Spyre Therapeutics Ownership

Who are the major shareholders and have insiders been buying or selling?

Recent Insider Transactions

DB:3920 Recent Insider Transactions by Companies or Individuals
Date	Value	Name	Entity	Role	Shares	Max Price
03 Sep 24	Sell€472,895	Scott Burrows	Individual		18,531	€25.52

Insider Buying: 3920 insiders have only sold shares in the past 3 months.

Dilution of Shares: Shareholders have been substantially diluted in the past year, with total shares outstanding growing by 1349.9%.

Top 25 shareholders own 81.62% of the company

Ownership	Name	Shares	Current Value	Change %	Portfolio %
13%	FMR LLC	7,623,881	€200.5m	1.54%	0.01%
6.84%	Fairmount Funds Management LLC	4,018,101	€105.6m	0%	8.92%
6.05%	Peter Deutsch	3,550,276	€93.3m	825%	no data
5.55%	RTW Investments, LP	3,258,360	€85.7m	0%	1.21%
4.89%	Perceptive Advisors LLC	2,872,547	€75.5m	-5.23%	1.7%
4.57%	VR Adviser, LLC	2,685,448	€70.6m	0%	3.47%
4.54%	BlackRock, Inc.	2,663,147	€70.0m	10.8%	no data
4.29%	The Vanguard Group, Inc.	2,515,920	€66.2m	31.6%	no data
3.73%	Braidwell LP	2,189,836	€57.6m	-12.9%	2.58%
3.39%	Commodore Capital LP	1,988,084	€52.3m	0%	3.62%
2.63%	State Street Global Advisors, Inc.	1,541,555	€40.5m	9.36%	no data
2.57%	Wellington Management Group LLP	1,507,200	€39.6m	89.4%	0.01%
2.16%	Paradigm Biocapital Advisors LP	1,267,581	€33.3m	0%	1.21%
1.95%	Assenagon Asset Management S.A.	1,142,768	€30.0m	0%	0.05%
1.91%	Janus Henderson Group plc	1,120,531	€29.5m	66.3%	0.01%
1.8%	Adage Capital Management, L.P.	1,055,000	€27.7m	-8.45%	0.05%
1.7%	Deep Track Capital, LP	1,000,000	€26.3m	-43.1%	0.82%
1.52%	Geode Capital Management, LLC	891,048	€23.4m	16.4%	no data
1.41%	Pictet Asset Management Limited	825,706	€21.7m	114%	0.02%
1.3%	Franklin Resources, Inc.	760,611	€20.0m	2.52%	0.01%
1.27%	Cameron Turtle	746,907	€19.6m	0%	no data
1.21%	Citadel Advisors LLC	707,586	€18.6m	0%	0.02%
1.19%	Tavistock Life Sciences	696,480	€18.3m	0%	1.21%
1.17%	Driehaus Capital Management LLC	687,080	€18.1m	0%	0.11%
1.02%	Avoro Capital Advisors LLC	598,600	€15.7m	-67.5%	0.22%