Acumen Pharmaceuticals, Inc.

NasdaqGS:ABOS Stock Report

Market Cap: US$197.9m

Acumen Pharmaceuticals Past Earnings Performance

Past criteria checks 0/6

Acumen Pharmaceuticals's earnings have been declining at an average annual rate of -16.6%, while the Biotechs industry saw earnings growing at 36.2% annually. Revenues have been declining at an average rate of 101.9% per year.

Key information

-16.55%

Earnings growth rate

90.24%

EPS growth rate

Biotechs Industry Growth17.04%
Revenue growth rate-101.87%
Return on equity-129.49%
Net Marginn/a
Last Earnings Update31 Mar 2026

Recent past performance updates

Recent updates

New Narrative Jun 01

Oligomer Antibody And EBD Platform Will Reshape Early Alzheimer’s Treatment Over Time

Catalysts About Acumen Pharmaceuticals Acumen Pharmaceuticals is a clinical stage biotechnology company developing a beta oligomer targeted antibody therapies for Alzheimer's disease. What are the underlying business or industry changes driving this perspective?
New Narrative May 17

Oligomer Antibody And Brain Delivery Advances Will Reshape Early Alzheimer Treatment Prospects

Catalysts About Acumen Pharmaceuticals Acumen Pharmaceuticals is a clinical stage biopharmaceutical company focused on developing a beta oligomer targeted antibody therapies for Alzheimer’s disease. What are the underlying business or industry changes driving this perspective?
Analysis Article Aug 05

Does Acumen Pharmaceuticals (NASDAQ:ABOS) Have A Healthy Balance Sheet?

Some say volatility, rather than debt, is the best way to think about risk as an investor, but Warren Buffett famously...
Seeking Alpha Jul 30

Acumen Pharmaceuticals: Healthy Cash Runway And Market Potential In Alzheimer's

Summary Acumen Pharmaceuticals develops treatments for Alzheimer's disease targeting toxic AβOs, with promising results for sabirnetug in phase 1 clinical trial Intercept-AD. The potential for early AD is approximately 7 million patients, positioning ABOS for significant market share if successful. Sabirnetug’s Phase 1 trial showed promising results, reducing brain amyloid plaques and supporting its mechanism of action for treating early Alzheimer's disease. Acumen Pharmaceuticals has a healthy cash runway, estimated at 3.5 years, and appears undervalued relative to its peers in the biotech sector. Despite the promising data, investing in ABOS is speculative due to the early stages of research and the potential long timeline to FDA approval. Read the full article on Seeking Alpha
Analysis Article Apr 21

Is Acumen Pharmaceuticals (NASDAQ:ABOS) Weighed On By Its Debt Load?

Howard Marks put it nicely when he said that, rather than worrying about share price volatility, 'The possibility of...
Analysis Article Sep 21

Companies Like Acumen Pharmaceuticals (NASDAQ:ABOS) Are In A Position To Invest In Growth

We can readily understand why investors are attracted to unprofitable companies. For example, although...
Analysis Article Feb 01

We're Not Very Worried About Acumen Pharmaceuticals' (NASDAQ:ABOS) Cash Burn Rate

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, biotech and mining...
Analysis Article Oct 16

Acumen Pharmaceuticals (NASDAQ:ABOS) Is In A Good Position To Deliver On Growth Plans

Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...
Seeking Alpha Sep 28

Acumen Pharma at 11-month high on rivals’ Alzheimer’s data

The shares of microcap biotech Acumen Pharmaceuticals, Inc. (NASDAQ:ABOS) more than doubled in value on Wednesday after its rivals Biogen (BIIB) and Eisai (OTCPK:ESALF) (OTCPK:ESALY) announced promising late-stage data for experimental Alzheimer's therapy, lecanemab. In the trial involving nearly 1,800 patients, the amyloid targeting monoclonal antibody cut the cognitive and functional decline in the early stage of Alzheimer's by 27%, compared to placebo, the companies announced late Tuesday. With data validating the amyloid hypothesis in Alzheimer's, developers with similar drugs in their pipeline surged in value. Acumen (ABOS) is advancing its only drug candidate, ACU193 for Alzheimer's, with topline data from a Phase 1 trial expected in H1 2023. ACU193 is a humanized monoclonal antibody that selectively targets amyloid-beta oligomers, which, according to the company, are the most toxic and pathogenic form of amyloid-beta.
Seeking Alpha Jun 30

