View ValuationBasilea Pharmaceutica 향후 성장Future 기준 점검 1/6Basilea Pharmaceutica 의 수익은 연간 1.8% 감소할 것으로 예상되는 반면, 연간 수익은 4.9% 로 증가할 것으로 예상됩니다. EPS는 연간 2.6% 만큼 성장할 것으로 예상됩니다. 자기자본이익률은 3년 후 11.2% 로 예상됩니다.핵심 정보4.9%이익 성장률2.62%EPS 성장률Biotechs 이익 성장23.3%매출 성장률-1.8%향후 자기자본이익률11.21%애널리스트 커버리지Low마지막 업데이트14 Aug 2026최근 향후 성장 업데이트공고 • Feb 18+ 1 more updateBasilea Pharmaceutica AG Provides Earnings Guidance for the Full Year 2026Basilea Pharmaceutica AG provided earnings guidance for the full year 2026. For the year, the company expects total revenue of ~10% increase. Operating profit of ~20% increase.모든 업데이트 보기Recent updates공고 • Aug 06Basilea Pharmaceutica Ltd Receives Additional Funding to Continue Development of Novel Antibiotic Ceftibuten-Ledaborbactam EtzadroxilBasilea Pharmaceutica Ltd. has been awarded an additional USD 5.4 million of funding by the Biomedical Advanced Research and Development Authority (BARDA), part of the Administration for Strategic Preparedness and Response (ASPR) within the U.S. Department of Health and Human Services, to continue the development of the novel oral antibiotic ceftibuten-ledaborbactam etzadroxil, a beta-lactam/beta-lactamase inhibitor (BL/BLI) combination, for the treatment of complicated urinary tract infections (cUTIs), including pyelonephritis. After this additional funding of USD 5.4 million, a total of USD 30.8 million of funding has been awarded to Basilea by BARDA. The contract has the potential to provide a total of up to USD 172 million of non-dilutive funding, of which approximately USD 14 million relate to the period prior to novation of the contract to Basilea. Many Gram-negative bacteria express enzymes such as extended spectrum beta-lactamases (ESBL) that confer resistance against commonly used antibiotics. Beta-lactamase inhibitors block these enzymes and restore the activity of beta-lactam antibiotics against initially resistant Gram-negative bacteria, therefore BL/BLI combinations are an important addition to the armamentarium for the treatment of infections caused by multidrug-resistant bacterial pathogens. Ledaborbactam etzadroxil is the orally bioavailable prodrug of ledaborbactam, a novel broad-spectrum boronic acid beta-lactamase inhibitor, which is being developed in combination with ceftibuten, an oral cephalosporin antibiotic, which is approved in the US for the treatment of upper and lower respiratory tract infections and for urinary tract infections outside the US. In vitro and in vivo studies demonstrated that ledaborbactam etzadroxil restores the activity of ceftibuten against strains of Enterobacterales expressing Ambler class A extended spectrum beta-lactamases (ESBLs), class C cephalosporinases, and class A and D carbapenemases (KPC and OXA-48, respectively) as well as multidrug-resistant (MDR) Enterobacterales. Ceftibuten-ledaborbactam etzadroxil has been granted Qualified Infectious Disease Product (QIDP) and Fast Track designations by the US Food and Drug Administration (FDA) for cUTI and uncomplicated urinary tract infections. Ceftibuten-ledaborbactam etzadroxil is an investigational drug and is not yet approved in any country for commercial use. Complicated UTIs, which include pyelonephritis (kidney infections), are defined as urinary tract infections ascending from the bladder accompanied by local and systemic signs and symptoms and are one of the most common bacterial infections in hospital and community settings. Increasing resistance of bacteria causing complicated urinary tract infections has led to limited availability of effective oral antibiotic treatment options. Currently, there are no approved oral beta-lactam or beta-lactam/beta-lactamase inhibitor combinations that are effective against Enterobacterales expressing Ambler class A ESBLs, class C cephalosporinases, and class A & D serine carbapenemases (KPC and OXA-48).공고 • Jul 29Basilea Receives USD 30 Million Funding Under Existing BARDA Agreement for Advancing Phase 3 Development of Novel Antifungal FosmanogepixBasilea Pharmaceutica Ltd, Allschwil announced that the Biomedical Advanced Research and Development Authority (BARDA), part of the Administration for Strategic Preparedness and Response (ASPR) within the U.S. Department of Health and Human Services (HHS), awarded USD 30 million in additional funding to Basilea after meeting its prespecified enrollment milestone. The additional funding will continue to advance Basilea’s ongoing phase 3 program for the novel antifungal, fosmanogepix. The commitment is made under the “Other Transaction Agreement” (OTA, agreement number 75A50124C00033). The new tranche of USD 30 million comes in addition to the USD 93 million already committed by BARDA since the signing of the OTA in September 2024. BARDA’s financial contribution is about 60% of the total costs of the supported projects, fosmanogepix and BAL2062, including clinical and regulatory