Verastem, Inc.

NasdaqCM:VSTM 주식 리포트

시가총액: US$364.7m

Verastem 경영진

경영진 기준 점검 4/4

Verastem CEO는 Dan Paterson, Jun2019 에 임명되었습니다 의 임기는 6.92 년입니다. 총 연간 보상은 $2.40M, 28.1% 급여 및 71.9% 보너스(회사 주식 및 옵션 포함)로 구성됩니다. 는 $946.70K 가치에 해당하는 회사 주식의 0.26% 직접 소유합니다. 경영진과 이사회의 평균 재임 기간은 2.3 년과 4.7 년입니다.

핵심 정보

Dan Paterson

최고경영자

US$2.4m

총 보수

CEO 급여 비율28.08%
CEO 재임 기간6.9yrs
CEO 지분 보유율0.3%
경영진 평균 재임 기간2.3yrs
이사회 평균 재임 기간4.7yrs

최근 경영진 업데이트

Recent updates

분석 기사 May 11

Analysts Are Updating Their Verastem, Inc. (NASDAQ:VSTM) Estimates After Its First-Quarter Results

It's been a sad week for Verastem, Inc. ( NASDAQ:VSTM ), who've watched their investment drop 18% to US$4.89 in the...
새로운 내러티브 Jan 22

RAS And MAPK Cancer Pipeline Will Drive Long Term Upside Potential

Catalysts About Verastem Verastem is an oncology company focused on therapies for RAS and MAPK pathway driven cancers, including KRAS mutated recurrent low grade serous ovarian cancer. What are the underlying business or industry changes driving this perspective?
분석 기사 Dec 26

Verastem, Inc.'s (NASDAQ:VSTM) Share Price Is Still Matching Investor Opinion Despite 26% Slump

Verastem, Inc. ( NASDAQ:VSTM ) shareholders won't be pleased to see that the share price has had a very rough month...
Seeking Alpha Jul 16

Verastem: The Market Is Ignoring The Progress

Summary FDA approval of AVMAPKI FAKZYNJA CO-PACK marks a transformative milestone, positioning Verastem as a commercial-stage leader in KRAS-mutant LGSOC treatment. Verastem's strong cash position and promising pipeline, including VS-7375 for KRAS G12D, offer significant upside with multiple near-term catalysts ahead. Risks include slow commercial uptake, pipeline uncertainty, and potential future dilution, but current valuation under $5 presents an attractive entry point. I maintain a 3/5 conviction, plan to add to my position below $5.75, and aim to hold long-term as VSTM targets KRAS-driven cancers. Read the full article on Seeking Alpha
Seeking Alpha May 26

Verastem: Narrowed Market And Less Compelling Efficacy Warrant Rating Downgrade

Summary Verastem's stock plummeted after updates showed reduced efficacy in cancer treatment trials, causing a reassessment of strategy. Updated clinical trial results show a significant drop in response rates, suggesting less robust efficacy than earlier believed. Financially, Verastem has only a year of cash runway and faces significant dilution risks to extend it. Downgrade the recommendation to 'hold' due to increased risks and market volatility associated with microcap stocks. Read the full article on Seeking Alpha
Seeking Alpha Sep 13

