Silence Therapeutics plc

Informe acción NasdaqGM:SLN

Capitalización de mercado: US$283.9m

Silence Therapeutics Dirección

Dirección controles de criterios 2/4

El CEO de Silence Therapeutics es Iain Ross , nombrado en Dec 2025, tiene una permanencia de menos de un año. compensación anual total es $3.15M, compuesta por 0.5% salario y 99.5% primas, incluidas acciones y opciones de la empresa. posee directamente un 0.028% de las acciones de la empresa, por valor de $80.03K. La antigüedad media del equipo directivo y de la junta directiva es de 2.8 años y 6.3 años, respectivamente.

Información clave

Iain Ross

Chief Executive Officer (CEO)

US$3.1m

Compensación total

Porcentaje del salario del CEO0.54%
Permanencia del CEOless than a year
Participación del CEO0.03%
Permanencia media de la dirección2.8yrs
Promedio de permanencia en la Junta Directiva6.3yrs

Actualizaciones recientes de la dirección

Recent updates

Actualización de narrativa Jun 01

SLN: Future Offering Program Will Shape Upside Risk Reward Profile

Analysts have adjusted their price target on Silence Therapeutics to $31.20. This reflects updated assumptions around growth, profitability and a higher future P/E multiple that together indicate a different risk and reward profile than before.
Artículo de análisis Feb 05

Revenues Working Against Silence Therapeutics plc's (NASDAQ:SLN) Share Price Following 27% Dive

To the annoyance of some shareholders, Silence Therapeutics plc ( NASDAQ:SLN ) shares are down a considerable 27% in...
Artículo de análisis Jan 31

Here's Why We're Watching Silence Therapeutics' (NASDAQ:SLN) Cash Burn Situation

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although Amazon.com...
Seeking Alpha Nov 18

Silence Therapeutics: Divesiran Targets High-Burden PV

Summary Silence Therapeutics is advancing its lead RNAi drug, divesiran, for polycythemia vera, with a fully enrolled Phase 2 trial and results expected in Q3 2026. SLN boasts a strong cash position ($100M+), providing runway through 2028 and enabling continued pipeline development without near-term financing risks. The SANRECO trial's design and patient population position divesiran as a potential adjunctive therapy for high-burden PV patients, focusing on reduced phlebotomy frequency and infrequent dosing. While acknowledging clinical and market risks, I maintain a cautiously optimistic outlook, seeing significant upside if Phase 2 data demonstrate efficacy and safety. Read the full article on Seeking Alpha
Artículo de análisis Oct 19

Here's Why We're Watching Silence Therapeutics' (NASDAQ:SLN) Cash Burn Situation

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although Amazon.com...
Artículo de análisis Sep 28

Pinning Down Silence Therapeutics plc's (NASDAQ:SLN) P/S Is Difficult Right Now

With a median price-to-sales (or "P/S") ratio of close to 9.9x in the Biotechs industry in the United States, you could...
Artículo de análisis Aug 13

Newsflash: Silence Therapeutics plc (NASDAQ:SLN) Analysts Have Been Trimming Their Revenue Forecasts

NasdaqGM:SLN 1 Year Share Price vs Fair Value Explore Silence Therapeutics's Fair Values from the Community and select...
Artículo de análisis Aug 12

Silence Therapeutics plc (NASDAQ:SLN) Second-Quarter Results: Here's What Analysts Are Forecasting For This Year

NasdaqGM:SLN 1 Year Share Price vs Fair Value Explore Silence Therapeutics's Fair Values from the Community and select...
Actualización de narrativa Aug 08

ALPACAR-360 Success And AstraZeneca Collaboration Will Advance siRNA Pipeline

The upward revision in Silence Therapeutics’ price target reflects significantly improved consensus revenue growth forecasts and a lower future P/E multiple, resulting in an increased fair value estimate from $32.37 to $37.26. What's in the News Silence Therapeutics approved the application of Article 159 of its articles of association, effective from the recent AGM to the next annual general meeting.
Artículo de análisis May 11

Silence Therapeutics plc (NASDAQ:SLN) First-Quarter Results Just Came Out: Here's What Analysts Are Forecasting For This Year

