Inozyme Pharma, Inc.

NasdaqGS:INZY Stock Report

Market Cap: US$259.7m

This company has been acquired

The company may no longer be operating, as it has been acquired. Find out why through their latest events.

Inozyme Pharma Past Earnings Performance

Past criteria checks 0/6

Inozyme Pharma's earnings have been declining at an average annual rate of -18.5%, while the Biotechs industry saw earnings growing at 15.2% annually.

Key information

-18.48%

Earnings growth rate

58.45%

EPS growth rate

Biotechs Industry Growth17.04%
Revenue growth raten/a
Return on equity-335.61%
Net Marginn/a
Last Earnings Update31 Mar 2025

Recent past performance updates

No updates

Recent updates

Analysis Article • Nov 17

Does Inozyme Pharma (NASDAQ:INZY) Have A Healthy Balance Sheet?

Legendary fund manager Li Lu (who Charlie Munger backed) once said, 'The biggest investment risk is not the volatility...
Analysis Article • Aug 03

Does Inozyme Pharma (NASDAQ:INZY) Have A Healthy Balance Sheet?

The external fund manager backed by Berkshire Hathaway's Charlie Munger, Li Lu, makes no bones about it when he says...
Seeking Alpha • Jul 30

Inozyme: Q4 Of 2024 Phase 1 INZ-701 Data Could Lead To Indication Expansion

Summary Inozyme Pharma, Inc. interim data from the phase 1 SEAPORT-1 study, using INZ-701 for the treatment of patients with end-stage kidney disease with hemodialysis with calciphylaxis, expected Q4 of 2024. Fast Track Designation given by the FDA for the use of INZ-701 for the treatment of patients with ABCC6 Deficiency. Meeting with FDA to discuss potential of initiating a pivotal late-stage study using INZ-701 for the treatment of pediatric patients with ABCC6 Deficiency, expected end of 2024. Company had $166.2 million in cash as of March 31st of 2024; Enough cash on hand to fund its operations into Q4 of 2025. Read the full article on Seeking Alpha
Analysis Article • Apr 11

Inozyme Pharma (NASDAQ:INZY) Has Debt But No Earnings; Should You Worry?

The external fund manager backed by Berkshire Hathaway's Charlie Munger, Li Lu, makes no bones about it when he says...
Seeking Alpha • Mar 08

Inozyme: Several Catalysts To Move Rare Disease Pipeline Programs Forward

Summary 48-week results from the phase 1/2 studies, using INZ-701 for the treatment of patients with ENPP1 Deficiency and ABCC6 Deficiency, expected in Q1 2024. Results from the phase 3 ENERGY-3 study, using INZ-701 for the treatment of patients with ENPP1 Deficiency, expected in mid-2025. An expansion opportunity exists for this company, which would be the advancement of INZ-701 for calciphylaxis that occurs in patients with end-stage kidney disease receiving hemodialysis. Initiation of phase 1 SEAPORT-1 study, using INZ-701 for calciphylaxis that occurs in patients with end-stage kidney disease receiving hemodialysis expected in 1st half 2024; Interim data Q4 of 2024. Read the full article on Seeking Alpha
Seeking Alpha • Aug 15

Inozyme Pharma GAAP EPS of -$0.38

Inozyme Pharma press release (NASDAQ:INZY): Q2 GAAP EPS of -$0.38. Cash, cash equivalents, and investments were $151.5M as of June 30, 2022. Based on its current plans, the company expects that its cash, cash equivalents, and investments as of June 30, 2022, together with the $25M available under the first tranche of its debt facility, will enable the company to fund its cash flow requirements into the second quarter of 2024.
Seeking Alpha • Jul 19

Inozyme Pharma releases positive early-stage data on candidate for ABCC6 Deficiency

Data from a handful of patients in the phase 1 portion of a phase 1/2 trial showed that Inozyme Pharma's (NASDAQ:INZY) INZ-701 led to positive biomarker, safety, and pharmacokinetic results in adults with ABCC6 Deficiency. All three adults showed rapid and significant increases in levels of pyrophosphate (PPi), a calcification inhibitor, after receiving the drug at a dose of 0.2 mg/kg. The company said in preclinical studies, PPi was predictive biomarker of therapeutic benefit. There were no serious adverse events reported. A grade 1 event was reported, though it was not related to INZ-701. Following review by a data safety monitoring board, InoZyme (INZY) plans to begin dosing in the next 0.6 mg/kg cohort this quarter and report topline data from Phase 1/2  trial in Q1 2023. Read about Inozyme's (INZY) recent partnership with the Rady Children’s Institute for Genomic Medicine.
Analysis Article • Jul 12

Will Inozyme Pharma (NASDAQ:INZY) Spend Its Cash Wisely?

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, biotech and mining...
Analysis Article • Apr 06

We're Keeping An Eye On Inozyme Pharma's (NASDAQ:INZY) Cash Burn Rate

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, biotech and mining...
Analysis Article • Dec 22

Here's Why We're Not Too Worried About Inozyme Pharma's (NASDAQ:INZY) Cash Burn Situation

Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...
Analysis Article • Sep 08

Companies Like Inozyme Pharma (NASDAQ:INZY) Are In A Position To Invest In Growth

Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...
Analysis Article • May 22

We're Not Very Worried About Inozyme Pharma's (NASDAQ:INZY) Cash Burn Rate

Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...
Analysis Article • Feb 06

We're Hopeful That Inozyme Pharma (NASDAQ:INZY) Will Use Its Cash Wisely

Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...

Revenue & Expenses Breakdown

How Inozyme Pharma makes and spends money. Based on latest reported earnings, on an LTM basis.

Earnings and Revenue History

NasdaqGS:INZY Revenue, expenses and earnings (USD Millions)
DateRevenueEarningsG+A ExpensesR&D Expenses
31 Mar 250-1072184
31 Dec 240-1022183
30 Sep 240-962178
30 Jun 240-892172
31 Mar 240-772162
31 Dec 230-712155
30 Sep 230-682251
30 Jun 230-682250
31 Mar 230-682148
31 Dec 220-672148
30 Sep 220-672147
30 Jun 220-652144
31 Mar 220-622042
31 Dec 210-572037
30 Sep 210-491931
30 Jun 210-631746
31 Mar 210-601446
31 Dec 200-561146
30 Sep 200-52844
30 Jun 200-28623
31 Mar 200-22518
31 Dec 190-20516

Quality Earnings: INZY is currently unprofitable.

Growing Profit Margin: INZY is currently unprofitable.

Free Cash Flow vs Earnings Analysis

Past Earnings Growth Analysis

Earnings Trend: INZY is unprofitable, and losses have increased over the past 5 years at a rate of 18.5% per year.

Accelerating Growth: Unable to compare INZY's earnings growth over the past year to its 5-year average as it is currently unprofitable

Earnings vs Industry: INZY is unprofitable, making it difficult to compare its past year earnings growth to the Biotechs industry (21.7%).

Return on Equity

High ROE: INZY has a negative Return on Equity (-335.61%), as it is currently unprofitable.

Return on Assets

Return on Capital Employed

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Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2025/07/03 17:58
End of Day Share Price 2025/06/30 00:00
Earnings2025/03/31
Annual Earnings2024/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Inozyme Pharma, Inc. is covered by 4 analysts. 1 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Edward WhiteH.C. Wainwright & Co.
Joseph StringerNeedham & Company
Dae Gon HaStifel, Equities Research