iTeos Therapeutics, Inc.

NasdaqGM:ITOS Lagerbericht

Marktkapitalisierung: US$448.7m

This company has been acquired

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iTeos Therapeutics Management

Management Kriterienprüfungen 2/4

iTeos Therapeutics CEO ist Michel Detheux , ernannt in Aug 2011, hat eine Amtszeit von 13.58 Jahren. Die jährliche Gesamtvergütung beträgt $6.09M , bestehend aus 10.3% Gehalt und 89.7% Boni, einschließlich Aktien und Optionen des Unternehmens. besitzt direkt 0.31% der Aktien des Unternehmens, im Wert von $1.41M . Die durchschnittliche Betriebszugehörigkeit des Managementteams und des Verwaltungsrats beträgt 5.2 Jahre bzw. 4.3 Jahre.

Wichtige Informationen

Michel Detheux

Geschäftsführender

US$6.1m

Gesamtvergütung

Prozentsatz des Geschäftsführergehalts10.33%
Amtszeit als Geschäftsführer14yrs
Eigentum des Geschäftsführers0.3%
Durchschnittliche Amtszeit des Managements5.2yrs
Durchschnittliche Amtszeit der Vorstandsmitglieder4.3yrs

Jüngste Management Updates

Recent updates

Seeking Alpha • Feb 27

iTeos Therapeutics: Decimated By Collateral Events, Good Chances Of Success Nevertheless

Summary iTeos' lead molecule, Belrestotug, shows promising efficacy in trials despite setbacks in the anti-TIGIT space, with significant partnerships and a strong cash position. The stock has suffered due to failures of similar molecules from competitors, but iTeos' data remains positive, attracting major investments. Financially, iTeos has a solid runway with a market cap of $255mn and cash reserves nearly twice that, ensuring stability. Despite risks, the potential market for anti-TIGIT treatments is vast, and iTeos' strategic partnership with GSK positions it for future success. Read the full article on Seeking Alpha
Seeking Alpha • Dec 18

iTeos Therapeutics: A Perhaps Unjustified Decline To End 2024

Summary iTeos Therapeutics, Inc.'s lead candidate, belrestotug, shows promising response rates in lung cancer but faces challenges with increased toxicity and skepticism due to past failures in similar approaches. The company's financial health is strong, with over half a billion dollars in liquid assets and long-term investments, providing a substantial cushion for ongoing projects. Despite shelving inupadenant, the focus remains on belrestotug, with ongoing trials exploring its potential in various cancer indications. Given the promising data and financial runway, I maintain a Buy sentiment on ITOS stock, despite the inherent risks and market pessimism. Read the full article on Seeking Alpha
Analyseartikel • Nov 15

iTeos Therapeutics, Inc. (NASDAQ:ITOS) Third-Quarter Results: Here's What Analysts Are Forecasting For Next Year

iTeos Therapeutics, Inc. ( NASDAQ:ITOS ) shareholders are probably feeling a little disappointed, since its shares fell...
Seeking Alpha • Sep 15

iTeos Therapeutics: ESMO Data Showing Signs Of A Real Win For TIGIT

Summary iTeos Therapeutics' belrestotug shows promising response rates in lung cancer trials, especially when combined with dostarlimab, despite significant safety concerns. Financially, ITOS has over 3 years of cash runway, bolstered by collaboration revenue, supporting its potential to reach critical milestones. The risks include small trial size, potential non-translation of response rates to survival benefits, and high-grade toxicities that could hinder approval. Despite risks, ITOS's market cap of $600 million suggests substantial upside potential if their immunotherapy gains traction, making it a compelling investment thesis. Read the full article on Seeking Alpha
Analyseartikel • Aug 11

Is iTeos Therapeutics (NASDAQ:ITOS) In A Good Position To Deliver On Growth Plans?

We can readily understand why investors are attracted to unprofitable companies. For example, although...
Seeking Alpha • Jul 09

iTeos Therapeutics: Rippling Waves Of TIGIT Pessimism

Summary iTeos Therapeutics is developing an anti-TIGIT molecule for various cancers, partnering with GSK and advancing to late-stage clinical studies. Their main clinical focus is belrestotug, aiming to differentiate from other anti-TIGIT approaches, with positive interim data readouts. Financially, ITOS has a strong balance sheet with significant cash reserves, but faces risks from unproven TIGIT targets and market valuation fluctuations. Read the full article on Seeking Alpha
Analyseartikel • Jan 25

iTeos Therapeutics, Inc. (NASDAQ:ITOS) Looks Inexpensive But Perhaps Not Attractive Enough

