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Agios Pharmaceuticals, Inc.LSE:0HB0 Stock Report

Market Cap US$1.7b
Share Price
US$28.09
n/a
1Y-13.4%
7D0.9%
Portfolio Value
View

Agios Pharmaceuticals, Inc.

LSE:0HB0 Stock Report

Market Cap: US$1.7b

Agios Pharmaceuticals (0HB0) Stock Overview

A biopharmaceutical company, discovers and develops medicines in the field of cellular metabolism in the United States. More details

0HB0 fundamental analysis
Snowflake Score
Valuation2/6
Future Growth2/6
Past Performance0/6
Financial Health5/6
Dividends0/6

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Agios Pharmaceuticals, Inc. Competitors

Price History & Performance

Summary of share price highs, lows and changes for Agios Pharmaceuticals
Historical stock prices
Current Share PriceUS$28.60
52 Week HighUS$45.81
52 Week LowUS$22.40
Beta0.89
1 Month Change8.95%
3 Month Change-32.29%
1 Year Change-13.41%
3 Year Change-6.94%
5 Year Change-36.49%
Change since IPO-64.57%

Recent News & Updates

Recent updates

Shareholder Returns

0HB0GB BiotechsGB Market
7D0.9%2.0%1.3%
1Y-13.4%29.4%22.7%

Return vs Industry: 0HB0 underperformed the UK Biotechs industry which returned 29.4% over the past year.

Return vs Market: 0HB0 underperformed the UK Market which returned 22.7% over the past year.

Price Volatility

Is 0HB0's price volatile compared to industry and market?
0HB0 volatility
0HB0 Average Weekly Movement16.1%
Biotechs Industry Average Movement7.3%
Market Average Movement4.6%
10% most volatile stocks in GB Market10.8%
10% least volatile stocks in GB Market2.5%

Stable Share Price: 0HB0's share price has been volatile over the past 3 months compared to the UK market.

Volatility Over Time: 0HB0's weekly volatility has increased from 10% to 16% over the past year.

About the Company

FoundedEmployeesCEOWebsite
2007487Brian Goffwww.agios.com

Agios Pharmaceuticals, Inc., a biopharmaceutical company, discovers and develops medicines in the field of cellular metabolism in the United States. Its lead product includes PYRUKYND (mitapivat), an activator of wild-type and mutant pyruvate kinase (PK), enzymes used for the treatment of hemolytic anemias in adults with PK deficiency. The company’s PYRUKYND product also used for the treatment of sickle cell disease that is in phase 3 clinical trial; for the treatment of PK deficiency in pediatric patients; and for the treatment of adult patients with non-transfusion dependent and transfusion-dependent alpha- or beta-thalassemia.

Agios Pharmaceuticals, Inc. Fundamentals Summary

How do Agios Pharmaceuticals's earnings and revenue compare to its market cap?
0HB0 fundamental statistics
Market capUS$1.68b
Earnings (TTM)-US$401.26m
Revenue (TTM)US$44.79m
37.4x
P/S Ratio
-4.2x
P/E Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
0HB0 income statement (TTM)
RevenueUS$44.79m
Cost of RevenueUS$340.02m
Gross Profit-US$295.22m
Other ExpensesUS$106.04m
Earnings-US$401.26m

Last Reported Earnings

Sep 30, 2025

Next Earnings Date

n/a

Earnings per share (EPS)-6.88
Gross Margin-659.11%
Net Profit Margin-895.86%
Debt/Equity Ratio0%

How did 0HB0 perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/01/15 19:34
End of Day Share Price 2026/01/15 00:00
Earnings2025/09/30
Annual Earnings2024/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Agios Pharmaceuticals, Inc. is covered by 31 analysts. 10 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Peter LawsonBarclays
George FarmerBMO Capital Markets Equity Research
Alec StranahanBofA Global Research