ENXTBR:ARGXBiotechs
Why argenx (ENXTBR:ARGX) Is Down 7.7% After Halting Its Phase 3 Thyroid Eye Disease Trials
On 15 December 2025, argenx SE said it would discontinue its Phase 3 UplighTED trials of subcutaneous efgartigimod in adults with moderate to severe thyroid eye disease after an Independent Data Monitoring Committee found the study was unlikely to meet its efficacy goals, despite a favorable safety profile and no new safety signals.
The company now plans a full analysis of the interim data to understand why the drug underperformed on proptosis response and other endpoints, and to extract...