Verastem: Moving Forward

Summary Today, we circle back on a small oncology outfit called Verastem, Inc. The company is steadily advancing its pipeline targeting both LGSOC and NSCLC and Verastem secured funding this year to carry out its multiple trials. An investment analysis follows in the paragraphs below. Don't waste your time with explanations: people only hear what they want to hear. ― Paulo Coelho We haven't taken a look at Verastem, Inc. (NASDAQ:VSTM) since an article on this small biotech name early last year. There has been some news flow around the company since then and Verastem recently posted a new investor presentation, so it seems a good time to circle back on this story. Seeking Alpha Company Overview Verastem is based out of Massachusetts. The company developed 'Copiktra' which received FDA approval for chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL)/follicular lymphoma in the summer of 2018. The company soon after sold the global rights to this compound for a significant upfront payment. It continues to collect royalties and milestone payments from this arrangement. August Company Presentation The company is currently focused on establishing its candidate 'VS-6766' as the backbone therapy for RAS-driven solid tumors. This is how management describes VS-6766 on its last earnings press release. August Company Presentation VS-6766 is a RAF/MEK clamp that induces inactive complexes of MEK with ARAF, BRAF and CRAF potentially creating a more complete and durable anti-tumor response through maximal RAS pathway inhibition. In contrast to other MEK inhibitors, VS-6766 blocks both MEK kinase activity and the ability of RAF to phosphorylate MEK. This unique mechanism allows VS-6766 to block MEK signaling without the compensatory activation of MEK that appears to limit the efficacy of other inhibitors. August Company Presentation There is a high unmet need in the cancers VS-6766 is targeting in development. The stock currently trades around $1.25 a share and sports an approximate market capitalization of $230 million. August Company Presentation Developmental Progress August Company Presentation As can be seen above, VS-6766 is in numerous combination therapy trials and as a monotherapy focused on Non-Small Cell Lung Cancer (NSCLC) and Gynecologic Oncology. Most of these studies pair VS-6766 with another Verastem pipeline asset Defactinib, a FAK inhibitor. The most critical of these are RAMP 201 and RAMP 202. Both are registration-directed phase 2 studies and were initiated in the fourth quarter of 2020. RAMP 201 is targeting low-grade serous ovarian carcinoma or LGSOC and RAMP 2022 is targeting NSCLC. August Company Presentation Both studies should see top line results out in 2023. In mid-June, interim results came out from the RAMP 201 trial that showed VS-6766 as both a standalone therapy and in combination with defactinib showed encouraging efficacy with confirmed responses in patients with recurrent LGSOC, regardless of KRAS mutation. August Company Presentation The company is also conducting a trial called RAMP 203 in conjunction with Amgen (AMGN). This phase 1/2 with evaluate the 'tolerability and efficacy of VS-6766 in combination with Lumakras in patients with KRAS G12C-mutant NSCLC who have not been previously treated with a KRAS G12C inhibitor as well as in patients who have progressed on a KRAS G12C inhibitor.'
분석 기사 Sep 01

Health Check: How Prudently Does Verastem (NASDAQ:VSTM) Use Debt?

Howard Marks put it nicely when he said that, rather than worrying about share price volatility, 'The possibility of...
Seeking Alpha Aug 08

Verastem Non-GAAP EPS of -$0.11 in-line

Verastem press release (NASDAQ:VSTM): Q2 Non-GAAP EPS of -$0.11 in-line. Verastem Oncology ended the second quarter 2022 with cash, cash equivalents and investments of $94.3 million. With proceeds available upon achievement of certain milestones from the Oxford Finance LLC credit facility and expected milestones and royalties from the sale of COPIKTRA, Verastem Oncology expects that it has a cash runway until at least 2025 to deliver on the current programs for VS-6766 and defactinib, including expenditures and development in LGSOC and KRAS mutant NSCLC. Shares +2.52% PM.
Seeking Alpha Jun 29

