Milestone Pharmaceuticals Inc.

NasdaqGS:MIST Stock Report

Market Cap: US$179.6m

Milestone Pharmaceuticals Past Earnings Performance

Past criteria checks 0/6

Milestone Pharmaceuticals's earnings have been declining at an average annual rate of -6%, while the Pharmaceuticals industry saw earnings growing at 10.7% annually. Revenues have been declining at an average rate of 57% per year.

Key information

-5.96%

Earnings growth rate

9.56%

EPS growth rate

Pharmaceuticals Industry Growth5.95%
Revenue growth rate-56.97%
Return on equity-189.64%
Net Margin-3,832.01%
Last Earnings Update31 Mar 2026

Recent past performance updates

Recent updates

Seeking Alpha Jun 09

Milestone Pharmaceuticals: Here Comes The Revenue Ramp

Summary Milestone Pharmaceuticals Inc. remains a Strong Buy, despite recent volatility and a 37% stock decline since FDA approval of Cardamyst. Cardamyst’s rapid-acting efficacy, expanding insurance coverage, and unique market position underpin a compelling medium-term ramp in prescriptions and revenue. International expansion and a Phase 3 trial for AFib-RVR could significantly enlarge MIST’s addressable market and long-term growth prospects. With net cash, de-risked execution, and negativity priced in, positive insurance or revenue catalysts could drive a sharp MIST stock rebound. Read the full article on Seeking Alpha
New Narrative Apr 18

FDA Approval And Shift To Self Administered Care Will Reshape This Cardiovascular Opportunity

Catalysts About Milestone Pharmaceuticals Milestone Pharmaceuticals is a cardiovascular focused company centered on CARDAMYST, an etripamil nasal spray for on demand treatment of paroxysmal supraventricular tachycardia in adults. What are the underlying business or industry changes driving this perspective?
New Narrative Apr 04

Payer Constraints On Self Administered PSVT Care Will Challenge Near Term Progress Yet Offer Upside

Catalysts About Milestone Pharmaceuticals Milestone Pharmaceuticals is a cardiovascular-focused biopharmaceutical company with an FDA approved, self-administered intranasal therapy, CARDAMYST, for acute treatment of paroxysmal supraventricular tachycardia in adults. What are the underlying business or industry changes driving this perspective?
New Narrative Mar 21

Acute Cardiovascular Self Administration Will Reshape Treatment Patterns And Support Long Term Thesis

Catalysts About Milestone Pharmaceuticals Milestone Pharmaceuticals is a biopharmaceutical company focused on developing and commercializing therapies for acute cardiovascular conditions, including paroxysmal supraventricular tachycardia through its intranasal etripamil product, CARDAMYST. What are the underlying business or industry changes driving this perspective?
Analysis Article Nov 15

Does Milestone Pharmaceuticals (NASDAQ:MIST) Have A Healthy Balance Sheet?

David Iben put it well when he said, 'Volatility is not a risk we care about. What we care about is avoiding the...
Analysis Article Nov 06

Does Milestone Pharmaceuticals (NASDAQ:MIST) Have A Healthy Balance Sheet?

Legendary fund manager Li Lu (who Charlie Munger backed) once said, 'The biggest investment risk is not the volatility...
Analysis Article Jun 07

Here's Why Shareholders Should Examine Milestone Pharmaceuticals Inc.'s (NASDAQ:MIST) CEO Compensation Package More Closely

Key Insights Milestone Pharmaceuticals' Annual General Meeting to take place on 13th of June CEO Joe Oliveto's total...
Analysis Article Sep 13

Is Milestone Pharmaceuticals (NASDAQ:MIST) A Risky Investment?

The external fund manager backed by Berkshire Hathaway's Charlie Munger, Li Lu, makes no bones about it when he says...
Analysis Article Mar 07

We're Keeping An Eye On Milestone Pharmaceuticals' (NASDAQ:MIST) Cash Burn Rate

We can readily understand why investors are attracted to unprofitable companies. For example, although Amazon.com made...
Analysis Article Oct 15

We're Keeping An Eye On Milestone Pharmaceuticals' (NASDAQ:MIST) Cash Burn Rate

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although...
Analysis Article Jun 24

We Think Milestone Pharmaceuticals (NASDAQ:MIST) Can Afford To Drive Business Growth

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although...
Analysis Article Feb 25

We're Hopeful That Milestone Pharmaceuticals (NASDAQ:MIST) Will Use Its Cash Wisely

We can readily understand why investors are attracted to unprofitable companies. For example, although...
Analysis Article Aug 25

We're Interested To See How Milestone Pharmaceuticals (NASDAQ:MIST) Uses Its Cash Hoard To Grow

Just because a business does not make any money, does not mean that the stock will go down. For example, biotech and...
Analysis Article Apr 02

Companies Like Milestone Pharmaceuticals (NASDAQ:MIST) Are In A Position To Invest In Growth

We can readily understand why investors are attracted to unprofitable companies. By way of example, Milestone...
Analysis Article Jan 15

What You Need To Know About Milestone Pharmaceuticals Inc.'s (NASDAQ:MIST) Investor Composition

A look at the shareholders of Milestone Pharmaceuticals Inc. ( NASDAQ:MIST ) can tell us which group is most powerful...

Revenue & Expenses Breakdown

How Milestone Pharmaceuticals makes and spends money. Based on latest reported earnings, on an LTM basis.


Earnings and Revenue History

NasdaqGS:MIST Revenue, expenses and earnings (USD Millions)
DateRevenueEarningsG+A ExpensesR&D Expenses
31 Mar 262-685116
31 Dec 252-634618
30 Sep 250-584117
30 Jun 250-563817
31 Mar 250-523616
31 Dec 240-422814
30 Sep 240-432816
30 Jun 240-483119
31 Mar 240-553224
31 Dec 231-603131
30 Sep 235-592936
30 Jun 236-592739
31 Mar 236-592641
31 Dec 225-582540
30 Sep 222-622468
30 Jun 220-622240
31 Mar 2215-442139
31 Dec 2115-431939
30 Sep 2115-351634
30 Jun 2115-321653
31 Mar 210-461531
31 Dec 200-501634
30 Sep 200-601814
30 Jun 200-601824
31 Mar 200-611846
31 Dec 190-551642
30 Sep 190-471435
30 Jun 190-401229
31 Mar 190-29922
31 Dec 180-23717

Quality Earnings: MIST is currently unprofitable.

Growing Profit Margin: MIST is currently unprofitable.


Free Cash Flow vs Earnings Analysis


Past Earnings Growth Analysis

Earnings Trend: MIST is unprofitable, and losses have increased over the past 5 years at a rate of 6% per year.

Accelerating Growth: Unable to compare MIST's earnings growth over the past year to its 5-year average as it is currently unprofitable

Earnings vs Industry: MIST is unprofitable, making it difficult to compare its past year earnings growth to the Pharmaceuticals industry (-4.8%).


Return on Equity

High ROE: MIST has a negative Return on Equity (-189.64%), as it is currently unprofitable.


Return on Assets


Return on Capital Employed


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Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/07/06 12:04
End of Day Share Price 2026/07/02 00:00
Earnings2026/03/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Milestone Pharmaceuticals Inc. is covered by 9 analysts. 6 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Patrick TrucchioH.C. Wainwright & Co.
Brandon FolkesH.C. Wainwright & Co.
Christopher HowertonJefferies LLC