR-β agonist. THR-β is a thyroid hormone receptor found in the liver and is responsible for fatty acid synthesis and liver fat removal through fatty acid oxidation. THR-β agonism has been clinically shown to reduce liver fat and atherogenic (fatty plaque promoting) lipids; however, this approach is plagued by unintended activation of THR-α, which can result in cardiotoxicity, muscle wasting, and reduced bone mineral density. TERN-501 is 23 times more selective for THR-β than THR-α; thus minimizing those risks. DUET will enroll 140 patients across seven arms: three TERN-501 monotherapy doses; one TERN-101 monotherapy dose; two combination doses; and one placebo. Primary endpoint is relative change from baseline in liver fat content as measured by MRI-PDFF (magnetic resonance imaging – proton density fat fraction) at week 12 for TERN-501 monotherapy versus placebo. The first patient was dosed in July 2022 with top-line data anticipated in 2H23. August Company Presentation
Seeking Alpha • Aug 08

Terns Pharmaceuticals GAAP EPS of -$0.55 beats by $0.08

Terns Pharmaceuticals press release (NASDAQ:TERN): Q2 GAAP EPS of -$0.55 beats by $0.08.  As of June 30, 2022, cash, cash equivalents and marketable securities were $139.8 million as compared with $166.0 million as of December 31, 2021.

Rentabilidad de los accionistas

TERNUS PharmaceuticalsMercado US
7D0.04%5.0%1.1%
1Y1,641.8%44.3%28.7%

Rentabilidad vs. Industria: TERN superó a la industria US Pharmaceuticals, que obtuvo un rendimiento del 44.3% el año pasado.

Rentabilidad vs. Mercado: TERN superó al mercado US, que obtuvo un rendimiento del 28.7% el año pasado.

Volatilidad de los precios

Is TERN's price volatile compared to industry and market?
TERN volatility
TERN Average Weekly Movement4.1%
Pharmaceuticals Industry Average Movement10.1%
Market Average Movement7.2%
10% most volatile stocks in US Market16.5%
10% least volatile stocks in US Market3.1%

Precio estable de las acciones: TERN no ha tenido una volatilidad de precios significativa en los últimos 3 meses en comparación con el mercado US.

Volatilidad a lo largo del tiempo: La volatilidad semanal de TERN ha disminuido de 14% a 4% en el último año.

Acerca de la empresa

FundadaEmpleadosCEOPágina web
201659Amy Burroughswww.ternspharma.com

Terns Pharmaceuticals, Inc, empresa biofarmacéutica en fase clínica, desarrolla productos candidatos de moléculas pequeñas para el tratamiento de la oncología y la obesidad. La empresa desarrolla TERN-701, un inhibidor alostérico de la tirosina quinasa BCR-ABL (TKI) que se encuentra en ensayo clínico de fase 1/2 para la leucemia mieloide crónica (LMC), una forma de cáncer que se origina en la médula ósea. También desarrolla el TERN-501, un agonista beta del receptor de la hormona tiroidea con estabilidad metabólica y distribución hepática mejoradas que se encuentra en ensayo clínico de fase IIa para el tratamiento de la esteatohepatitis asociada a disfunción metabólica (MASH); y la serie TERN-801 de moduladores del receptor insulinotrópico dependiente de la glucosa (GIPR) de moléculas pequeñas para la obesidad.

Resumen de fundamentos de Terns Pharmaceuticals, Inc.

¿Cómo se comparan los beneficios e ingresos de Terns Pharmaceuticals con su capitalización de mercado?
Estadísticas fundamentales de TERN
Capitalización bursátilUS$6.11b
Beneficios(TTM)-US$96.21m
Ingresos (TTM)n/a
0.0x
Ratio precio-ventas (PS)
-63.5x
Ratio precio-beneficio (PE)

¿Está TERN sobrevalorada?

Ver valor justo y análisis de valoración

Beneficios e Ingresos

Estadísticas clave de rentabilidad del último informe de resultados (TTM)
Cuenta de resultados (TTM) de TERN
IngresosUS$0
Coste de los ingresosUS$0
Beneficio brutoUS$0
Otros gastosUS$96.21m
Beneficios-US$96.21m

Últimos beneficios comunicados

Dec 31, 2025

Próxima fecha de beneficios

n/a

Beneficios por acción (BPA)-0.83
Margen bruto0.00%
Margen de beneficio neto0.00%
Ratio deuda/patrimonio0%

¿Cómo se ha desempeñado TERN a largo plazo?

Ver rendimiento histórico y comparativa

Análisis de la empresa y estado de los datos financieros

DatosÚltima actualización (huso horario UTC)
Análisis de la empresa2026/05/08 00:01
Precio de las acciones al final del día2026/05/04 00:00
Beneficios2025/12/31
Ingresos anuales2025/12/31

Fuentes de datos

Los datos utilizados en nuestro análisis de empresas proceden de S&P Global Market Intelligence LLC. Los siguientes datos se utilizan en nuestro modelo de análisis para generar este informe. Los datos están normalizados, lo que puede introducir un retraso desde que la fuente está disponible.

PaqueteDatosMarco temporalEjemplo Fuente EE.UU. *
Finanzas de la empresa10 años
  • Cuenta de resultados
  • Estado de tesorería
  • Balance
Estimaciones del consenso de analistas+3 años
  • Previsiones financieras
  • Objetivos de precios de los analistas
Precios de mercado30 años
  • Precios de las acciones
  • Dividendos, escisiones y acciones
Propiedad10 años
  • Accionistas principales
  • Información privilegiada
Gestión10 años
  • Equipo directivo
  • Consejo de Administración
Principales avances10 años
  • Anuncios de empresas

* Ejemplo para valores de EE.UU., para no EE.UU. se utilizan formularios y fuentes normativas equivalentes.

A menos que se especifique lo contrario, todos los datos financieros se basan en un periodo anual, pero se actualizan trimestralmente. Esto se conoce como datos de los últimos doce meses (TTM) o de los últimos doce meses (LTM). Más información.

Modelo de análisis y copo de nieve

Los detalles del modelo de análisis utilizado para generar este informe están disponibles en nuestra página de Github, también tenemos guías sobre cómo utilizar nuestros informes y tutoriales en Youtube.

Conozca al equipo de talla mundial que diseñó y construyó el modelo de análisis Simply Wall St.

Métricas industriales y sectoriales

Simply Wall St calcula cada 6 horas nuestras métricas sectoriales y de sección. Los detalles de nuestro proceso están disponibles en Github.

Fuentes analistas

Terns Pharmaceuticals, Inc. está cubierta por 19 analistas. 6 de esos analistas presentaron las estimaciones de ingresos o ganancias utilizadas como datos para nuestro informe. Las estimaciones de los analistas se actualizan a lo largo del día.

AnalistaInstitución
Etzer DaroutBarclays
Etzer DaroutBMO Capital Markets Equity Research
Evan SeigermanBMO Capital Markets Equity Research