Humacyte, Inc.

NasdaqGS:HUMA Stock Report

Market Cap: US$206.5m

Humacyte Management

Management criteria checks 1/4

Humacyte's CEO is Laura Niklason, appointed in Jan 2004, has a tenure of 22.33 years. total yearly compensation is $5.23M, comprised of 12.1% salary and 87.9% bonuses, including company stock and options. directly owns 0.11% of the company’s shares, worth $226.80K. The average tenure of the management team and the board of directors is 1.3 years and 4.8 years respectively.

Key information

Laura Niklason

Chief executive officer

US$5.2m

Total compensation

CEO salary percentage12.10%
CEO tenure22.3yrs
CEO ownership0.1%
Management average tenure1.3yrs
Board average tenure4.8yrs

Recent management updates

Recent updates

Seeking Alpha • Feb 09

Humacyte: Positive News For Symvess At Last, But Long-Term Threats Persist

Summary Humacyte, Inc. remains rated Hold despite a DoD funding catalyst revealed today, as commercial traction for Symvess is not yet proven. Symvess is the only FDA-approved human-derived bioengineered blood vessel, but Q3 revenue was just $700k, and uptake remains limited. HUMA's funding runway is constrained, with recent capital raises offset by high R&D spending; further dilution or cost cuts may be needed. Key 2026 catalysts are dialysis data readouts and BLA submissions, not the recent DoD news, given ongoing risks and modest near-term sales. Read the full article on Seeking Alpha
Analysis Article • Sep 19

Here's Why Humacyte (NASDAQ:HUMA) Can Afford Some Debt

Howard Marks put it nicely when he said that, rather than worrying about share price volatility, 'The possibility of...
Analysis Article • May 21

Is Humacyte (NASDAQ:HUMA) A Risky Investment?

The external fund manager backed by Berkshire Hathaway's Charlie Munger, Li Lu, makes no bones about it when he says...
Seeking Alpha • Mar 24

Humacyte: Symvess' Approval And Launch Are Just The First Steps To Adoption (Downgrade)

Summary Humacyte's stock has dropped 29% since December, despite FDA approval of Symvess. Symvess faces slow adoption due to the need for long-term outcomes data. Humacyte's financial health is precarious, with high operating expenses and a cash runway extending only into late 2025, raising concerns about future dilution. Given these challenges, I downgrade HUMA to "Sell," as achieving a return on investment for Symvess seems unlikely without significant financial strain. Read the full article on Seeking Alpha
Seeking Alpha • Jan 08

Humacyte: Expect A Slow Launch, But Vascular Trauma Indication Is Just A Beginning

Summary Humacyte, Inc. arrived on the Nasdaq in 2021 via a SPAC deal and reappeared on my radar after the Symvess approval in vascular trauma repair. Platform enabling off-the-shelf bioengineered tissues could transform the field of regenerative medicine. There's a large addressable market across 3 lead indications alone (trauma, dialysis & PAD) + significant optionality for more complex projects (i.e., biovascular pancreas in diabetes). Key concerns include slow launch out of the gate, continued cash burn & dilution, competition, and manufacturing capacity. My Action Plan: I remain on the sidelines for HUMA stock and will continue to monitor launch metrics as well as pipeline progress. Read the full article on Seeking Alpha
Seeking Alpha • Dec 23

Humacyte's Symvess Debut: A Milestone With Lingering Concerns (Rating Downgrade)

Summary Humacyte stock has dropped 46% since July, mainly due to FDA review delays and mixed Phase 3 trial results for their ATEVs in hemodialysis. Despite FDA approval of Symvess for vascular trauma, its market potential is limited, and adoption is expected to be slow and costly. Phase 3 trial data for ATEVs in hemodialysis patients showed higher thrombosis and infection rates, raising concerns about its safety and efficacy. Humacyte's financial situation remains precarious, with high operating expenses and potential ongoing dilution, leading to a downgrade on HUMA stock from "buy" to "hold". Read the full article on Seeking Alpha
Seeking Alpha • Dec 14

