Regulus Therapeutics Ownership

Who are the major shareholders and have insiders been buying or selling?

Recent Insider Transactions

DB:7RG0 Recent Insider Transactions by Companies or Individuals
Date	Value	Name	Entity	Role	Shares	Max Price
25 Jul 24	Buy€6,704	Kathryn Collier	Individual		4,000	€1.68
18 Jan 24	Sell€5,992	Crispina Calsada	Individual		5,468	€1.10

Insider Buying: Insufficient data to determine if insiders have bought more shares than they have sold in the past 3 months.

Dilution of Shares: Shareholders have been substantially diluted in the past year, with total shares outstanding growing by 223.9%.

Top 25 shareholders own 86.51% of the company

Ownership	Name	Shares	Current Value	Change %	Portfolio %
19.6%	Federated Hermes, Inc.	12,852,654	€18.6m	0%	0.04%
9.87%	New Enterprise Associates, Inc.	6,467,802	€9.4m	0%	0.41%
7.63%	Vivo Capital, LLC	5,000,000	€7.3m	0%	0.58%
6.51%	Octagon Capital Advisors LP	4,263,701	€6.2m	0%	1.0%
6.24%	The Vanguard Group, Inc.	4,088,760	€5.9m	0.94%	no data
6.23%	BlackRock, Inc.	4,081,038	€5.9m	2.83%	no data
4.98%	Deep Track Capital, LP	3,262,564	€4.7m	0%	0.14%
3.28%	T. Rowe Price Group, Inc.	2,151,071	€3.1m	10,400%	no data
3.05%	Adage Capital Management, L.P.	2,000,000	€2.9m	0%	0.01%
1.97%	Millennium Management LLC	1,291,415	€1.9m	6.24%	no data
1.96%	Geode Capital Management, LLC	1,280,567	€1.9m	-3.97%	no data
1.76%	Victory Capital Management Inc.	1,155,516	€1.7m	0%	no data
1.58%	Alyeska Investment Group, L.P.	1,037,500	€1.5m	10.7%	0.01%
1.53%	State Street Global Advisors, Inc.	1,000,998	€1.5m	3.46%	no data
1.49%	Stelios Papadopoulos	978,388	€1.4m	0%	no data
1.45%	Woodline Partners LP	948,702	€1.4m	0.11%	0.01%
1.37%	Dafna Capital Management, LLC	895,200	€1.3m	0%	0.33%
1.36%	Point72 Asset Management, L.P.	893,762	€1.3m	0%	no data
1.17%	RA Capital Management, L.P.	766,834	€1.1m	-87.7%	0.01%
0.82%	Opaleye Management Inc.	535,000	€776.2k	-63.7%	0.12%
0.76%	Northern Trust Global Investments	497,304	€721.5k	188%	no data
0.61%	Heights Capital Management, Inc.	401,012	€581.8k	0%	0.24%
0.5%	FMR LLC	328,157	€476.1k	-83.8%	no data
0.46%	TD Asset Management, Inc.	302,000	€438.2k	0%	no data
0.28%	Sarissa Capital Management LP	185,183	€268.7k	0%	0.07%