Intra-Cellular Therapies, Inc.

NasdaqGS:ITCI Stock Report

Market Cap: US$14.0b

This company has been acquired

The company may no longer be operating, as it has been acquired. Find out why through their latest events.

Intra-Cellular Therapies Management

Management criteria checks 3/4

Intra-Cellular Therapies' CEO is Sharon Mates, appointed in May 2002, has a tenure of 22.92 years. total yearly compensation is $13.31M, comprised of 7% salary and 93% bonuses, including company stock and options. directly owns 1.07% of the company’s shares, worth $149.76M. The average tenure of the management team and the board of directors is 6.5 years and 11.3 years respectively.

Key information

Sharon Mates

Chief executive officer

US$13.3m

Total compensation

CEO salary percentage7.04%
CEO tenure22.9yrs
CEO ownership1.1%
Management average tenure6.5yrs
Board average tenure11.3yrs

Recent management updates

Recent updates

Seeking Alpha • Mar 05

Johnson & Johnson: No More Tears, Just Gains In Intra-Cellular Acquisition

Summary Intra-Cellular Therapies' Caplyta shows strong sales growth and label expansion potential, making it a valuable acquisition for Johnson & Johnson at $14 billion. JNJ's acquisition of ITCI is strategic, replacing its aging Invega with Caplyta, which has patent protection until 2033 and ongoing clinical trials for new formulations. The $14 billion price tag is justified given Caplyta's advanced clinical stage, FDA approvals, and potential blockbuster status in the schizophrenia and bipolar disorder markets. Schizophrenia and MDD markets are substantial, with Caplyta positioned to capture significant market share, enhancing JNJ's portfolio amidst broader portfolio challenges. Read the full article on Seeking Alpha
Seeking Alpha • Jan 13

What Johnson & Johnson Is Getting With The Acquisition Of Intra-Cellular Therapies

Summary Johnson & Johnson is acquiring Intra-Cellular Therapies for $14.6 billion or $132 per share. Caplyta's peak sales potential exceeds $5 billion in the hands of J&J, driven by growth in schizophrenia, bipolar disorder, and the pending approval in major depressive disorder. The deal also brings Intra-Cellular Therapies' early-stage pipeline that adds to the long-term upside potential of the deal. Intellectual property risk on Caplyta is substantially reduced with last week's settlement with Sandoz, but not entirely eliminated as it does not stop other generic manufacturers from trying. I believe J&J is paying (at least) a fair price, with decent likelihood of creating substantial long-term value for the company. Read the full article on Seeking Alpha
Seeking Alpha • Dec 09

Intra-Cellular Therapies: Parkinson's Disease Drug Expansion Could Be The Next Huge Move

Summary CAPLYTA showed strong revenue growth, with Q3 2024 net product revenues of $125.8 million, which was a 39% year-over-year increase. Potential revenue boost if CAPLYTA's label is expanded to include it as an adjunctive therapy for major depressive disorder, addressing a significant unmet need. Lenrispodun, a PDE inhibitor, is in a phase 2 study for Parkinson's Disease, with potential data release by late 2025/early 2026, offering another blockbuster opportunity. Financially stable with $1 billion in cash and investments, but may raise funds in 2025 to support sales force expansion and R&D programs. Read the full article on Seeking Alpha
Seeking Alpha • Sep 04

Peaking Back In On Intra-Cellular Therapies

Summary Intra-Cellular Therapies has shown significant progress since we last looked at it in November, with its stock rising nearly 30% since then and CAPLYTA prescriptions growing 36% YoY. CAPLYTA is also poised for FDA approval for major depressive disorder, potentially expanding its market significantly, with an sNDA submission expected in the second half of 2024. The company reported strong Q2 results, with revenues up 45% YoY and a reduced net loss, while analysts remain largely positive with multiple Buy ratings. However, despite positive developments, the stock appears fully valued, trading at over 10 times revenues and 100 times FY2025E EPS, with notable insider selling in August. An updated analysis around Intra-Cellular Therapies follows in the paragraphs below. Read the full article on Seeking Alpha
Seeking Alpha • Jun 19

Intra-Cellular Brightens MDD Outlook With Caplyta Success

Summary Caplyta (lumateperone) shows significant promise as an adjunctive treatment for Major Depressive Disorder. Caplyta's unique pharmacological profile targeting serotonin, dopamine, and glutamate pathways sets it apart in the saturated MDD market. Intra-Cellular's financial stability is supported by strong sales growth and sufficient cash reserves to sustain operations until 2027. I recommend buying ITCI stock as a high-risk, high-return component of a barbell investment strategy. Read the full article on Seeking Alpha
Seeking Alpha • Apr 16

Intra-Cellular: More Upside Possible Even After Positive MDD Treatment Data

Summary Intra-Cellular Therapies, Inc. achieved positive results from Study 501, using lumateperone as an adjunctive therapy for the treatment of patients with MDD; Both primary and secondary endpoints achieved with statistical significance. The Major Depressive Disorder market across the eight major markets is expected to reach $9.6 billion by 2029. Results from the second phase 3 study using lumateperone as an adjunctive therapy for MDD, Study 502, are expected to be released in Q2 of 2024. With two positive phase 3 studies achieved, there is the potential for submission of New Drug Application of lumateperone to the FDA for the treatment of patients with MDD in the 2nd half of 2024. Read the full article on Seeking Alpha

