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MeiraGTx Holdings plcNasdaqGS:MGTX Stock Report

Market Cap US$1.3b
Share Price
n/a
1Y85.0%
7D10.3%
1D-5.3%
Portfolio Value
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MeiraGTx Holdings plc

NasdaqGS:MGTX Stock Report

Market Cap: US$1.3b

MeiraGTx Holdings (MGTX) Stock Overview

A clinical-stage genetic medicines company, focusing on developing treatments for patients with serious diseases. More details

MGTX fundamental analysis
Snowflake Score
Valuation1/6
Future Growth2/6
Past Performance0/6
Financial Health2/6
Dividends0/6

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MeiraGTx Holdings plc Competitors

Price History & Performance

Summary of share price highs, lows and changes for MeiraGTx Holdings
Historical stock prices
Current Share PriceUS$12.80
52 Week HighUS$13.63
52 Week LowUS$6.45
Beta1.26
1 Month Change30.61%
3 Month Change39.43%
1 Year Change84.97%
3 Year Change84.17%
5 Year Change-16.12%
Change since IPO-14.67%

Recent News & Updates

Analysis Article May 18

MeiraGTx Holdings plc (NASDAQ:MGTX) First-Quarter Results: Here's What Analysts Are Forecasting For This Year

As you might know, MeiraGTx Holdings plc ( NASDAQ:MGTX ) last week released its latest quarterly, and things did not...

Recent updates

Analysis Article May 18

MeiraGTx Holdings plc (NASDAQ:MGTX) First-Quarter Results: Here's What Analysts Are Forecasting For This Year

As you might know, MeiraGTx Holdings plc ( NASDAQ:MGTX ) last week released its latest quarterly, and things did not...
Seeking Alpha Apr 15

MeiraGTx: Turning Dry Mouth Into Liquid Gold

Summary MeiraGTx is approaching a pivotal Phase 1 data readout for AAV-hAQP1 in radiation-induced xerostomia, with the stock recently hitting 52-week highs. MGTX's riboswitch-controlled gene therapy platform, vertical integration, and big pharma partnerships differentiate its approach and support an ambitious pipeline. I estimate AAV2hAQP1's peak sales at ~$1.2B, with risk-adjusted NPV of $979.8M, and see tomorrow’s data as a major de-risking event. Despite financial flexibility from collaborations and credit amendments, MGTX may need an equity raise within the next six quarters. Read the full article on Seeking Alpha
Analysis Article Apr 01

What Does The Future Hold For MeiraGTx Holdings plc (NASDAQ:MGTX)? These Analysts Have Been Cutting Their Estimates

Market forces rained on the parade of MeiraGTx Holdings plc ( NASDAQ:MGTX ) shareholders today, when the analysts...
Analysis Article Mar 30

MeiraGTx Holdings plc (NASDAQ:MGTX) Analysts Are Cutting Their Estimates: Here's What You Need To Know

MeiraGTx Holdings plc ( NASDAQ:MGTX ) just released its latest annual results and things are looking bullish. The...
Analysis Article Nov 17

Analysts Have Lowered Expectations For MeiraGTx Holdings plc (NASDAQ:MGTX) After Its Latest Results

It's shaping up to be a tough period for MeiraGTx Holdings plc ( NASDAQ:MGTX ), which a week ago released some...
Analysis Article Oct 22

MeiraGTx Holdings (NASDAQ:MGTX) Is Making Moderate Use Of Debt

David Iben put it well when he said, 'Volatility is not a risk we care about. What we care about is avoiding the...
Analysis Article Sep 23

There's Reason For Concern Over MeiraGTx Holdings plc's (NASDAQ:MGTX) Price

You may think that with a price-to-sales (or "P/S") ratio of 17.2x MeiraGTx Holdings plc ( NASDAQ:MGTX ) is a stock to...
Analysis Article Aug 20

News Flash: Analysts Just Made A Captivating Upgrade To Their MeiraGTx Holdings plc (NASDAQ:MGTX) Forecasts

NasdaqGS:MGTX 1 Year Share Price vs Fair Value Explore MeiraGTx Holdings's Fair Values from the Community and select...
Analysis Article Jul 04

Would MeiraGTx Holdings (NASDAQ:MGTX) Be Better Off With Less Debt?

