Announcement • 13h
Oxford Nanopore Technologies plc Announces Executive Appointments Oxford Nanopore Technologies plc announced the appointments of Davide Manissero MD as Chief Medical Officer and Andrew Watson as Chief Information Officer. As Oxford Nanopore's first Chief Medical Officer, Davide will lead the Company's global clinical strategy leveraging his considerable experience across regulated clinical environments. Davide joins from Radiometer (a Danaher company), where he is currently CMO. He previously served as CMO at QIAGEN, leading global medical and clinical affairs, and held roles at ECDC and the WHO focused on infectious diseases and public health. Andrew Watson will lead the Company's information systems, data, digital transformation, machine learning, and product software development. Andrew joins from Mimecast, where he leads AI and threat protection engineering. He has previously held senior roles at Healx and Dyson, where he established machine learning and biomedical research teams. Andrew Watson and Davide Manissero join the Company on June 15, 2026 and August 3, 2026 respectively. Their appointments follow the announcement that Tina St Leger will join Oxford Nanopore as Chief People Officer in June 2026. Davide, Andrew and Tina will join the Executive team. In accordance with UK Listing Rule 6.4.6(3), the Company notes that responsibility for the commercial function will transfer from Nick Keher, CFO, to Francis Van Parys, CEO, effective 1 July 2026. Announcement • May 22
Oxford Nanopore Technologies plc Presents Technology Update At Annual Customer Conference Oxford Nanopore Technologies plc presented a Technology Update at the Company's flagship annual London Calling customer conference. Opening London Calling 2026, the Company highlighted continued focus on customer-led platform development, strengthening the user end-to-end experience and supporting broader adoption in applied and regulated environments. At the Annual Technology Talk the Company highlighted updates including: Platform development led by customer need. Delivering richer multiomic insight from a single platform: advances in integrated DNA, RNA and epigenetic data, including methylation, providing comprehensive insight from a single system. Driving continuous improvement in platform performance, including accuracy, base modifications, output and speed, with continued enhancement of unique features such as adaptive sampling. This includes the introduction of the PromethION Plus Flow Cell, designed to increase output with enhanced yield achieved without additional wash and reload steps. The Company also highlighted increasing use of AI-driven methods across basecalling, variant detection and downstream analysis. Expanding platform capability across core workflows, including transcriptomics (RNA), microbial and vaccine QC (GridION Q), and high-output sequencing (PromethION), with new chemistry and workflows shipping from May to July 2026. Regulatory readiness. Advancing reliability and consistency: improvements in repeatability and robust performance in production environments, enabling predictable use at scale. Expanding real-world deployment across routine and regulated settings. End-to-end experience. Simplifying workflows and reducing complexity to support broader adoption. Advancing integrated software platforms, including EPI2ME, for accessible and standardised data interpretation. Longer-term innovation and platform pipeline. Continuing investment across chemistry and hardware towards both low and high output applications, and development of multiomic capability including protein sequencing, extending the platform into new areas of biological insight. Showcasing a novel demonstration of peptide sequencing using an amino-acid calling for accurate protein identification. A video replay of the Technology Talk is available on the Oxford Nanopore website. Reported Earnings • May 05
Full year 2025 earnings: EPS misses analyst expectations Full year 2025 results: UK£0.15 loss per share (improved from UK£0.16 loss in FY 2024). Revenue: UK£223.9m (up 22% from FY 2024). Net loss: UK£145.2m (flat on FY 2024). Revenue was in line with analyst estimates. Earnings per share (EPS) missed analyst estimates by 1.5%. Revenue is forecast to grow 18% p.a. on average during the next 3 years, compared to a 18% growth forecast for the Life Sciences industry in the United Kingdom. Over the last 3 years on average, earnings per share has fallen by 3% per year but the company’s share price has fallen by 21% per year, which means it is performing significantly worse than earnings. 
