Spero Therapeutics Ownership

Who are the major shareholders and have insiders been buying or selling?

Recent Insider Transactions

DB:2HA Recent Insider Transactions by Companies or Individuals
Date	Value	Name	Entity	Shares	Max Price
05 Feb 25	Sell€51,826	Ankit Mahadevia	Individual	69,219	€0.75
05 Feb 25	Sell€42,330	Timothy Keutzer	Individual	56,537	€0.75
05 Feb 25	Sell€116,301	Satyavrat Shukla	Individual	155,333	€0.75
05 Feb 25	Sell€15,490	Esther Rajavelu	Individual	20,689	€0.75
08 Nov 24	Sell€49,414	Esther Rajavelu	Individual	40,596	€1.22
27 Aug 24	Sell€3,334	Satyavrat Shukla	Individual	2,757	€1.21
27 Aug 24	Sell€2,676	Timothy Keutzer	Individual	2,213	€1.21
27 Aug 24	Sell€7,149	Ankit Mahadevia	Individual	5,912	€1.21
05 Aug 24	Sell€38,867	Satyavrat Shukla	Individual	32,441	€1.20

Insider Trading Volume

Insider Buying: 2HA insiders have only sold shares in the past 3 months.

Ownership Breakdown

What is the ownership structure of 2HA?
Owner Type	Number of Shares	Ownership Percentage
Individual Insiders	973,599	1.79%
Hedge Funds	3,750,450	6.88%
Institutions	8,486,764	15.6%
VC/PE Firms	9,190,606	16.9%
General Public	32,116,746	58.9%

Dilution of Shares: Shareholders have not been meaningfully diluted in the past year.

Top Shareholders

Top 25 shareholders own 40.4% of the company

Ownership	Name	Shares	Current Value	Change %	Portfolio %
16.9%	SR One Capital Management, LP	9,190,606	€7.1m	0%	1.92%
6.88%	Anson Group	3,750,450	€2.9m	0%	0.39%
3.23%	The Vanguard Group, Inc.	1,763,620	€1.4m	-0.39%	no data
1.97%	Acadian Asset Management LLC	1,071,860	€822.9k	0%	no data
1.79%	Renaissance Technologies LLC	974,653	€748.3k	-0.13%	no data
1.63%	GV Management Company, LLC	889,979	€683.3k	0%	0.04%
1.36%	ADAR1 Capital Management, LLC	743,459	€570.8k	-19.1%	0.12%
0.89%	BlackRock, Inc.	485,352	€372.6k	0.11%	no data
0.88%	Geode Capital Management, LLC	481,187	€369.4k	-2.23%	no data
0.86%	Novo Holdings A/S	468,902	€360.0k	0%	no data
0.64%	Ankit Mahadevia	350,812	€269.3k	50.2%	no data
0.61%	AWM Investment Company Inc	333,400	€256.0k	0%	0.03%
0.56%	Atlas Venture L.P.	305,255	€234.4k	-24.2%	0.04%
0.34%	Bridgeway Capital Management, LLC	184,800	€141.9k	0%	no data
0.27%	Timothy Keutzer	147,003	€112.9k	117%	no data
0.24%	State Street Global Advisors, Inc.	130,511	€100.2k	0%	no data
0.23%	Satyavrat Shukla	127,852	€98.2k	243%	no data
0.23%	Dafna Capital Management, LLC	125,000	€96.0k	0%	0.03%
0.22%	Kamal Hamed	121,418	€93.2k	0%	no data
0.2%	Northern Trust Global Investments	111,497	€85.6k	-0.72%	no data
0.15%	Citadel Advisors LLC	81,425	€62.5k	-73.9%	no data
0.11%	Tamara Joseph	61,378	€47.1k	0%	no data
0.081%	Susquehanna International Group, LLP, Asset Management Arm	44,219	€33.9k	91.7%	no data
0.08%	Esther Rajavelu	43,682	€33.5k	0%	no data
0.071%	Numeric Investors LLC	38,481	€29.5k	-47.6%	no data

Company Analysis and Financial Data Status

Data	Last Updated (UTC time)
Company Analysis	2025/02/11 11:00
End of Day Share Price	2025/02/11 00:00
Earnings	2024/09/30
Annual Earnings	2023/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

Package	Data	Timeframe	Example US Source ^*
Company Financials	10 years	Income statement Cash flow statement Balance sheet	SEC Form 10-K SEC Form 10-Q
Analyst Consensus Estimates	+3 years	Forecast financials Analyst price targets	Analyst Research Reports Blue Matrix
Market Prices	30 years	Stock prices Dividends, Splits and Actions	ICE Market Data SEC Form S-1
Ownership	10 years	Top shareholders Insider trading	SEC Form 4 SEC Form 13D
Management	10 years	Leadership team Board of directors	SEC Form 10-K SEC Form DEF 14A
Key Developments	10 years	Company announcements	SEC Form 8-K

^* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

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Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Spero Therapeutics, Inc. is covered by 9 analysts. 2 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

Analyst	Institution
Esther Lannie Hong	Berenberg
Jason Matthew Gerberry	BofA Global Research
Joshua Schimmer	Evercore ISI