Stock Analysis

Assessing Nektar Therapeutics (NKTR) Valuation Following Recent Share Price Surge

Nektar Therapeutics (NKTR) has caught some attention lately as investors review its share performance over the past few months. The company’s returns have fluctuated recently, which has drawn interest from market watchers tracking new trends in biotech.

See our latest analysis for Nektar Therapeutics.

Zooming out beyond this week’s swings, Nektar’s share price has soared 276.6% year-to-date, with the rally really catching momentum in the last quarter as the 90-day share price return hit an impressive 88.6%. Despite the sharp gains, long-term total shareholder returns remain mixed, reminding investors to weigh both growth potential and risk as the story develops.

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With such dramatic recent gains, the key question is whether Nektar’s current share price still offers upside for investors or if the market has already priced in all the company’s future growth potential.
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Most Popular Narrative: 42% Undervalued

Compared to its last close of $54.28, Nektar Therapeutics is seen in this narrative as trading well below its calculated fair value of $93.86. This highlights a bold case for investors who believe the company can deliver on its future milestones and growth projections.

Strong initial Phase IIb and ongoing data for REZPEG in atopic dermatitis, combined with a large and growing addressable market (expected to reach nearly $30B by 2033), position Nektar to access significant new revenue streams and improve long-term earnings as the population ages and chronic inflammatory diseases rise globally.

Read the complete narrative.

Curious what ambitious financial leaps power this valuation? The narrative hinges on game-changing assumptions for future growth, margins, and a profit turnaround that defies sector norms. Want to see the numbers behind this optimism? Unlock the full story to spot exactly what could trigger the next surge.

Result: Fair Value of $93.86 (UNDERVALUED)

Have a read of the narrative in full and understand what's behind the forecasts.

However, setbacks in key clinical trials or unfavorable litigation outcomes could quickly dampen investor optimism and challenge the bullish case for Nektar.

Find out about the key risks to this Nektar Therapeutics narrative.

Another View: Reality Check on Sales Multiples

While fair value estimates imply Nektar Therapeutics is undervalued, the company's price-to-sales ratio is a hefty 17.6x. This is more than double the peer average of 7.5x and over four times the US pharmaceuticals industry average of 4x. Even compared to the fair ratio of 8.5x, shares appear expensive, which suggests today's optimism may already be factoring in a significant amount of future success.

See what the numbers say about this price — find out in our valuation breakdown.

NasdaqCM:NKTR PS Ratio as at Nov 2025
NasdaqCM:NKTR PS Ratio as at Nov 2025

Build Your Own Nektar Therapeutics Narrative

If you'd rather take the data into your own hands or bring a fresh perspective, you can build your own narrative in just a few minutes. Do it your way

A great starting point for your Nektar Therapeutics research is our analysis highlighting 3 key rewards and 4 important warning signs that could impact your investment decision.

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This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.

Valuation is complex, but we're here to simplify it.

Discover if Nektar Therapeutics might be undervalued or overvalued with our detailed analysis, featuring fair value estimates, potential risks, dividends, insider trades, and its financial condition.

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