The analysts might have been a bit too bullish on Silence Therapeutics plc ( NASDAQ:SLN ), given that the company fell...
Artículo de análisis May 06

Silence Therapeutics plc's (NASDAQ:SLN) Price Is Right But Growth Is Lacking After Shares Rocket 50%

Those holding Silence Therapeutics plc ( NASDAQ:SLN ) shares would be relieved that the share price has rebounded 50...
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Nueva narrativa Apr 01

ALPACAR-360 Success And AstraZeneca Collaboration Will Advance siRNA Pipeline

The company's strategic partnerships and collaborations could reduce financial risk and enhance revenue growth through shared commercialization and milestone payments.
Artículo de análisis Mar 22

Silence Therapeutics plc (NASDAQ:SLN) Looks Inexpensive After Falling 29% But Perhaps Not Attractive Enough

Unfortunately for some shareholders, the Silence Therapeutics plc ( NASDAQ:SLN ) share price has dived 29% in the last...
Artículo de análisis Mar 06

These Analysts Think Silence Therapeutics plc's (NASDAQ:SLN) Sales Are Under Threat

Market forces rained on the parade of Silence Therapeutics plc ( NASDAQ:SLN ) shareholders today, when the analysts...
Artículo de análisis Mar 04

We're Keeping An Eye On Silence Therapeutics' (NASDAQ:SLN) Cash Burn Rate

Just because a business does not make any money, does not mean that the stock will go down. For example, although...
Artículo de análisis Jan 28

Risks Still Elevated At These Prices As Silence Therapeutics plc (NASDAQ:SLN) Shares Dive 26%

Unfortunately for some shareholders, the Silence Therapeutics plc ( NASDAQ:SLN ) share price has dived 26% in the last...
Artículo de análisis Dec 10

Silence Therapeutics plc (NASDAQ:SLN) May Have Run Too Fast Too Soon With Recent 54% Price Plummet

Silence Therapeutics plc ( NASDAQ:SLN ) shareholders that were waiting for something to happen have been dealt a blow...
Artículo de análisis Oct 04

Some Shareholders Feeling Restless Over Silence Therapeutics plc's (NASDAQ:SLN) P/S Ratio

You may think that with a price-to-sales (or "P/S") ratio of 38.4x Silence Therapeutics plc ( NASDAQ:SLN ) is a stock...
Artículo de análisis Aug 18

Silence Therapeutics plc (NASDAQ:SLN) Consensus Forecasts Have Become A Little Darker Since Its Latest Report

As you might know, Silence Therapeutics plc ( NASDAQ:SLN ) last week released its latest second-quarter, and things did...
Artículo de análisis Jun 17

Silence Therapeutics plc's (NASDAQ:SLN) Shareholders Might Be Looking For Exit

You may think that with a price-to-sales (or "P/S") ratio of 26.8x Silence Therapeutics plc ( NASDAQ:SLN ) is a stock...
Artículo de análisis May 21

Here's Why We're Not Too Worried About Silence Therapeutics' (NASDAQ:SLN) Cash Burn Situation

We can readily understand why investors are attracted to unprofitable companies. By way of example, Silence...
Artículo de análisis Feb 07

Need To Know: Analysts Are Much More Bullish On Silence Therapeutics plc (NASDAQ:SLN) Revenues

Silence Therapeutics plc ( NASDAQ:SLN ) shareholders will have a reason to smile today, with the analysts making...
Artículo de análisis Nov 27

Subdued Growth No Barrier To Silence Therapeutics plc (NASDAQ:SLN) With Shares Advancing 65%

Silence Therapeutics plc ( NASDAQ:SLN ) shares have had a really impressive month, gaining 65% after a shaky period...
Seeking Alpha Sep 08