Verastem: Looking Increasingly Attractive

Verastem's RAF/MEK/FAK inhibitor program is progressing nicely. They are releasing decent data with no sudden surprises. They have strengthened their cash position non-dilutively. Verastem’s (VSTM) strategy is to buy big pharma cast-offs on the cheap, and then run them through the clinical and regulatory process. This lets them skip the discovery process altogether, sometimes even the earlier stage trials. There’s no harm in the strategy, except that it hasn’t been so successful with duvelisib. That asset didn’t sell well, and was sold off for $70mn. With that fund, they purchased two more assets - RAF/MEK dual inhibitor VS-6766 from Chugai and Defactinib, an FAK inhibitor. As I said before: VS-6766 has unique properties. Not only does it block MEK activity, but it also stops RAF from phosphorylating MEK. Thus, VS-6766 is able to block MEK signaling while avoiding compensatory activation of MEK which limits the efficacy of just MEK inhibitors. Last year, the company began two registration-directed phase 2 studies in LGSOC and NSCLC, respectively, where LGSOC is low-grade serous ovarian carcinoma and NSCLC is non-small cell lung cancer. These trials pit VS-6766 versus VS-6766 + Defactinib in these two cancers with or without KRAS mutation for the recurrent low grade LGSOC trial, and Recurrent G12V or Other KRAS-Mutant NSCLC, respectively. Both trials will topline in 2023. One important point noted in earlier trials is that VS-6766 inhibits MEK phosphorylation, unlike other RAF/MEK inhibitors; this is good because MEK phosphorylation may cause unwanted cellular processes. For example, “Lee et al (91) showed that the rates of MEK phosphorylation in colon cancer, villous adenoma and tubular adenoma were 76, 40 and 30%, respectively, while the phosphorylation of MEK in normal colonic mucosal cells was barely detectable.” This tells us that MEK phosphorylation may be responsible for tumorigenesis, tumor cell survival and proliferation. Another datapoint is interim data from the FRAME study published last year in patients with low-grade serous ovarian cancer ((LGSOC)). An ORR of 56% was observed in this analysis so far, in patients with KRAS-G12 mutant LGSOC, and a 41% ORR in the overall LGSOC population. Updated data presented at ESMO last year showed the following: Among the evaluable patients with LGSOC (n=24), the overall response rate (ORR) was 46% (11 of 24). Among the patients with KRAS mutant LGSOC (n=11) and KRAS wild type LGSOC (n=9), the ORR was 64% (7 of 11) and 44% (4 of 9), respectively. The median progression-free survival (mPFS) across all patients was 23.0 months (95% CI: 10.6- not reached). This high ORR in KRAS-mutant cancer proves the clinical thesis behind the molecule to a large degree. They also beat historical ORR standards by a very large margin. Even with MEK inhibitors, data was poor: The initial phase II trial examined selumetinib in recurrent LGSOC.19 The objective response rate ((ORR)) was 15%, with 65% of patients having stable disease, and median progression-free survival ((PFS)) was 11.0 months. DNA from 34 patients was analyzed for KRAS and BRAF mutations. There were two BRAF mutations (6%) and 14 KRAS mutations (41%); however, no correlation between response and mutational status was found. Another dataset from the MILO trial comparing binimetinib with physician’s choice of chemotherapy ((PCC)): In the MILO trial, the ORR by BICR was 16% for binimetinib and 13% for PCC; however, in the updated analysis, the ORR by local investigator assessment was 24% in both groups. In GOG 0281, the ORRs were 26% and 6.2% for trametinib and PCC, respectively. Both selumetinib and binimetinib are MEK inhibitors, whereas VS-6766 is a dual MEK/RAF inhibitor.

CEO 보수 분석

Dan Paterson의 보수는 Verastem의 수익에 비해 어떻게 변했나요?
날짜총 보수급여회사 수익
Mar 31 2026n/an/a

-US$194m

Dec 31 2025US$2mUS$674k

-US$209m

Sep 30 2025n/an/a

-US$241m

Jun 30 2025n/an/a

-US$167m

Mar 31 2025n/an/a

-US$149m

Dec 31 2024US$3mUS$648k

-US$131m

Sep 30 2024n/an/a

-US$93m

Jun 30 2024n/an/a

-US$89m

Mar 31 2024n/an/a

-US$106m

Dec 31 2023US$4mUS$545k

-US$87m

Sep 30 2023n/an/a

-US$77m

Jun 30 2023n/an/a

-US$75m

Mar 31 2023n/an/a

-US$73m

Dec 31 2022US$698kUS$470k

-US$74m

Sep 30 2022n/an/a

-US$73m

Jun 30 2022n/an/a

-US$78m

Mar 31 2022n/an/a

-US$73m

Dec 31 2021US$2mUS$460k

-US$71m

Sep 30 2021n/an/a

-US$75m

Jun 30 2021n/an/a

-US$39m

Mar 31 2021n/an/a

-US$45m

Dec 31 2020US$2mUS$467k

-US$68m

Sep 30 2020n/an/a

-US$87m

Jun 30 2020n/an/a

-US$130m

Mar 31 2020n/an/a

-US$149m

Dec 31 2019US$2mUS$445k

-US$149m

보상 대 시장: Dan의 총 보수(USD2.40M)는 US 시장에서 비슷한 규모 기업의 평균(USD2.72M) 수준입니다.

보상과 수익: Dan의 보상은 지난 1년 동안 회사 실적과 일치했습니다.


CEO

Dan Paterson (64 yo)

6.9yrs
재임 기간
US$2,400,525
보수

Mr. Daniel W. Paterson, also known as Dan, serves as Chief Executive Officer Verastem, Inc. since August 1, 2023 and is its President of Verastem, Inc. since June 2019. He is Director of Verastem, Inc. sin...