Acumen Pharmaceuticals initiated at buy at H.C. Wainwright on Alzheimer's candidate

H.C. Wainwright has initiated Acumen Pharmaceuticals (NASDAQ:ABOS) with a buy rating saying the biopharma's early-stage Alzheimer's candidate, ACU193, has promise. The firm has a $15 price target (~207% return based on Wednesday's closing price). Unlike many other Alzheimer's therapies in development -- and marketed ones such as Biogen's (BIIB) Aduhelm (aducanumab) -- that target the removal of beta amyloid plaque from the brain, ACU193 works differently as a anti-amyloid-beta oligomer (AβO) monoclonal antibody. Analyst Andrew Fein noted that ACU193 "lacks the inflammatory effector functions of other [immunoglobulin] subclasses, thereby making it less prone to [amyloid-related imaging abnormalities], a major safety issue with current anti-[amyloid beta] therapies. Acumen (ABOS) said ACU193 prevents toxic AβOs from binding to dendritic spines and preserves neural function. The company added the candidate has the potential for disease slowing as well as cognitive improvement. The ongoing phase 1 trial is expected to enroll 62 subjects with mild cognitive impairment or mild dementia.
Analysis Article May 10

We Think Acumen Pharmaceuticals (NASDAQ:ABOS) Can Afford To Drive Business Growth

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, biotech and mining...
Analysis Article Jan 07

We're Not Very Worried About Acumen Pharmaceuticals' (NASDAQ:ABOS) Cash Burn Rate

Just because a business does not make any money, does not mean that the stock will go down. For example, although...
Analysis Article Oct 01

Acumen Pharmaceuticals (NASDAQ:ABOS) Is In A Good Position To Deliver On Growth Plans

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although...

Revenue & Expenses Breakdown

How Acumen Pharmaceuticals makes and spends money. Based on latest reported earnings, on an LTM basis.


Earnings and Revenue History

NasdaqGS:ABOS Revenue, expenses and earnings (USD Millions)
DateRevenueEarningsG+A ExpensesR&D Expenses
31 Mar 260-11319-9
31 Dec 250-121190
30 Sep 250-1331924
30 Jun 250-1372024
31 Mar 250-1162024
31 Dec 240-102200
30 Sep 240-82200
30 Jun 240-65200
31 Mar 240-56200
31 Dec 230-52190
30 Sep 230-49170
30 Jun 230-46150
31 Mar 230-45140
31 Dec 220-43130
30 Sep 220-38120
30 Jun 220-32110
31 Mar 220-8390
31 Dec 210-10170
30 Sep 210-9350
30 Jun 211-9230
31 Mar 211-3220
31 Dec 201-710
31 Dec 192-810

Quality Earnings: ABOS is currently unprofitable.

Growing Profit Margin: ABOS is currently unprofitable.


Free Cash Flow vs Earnings Analysis


Past Earnings Growth Analysis

Earnings Trend: ABOS is unprofitable, and losses have increased over the past 5 years at a rate of 16.6% per year.

Accelerating Growth: Unable to compare ABOS's earnings growth over the past year to its 5-year average as it is currently unprofitable

Earnings vs Industry: ABOS is unprofitable, making it difficult to compare its past year earnings growth to the Biotechs industry (54.5%).


Return on Equity

High ROE: ABOS has a negative Return on Equity (-129.49%), as it is currently unprofitable.


Return on Assets


Return on Capital Employed


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Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/07/06 00:53
End of Day Share Price 2026/07/06 00:00
Earnings2026/03/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Acumen Pharmaceuticals, Inc. is covered by 7 analysts. 5 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Jason ZemanskyBofA Global Research
Thomas ShraderBTIG
Pete StavropoulosCantor Fitzgerald & Co.