With a price-to-sales (or "P/S") ratio of 5.3x iTeos Therapeutics, Inc. ( NASDAQ:ITOS ) may be sending very bullish...
Seeking Alpha • Jan 10

iTeos: Readouts From TIGIT And Adenosine Pathway Inhibitors Makes This A Must Watch

Summary Data readout from phase 2 GALAXIES Lung-201 study, using belrestotug in combination with dostarlimab to treat patients with 1st-line advanced/metastatic NSCLC, expected 2024. The global non-small cell lung cancer market is expected to reach $36.9 billion by 2031. Data readout from phase 2 TIGIT-006 study, using belrestotug in combination with dostarlimab for the treatment of patients with head and neck squamous cell carcinoma, expected 2024. The global head and neck cancer drugs market size is expected to surpass $3.9 billion by 2030. Read the full article on Seeking Alpha
Analyseartikel • May 13

Industry Analysts Just Upgraded Their iTeos Therapeutics, Inc. (NASDAQ:ITOS) Revenue Forecasts By 16%

Celebrations may be in order for iTeos Therapeutics, Inc. ( NASDAQ:ITOS ) shareholders, with the analysts delivering a...
Analyseartikel • Mar 21

Investors Give iTeos Therapeutics, Inc. (NASDAQ:ITOS) Shares A 25% Hiding

iTeos Therapeutics, Inc. ( NASDAQ:ITOS ) shareholders that were waiting for something to happen have been dealt a blow...
Analyseartikel • Aug 12

The Consensus EPS Estimates For iTeos Therapeutics, Inc. (NASDAQ:ITOS) Just Fell Dramatically

The analysts covering iTeos Therapeutics, Inc. ( NASDAQ:ITOS ) delivered a dose of negativity to shareholders today, by...
Seeking Alpha • Aug 10

iTeos Therapeutics GAAP EPS of $0.16 misses by $1.04

iTeos Therapeutics press release (NASDAQ:ITOS): Q2 GAAP EPS of $0.16 misses by $1.04. The company’s cash and cash equivalent position was $791.9 million as of June 30, 2022, as compared to $302.9 million as of June 30, 2021. Cash balance is expected to provide the company runway into 2026..
Seeking Alpha • Jul 27

iTeos Therapeutics: Too Many Unknowns

Today, we put clinical stage oncology concern iTeos Therapeutics, Inc. in the spotlight for the first time. The company has two main oncology assets in development and a big partnership with GlaxoSmithKline. An investment analysis follows in the paragraphs below. Dandelions spring up where cities have been destroyed.”― Marty Rubin Today, we put iTeos Therapeutics, Inc. (ITOS) in the spotlight for the first time. This small cap oncology concern has a major partnership with a large drug maker and has two primary drug candidates under development. An analysis follows below. Seeking Alpha Company Overview iTeos Therapeutics, Inc. is a clinical-stage biopharmaceutical company headquartered just outside of Boston in Watertown, MA. The company also has a research center in Gosselies, Belgium. The firm is focused on the discovery and development of immuno-oncology therapeutics for patients. The stock currently trades around $25.00 a share and came public in the summer of 2020. It was founded in 2013. Its shares have an approximate market value of $900 million. iTeos Therapeutics has two clinical-stage product candidates, EOS-448 and Inupadenant, in development. Both target a key mechanism that inhibits an effective antitumor immune response. March Company Presentation EOS-448: This is an anti-TIGIT human immunoglobulin G1, or IgG1, antibody that the company is developing to inhibit the immunosuppressive activity of TIGIT. TIGIT is a cell surface receptor expressed on multiple immune cells, including CD8+ T cells, natural killer, or NK, cells and T regulatory cells. EOS-448 binds with high affinity to TIGIT, thereby breaking the immunosuppressive interaction between TIGIT and its ligands. It can also activate FcγR on macrophages, dendritic cells and NK cells in the tumor microenvironment. March Company Presentation According to the company website: This activation of these cells augments the anti-tumor immune response but also triggers Antibody Dependent Cellular Cytotoxicity or ADCC response to those cells which expressed the highest levels of TIGIT, the Tregs." EOS-448 is being developed jointly with GlaxoSmithKline (GSK) under a collaboration arrangement reached last Spring (see below section for details). This is the largest of several developmental partnerships the company has sealed. iTeos has initiated several 1b/2a studies around EOS-448 involving four combo therapies and targeting three indications. March Company Presentation It should be noted that Glaxo and iTeos are working together to evaluate how best to proceed with additional clinical development of EOS-448 in light of the recent release regarding the Roche (RHHBY) SKYSCRAPER-01 study which came out in Mid-May and did not meet its primary endpoint. This trial involved another anti-TIGIT program. Enrollment is also underway in a clinical trial evaluating EOS-448 as both a monotherapy and in combination with Bristol Myers Squibb’s (BMY) iberdomide in patients with multiple myeloma, one of several efforts outside the joint development program with Glaxo. The second compound in development is Inupadenant. This compound is designed to inhibit the ATP-adenosine pathway by specifically targeting A2AR. This is the primary adenosine receptor on immune cells with a high affinity for adenosine. This pathway is recognized as a key pathway that modulates immune responses in pathological conditions. March Company Presentation This candidate is in a much earlier stage of development. The company is in the process of initiating a randomized Phase 2 trial mid-year in metastatic non-small cell lung cancer (mNSCLC) to evaluate the combination of inupadenant with chemotherapy compared to standard of care. iTeos is also enrolling patients in a Phase 2a trial evaluating inupadenant in combination with pembrolizumab in PD-1 resistant melanoma. Analyst Commentary & Balance Sheet Four analyst firms including JPMorgan and Wedbush have reissued Buy ratings on the stock since Mid-May. Price targets proffered range from $34 to $52 a share.
Analyseartikel • May 11