리더십 팀

이름직위재임 기간보수지분
Daniel Paterson
President6.9yrsUS$2.40m0.26%
$ 946.7k
Daniel Calkins
Chief Financial Officer3.6yrsUS$976.87k0.060%
$ 219.8k
Michael Kauffman
President of Development & Directorless than a yearUS$1.21m0.017%
$ 62.8k
Robert Weinberg
Co-Founder & Chair of Scientific Advisory Boardno data데이터 없음데이터 없음
Michelle Detwiler
Co-Founderno data데이터 없음데이터 없음
Lori Horvat
Executive Vice President of Portfolio Strategy & Operationsless than a year데이터 없음데이터 없음
Jonathan Pachter
Chief Scientific Officer10.1yrsUS$319.51k데이터 없음
Julissa Viana
Vice President of Corporate Communications & Investor Relationsno data데이터 없음데이터 없음
Mark Wanda
Senior VP of Legal & Chief Compliance Officerless than a year데이터 없음데이터 없음
Cathy Carew
Chief Organizational Effectiveness Officerno data데이터 없음데이터 없음
Nathan Sanburn
Chief Business Officer2.3yrs데이터 없음데이터 없음
Colleen Mockbee
Global Head of Regulatory Affairs & Development2.3yrs데이터 없음데이터 없음
2.3yrs
평균 재임 기간
62yo
평균 나이

경험이 풍부한 관리: VSTM의 경영진은 경험이 있음으로 간주됩니다(평균 재임 2.3 년).


이사회 구성원

이름직위재임 기간보수지분
Daniel Paterson
President2.8yrsUS$2.40m0.26%
$ 946.7k
Michael Kauffman
President of Development & Director13.5yrsUS$1.21m0.017%
$ 62.8k
Robert Weinberg
Co-Founder & Chair of Scientific Advisory Boardno data데이터 없음데이터 없음
Mario Sznol
Member of Scientific Advisory Boardno data데이터 없음데이터 없음
Paul A. Bunn
Independent Director4.9yrsUS$192.99k0.017%
$ 60.5k
Eric Rowinsky
Independent Director9yrsUS$214.99k0.015%
$ 54.7k
John Johnson
Independent Chairman6.1yrsUS$199.99k0.017%
$ 60.5k
Robert Gagnon
Director3.4yrsUS$182.99k0.045%
$ 164.3k
Channing Der
Member of Scientific Advisory Board4.2yrs데이터 없음데이터 없음
Brian Stuglik
Director8.7yrsUS$202.99k0.11%
$ 411.1k
Anil Kapur
Independent Director3.6yrsUS$209.99k0.017%
$ 60.5k
Michelle Robertson
Independent Director4.5yrsUS$202.99k0.017%
$ 60.5k
4.7yrs
평균 재임 기간
65yo
평균 나이

경험이 풍부한 이사회: VSTM의 이사회경험이 있음으로 간주됩니다(평균 재임 4.7 년).


기업 분석 및 재무 데이터 상태

데이터최종 업데이트 (UTC 시간)
기업 분석2026/05/20 12:02
종가2026/05/20 00:00
수익2026/03/31
연간 수익2025/12/31

데이터 소스

당사의 기업 분석에 사용되는 데이터는 S&P Global Market Intelligence LLC에서 제공됩니다. 아래 데이터는 이 보고서를 생성하기 위해 분석 모델에서 사용됩니다. 데이터는 정규화되므로 소스가 제공된 후 지연이 발생할 수 있습니다.

패키지데이터기간미국 소스 예시 *
기업 재무제표10년
  • 손익계산서
  • 현금흐름표
  • 대차대조표
분석가 컨센서스 추정치+3년
  • 재무 예측
  • 분석가 목표주가
시장 가격30년
  • 주가
  • 배당, 분할 및 기타 조치
지분 구조10년
  • 주요 주주
  • 내부자 거래
경영진10년
  • 리더십 팀
  • 이사회
주요 개발10년
  • 회사 공시

* 미국 증권에 대한 예시이며, 비(非)미국 증권에는 해당 국가의 규제 서식 및 자료원을 사용합니다.

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분석가 소스

Verastem, Inc.는 28명의 분석가가 다루고 있습니다. 이 중 9명의 분석가가 우리 보고서에 입력 데이터로 사용되는 매출 또는 수익 추정치를 제출했습니다. 분석가의 제출 자료는 하루 종일 업데이트됩니다.

분석가기관
James MolloyAlliance Global Partners
Matthew CrossAlliance Global Partners
George ZavoicoB. Riley Securities, Inc.