Orchard Therapeutics Valuation

Is ORTX undervalued compared to its fair value, analyst forecasts and its price relative to the market?

Valuation Score

1/6

Valuation Score 1/6

Below Fair Value
Significantly Below Fair Value
Price-To-Sales vs Peers
Price-To-Sales vs Industry
Price-To-Sales vs Fair Ratio
Analyst Forecast

Share Price vs Fair Value

What is the Fair Price of ORTX when looking at its future cash flows? For this estimate we use a Discounted Cash Flow model.

Below Fair Value: ORTX ($16.7) is trading above our estimate of fair value ($5.18)

Significantly Below Fair Value: ORTX is trading above our estimate of fair value.

Key Valuation Metric

Which metric is best to use when looking at relative valuation for ORTX?

Key metric: As ORTX is unprofitable we use its Price-To-Sales Ratio for relative valuation analysis.

The above table shows the Price to Sales ratio for ORTX. This is calculated by dividing ORTX's market cap by their current revenue.
What is ORTX's PS Ratio?
PS Ratio	17.4x
Sales	US$21.84m
Market Cap	US$380.12m

ORTX key valuation metrics and ratios. From Price to Earnings, Price to Sales and Price to Book to Price to Earnings Growth Ratio, Enterprise Value and EBITDA.
Key Statistics
Enterprise Value/Revenue	13.9x
Enterprise Value/EBITDA	-3x
PEG Ratio	n/a

Price to Sales Ratio vs Peers

How does ORTX's PS Ratio compare to its peers?

The above table shows the PS ratio for ORTX vs its peers. Here we also display the market cap and forecasted growth for additional consideration.
Company	Forward PS	Estimated Growth	Market Cap
Peer Average	27.9x
TSHA Taysha Gene Therapies	38.2x	57.3%	US$379.1m
PRQR ProQR Therapeutics	14.1x	31.9%	US$271.4m
OCGN Ocugen	48x	74.5%	US$225.6m
FHTX Foghorn Therapeutics	11.2x	17.2%	US$285.7m
ORTX Orchard Therapeutics	17.4x	34.5%	US$380.1m

Price-To-Sales vs Peers: ORTX is good value based on its Price-To-Sales Ratio (17.4x) compared to the peer average (20.2x).

Price to Sales Ratio vs Industry

How does ORTX's PS Ratio compare vs other companies in the US Biotechs Industry?

134 Companies	Price / Sales	Estimated Growth	Market Cap
BIIB Biogen	2.2x	1.3%	US$21.34b
MRNA Moderna	3x	5.8%	US$15.16b
INCY Incyte	3.3x	8.9%	US$13.26b
ALKS Alkermes	3.2x	-0.7%	US$4.81b

134 Companies		Estimated Growth	Market Cap

No more companies

Price-To-Sales vs Industry: ORTX is expensive based on its Price-To-Sales Ratio (17.4x) compared to the US Biotechs industry average (13.1x).

Price to Sales Ratio vs Fair Ratio

What is ORTX's PS Ratio compared to its Fair PS Ratio? This is the expected PS Ratio taking into account the company's forecast earnings growth, profit margins and other risk factors.

ORTX PS Ratio vs Fair Ratio.
Fair Ratio
Current PS Ratio	17.4x
Fair PS Ratio	0.2x

Price-To-Sales vs Fair Ratio: ORTX is expensive based on its Price-To-Sales Ratio (17.4x) compared to the estimated Fair Price-To-Sales Ratio (0.2x).

Analyst Price Targets

What is the analyst 12-month forecast and do we have any statistical confidence in the consensus price target?

Analyst Forecast: Insufficient data to show price forecast.

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Company Analysis and Financial Data Status

Data	Last Updated (UTC time)
Company Analysis	2024/01/24 10:05
End of Day Share Price	2024/01/24 00:00
Earnings	2023/09/30
Annual Earnings	2022/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

Package	Data	Timeframe	Example US Source ^*
Company Financials	10 years	Income statement Cash flow statement Balance sheet	SEC Form 10-K SEC Form 10-Q
Analyst Consensus Estimates	+3 years	Forecast financials Analyst price targets	Analyst Research Reports Blue Matrix
Market Prices	30 years	Stock prices Dividends, Splits and Actions	ICE Market Data SEC Form S-1
Ownership	10 years	Top shareholders Insider trading	SEC Form 4 SEC Form 13D
Management	10 years	Leadership team Board of directors	SEC Form 10-K SEC Form DEF 14A
Key Developments	10 years	Company announcements	SEC Form 8-K

^* example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more here.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on .

Analyst Sources

Orchard Therapeutics plc is covered by 10 analysts. 3 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

Analyst	Institution
Charles Duncan	Cantor Fitzgerald & Co.
Emma Nealon	Cantor Fitzgerald & Co.
Graig Suvannavejh	Goldman Sachs