Humacyte: FDA Waiting Game Bleeding Company Dry

Summary Humacyte's innovative ATEV technology shows promise but faces delays in FDA approval, initially expected in Aug, causing financial strain and uncertainty about its market potential. Despite strong clinical data, the FDA's postponement of the ATEV approval has left Humacyte in a precarious financial position, forcing it to raise ~$45m since August. The lack of a clear FDA timeline creates significant risk for investors, leading to a downgrade from "buy" to "hold" due to potential further delays. The market opportunity for ATEVs remains uncertain, questioning whether Humacyte stock can achieve significant upside even if FDA approval is granted. Read the full article on Seeking Alpha
Seeking Alpha • Sep 24

Humacyte: Navigating The FDA Uncertainty And ATEV's Potential

Summary Humacyte’s acellular tissue engineered vessel (ATEV) shows promise in trauma and dialysis, with positive clinical trial results and potential FDA approval by year-end. Despite FDA delays, Humacyte remains optimistic but faces financial instability, with only $43.6 million in cash, supporting operations for 1.5 quarters. HUMA stock is rated as a moderate "Buy" for high-risk tolerant investors, given the potential for FDA approval and significant market capture in trauma. Risks include potential FDA rejection, financial distress, and management's recent share sales, which warrant cautious investment consideration. Read the full article on Seeking Alpha
Analysis Article • Aug 16

Will Humacyte (NASDAQ:HUMA) Spend Its Cash Wisely?

We can readily understand why investors are attracted to unprofitable companies. For example, although Amazon.com made...
Seeking Alpha • Jul 17

Humacyte: Pioneering Vascular Solutions With High-Stakes Potential

Summary Humacyte is developing HAVs for multiple indications, showing promising clinical outcomes, and receiving FDA RMAT designation for faster approval processes. The market for vascular repairs is large and growing, with Humacyte's HAVs positioned as a potentially superior option to traditional treatments. Financially, Humacyte holds sufficient short-term assets but faces significant long-term liabilities and a potential cash crunch within a year. I recommend buying HUMA as a speculative, high-risk/high-reward addition to a diversified investment portfolio. Read the full article on Seeking Alpha
Analysis Article • Jun 05

Shareholders Will Probably Not Have Any Issues With Humacyte, Inc.'s (NASDAQ:HUMA) CEO Compensation

Key Insights Humacyte's Annual General Meeting to take place on 11th of June Total pay for CEO Laura Niklason includes...
Seeking Alpha • May 14

Humacyte: A Strong Opportunity In Wound Healing - A 'Buy' Before Price Gets Too High

Summary Humacyte's stock price has recently been on an impressive bull run, jumping from $4.50 to $6.50 after management announced Q1 2024 earnings. The company's market cap valuation is currently around $765 million - I believe this could rise >$1bn if the company secures a first commercial approval this year, as is likely. Humacyte focuses on regenerative medicine technology, specifically bioengineered human tissues, and has a Biologics License Application accepted by the FDA for its Human Acellular Vessels. The opportunity is in vascular wound treatment, and the FDA has set a decision date for Aug. 10, after awarding a priority review. Humacyte's innovative product that uses a degradable polymer mesh to encourage cell proliferation may be an improvement on current standards of care. Read the full article on Seeking Alpha

CEO Compensation Analysis

How has Laura Niklason's remuneration changed compared to Humacyte's earnings?
DateTotal CompensationSalaryCompany Earnings
Mar 31 2026n/an/a