Warren Buffett famously said, 'Volatility is far from synonymous with risk.' So it seems the smart money knows that...
Analysis Article May 29

Some Confidence Is Lacking In MeiraGTx Holdings plc (NASDAQ:MGTX) As Shares Slide 25%

MeiraGTx Holdings plc ( NASDAQ:MGTX ) shareholders that were waiting for something to happen have been dealt a blow...
Analysis Article Apr 04

Is MeiraGTx Holdings (NASDAQ:MGTX) Using Debt Sensibly?

Howard Marks put it nicely when he said that, rather than worrying about share price volatility, 'The possibility of...
Seeking Alpha Mar 25

MeiraGTx Holdings: Gaining Regulatory Focus

Summary MeiraGTx (MGTX) develops gene therapies for ocular diseases, Parkinson’s Disease, and xerostomia, with multiple assets in advanced clinical stages showing promising efficacy and safety data. MGTX uses AAV5 capsid vectors and riboswitch technology to deliver gene therapies, aiming for safer and more controlled treatments compared to earlier approaches. Financially, MGTX has a strong cash position bolstered by a $200mn deal with Hologen, providing a substantial runway for continued development. Despite a diverse pipeline and long timelines to approval, positive clinical outcomes suggest potential for multiple approvals within the next 18 months, making MGTX a cautious buy. Read the full article on Seeking Alpha
Analysis Article Mar 14

MeiraGTx Holdings plc's (NASDAQ:MGTX) 29% Price Boost Is Out Of Tune With Revenues

The MeiraGTx Holdings plc ( NASDAQ:MGTX ) share price has done very well over the last month, posting an excellent gain...
Seeking Alpha Jan 22

MeiraGTx: 2 Possible Near-Term BLA Filings Could Ignite Shareholder Value

Summary MeiraGTx Holdings plc is advancing AAV-AIPL1 for AIPL1-associated Leber congenital amaurosis 4, with a near-term BLA filing in the UK under Exceptional Circumstance possible. Bota-vec, developed with Janssen, could see a BLA filing for X-linked Retinitis Pigmentosa in 2025. Initiation of phase 3 study, using AAV-GAD for the treatment of patients with Parkinson's Disease, expected in 2025. MeiraGTx's financials show $125 million in cash, but additional funding will be needed within the next 12 months. Read the full article on Seeking Alpha
Analysis Article Nov 15

Analysts Have Lowered Expectations For MeiraGTx Holdings plc (NASDAQ:MGTX) After Its Latest Results

Last week, you might have seen that MeiraGTx Holdings plc ( NASDAQ:MGTX ) released its third-quarter result to the...
Seeking Alpha Oct 15

MeiraGTx: Positive PD Data Moves Needle Forward For Regulatory Meetings

Summary MeiraGTx Holdings plc's GAD gene therapy for Parkinson's Disease shows promising phase 1/2 results, with significant improvements in UPDRS Part 3 and PDQ-39 scores. The company plans to discuss phase 3 study designs with regulatory agencies in Q4 2024, potentially initiating late-stage studies in 2025. MeiraGTx secured $50 million in funding, including a $30 million equity investment from Sanofi, enhancing its financial stability for future developments. With multiple regulatory filings expected annually through 2027, MeiraGTx's diverse pipeline offers significant potential for long-term investor gains. Read the full article on Seeking Alpha
Seeking Alpha Jul 15

MeiraGTx: A Very Attractive Longer-Term Play, With Potential Near-Term Catalysts

Summary Bota-vec sale to JNJ/Janssen is complete – cash & future milestones from the deal should carry MeiraGTx through the next catalysts. The partnership with Sanofi strengthens the balance sheet and helps validate technology platforms. MGTX is no longer just an ocular GTx (gene therapy) company - its GTx for radiation-induced xerostomia has a high potential for success. Riboswitch gene regulation platform R&D Day in 2H'24 could provide significant upside through future lucrative collaborations. The price at $4.61/s or ~$296M valuation = Long-term Buy because I can see a path for a 3-5x pop over the next 12–18 months. Read the full article on Seeking Alpha
Analysis Article Jun 19

MeiraGTx Holdings (NASDAQ:MGTX) Has Debt But No Earnings; Should You Worry?

