Stock Analysis

Does Gilead’s Raised Guidance and Earnings Surge Reinforce the Bull Case for GILD?

  • Gilead Sciences recently reported strong third-quarter earnings with revenue of US$7.77 billion and net income of US$3.05 billion, raised its 2025 earnings guidance, continued share buybacks, and affirmed its quarterly dividend.
  • An important insight is that the company achieved a very large increase in year-over-year net income and further tightened its product sales and EPS range upward for 2025, reflecting management confidence and ongoing operational momentum.
  • We'll look at how Gilead's raised full-year guidance and robust earnings momentum may shift its long-term investment narrative and outlook.

Trump has pledged to "unleash" American oil and gas and these 22 US stocks have developments that are poised to benefit.

Advertisement

Gilead Sciences Investment Narrative Recap

To be a shareholder in Gilead Sciences, you need to believe the company's strong portfolio in HIV, oncology, and liver disease, combined with a robust pipeline and prudent capital allocation, can offset regulatory, pricing, and generic competition risks. The recent earnings beat and raised guidance support the short-term catalyst of accelerating EPS growth, but do not materially shift the key risk: Gilead’s long-term vulnerability to pricing pressure and reliance on HIV revenues.

Among recent announcements, Gilead’s revised 2025 guidance, lifting product sales and EPS expectations, is the most relevant here. This move reinforces management’s current confidence in operational momentum, underpinned by strong net income growth and persistent share buybacks, which directly feed into key catalysts around earnings growth and shareholder returns.

Yet, in contrast, investors should be aware of ongoing risks related to policy-driven pricing pressure on Gilead’s core HIV franchise that could ...

Read the full narrative on Gilead Sciences (it's free!)

Gilead Sciences' outlook anticipates $32.3 billion in revenue and $10.0 billion in earnings by 2028. This is based on an annual revenue growth rate of 3.8% and reflects an increase in earnings of $3.7 billion from the current $6.3 billion level.

Uncover how Gilead Sciences' forecasts yield a $127.23 fair value, a 4% upside to its current price.

Exploring Other Perspectives

GILD Community Fair Values as at Nov 2025
GILD Community Fair Values as at Nov 2025

The highest analyst estimates give a much more optimistic outlook, forecasting US$33.9 billion in revenue and US$10.8 billion in earnings by 2028, centered on rapid new drug adoption. If you’re considering Gilead, remember that these optimistic views depend on stronger product launches and less pricing erosion than the consensus expects. Think about how recent news might alter either view and why opinions across the market can vary so much, even when all analysts see the same headlines.

Explore 11 other fair value estimates on Gilead Sciences - why the stock might be worth 23% less than the current price!

Build Your Own Gilead Sciences Narrative

Disagree with existing narratives? Create your own in under 3 minutes - extraordinary investment returns rarely come from following the herd.

Ready To Venture Into Other Investment Styles?

Markets shift fast. These stocks won't stay hidden for long. Get the list while it matters:

This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.

New: Manage All Your Stock Portfolios in One Place

We've created the ultimate portfolio companion for stock investors, and it's free.

• Connect an unlimited number of Portfolios and see your total in one currency
• Be alerted to new Warning Signs or Risks via email or mobile
• Track the Fair Value of your stocks

Try a Demo Portfolio for Free

Have feedback on this article? Concerned about the content? Get in touch with us directly. Alternatively, email editorial-team@simplywallst.com