News Flash: Analysts Just Made A Captivating Upgrade To Their iTeos Therapeutics, Inc. (NASDAQ:ITOS) Forecasts

Celebrations may be in order for iTeos Therapeutics, Inc. ( NASDAQ:ITOS ) shareholders, with the analysts delivering a...
Analyseartikel • Nov 25

Rainbows and Unicorns: iTeos Therapeutics, Inc. (NASDAQ:ITOS) Analysts Just Became A Lot More Optimistic

Celebrations may be in order for iTeos Therapeutics, Inc. ( NASDAQ:ITOS ) shareholders, with the analysts delivering a...

Analyse der Geschäftsführervergütung

Wie hat sich die Vergütung von Michel Detheux im Vergleich zu den Einnahmen von iTeos Therapeutics verändert?
DatumGesamtvergütungGehaltUnternehmensgewinne
Jun 30 2025n/an/a

-US$202m

Mar 31 2025n/an/a

-US$131m

Dec 31 2024US$6mUS$629k

-US$134m

Sep 30 2024n/an/a

-US$121m

Jun 30 2024n/an/a

-US$108m

Mar 31 2024n/an/a

-US$135m

Dec 31 2023US$6mUS$579k

-US$113m

Sep 30 2023n/an/a

-US$62m

Jun 30 2023n/an/a

-US$28m

Mar 31 2023n/an/a

US$12m

Dec 31 2022US$11mUS$556k

US$97m

Sep 30 2022n/an/a

US$261m

Jun 30 2022n/an/a

US$330m

Mar 31 2022n/an/a

US$298m

Dec 31 2021US$6mUS$525k

US$215m

Sep 30 2021n/an/a

US$15m

Jun 30 2021n/an/a

-US$67m

Mar 31 2021n/an/a

-US$50m

Dec 31 2020US$17mUS$463k

-US$43m

Sep 30 2020n/an/a

-US$35m

Jun 30 2020n/an/a

-US$31m

Mar 31 2020n/an/a

-US$28m

Dec 31 2019US$2mUS$460k

-US$27m

Vergütung im Vergleich zum Markt: MichelDie Gesamtvergütung ($USD6.09M) liegt über dem Durchschnitt von Unternehmen ähnlicher Größe auf dem Markt US ($USD2.59M).

Entschädigung vs. Einkommen: MichelDie Bezüge der Mitarbeiter sind gestiegen, während das Unternehmen unrentabel ist.

Geschäftsführer

Michel Detheux (59 yo)

14yrs
Amtszeit
US$6,085,657
Vergütung

Dr. Michel Detheux, Ph D, has been the Director of Vor Biopharma Inc. since July 16, 2025. He is Chairman of the Board at InnoSkel.He serves as an Independent Chairman at Ona Therapeutics, S.L. since Dece...

Führungsteam

NamePositionAmtszeitVergütungEigentümerschaft
Michel Detheux
President14yrsUS$6.09m0.31%
$ 1.4m
Matthew Call
Chief Operating Officer6yrsUS$2.62m0.21%
$ 953.1k
David Feltquate
Chief Medical Officer1yrUS$5.35m0%
$ 0
Matthew Gall
Chief Financial Officer5.2yrsUS$2.72m0.055%
$ 247.9k
Yvonne McGrath
Chief Scientific Officer3.6yrskeine Datenkeine Daten
Adi Osovsky
Executive Vice President of Legal2.6yrskeine Datenkeine Daten
Philippe Brantegem
Chief People Officer5.6yrskeine Datenkeine Daten
5.2yrs
Durchschnittliche Betriebszugehörigkeit
51.5yo
Durchschnittliches Alter

Erfahrenes Management: Das Managementteam von ITOS ist erfahren und erfahren (durchschnittliche Amtszeit von 5.2 Jahren).