Silence Therapeutics wins FDA’s fast track status for blood cancer therapy

U.K.-based clinical-stage biotech Silence Therapeutics plc (NASDAQ:SLN) announced Thursday that the FDA granted Fast Track Designation to SLN124 as a treatment for polycythemia vera (PV), a type of blood cancer. SLN124, belonging to a drug class called short interfering ribonucleic acid (siRNA) therapeutics, is set to undergo a Phase 1/2 study in PV this year. The FDA offers the Fast Track designation to accelerate the development and review of drugs targeted at serious conditions with unmet medical needs. It allows developers to communicate frequently with the regulator on plans for clinical studies. If certain criteria are met, such programs will also be able to win the Accelerated Approval and Priority Review, enabling them to reach patients sooner. In a clinical trial last year, SLN124 indicated proof of mechanism and was well tolerated among healthy volunteers.
Seeking Alpha Aug 12

Silence Therapeutics prices 5.95M ADSs at $9.50/share

Silence Therapeutics (NASDAQ:SLN) has priced an underwritten offering of 5.95M American Depositary Shares, each representing three ordinary shares, at a price of $9.50/ADS, for aggregate gross proceeds of ~$56.5M. All of the ADSs are being offered by Silence. Offering is expected to close on or about August 16, 2022. Silence intends to use the net proceeds of the offering, together with its existing cash and cash equivalents to fund the advancement of its clinical trials, including its Phase 2 trial of SLN360 in ASCVD and its Phase 1/2 trial of SLN124 in polycythemia vera, as well as expansion of pipeline programs, working capital and general corporate purposes.

Análisis de compensación del CEO

¿Cómo ha cambiado la remuneración de Iain Ross en comparación con los beneficios de Silence Therapeutics?
FechaCompensación totalSalarioIngresos de la empresa
Mar 31 2026n/an/a

-US$75m

Dec 31 2025US$3mUS$17k

-US$89m

Sep 30 2025n/an/a

-US$65m

Jun 30 2025n/an/a

-US$79m

Mar 31 2025n/an/a

-US$72m

Dec 31 2024US$482kn/a

-US$45m

Sep 30 2024n/an/a

-US$73m

Jun 30 2024n/an/a

-US$50m

Mar 31 2024n/an/a

-US$44m

Dec 31 2023US$512kn/a

-US$54m

Sep 30 2023n/an/a

-US$52m

Jun 30 2023n/an/a

-US$53m

Mar 31 2023n/an/a

-US$53m

Dec 31 2022US$673kn/a

-US$50m

Sep 30 2022n/an/a

-US$40m

Jun 30 2022n/an/a

-US$47m

Mar 31 2022n/an/a

-US$51m

Dec 31 2021US$162kn/a

-US$53m

Sep 30 2021n/an/a

-US$57m

Jun 30 2021n/an/a

-US$57m

Mar 31 2021n/an/a

-US$49m

Dec 31 2020US$2mUS$386k

-US$45m

Sep 30 2020n/an/a

-US$33m

Jun 30 2020n/an/a

-US$28m

Mar 31 2020n/an/a

-US$26m

Dec 31 2019US$122kUS$121k

-US$26m

Compensación vs. Mercado: La compensación total de Iain($USD3.15M) está por encima de la media de empresas de tamaño similar en el mercado US ($USD1.66M).

Compensación vs. Ingresos: La compensación de Iain ha aumentado mientras la empresa no es rentable.


CEO

Iain Ross (72 yo)

less than a year
Permanencia
US$3,145,012
Compensación

Mr. Iain Gladstone Ross, B. Sc (Hons) Biochemistry, C. DIR, CH. D., serves as Executive Chairman at Oxford BioDynamics Plc since 2025. He has been the Non-Executive Director of Tern Plc since October 29, 2...


Equipo directivo

NombrePosiciónPermanenciaCompensaciónPropiedad
Iain Ross
Interim CEO & Chairman of the Boardless than a yearUS$3.15m0.028%
$ 80.0k
Rhonda Hellums
Executive VP4.3yrsUS$1.15m0.0011%
$ 3.0k
Steven Romano
Executive VP and Chief Research & Development Officer3.2yrsUS$981.90k0.0092%
$ 26.0k
Marie Lindholm
Chief Scientific Officer2.5yrssin datossin datos
Gem Hopkins
Head of IR & Corporate Communicationsno datasin datossin datos
Jaimin Shah
SVP & General Counselless than a yearsin datossin datos
J.P. Gabriel
Chief Technical Operations Officer3.6yrssin datossin datos
Curtis Rambaran
Chief Medical Officerno datasin datossin datos
2.8yrs
Permanencia media
67yo
Promedio de edad

Equipo directivo experimentado: El equipo directivo de SLN se considera experimentado (2.8 años antigüedad media).


