U.S. Pharmaceuticals & Biotech Big Green Snowflakes

Merck

Market Cap: US$191.3b

Operates as a healthcare company worldwide.

SIGA Technologies

Market Cap: US$435.1m

A commercial-stage pharmaceutical company, focuses on the health security market in the United States.

Royalty Pharma

Market Cap: US$18.3b

Operates as a buyer of biopharmaceutical royalties and a funder of innovation in the biopharmaceutical industry in the United States.

Exelixis

Market Cap: US$11.6b

An oncology company, focuses on the discovery, development, and commercialization of new medicines for difficult-to-treat cancers in the United States.

Johnson & Johnson

Market Cap: US$366.8b

Engages in the research and development, manufacture, and sale of various products in the healthcare field worldwide.

Catalyst Pharmaceuticals

Market Cap: US$3.0b

A commercial-stage biopharmaceutical company, focuses on developing and commercializing medicines for patients living with rare diseases in the United States.

Vericel

Market Cap: US$2.1b

A commercial-stage biopharmaceutical company, engages in the research, development, manufacture, and distribution of cellular therapies and specialty biologic products for sports medicine and severe burn care markets in North America.

Krystal Biotech

Market Cap: US$3.6b

A commercial-stage biotechnology company, discovers, develops, manufactures, and commercializes genetic medicines to treat diseases with high unmet medical needs in the United States.

Eli Lilly

Market Cap: US$645.8b

Eli Lilly and Company discovers, develops, and markets human pharmaceuticals in the United States, Europe, China, Japan, and internationally.

Gilead Sciences

Market Cap: US$134.9b

A biopharmaceutical company, discovers, develops, and commercializes medicines in the areas of unmet medical need in the United States, Europe, and internationally.

Halozyme Therapeutics

Market Cap: US$6.7b

A biopharmaceutical company, researches, develops, and commercializes of proprietary enzymes and devices in the United States and internationally.

Incyte

Market Cap: US$12.6b

A biopharmaceutical company, engages in the discovery, development, and commercialization of therapeutics in the United States, Europe, Canada, and Japan.

Phibro Animal Health

Market Cap: US$993.1m

Operates as an animal health and mineral nutrition company in the United States, Israel, Brazil, Ireland, and internationally.

Bristol-Myers Squibb

Market Cap: US$95.6b

Bristol-Myers Squibb Company discovers, develops, licenses, manufactures, markets, distributes, and sells biopharmaceutical products worldwide.

Applied DNA Sciences

Market Cap: US$3.4m

A biotechnology company, develops and commercializes technologies to produce and detect deoxyribonucleic acid (DNA) in the Americas, Europe, Asia, and internationally.

Harmony Biosciences Holdings

Market Cap: US$1.9b

A commercial-stage pharmaceutical company, focuses on developing and commercializing therapies for patients with rare and other neurological diseases in the United States.

Pfizer

Market Cap: US$131.8b

Pfizer Inc. discovers, develops, manufactures, markets, distributes, and sells biopharmaceutical products in the United States and internationally.

Amgen

Market Cap: US$149.7b

Amgen Inc. discovers, develops, manufactures, and delivers human therapeutics worldwide.

Niagen Bioscience

Market Cap: US$866.7m

Operates as a bioscience company engages in developing healthy aging products.

ACADIA Pharmaceuticals

Market Cap: US$3.7b

A biopharmaceutical company, focuses on the development and commercialization of medicines for central nervous system (CNS) disorders and rare diseases in the United States.

Corcept Therapeutics

Market Cap: US$8.2b

Engages in discovery and development of medication for the treatment of severe endocrinologic, oncologic, metabolic, and neurologic disorders in the United States.

Puma Biotechnology

Market Cap: US$167.3m

A biopharmaceutical company, focuses on the development and commercialization of products to enhance cancer care in the United States and internationally.

CorMedix

Market Cap: US$843.1m

A biopharmaceutical company, focuses on developing and commercializing therapeutic products for life-threatening diseases and conditions in the United States.

CytomX Therapeutics

Market Cap: US$378.1m

Operates as an oncology-focused biopharmaceutical company that focuses on developing novel conditionally activated biologics localized to the tumor microenvironment.

AbbVie

Market Cap: US$323.4b

A research-based biopharmaceutical company, engages in the research and development, manufacture, commercialization, and sale of medicines and therapies worldwide.

Jazz Pharmaceuticals

Market Cap: US$6.6b

Jazz Pharmaceuticals plc identifies, develops, and commercializes pharmaceutical products in the United States, Europe, and internationally.

Avalo Therapeutics

Market Cap: US$38.9m

A clinical stage biotechnology company, focuses on the development of therapies for the treatment of immune dysregulation in the Unites States.

Journey Medical

Market Cap: US$181.8m

Focuses on the development and commercialization of pharmaceutical products for the treatment of dermatological conditions in the United States.

Evaxion

Market Cap: US$16.6m

A clinical-stage biotech company, develops artificial intelligence-powered immunology vaccines.

Protagonist Therapeutics

Market Cap: US$2.8b

A biopharmaceutical company, develops peptide therapeutics for hematology and blood disorders, and inflammatory and immunomodulatory diseases.

Agios Pharmaceuticals

Market Cap: US$1.8b

A biopharmaceutical company, discovers and develops medicines in the field of cellular metabolism in the United States.

Tenaya Therapeutics

Market Cap: US$71.8m

A clinical-stage biotechnology company, discovers, develops, and delivers therapies for heart disease in the United States.

Soleno Therapeutics

Market Cap: US$3.8b

A clinical-stage biopharmaceutical company, focuses on the development and commercialization of novel therapeutics for the treatment of rare diseases.

Qiagen

Market Cap: US$9.6b

Provides sample to insight solutions that transform biological samples into molecular insights in the Netherlands and internationally.

Medpace Holdings

Market Cap: US$8.4b

Provides clinical research-based drug and medical device development services in North America, Europe, and Asia.

Biogen

Market Cap: US$18.7b

Biogen Inc. discovers, develops, manufactures, and delivers therapies for treating neurological and neurodegenerative diseases in the United States, Europe, Germany, Asia, and internationally.