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Leadership Return And Clinical Strength Will Drive Long-Term Market Opportunity

Published
01 Apr 25
Updated
10 Dec 25
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AnalystConsensusTarget's Fair Value
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1Y
-61.5%
7D
30.2%

Author's Valuation

US$5.7557.2% undervalued intrinsic discount

AnalystConsensusTarget Fair Value

Last Update 10 Dec 25

LUNG: Returning Leadership Will Drive Confidence And Unlock Significant Upside Ahead

Analysts have reduced their price target on Pulmonx to about $4 from roughly $8, citing a lower discount rate along with confidence in returning leadership, robust clinical validation of Zephyr valves, and a solid market and pipeline opportunity that they still see as supporting substantial upside from current levels.

Analyst Commentary

Bullish Takeaways

  • Bullish analysts highlight that the lowered price target still implies meaningful upside from current trading levels, suggesting the market may be underestimating the company’s long term earnings potential.
  • The return of prior leadership is viewed as a stabilizing factor that could accelerate execution on commercial strategy and operational efficiency, supporting a re rating over time.
  • Extensive clinical validation and proof of concept for Zephyr valves underpin confidence in durable demand, giving analysts comfort around long term revenue growth assumptions.
  • A growing addressable market and developing product pipeline are seen as key drivers for sustained top line expansion, helping justify a premium multiple despite near term volatility.

Bearish Takeaways

  • Bearish analysts view the reduced price target as a signal that risk adjusted growth expectations have moderated, with a higher hurdle for the company to meet prior valuation levels.
  • The leadership changes, while potentially positive, introduce transition risk around near term execution and guidance credibility, which could cap multiple expansion.
  • Despite strong clinical data, adoption curves and reimbursement dynamics remain key uncertainties, limiting visibility into how quickly the company can scale revenue to match bullish projections.
  • Margin improvement and cash utilization remain under scrutiny, with concerns that slower than expected operating leverage could constrain valuation upside even if revenue grows.

What's in the News

  • Pulmonx issued full year 2025 guidance, projecting total revenue of $89 million to $90 million and an expected gross margin of approximately 73% (company guidance filing).
  • The company provided third quarter 2025 revenue guidance, anticipating worldwide revenue of about $21.5 million (company guidance filing).
  • Chief Executive Officer Steven S. Williamson resigned effective October 27, 2025. He will remain in an advisory role through December 1, 2025 to support the leadership transition (company announcement).
  • The Board appointed longtime director and former CEO Glendon E. French as President and Chief Executive Officer, reinstating him to the role he held from 2014 to 2024 (company announcement).
  • Chief Financial Officer Mehul Joshi resigned effective October 27, 2025. Former Pulmonx CFO Derrick Sung, Ph.D., will return to the company as CFO effective November 3, 2025 (company announcement).

Valuation Changes

  • Fair Value: Unchanged at $5.75 per share, indicating no adjustment to the intrinsic value estimate.
  • Discount Rate: Fallen slightly from 9.73% to 9.03%, reflecting a modest reduction in perceived risk or cost of capital.
  • Revenue Growth: Essentially unchanged at about 16.8%, suggesting stable long term growth expectations.
  • Net Profit Margin: Fallen slightly from approximately 13.38% to 12.91%, pointing to a modestly more conservative profitability outlook.
  • Future P/E: Risen slightly from about 17.5x to 17.8x, implying a marginally higher valuation multiple on projected earnings.

Key Takeaways

  • Increased early detection, demographic trends, and strategic partnerships are expanding the patient base and supporting sustained demand and revenue growth for Pulmonx.
  • Clinical validation, reimbursement stability, and geographic expansion are driving broader adoption, improving margins, and strengthening Pulmonx's earnings stability and growth prospects.
  • Heavy reliance on a limited product range, operational bottlenecks, and external uncertainties threaten Pulmonx's growth prospects, profitability, and resilience against shifting market dynamics.

Catalysts

About Pulmonx
    A commercial-stage medical technology company that provides a minimally invasive treatment for patients with severe emphysema, a form of chronic obstructive pulmonary disease.
What are the underlying business or industry changes driving this perspective?
  • Increased awareness and early detection through expanded lung cancer screening infrastructure and the adoption of tools like LungTraX Detect are driving more severe emphysema patients into the treatment funnel, setting the stage for future acceleration in revenue as procedure conversion rates improve.
  • Strong global demographic trends-an aging population and rising prevalence of COPD-are continually expanding Pulmonx's total addressable market, which supports sustained long-term demand for Zephyr Valves and underpins ongoing revenue growth.
  • The company's ecosystem-building approach, including partnerships (i.e., with Jaeger for pulmonary function testing), hospital integration, and direct-to-patient outreach, is unlocking alternative referral channels that will broaden patient access and could accelerate top-line growth and utilization rates over time.
  • Continued clinical validation and positive real-world data for Zephyr Valves, combined with stable reimbursement, are poised to drive higher physician adoption and support further improvements in gross margins and earnings as scale is achieved and production costs are optimized.
  • Geographic expansion, particularly success in international direct markets and the path toward commercialization in underpenetrated regions like Japan, will diversify revenue streams and improve earnings stability, mitigating risks tied to any single geographic region.

