AVROBIO Management

Management criteria checks 3/4

AVROBIO's CEO is Erik Ostrowski, appointed in Jan 2019, has a tenure of 5.25 years. total yearly compensation is $1.59M, comprised of 31.7% salary and 68.3% bonuses, including company stock and options. directly owns 0.065% of the company’s shares, worth $35.14K. The average tenure of the management team and the board of directors is 2.5 years and 6 years respectively.

Key information

Erik Ostrowski

Chief executive officer

US$1.6m

Total compensation

CEO salary percentage	31.7%
CEO tenure	5.3yrs
CEO ownership	0.07%
Management average tenure	2.5yrs
Board average tenure	6yrs

Recent management updates

Recent updates

Avrobio rises as gene therapy for Gaucher disease gets ILAP designation in UK

Oct 18

Avrobio stock rises as kidney disease gene therapy gets FDA rare pediatric disease status

Sep 20

Here's Why We're Not Too Worried About AVROBIO's (NASDAQ:AVRO) Cash Burn Situation

Mar 08

AVROBIO: Undercovered Gene Therapy Developer With Excellent Promise

Dec 25

We Think AVROBIO (NASDAQ:AVRO) Can Afford To Drive Business Growth

Nov 23

AVROBIO readies $75M equity offering

Nov 19

AVROBIO EPS misses by $0.19

Nov 05

CEO Compensation Analysis

How has Erik Ostrowski's remuneration changed compared to AVROBIO's earnings?
Date	Total Compensation	Salary	Company Earnings
Dec 31 2023	US$2m	US$504k	US$12m
Sep 30 2023	n/a	n/a	-US$4m
Jun 30 2023	n/a	n/a	-US$5m
Mar 31 2023	n/a	n/a	-US$101m
Dec 31 2022	US$1m	US$460k	-US$106m
Sep 30 2022	n/a	n/a	-US$109m
Jun 30 2022	n/a	n/a	-US$119m
Mar 31 2022	n/a	n/a	-US$122m
Dec 31 2021	US$3m	US$439k	-US$119m
Sep 30 2021	n/a	n/a	-US$119m
Jun 30 2021	n/a	n/a	-US$123m
Mar 31 2021	n/a	n/a	-US$121m
Dec 31 2020	US$2m	US$424k	-US$120m
Sep 30 2020	n/a	n/a	-US$114m
Jun 30 2020	n/a	n/a	-US$95m
Mar 31 2020	n/a	n/a	-US$82m
Dec 31 2019	US$3m	US$412k	-US$73m

Compensation vs Market: Erik's total compensation ($USD1.59M) is above average for companies of similar size in the US market ($USD677.87K).

Compensation vs Earnings: Erik's compensation has been consistent with company performance over the past year.

CEO

Erik Ostrowski (51 yo)

5.3yrs

Tenure

US$1,590,892

Compensation

Mr. Erik John Ostrowski, MBA, has been Chief Financial Officer and Treasurer at AVROBIO, Inc since January 2019 and served as its Principal Accounting Officer. He serves as President and Interim Chief Exec...

Leadership Team

Name	Position	Tenure	Compensation	Ownership
Erik Ostrowski	President	5.3yrs	US$1.59m	0.065% $ 35.1k
Azadeh Golipour	Chief Technology Officer	2.3yrs	US$1.27m	0.084% $ 45.2k
Essra Ridha	Chief Medical Officer	2.5yrs	US$1.34m	0.035% $ 19.1k
Jeffrey Medin	Scientific Founder	no data	no data	no data
Steven Avruch	Chief Legal Officer & Secretary	5.3yrs	US$1.77m	0.049% $ 26.4k
Scott Gottesman	Vice President of Human Resource	2.3yrs	no data	no data
Kirsten Dupuis	Chief of Staff	no data	no data	no data

2.5yrs

Average Tenure

47yo

Average Age

Experienced Management: AVRO's management team is considered experienced (2.5 years average tenure).

Board Members

Name	Position	Tenure	Compensation	Ownership
Ian T. Clark	Independent Director	6.3yrs	US$63.97k	0% $ 0
Phillip Donenberg	Independent Non-Employee Director	5.8yrs	US$72.97k	0.0045% $ 2.4k
Bruce Booth	Independent Chairman of the Board	8.2yrs	US$98.97k	0% $ 0
Philip Vickers	Independent Director	5.3yrs	US$73.97k	0.011% $ 5.8k
Gail Farfel	Director	3.5yrs	US$61.47k	0% $ 0
Annalisa Lisa Jenkins	Independent Director	6yrs	US$76.97k	0% $ 0
Christopher Paige	Independent Director	8.3yrs	US$72.97k	0.56% $ 303.0k

6.0yrs

Average Tenure

62yo

Average Age

Experienced Board: AVRO's board of directors are considered experienced (6 years average tenure).

AVROBIO Management

Management criteria checks 3/4

Key information

Recent management updates

Chief Business Officer notifies of intention to sell stock

Co- Founder exercised options to buy US$104k worth of stock.

Insufficient new directors

Insufficient new directors

Insufficient new directors

Insufficient new directors

Recent updates

New major risk - Revenue and earnings growth

New minor risk - Shareholder dilution

AVROBIO, Inc. (NasdaqGS:AVRO) entered into an agreement to acquire Tectonic Therapeutic, Inc.

AVROBIO, Inc. (NasdaqGS:AVRO) entered into an agreement to acquire Tectonic Therapeutic, Inc.

