공시 • 5m
4basebio PLC, Annual General Meeting, Jun 30, 2026 4basebio PLC, Annual General Meeting, Jun 30, 2026. Location: the offices of 4basebio plc, United Kingdom 공시 • May 12
4basebio PLC Launches Enzymatic ssDNA Platform 4basebio PLC announced the commercial launch of its high-capacity single-stranded DNA (ssDNA) product line to accelerate the development of safer, more precise genetic therapies by enabling targeted gene editing, advanced cell engineering, and innovative nucleic acid-based medicines. Built on a proprietary enzymatic manufacturing process, the platform provides biopharma with high-purity, long-form ends protected ssDNA templates, designed to overcome critical manufacturing and performance bottlenecks associated with traditional chemical synthesis in CRISPR-based gene editing, enabling large-scale, clinically viable therapeutics. With the growth of gene editing and with a particular need for complex "knock-in" applications, the demand for longer, purer and safer DNA templates has increased exponentially. 4basebio’s ssDNA offering enables the production of constructs up to 10,000 nucleotides with protected ends, ensuring stability, reduced immunogenicity and a cleaner path to clinical manufacturing. The technical advantages of the platform will be showcased at the upcoming American Society of Gene & Cell Therapy (ASGCT) Annual Meeting in Boston, MA. Amine Bouchareb, Director of Molecular Biology and Gene Editing at 4basebio, will deliver a presentation titled "An enzymatic ssDNA platform addresses manufacturing and performance bottlenecks in non-viral CRISPR gene editing" on 14 May at 9:00 AM EDT. At ASGCT, I look forward to presenting data that demonstrates how our long-form ssDNA constructs significantly enhance Homology Directed Repair (HDR) gene editing efficiency while maintaining superior cell viability in sensitive primary cell types. This technology is the bridge between discovery-phase editing and large-scale clinical success. This announcement contains inside information for the purposes of Article 7 of EU Regulation 596/2014 as amended by regulation 11 of the Market Abuse (Amendment) (EU Exit) Regulations 2019/310. New Risk • May 07
New minor risk - Market cap size The company's market capitalization is less than US$100m. Market cap: UK£71.2m (US$96.6m) This is considered a minor risk. Companies with a small market capitalization are most likely businesses that have not yet released a product to market or are simply a very small company without a wide reach. Either way, risk is elevated with these companies because there is a chance the product may not come to fruition or the company's addressable market or demand may not be as large as expected. In addition, if the company's size is the main factor, it is less likely to have many investors and analysts following it and scrutinizing its performance and outlook. Currently, the following risks have been identified for the company: Major Risk Earnings have declined by 45% per year over the past 5 years. Minor Risks Latest financial reports are more than 6 months old (reported June 2025 fiscal period end). Shareholders have been diluted in the past year (21% increase in shares outstanding). Revenue is less than US$5m (UK£1.8m revenue, or US$2.4m). Market cap is less than US$100m (UK£71.2m market cap, or US$96.6m). New Risk • Apr 17
New minor risk - Financial data availability The company's latest financial reports are more than 6 months old. Last reported fiscal period ended June 2025. This is considered a minor risk. If the company has not reported its earnings on time, it may have been delayed due to audit problems or it may be finding it difficult to reconcile its accounts. Currently, the following risks have been identified for the company: Major Risk Earnings have declined by 45% per year over the past 5 years. Minor Risks Latest financial reports are more than 6 months old (reported June 2025 fiscal period end). Shareholders have been diluted in the past year (21% increase in shares outstanding). Revenue is less than US$5m (UK£1.8m revenue, or US$2.4m). New Risk • Mar 24
New minor risk - Market cap size The company's market capitalization is less than US$100m. Market cap: UK£74.0m (US$99.0m) This is considered a minor risk. Companies with a small market capitalization are most likely businesses that have not yet released a product to market or are simply a very small company without a wide reach. Either way, risk is elevated with these companies because there is a chance the product may not come to fruition or the company's addressable market or demand may not be as large as expected. In addition, if the company's size is the main factor, it is less likely to have many investors and analysts following it and scrutinizing its performance and outlook. Currently, the following risks have been identified for the company: Major Risk Earnings have declined by 45% per year over the past 5 years. Minor Risks Shareholders have been diluted in the past year (21% increase in shares outstanding). Revenue is less than US$5m (UK£1.8m revenue, or US$2.4m). Market cap is less than US$100m (UK£74.0m market cap, or US$99.0m). 
