Spruce Biosciences Ownership

Who are the major shareholders and have insiders been buying or selling?

Recent Insider Transactions

NasdaqGS:SPRB Recent Insider Transactions by Companies or Individuals
Date	Value	Name	Entity	Shares	Max Price
27 Mar 24	SellUS$781,730	Novo Holdings A/S	Company	1,100,000	US$0.72
25 Mar 24	SellUS$1,057,405	Novo Holdings A/S	Company	1,450,000	US$0.74
21 Mar 24	SellUS$350,951	Novo Holdings A/S	Company	465,021	US$0.75
20 Mar 24	SellUS$1,358,804	Novo Holdings A/S	Company	1,794,999	US$0.77
14 Mar 24	SellUS$1,698,902	Novo Holdings A/S	Company	1,912,316	US$0.89
14 Mar 24	SellUS$1,698,902	Novo Holdings A/S	Company	1,912,316	US$0.89

Insider Buying: Insufficient data to determine if insiders have bought more shares than they have sold in the past 3 months.

Dilution of Shares: Shareholders have been diluted in the past year, with total shares outstanding growing by 3.5%.

Top 25 shareholders own 78.14% of the company

Ownership	Name	Shares	Current Value	Change %	Portfolio %
7.24%	Odlander, Fredrikson & Co. AB	2,977,621	US$2.1m	0%	0.8%
7.14%	RiverVest Venture Management LLC	2,936,281	US$2.1m	0%	25.94%
7.04%	Abingworth LLP	2,896,518	US$2.1m	0%	0.62%
6.86%	Bradley Radoff	2,825,000	US$2.0m	0%	no data
6.34%	Rock Springs Capital Management LP	2,609,125	US$1.8m	0%	0.05%
5.74%	5AM Venture Management, LLC	2,364,000	US$1.7m	0%	0.34%
5.42%	Armistice Capital LLC	2,230,000	US$1.6m	0%	0.04%
5.25%	Omega Fund Management, LLC	2,161,022	US$1.5m	0%	1.05%
5.16%	Aigh Capital Management, LLC	2,123,863	US$1.5m	75.4%	0.61%
4.37%	Niall O'Donnell	1,799,105	US$1.3m	0%	no data
3.67%	Rosalind Advisors, Inc.	1,508,419	US$1.1m	-4.92%	0.99%
2.93%	Aisling Capital Management LP	1,205,511	US$853.5k	0%	0.35%
2%	The Vanguard Group, Inc.	822,390	US$582.3k	151%	no data
1.91%	Sands Capital Ventures, LLC	787,007	US$557.2k	0%	0.17%
1.33%	Dafna Capital Management, LLC	548,510	US$388.3k	-3.79%	0.09%
1.24%	Millennium Management LLC	510,441	US$361.4k	-12.5%	no data
0.97%	Alyeska Investment Group, L.P.	400,000	US$283.2k	-60%	no data
0.67%	Acuitas Investments, LLC	275,085	US$194.8k	0.03%	0.07%
0.63%	BlackRock, Inc.	261,016	US$184.8k	0.97%	no data
0.49%	Samir Gharib	202,776	US$143.6k	0%	no data
0.45%	Renaissance Technologies LLC	185,100	US$131.1k	-10.9%	no data
0.41%	Geode Capital Management, LLC	167,404	US$118.5k	0%	no data
0.33%	Two Sigma Investments, LP	134,357	US$95.1k	-8.82%	no data
0.29%	Superstring Capital Management LP	118,814	US$84.1k	0%	0.08%
0.26%	Citadel Advisors LLC	108,240	US$76.6k	44.3%	no data