No longer forecast to breakeven

Price target decreased by 16% to US$3.00

New major risk - Revenue and earnings growth

Chief Business Officer notifies of intention to sell stock

Novartis Pharma AG and Novartis Pharmaceuticals Corporation entered into an Asset Purchase Agreement to acquire Cystinosis Gene Therapy Program from AVROBIO, Inc. (NasdaqGS:AVRO) for $87.5 million.

Price target decreased by 8.5% to US$3.58

Novartis Pharma AG and Novartis Pharmaceuticals Corporation entered into an Asset Purchase Agreement to acquire Cystinosis Gene Therapy Program from AVROBIO, Inc. (NasdaqGS:AVRO) for $87.5 million.

Co- Founder exercised options to buy US$104k worth of stock.

AVROBIO, Inc. Announces New Positive Clinical Data and Outlines Clinical Development Plan Following Regulatory Discussions for Its Gaucher Disease Gene Therapy

Price target decreased to US$4.14

Insufficient new directors

Avrobio Receives Rare Pediatric Disease Designation from the U.S. FDA for First-In-Class Gene Therapy for Gaucher Disease

AVROBIO, Inc. Announces Completion of Patient Dosing in First Gene Therapy Clinical Trial for Cystinosis

AVROBIO, Inc. announces U.K. Medicines and Healthcare products Regulatory Agency grant an Innovation Passport under the Innovative Licensing and Access Pathway

Avrobio rises as gene therapy for Gaucher disease gets ILAP designation in UK

AVROBIO, Inc. Reports Favorable Data on Use of Combined State-Of-The-Art in Vitro Cell-Based Assays to Identify Potential Genotoxicity Risk of Integrating Vectors During Preclinical Development

AVROBIO Receives Written Notice from The Nasdaq Stock Market Regarding Minimum Bid Price Requirement

AVROBIO, Inc. Receives Rare Pediatric Disease Designation from U.S. Food and Drug Administration for First Gene Therapy in Development for Cystinosis

Avrobio stock rises as kidney disease gene therapy gets FDA rare pediatric disease status

AVROBIO Inc. Announces Neuronopathic Mucopolysaccharidosis Type II or Hunter Syndrome Clinical Trial Application Accepted by U.K. Regulatory Agency to Initiate Pediatric Phase 1/2 Gene Therapy Trial

AVROBIO granted FDA’s orphan drug designation for metabolic disorder therapy

AVROBIO, Inc.(NasdaqGS:AVRO) dropped from Russell 2500 Index

AVROBIO, Inc. Announces Preclinical Data Demonstrating the Efficacy and Safety of AVR-RD-03 Gene Therapy in A Mouse Model of Infantile Onset Pompe Disease

Avrobio Reports Positive Data from Phase 1/2 Clinical Trial of Investigational Gene Therapy for Cystinosis, Including New Interim Data on Neurocognitive Measures

Price target decreased to US$6.29

Insufficient new directors

AVROBIO, Inc. Reports Interim Data from Phase 1/2 Clinical Trial of Investigational Gene Therapy for Cystinosis

Insufficient new directors

Insufficient new directors

AVROBIO, Inc. Announces the Appointment of Sean O’Bryan as Chief Regulatory Officer

AVROBIO, Inc. Announces New Data from Phase 2 Fab-Gt Clinical Trial Show Variable Engraftment

AVROBIO, Inc Presents Clinician Experience with FAB-GT Clinical Trial and Updated Safety Data for Investigational Gene Therapies in Fabry Disease and Gaucher Disease Type 1

Price target decreased to US$22.88

Price target increased to US$25.14

Here's Why We're Watching AVROBIO's (NASDAQ:AVRO) Cash Burn Situation

We're Keeping An Eye On AVROBIO's (NASDAQ:AVRO) Cash Burn Rate

AVROBIO, Inc.(NasdaqGS:AVRO) dropped from Russell 2500 Growth Index

AVROBIO: Fabrazyme's Full Approval Changes Things

AVROBIO, Inc. Provides Regulatory Update on Investigational AVR-RD-01 for Fabry Disease

AVROBIO, Inc. Announces Two Oral Presentations and Two Posters Featuring Data from Its Pipeline of Lysosomal Disorder Gene Therapy

Here's Why We're Not Too Worried About AVROBIO's (NASDAQ:AVRO) Cash Burn Situation

Price target lowered to US$34.50

AVROBIO, Inc. Receives Orphan Drug Designation from the European Commission for AVR-RD-04, an Investigational Gene Therapy for Cystinosis

AVROBIO, Inc. Announces 100% Kidney Substrate Reduction at 12 Months Post-Gene Therapy in First Patient Dosed with plato Gene Therapy Platform in Fabry Disease Phase 2 Trial

New 90-day high: US$17.11

Avrobio Appoints Diana M. Escolar as Chief Medical Officer

AVROBIO, Inc. Appoints Diana M. Escolar as Chief Medical Officer

AVROBIO: Undercovered Gene Therapy Developer With Excellent Promise

We Think AVROBIO (NASDAQ:AVRO) Can Afford To Drive Business Growth

AVROBIO readies $75M equity offering

AVROBIO, Inc. Avrobio Announces New Positive Clinical Data and Preclinical Data, as Well as Expanded Leading Lysosomal Disorder Gene Therapy Pipeline

AVROBIO EPS misses by $0.19

Price target raised to US$38.50

Avrobio, Inc. Enters into Agreement with University of Manchester, England

Avrobio, Inc. Receives Orphan Drug Designation from the European Medicines Agency for Avr-Rd-02, an Investigational Gene Therapy for Gaucher Disease

New 90-day low: US$15.00

New 90-day low - US$15.85

CEO Compensation Analysis

CEO

Tenure

Compensation

Leadership Team

Average Tenure

Average Age

Board Members