Vorstandsmitglieder

NamePositionAmtszeitVergütungEigentümerschaft
Michel Detheux
President13.6yrsUS$6.09m0.31%
$ 1.4m
Ann Rhoads
Independent Director5.2yrsUS$345.57k0%
$ 0
David Hallal
Independent Chairman of the Board7.2yrsUS$442.82k0%
$ 0
Matthew Vander Heiden
Member of Scientific Advisory Boardno datakeine Datenkeine Daten
Jill DeSimone
Independent Director1.4yrsUS$686.27k0%
$ 0
Tony W. Ho
Independent Director4.3yrsUS$332.76k0%
$ 0
Robert Iannone
Independent Director4.3yrsUS$341.26k0%
$ 0
David Lee
Independent Director1.7yrsUS$320.07k0%
$ 0
Gordon Freeman
Chairman of Scientific Advisory Boardno datakeine Datenkeine Daten
Benoit Van den Eynde
Member of Scientific Advisory Boardno datakeine Datenkeine Daten
Florent Ginhoux
Member of Scientific Advisory Boardno datakeine Datenkeine Daten
Roberta Zappasodi
Member of Scientific Advisory Boardno datakeine Datenkeine Daten
4.3yrs
Durchschnittliche Betriebszugehörigkeit
59yo
Durchschnittliches Alter

Erfahrener Vorstand: ITOSDie Vorstandsmitglieder gelten als erfahren (4.3 Jahre durchschnittliche Amtszeit).

Unternehmensanalyse und Finanzdaten Status

DatenZuletzt aktualisiert (UTC-Zeit)
Unternehmensanalyse2025/08/30 17:17
Aktienkurs zum Tagesende2025/08/28 00:00
Gewinne2025/06/30
Jährliche Einnahmen2024/12/31

Datenquellen

Die in unserer Unternehmensanalyse verwendeten Daten stammen von S&P Global Market Intelligence LLC. Die folgenden Daten werden in unserem Analysemodell verwendet, um diesen Bericht zu erstellen. Die Daten sind normalisiert, was zu einer Verzögerung bei der Verfügbarkeit der Quelle führen kann.

PaketDatenZeitrahmenBeispiel US-Quelle *
Finanzdaten des Unternehmens10 Jahre
  • Gewinn- und Verlustrechnung
  • Kapitalflussrechnung
  • Bilanz
Konsensschätzungen der Analysten+3 Jahre
  • Finanzielle Vorausschau
  • Kursziele der Analysten
Marktpreise30 Jahre
  • Aktienkurse
  • Dividenden, Splits und Aktionen
Eigentümerschaft10 Jahre
  • Top-Aktionäre
  • Insiderhandel
Verwaltung10 Jahre
  • Das Führungsteam
  • Direktorium
Wichtige Entwicklungen10 Jahre
  • Ankündigungen des Unternehmens

* Beispiel für US-Wertpapiere, für nicht-US-amerikanische Wertpapiere werden gleichwertige regulatorische Formulare und Quellen verwendet.

Sofern nicht anders angegeben, beziehen sich alle Finanzdaten auf einen Jahreszeitraum, werden aber vierteljährlich aktualisiert. Dies wird als Trailing Twelve Month (TTM) oder Last Twelve Month (LTM) Daten bezeichnet. Erfahren Sie mehr.

Analysemodell und Schneeflocke

Einzelheiten zu dem Analysemodell, mit dem dieser Bericht erstellt wurde, finden Sie auf unserer Github-Seite. Außerdem bieten wir Leitfäden zur Verwendung unserer Berichte und Tutorials auf YouTube an.

Erfahren Sie mehr über das Weltklasse-Team, das das Simply Wall St-Analysemodell entworfen und entwickelt hat.

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Analysten-Quellen

iTeos Therapeutics, Inc. wird von 3 Analysten beobachtet. 5 dieser Analysten hat die Umsatz- oder Gewinnschätzungen übermittelt, die als Grundlage für unseren Bericht dienen. Die von den Analysten übermittelten Daten werden im Laufe des Tages aktualisiert.

AnalystEinrichtung
Michael UlzBaird
Derek ArchilaWells Fargo Securities, LLC
Eva Fortea-VerdejoWells Fargo Securities, LLC