CEO Compensation Analysis

How has Sharon Mates's remuneration changed compared to Intra-Cellular Therapies's earnings?
DateTotal CompensationSalaryCompany Earnings
Dec 31 2024US$13mUS$936k

-US$75m

Sep 30 2024n/an/a

-US$86m

Jun 30 2024n/an/a

-US$84m

Mar 31 2024n/an/a

-US$111m

Dec 31 2023US$10mUS$892k

-US$140m

Sep 30 2023n/an/a

-US$155m

Jun 30 2023n/an/a

-US$184m

Mar 31 2023n/an/a

-US$228m

Dec 31 2022US$9mUS$849k

-US$256m

Sep 30 2022n/an/a

-US$298m

Jun 30 2022n/an/a

-US$321m

Mar 31 2022n/an/a

-US$304m

Dec 31 2021US$7mUS$794k

-US$284m

Sep 30 2021n/an/a

-US$259m

Jun 30 2021n/an/a

-US$237m

Mar 31 2021n/an/a

-US$232m

Dec 31 2020US$5mUS$767k

-US$227m

Sep 30 2020n/an/a

-US$207m

Jun 30 2020n/an/a

-US$187m

Mar 31 2020n/an/a

-US$160m

Dec 31 2019US$5mUS$745k

-US$148m

Sep 30 2019n/an/a

-US$148m

Jun 30 2019n/an/a

-US$155m

Mar 31 2019n/an/a

-US$154m

Dec 31 2018US$4mUS$723k

-US$155m

Compensation vs Market: Sharon's total compensation ($USD13.31M) is about average for companies of similar size in the US market ($USD13.52M).

Compensation vs Earnings: Sharon's compensation has increased whilst the company is unprofitable.

CEO

Sharon Mates (71 yo)

22.9yrs
Tenure
US$13,305,510
Compensation

Dr. Sharon Mates, Ph.D. co-founded Intra-Cellular Therapies, Inc. (a/k/a ITI) in May 2002 and was its President until March 19, 2024. She has been Chairman and Chief Executive Officer of Intra-Cellular The...

Leadership Team

NamePositionTenureCompensationOwnership
Sharon Mates
Co-Founder22.9yrsUS$13.31m1.07%
$ 149.8m
Michael Halstead
President1.1yrsUS$4.86m0.020%
$ 2.8m
Sanjeev Narula
Executive VPless than a yearUS$4.17mno data
Suresh Durgam
Executive VP & Chief Medical Officer6.7yrsUS$3.71m0.040%
$ 5.7m
Mark Neumann
EVP & Chief Commercial Officer6.5yrsUS$3.76m0.050%
$ 7.0m
Robert Davis
Senior VP & Chief Scientific Officer9.4yrsUS$2.13mno data
Juan Sanchez
Vice President of Corporate Communications & Investor Relations11.1yrsUS$1.38mno data
Karen Sheehy
Senior VP & Chief Compliance Officer5.8yrsno datano data
John Condon
Senior VPno datano datano data
Michael Olchaskey
Senior VP & Head of Regulatory Affairs6.6yrsno datano data
John Bardi
Senior VP of Market Access6.1yrsno datano data
Willie Earley
Senior VP & Head of Clinical Development3yrsno datano data
6.5yrs
Average Tenure
61yo
Average Age

Experienced Management: ITCI's management team is seasoned and experienced (6.5 years average tenure).

Board Members

NamePositionTenureCompensationOwnership
Sharon Mates
Co-Founder11.7yrsUS$13.31m1.07%
$ 149.8m
Rory Riggs
Independent Director11.3yrsUS$471.86k0.12%
$ 17.3m
Robert Van Nostrand
Lead Independent Director11.3yrsUS$513.38k0.011%
$ 1.5m
Joel Marcus
Independent Director11.7yrsUS$474.97k0.045%
$ 6.4m
Carol Tamminga
Chairman of Medical Advisory Boardno datano datano data
John Kane
Member of Medical Advisory Boardno datano datano data
Jeffrey Lieberman
Member of Medical Advisory Boardno datano datano data
Christoph Correll
Member of Medical Advisory Boardno datano datano data
Donald Goff
Member of Medical Advisory Boardno datano datano data
Eduardo Salas
Independent Director3yrsUS$470.76k0.0015%
$ 206.2k
11.3yrs
Average Tenure
71yo
Average Age

Experienced Board: ITCI's board of directors are seasoned and experienced ( 11.3 years average tenure).

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2025/04/01 20:53
End of Day Share Price 2025/04/01 00:00
Earnings2024/12/31
Annual Earnings2024/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

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Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Intra-Cellular Therapies, Inc. is covered by 7 analysts. 13 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Robert HazlettBTIG
Jason ButlerCitizens JMP Securities, LLC
Corinne JohnsonGoldman Sachs