-US$95m

Dec 31 2025US$5mUS$634k

-US$41m

Sep 30 2025n/an/a

-US$39m

Jun 30 2025n/an/a

-US$61m

Mar 31 2025n/an/a

-US$80m

Dec 31 2024US$905kUS$612k

-US$149m

Sep 30 2024n/an/a

-US$153m

Jun 30 2024n/an/a

-US$140m

Mar 31 2024n/an/a

-US$106m

Dec 31 2023US$3mUS$604k

-US$111m

Sep 30 2023n/an/a

-US$89m

Jun 30 2023n/an/a

-US$89m

Mar 31 2023n/an/a

-US$29m

Dec 31 2022US$2mUS$500k

-US$12m

Sep 30 2022n/an/a

US$34m

Jun 30 2022n/an/a

US$28m

Mar 31 2022n/an/a

-US$26m

Dec 31 2021US$11mUS$500k

-US$26m

Sep 30 2021n/an/a

-US$85m

Jun 30 2021n/an/a

-US$71m

Mar 31 2021n/an/a

-US$69m

Dec 31 2020US$619kUS$75k

-US$67m

Compensation vs Market: Laura's total compensation ($USD5.23M) is above average for companies of similar size in the US market ($USD1.71M).

Compensation vs Earnings: Laura's compensation has increased whilst the company is unprofitable.

CEO

Laura Niklason (62 yo)

22.3yrs
Tenure
US$5,234,908
Compensation

Dr. Laura E. Niklason, M.D., Ph D., serves as President and Chief Executive Officer at Humacyte, Inc. since November 2020. She founded Humacyte, Inc. in 2004 and served as its Chief Scientist from 2005 to...

Leadership Team

NamePositionTenureCompensationOwnership
Laura Niklason
Founder22.3yrsUS$5.23m0.11%
$ 226.8k
Dale Sander
CFO, Chief Corporate Development Officer & Treasurer5.5yrsUS$2.13m0.019%
$ 39.6k
Shamik Parikh
Chief Medical Officer4.1yrsUS$2.10m0.0034%
$ 7.0k
Sabrina Osborne
Chief People Officerno datano datano data
Lisa Molyneux
Executive Vice President of Enterprise Planning & Analysis1.3yrsno datano data
Heather Connelly
Executive Vice President Regulatory Affairs & Quality1.3yrsno datano data
Rick McElheny
Senior Vice President of Business Developmentless than a yearno datano data
Jim Mercadante
Chief Commercial Officerless than a yearno datano data
Todd Rasmussen
Chief Surgical Officerno datano datano data
1.3yrs
Average Tenure
62yo
Average Age

Experienced Management: HUMA's management team is not considered experienced ( 1.3 years average tenure), which suggests a new team.

Board Members

NamePositionTenureCompensationOwnership
Laura Niklason
Founder22.3yrsUS$5.23m0.11%
$ 226.8k
Max Wallace
Independent Director20.9yrsUS$207.80k0.029%
$ 60.1k
Brady Dougan
Director21.3yrsUS$202.80k0%
$ 0
Susan Windham-Bannister
Independent Director4.8yrsUS$207.80k0%
$ 0
Todd Pope
Independent Directorno dataUS$207.80k0%
$ 0
Kathleen Sebelius
Independent Chairman of the Board10.7yrsUS$227.80k0.041%
$ 84.8k
Michael Constantino
Independent Director4.8yrsUS$210.30k0.015%
$ 30.6k
Diane Seimetz
Independent Director3.9yrsUS$202.80k0%
$ 0
Emery Brown
Independent Director4.8yrsUS$202.80k0%
$ 0
Charles Green
Independent Director3.7yrsUS$202.80k0.0038%
$ 7.8k
John Bamforth
Independent Director1.9yrsUS$202.80k0%
$ 0
Keith Jones
Independent Director1.9yrsUS$202.80k0%
$ 0
4.8yrs
Average Tenure
65.5yo
Average Age

Experienced Board: HUMA's board of directors are considered experienced (4.8 years average tenure).

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/05/17 13:55
End of Day Share Price 2026/05/15 00:00
Earnings2026/03/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

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Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Humacyte, Inc. is covered by 9 analysts. 5 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Matthew MiksicBarclays
Bruce JacksonBenchmark Company
Michael GormanBTIG