David Iben put it well when he said, 'Volatility is not a risk we care about. What we care about is avoiding the...
Seeking Alpha Feb 15

MeiraGTx: Bota-Vec Program Advancing With Milestones Being Met

Summary Positive results achieved in phase 1/2 MGT009 study using bota-vec for the treatment of patients with XLRP; Patients given this gene therapy achieved meaningful improvement of vision. Enrollment completed in ongoing phase 3 LUMEOS study, using bota-vec for the treatment of patients with XLRP; Potential results could be released end of 2024 or in early 2025. The global Retinitis Pigmentosa market size is expected to reach $20.47 billion by 2029; It is said that 10% to 15% of RP patients have XLRP. MeiraGTx established asset purchase agreement with Johnson & Johnson whereby it would be entitled to receive upfront cash payment of $130 million and be eligible to earn up to $285 million in milestone payments. Read the full article on Seeking Alpha
Analysis Article Sep 08

Does MeiraGTx Holdings (NASDAQ:MGTX) Have A Healthy Balance Sheet?

David Iben put it well when he said, 'Volatility is not a risk we care about. What we care about is avoiding the...
Analysis Article Apr 11

Calculating The Intrinsic Value Of MeiraGTx Holdings plc (NASDAQ:MGTX)

Key Insights MeiraGTx Holdings' estimated fair value is US$5.46 based on 2 Stage Free Cash Flow to Equity Current share...
Analysis Article Mar 16

MeiraGTx Holdings plc (NASDAQ:MGTX) Analysts Are Reducing Their Forecasts For This Year

One thing we could say about the analysts on MeiraGTx Holdings plc ( NASDAQ:MGTX ) - they aren't optimistic, having...

Shareholder Returns

MGTXUS BiotechsUS Market
7D10.3%5.1%1.9%
1Y85.0%40.0%20.3%

Return vs Industry: MGTX exceeded the US Biotechs industry which returned 40% over the past year.

Return vs Market: MGTX exceeded the US Market which returned 20.3% over the past year.

Price Volatility

Is MGTX's price volatile compared to industry and market?
MGTX volatility
MGTX Average Weekly Movement10.5%
Biotechs Industry Average Movement10.5%
Market Average Movement7.3%
10% most volatile stocks in US Market16.8%
10% least volatile stocks in US Market3.1%

Stable Share Price: MGTX has not had significant price volatility in the past 3 months compared to the US market.

Volatility Over Time: MGTX's weekly volatility (11%) has been stable over the past year.

About the Company

FoundedEmployeesCEOWebsite
2015409Alexandria Forbeswww.meiragtx.com

MeiraGTx Holdings plc, a clinical-stage genetic medicines company, focusing on developing treatments for patients with serious diseases. The company develops various therapies for ocular diseases, including inherited retinal diseases and large degenerative ocular diseases; neurodegenerative diseases; and xerostomia. It is also develops AAV-AQP1 for radiation-induced grade 2/3 radiation-induced xerostomia, as well as for Sjogren’s syndrome; AAV-GAD in Phase 2 trial for Parkinson’s disease; AAV-RPE65 in Phase 2 trial for RPE65-associated retinal dystrophy; and AAV-CNGB3 and AAV-CNGA3, which are both in Phase ½ clinical trial for achromatopsia, as well as offers AAV-AIPL1 for Leber congenital amaurosis (LCA) 4.

MeiraGTx Holdings plc Fundamentals Summary

How do MeiraGTx Holdings's earnings and revenue compare to its market cap?
MGTX fundamental statistics
Market capUS$1.25b
Earnings (TTM)-US$120.53m
Revenue (TTM)US$79.76m
14.9x
P/S Ratio
-9.8x
P/E Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
MGTX income statement (TTM)
RevenueUS$79.76m
Cost of RevenueUS$3.66m
Gross ProfitUS$76.10m
Other ExpensesUS$196.63m
Earnings-US$120.53m

Last Reported Earnings

Mar 31, 2026

Next Earnings Date

n/a

Earnings per share (EPS)-1.30
Gross Margin95.41%
Net Profit Margin-151.12%
Debt/Equity Ratio-128.3%

How did MGTX perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/07/01 21:55
End of Day Share Price 2026/07/01 00:00
Earnings2026/03/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

MeiraGTx Holdings plc is covered by 17 analysts. 7 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Huidong WangBarclays
Alec StranahanBofA Global Research
Gbolahan Amusa BenzChardan Capital Markets, LLC