U.S. Pharmaceuticals & Biotech Profitable Climbers

Zevra Therapeutics

Market Cap: US$495.4m

A commercial-stage company, focuses on addressing unmet needs for the treatment of rare diseases in the United States.

Alvotech

Market Cap: US$1.3b

Through its subsidiaries, develops and manufactures biosimilar medicines for patients worldwide.

Corcept Therapeutics

Market Cap: US$3.7b

Engages in discovery and development of medication for the treatment of severe endocrinologic, oncologic, metabolic, and neurologic disorders in the United States.

Alnylam Pharmaceuticals

Market Cap: US$43.7b

Alnylam Pharmaceuticals, Inc. discovers, develops, manufactures, and commercializes therapeutics based on ribonucleic acid interference in the United States, Europe, and internationally.

Kiniksa Pharmaceuticals International

Market Cap: US$3.6b

A biopharmaceutical company, developing and commercializing novel therapies for diseases with unmet need and focuses on cardiovascular indications worldwide.

Emergent BioSolutions

Market Cap: US$574.0m

A life sciences company, provides preparedness and response solutions for accidental, deliberate, and naturally occurring public health threats in the United States.

XOMA Royalty

Market Cap: US$319.6m

Operates as a biotech royalty aggregator in the United States and the Asia Pacific.

Stoke Therapeutics

Market Cap: US$2.0b

An early-stage biopharmaceutical company, engages in the development of treatments for severe genetic diseases by upregulating protein expression.

SIGA Technologies

Market Cap: US$483.4m

A commercial-stage pharmaceutical company, focuses on the health security market in the United States.

BeOne Medicines

Market Cap: US$40.1b

An oncology company, engages in discovering and developing various treatments for cancer patients in the United States, China, Europe, and internationally.

Krystal Biotech

Market Cap: US$7.7b

A commercial-stage biotechnology company, discovers, develops, manufactures, and commercializes genetic medicines to treat diseases with high unmet medical needs in the United States.

Gyre Therapeutics

Market Cap: US$752.6m

A pharmaceutical company, engages in the development and commercialization of small-molecule, anti-inflammatory, and anti-fibrotic drugs targeting organ fibrosis.

Protagonist Therapeutics

Market Cap: US$5.2b

A biopharmaceutical company, develops peptide therapeutics for hematology and blood disorders, and inflammatory and immunomodulatory diseases.

Organon

Market Cap: US$2.1b

Develops and delivers health solutions through prescription therapies and medical devices in the United States, Europe, Canada, Japan, rest of the Asia Pacific, Latin America, the Middle East, Russia, Africa, and internationally.

Abeona Therapeutics

Market Cap: US$285.0m

A clinical-stage biopharmaceutical company, develops gene and cell therapies for life-threatening diseases.

TG Therapeutics

Market Cap: US$4.3b

A commercial stage biopharmaceutical company, focuses on the acquisition, development, and commercialization of novel treatments for B-cell mediated diseases in the United States and internationally.

ADMA Biologics

Market Cap: US$3.8b

A biopharmaceutical company, develops, manufactures, and markets specialty plasma-derived biologics for the treatment of immune deficiencies and infectious diseases in the United States and internationally.

Bausch Health Companies

Market Cap: US$2.3b

Operates as a diversified specialty pharmaceutical and medical device company, develops, manufactures, and markets a range of products primarily in gastroenterology, hepatology, neurology, dermatology, generic pharmaceuticals, over-the-counter (OTC) products, aesthetic medical devices, and eye health in the United States and internationally.

AbbVie

Market Cap: US$397.5b

A research-based biopharmaceutical company, engages in the research and development, manufacturing, commercializing, and sale of medicines and therapies worldwide.

Ligand Pharmaceuticals

Market Cap: US$3.6b

A biopharmaceutical company, develops and licenses biopharmaceutical assets worldwide.

Vericel

Market Cap: US$1.9b

A commercial-stage biopharmaceutical company, engages in the research, development, manufacture, and distribution of cellular therapies and specialty biologic products for sports medicine and severe burn care markets in North America.

ANI Pharmaceuticals

Market Cap: US$1.6b

A biopharmaceutical company, develops, manufactures, and markets branded and generic pharmaceutical products in the United States and internationally.

Repligen

Market Cap: US$7.6b

A life sciences company, develops and commercializes bioprocessing technologies and systems in North America, Europe, the Asia Pacific, and internationally.

Eli Lilly

Market Cap: US$901.9b

Eli Lilly and Company discovers, develops, manufactures, and markets human pharmaceutical products in the United States, Europe, China, Japan, and internationally.

Earth Science Tech

Market Cap: US$35.0m

Together with its subsidies, focuses on health and wellness industry.

Indivior Pharmaceuticals

Market Cap: US$4.2b

Develops, manufactures, and sells buprenorphine-based prescription drugs for the treatment of opioid dependence and related disorders in the United States, Europe, Canada, Australia, and internationally.

Protalix BioTherapeutics

Market Cap: US$246.1m

A biopharmaceutical company, engages in the development, production, and commercialization of recombinant therapeutic proteins based on the ProCellEx plant cell-based protein expression system.

Amneal Pharmaceuticals

Market Cap: US$4.6b

A global biopharmaceutical company, develops, manufactures, markets, and distributes generics, injectables, biosimilars, and specialty branded pharmaceutical products worldwide.

Sotera Health

Market Cap: US$5.0b

Provides sterilization, lab testing, and advisory services for the healthcare industry in the United States, Canada, Europe, and internationally.

MannKind

Market Cap: US$1.7b

A biopharmaceutical company, focuses on the provision of various solutions for transforming chronic disease care.