activities, over the term of the OTA, which could provide a total potential non-dilutive funding of up to approximately USD 268 million over up to 12 years, if all additional options to extend the contract are exercised by BARDA. Fosmanogepix is a first-in-class clinical-stage broad-spectrum antifungal. It has a novel mechanism of action and its active moiety has shown activity against common species of Candida and Aspergillus, including multi-drug-resistant strains, such as Candida auris and Candida glabrata, as well as rare difficult-to-treat molds including Fusarium spp., Scedosporium spp., and some fungi from the Mucorales order. Fosmanogepix intravenous and oral formulations have been evaluated in clinical phase 2 studies for the treatment of patients with Candidemia, including Candida auris infections, and invasive mold infections. The FAST study, a phase 3 study evaluating fosmanogepix in the treatment of adult patients with candidemia and/or invasive candidiasis and the FORWARD study, a phase 3 study, in the treatment of adult patients with invasive mold infections, are ongoing. Fosmanogepix has received Fast Track and Orphan Drug designations from the U.S. Food and Drug Administration for a number of indications, and is designated as a Qualified Infectious Disease Product (QIDP). BAL2062 is a first-in-class clinical-stage antifungal, derived from a natural product, and has demonstrated fungicidal activity against clinically important molds such as Aspergillus spp., including azole-resistant strains. Safety and tolerability have been demonstrated in a previously completed phase 1 study with single and multiple ascending intravenous (i.v.) doses. The drug candidate has Qualified Infectious Disease Product (QIDP), Orphan Drug and Fast Track designation from the US Food and Drug Administration (FDA) for invasive aspergillosis.공고 • May 28Basilea Pharmaceutica Ltd Receives Additional USD 13.3 Million From BARDA To Continue Development Of Novel Antibiotic Ceftibuten-Ledaborbactam EtzadroxilBasilea Pharmaceutica Ltd, Allschwil announced that the Biomedical Advanced Research and Development Authority (BARDA), part of the Administration for Strategic Preparedness and Response (ASPR) within the U.S. Department of Health and Human Services, awarded USD 13.3 million to Basilea to continue the development of Basilea’s novel oral antibiotic ceftibuten-ledaborbactam etzadroxil, a beta-lactam/beta-lactamase inhibitor (BL/BLI) combination, for the treatment of complicated urinary tract infections (cUTIs), including pyelonephritis. After the current tranche of USD 13.3 million, a total of USD 25 million have been committed by BARDA. The contract could provide up to USD 133 million of additional non-dilutive funding. Many Gram-negative bacteria express enzymes such as extended spectrum beta-lactamases (ESBL) that confer resistance against commonly used antibiotics. Beta-lactamase inhibitors block these enzymes and restore the activity of beta-lactam antibiotics against initially resistant Gram-negative bacteria, therefore BL/BLI combinations are an important addition to the armamentarium for the treatment of infections caused by multidrug-resistant bacterial pathogens. Ledaborbactam etzadroxil is the orally bioavailable prodrug of ledaborbactam, a novel broad-spectrum boronic acid beta-lactamase inhibitor, which is being developed in combination with ceftibuten, an oral cephalosporin antibiotic, which is approved in the US for the treatment of upper and lower respiratory tract infections and for urinary tract infections outside the US. In vitro and in vivo studies demonstrated that ledaborbactam etzadroxil restores the activity of ceftibuten against strains of Enterobacterales expressing Ambler class A extended spectrum beta-lactamases (ESBLs), class C cephalosporinases, and class A and D carbapenemases (KPC and OXA-48, respectively) as well as multidrug-resistant (MDR) Enterobacterales. Ceftibuten-ledaborbactam etzadroxil has been granted Qualified Infectious Disease Product (QIDP) and Fast Track designations by the US Food and Drug Administration (FDA) for cUTI and uncomplicated urinary tract infections. Ceftibuten-ledaborbactam etzadroxil is an investigational drug and is not yet approved in any country for commercial use. Complicated UTIs, which include pyelonephritis (kidney infections), are defined as urinary tract infections ascending from the bladder accompanied by local and systemic signs and symptoms and are one of the most common bacterial infections in hospital and community settings. Increasing resistance of bacteria causing complicated urinary tract infections has led to limited availability of effective oral antibiotic treatment options. Currently, there are no approved oral beta-lactam or beta-lactam/beta-lactamase inhibitor combinations that are effective against Enterobacterales expressing Ambler class A ESBLs, class C cephalosporinases, and class A & D serine carbapenemases (KPC and OXA-48).