Miembros de la Junta

NombrePosiciónPermanenciaCompensaciónPropiedad
Iain Ross
Interim CEO & Chairman of the Board7.2yrsUS$3.15m0.028%
$ 80.0k
Rhonda Hellums
Executive VPless than a yearUS$1.15m0.0011%
$ 3.0k
Timothy McInerney
Independent Non-Executive Director1.1yrsUS$77.50ksin datos
David Lemus
Independent Non-Executive Director8yrsUS$138.61k0.0053%
$ 15.1k
Gordon Duff
Chairman of Scientific Advisory Board6.3yrssin datossin datos
John Porter
Member of Scientific Advisory Board6.3yrssin datossin datos
James Ede-Golightly
Independent Non-Executive Directorless than a yearUS$236.56k0.011%
$ 30.0k
Henry Ginsberg
Member of Scientific Advisory Board6.3yrssin datossin datos
Annemieke Aartsma-Rus
Member of Scientific Advisory Board6.3yrssin datossin datos
John Whittaker
Member of Scientific Advisory Board6yrssin datossin datos
Tom Brown
Member of Scientific Advisory Board4.4yrssin datossin datos
6.3yrs
Permanencia media
64yo
Promedio de edad

Junta con experiencia: La junta directiva de SLN se considera experimentada (6.3 años de antigüedad promedio).


Análisis de la empresa y estado de los datos financieros

DatosÚltima actualización (huso horario UTC)
Análisis de la empresa2026/06/10 22:50
Precio de las acciones al final del día2026/06/10 00:00
Beneficios2026/03/31
Ingresos anuales2025/12/31

Fuentes de datos

Los datos utilizados en nuestro análisis de empresas proceden de S&P Global Market Intelligence LLC. Los siguientes datos se utilizan en nuestro modelo de análisis para generar este informe. Los datos están normalizados, lo que puede introducir un retraso desde que la fuente está disponible.

PaqueteDatosMarco temporalEjemplo Fuente EE.UU. *
Finanzas de la empresa10 años
  • Cuenta de resultados
  • Estado de tesorería
  • Balance
Estimaciones del consenso de analistas+3 años
  • Previsiones financieras
  • Objetivos de precios de los analistas
Precios de mercado30 años
  • Precios de las acciones
  • Dividendos, escisiones y acciones
Propiedad10 años
  • Accionistas principales
  • Información privilegiada
Gestión10 años
  • Equipo directivo
  • Consejo de Administración
Principales avances10 años
  • Anuncios de empresas

* Ejemplo para valores de EE.UU., para no EE.UU. se utilizan formularios y fuentes normativas equivalentes.

A menos que se especifique lo contrario, todos los datos financieros se basan en un periodo anual, pero se actualizan trimestralmente. Esto se conoce como datos de los últimos doce meses (TTM) o de los últimos doce meses (LTM). Más información.

Modelo de análisis y copo de nieve

Los detalles del modelo de análisis utilizado para generar este informe están disponibles en nuestra página de Github, también tenemos guías sobre cómo utilizar nuestros informes y tutoriales en Youtube.

Conozca al equipo de talla mundial que diseñó y construyó el modelo de análisis Simply Wall St.

Métricas industriales y sectoriales

Simply Wall St calcula cada 6 horas nuestras métricas sectoriales y de sección. Los detalles de nuestro proceso están disponibles en Github.

Fuentes analistas

Silence Therapeutics plc está cubierta por 13 analistas. 6 de esos analistas presentaron las estimaciones de ingresos o ganancias utilizadas como datos para nuestro informe. Las estimaciones de los analistas se actualizan a lo largo del día.

AnalistaInstitución
Howard MillerCanaccord Genuity
Keay NakaeChardan Capital Markets, LLC
Nathaniel CallowayEdison Investment Research