Pulmonx Earnings and Revenue Growth

Pulmonx Future Earnings and Revenue Growth

Assumptions

How have these above catalysts been quantified?
  • Analysts are assuming Pulmonx's revenue will grow by 17.3% annually over the next 3 years.
  • Analysts are not forecasting that Pulmonx will become profitable in next 3 years. To represent the Analyst Price Target as a Future PE Valuation we will estimate Pulmonx's profit margin will increase from -62.9% to the average US Medical Equipment industry of 12.5% in 3 years.
  • If Pulmonx's profit margin were to converge on the industry average, you could expect earnings to reach $18.3 million (and earnings per share of $0.42) by about September 2028, up from $-56.9 million today.
  • In order for the above numbers to justify the analysts price target, the company would need to trade at a PE ratio of 21.2x on those 2028 earnings, up from -1.2x today. This future PE is lower than the current PE for the US Medical Equipment industry at 28.6x.
  • Analysts expect the number of shares outstanding to grow by 3.19% per year for the next 3 years.
  • To value all of this in today's terms, we will use a discount rate of 9.28%, as per the Simply Wall St company report.

Pulmonx Future Earnings Per Share Growth

Pulmonx Future Earnings Per Share Growth

Risks

What could happen that would invalidate this narrative?
  • Pulmonx's growth is currently constrained by bottlenecks in U.S. procedure volume, primarily due to operational pressures, slow conversion of new commercial initiatives, and healthcare provider capacity limitations-which could result in lower-than-expected revenue growth and continued net losses.
  • The company's business remains highly reliant on the Zephyr Valve and related narrow product portfolio; delays in successful diversification (e.g., with AeriSeal or further expanding AI-enabled diagnostics) expose Pulmonx to risk from technological obsolescence or shifts in clinical practice, threatening long-term revenue streams and margin stability.
  • Increasing dependence on complex workflows, multi-stakeholder engagement, and lengthy contracting cycles (particularly for new screening technologies like LungTrax Detect) could extend sales cycles, slow market penetration, and delay revenue realization, negatively affecting operating leverage and profitability.
  • Intense international growth, especially in distributor-driven markets with expected second-half moderation and near-term uncertainty (such as low ordering from China), may lead to revenue volatility, particularly as Pulmonx has little short-term control over these external distributor dynamics.
  • Persistently high operating expenses, increased R&D spending, and ongoing net losses-with only moderate guidance adjustments on cost and a relatively high cash burn rate-raise the risk that Pulmonx may struggle to achieve sustained profitability and positive earnings without a substantial and rapid acceleration in adoption and market penetration.

Valuation

How have all the factors above been brought together to estimate a fair value?
  • The analysts have a consensus price target of $6.75 for Pulmonx based on their expectations of its future earnings growth, profit margins and other risk factors. However, there is a degree of disagreement amongst analysts, with the most bullish reporting a price target of $16.0, and the most bearish reporting a price target of just $2.5.
  • In order for you to agree with the analyst's consensus, you'd need to believe that by 2028, revenues will be $146.3 million, earnings will come to $18.3 million, and it would be trading on a PE ratio of 21.2x, assuming you use a discount rate of 9.3%.
  • Given the current share price of $1.66, the analyst price target of $6.75 is 75.4% higher.
  • We always encourage you to reach your own conclusions though. So sense check these analyst numbers against your own assumptions and expectations based on your understanding of the business and what you believe is probable.

How well do narratives help inform your perspective?

Disclaimer

AnalystConsensusTarget is a tool utilizing a Large Language Model (LLM) that ingests data on consensus price targets, forecasted revenue and earnings figures, as well as the transcripts of earnings calls to produce qualitative analysis. The narratives produced by AnalystConsensusTarget are general in nature and are based solely on analyst data and publicly-available material published by the respective companies. These scenarios are not indicative of the company's future performance and are exploratory in nature. Simply Wall St has no position in the company(s) mentioned. Simply Wall St may provide the securities issuer or related entities with website advertising services for a fee, on an arm's length basis. These relationships have no impact on the way we conduct our business, the content we host, or how our content is served to users. The price targets and estimates used are consensus data, and do not constitute a recommendation to buy or sell any stock, and they do not take account of your objectives, or your financial situation. Note that AnalystConsensusTarget's analysis may not factor in the latest price-sensitive company announcements or qualitative material.

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