공고 • Apr 27Basilea Pharmaceutica AG to Report First Half, 2026 Results on Aug 18, 2026Basilea Pharmaceutica AG announced that they will report first half, 2026 results on Aug 18, 2026공고 • Apr 17Basilea Pharmaceutica AG Approves Board and Committee AppointmentsBasilea Pharmaceutica Ltd. at its annual general meeting held on April 15, 2026, approved election of Dr. Naseem Amin and Ms. Anne Whitaker as new members of the board of directors. In addition, Mr. Kruimer, Dr. Onetto and Ms. Anne Whitaker were appointed as members of the compensation committee. The term of all board members lasts until the AGM 2027.공고 • Apr 11Basilea Pharmaceutica Ltd Announces Additional Funding for Clinical Development of Antibiotic BAL2420Basilea Pharmaceutica Ltd, Allschwil announced that it was awarded an additional USD 6 million from CARB-X (Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator), a global non-profit partnership dedicated to supporting the early development of antibacterial products. The additional non-dilutive funding will support the first-in-human phase 1 clinical study of Basilea’s novel antibiotic BAL2420 (LptA inhibitor) and related activities. The phase 1 study has already been initiated, with the first subject dosed in March 2026. BAL2420 belongs to one of the very few novel classes of antibiotics in clinical development. It is targeting LptA, which is part of the lipopolysaccharide transport bridge, an essential structure in Gram-negative bacteria. LptA inhibitors have shown potent and rapid bactericidal activity in vitro and in vivo against Gram-negative bacteria of the Enterobacteriaceae family, such as E. coli and K. pneumoniae, including strains resistant to beta-lactams and colistin, an antibiotic regarded as last-resort therapy. The Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO) have identified Enterobacteriaceae, including carbapenem-resistant strains, as high priority pathogens for which new and effective antibiotic treatments are urgently needed. CARB-X has supported the development of BAL2420 since 2020, advancing the project from the hit-to-lead stage to the first-in-human study. Research reported in this publication is supported by CARB-X. CARB-X is funded in part with federal funds from the U.S. Department of Health and Human Services (HHS); Administration for Strategic Preparedness and Response; Biomedical Advanced Research and Development Authority (BARDA) under agreement number 75A50122C00028 and by awards from Wellcome (WT224842), the UK Department of Health and Social Care’s Global Antimicrobial Resistance Innovation Fund (GAMRIF), the Gates Foundation, Germany’s Federal Ministry of Research, Technology and Space (BMFTR), the Novo Nordisk Foundation, Italy’s Ministry of Economy and Finance (MEF), Japan’s Ministry of Health, the European Commission’s DG Health Emergency Preparedness and Response Authority (DG HERA), and KfW Development Bank. The U.S. National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH) in HHS, provides support in the form of in-kind services through access to a suite of preclinical services for product development. The content of this publication is solely the responsibility of the authors and does not necessarily represent the official views of CARB-X or its funders.공고 • Mar 26Basilea Pharmaceutica AG, Annual General Meeting, Apr 15, 2026Basilea Pharmaceutica AG, Annual General Meeting, Apr 15, 2026, at 14:00 W. Europe Standard Time.공고 • Mar 23Basilea Pharmaceutica Ltd Announces Start Of First-In-Human Study Of Novel Antibiotic BAL2420Basilea Pharmaceutica Ltd, Allschwil (SIX: BSLN), a commercial-stage biopharmaceutical company committed to meeting the needs of patients with severe bacterial and fungal infections, announced the dosing of the first healthy volunteer in the first-in-human phase 1 study of BAL2420, evaluating the safety, tolerability and pharmacokinetics of this lipopolysaccharide transport protein A (LptA) inhibitor. BAL2420 belongs to a novel class of antibiotics. It targets LptA, which is part of the lipopolysaccharide transport bridge, an essential structure in Gram-negative bacteria. LptA inhibitors have shown potent and rapid bactericidal activity in vitro and in vivo against Gram-negative bacteria of the Enterobacteriaceae family, such as E. coli and K. pneumoniae, including strains resistant to beta-lactams and colistin, an antibiotic regarded as last-resort therapy. The Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO) have identified Enterobacteriaceae, including carbapenem-resistant strains, as high priority pathogens for which new and effective antibiotic treatments are urgently needed. This single-center, randomized, dose-escalation, double-blind and placebo-controlled phase 1 study assesses intravenous administration of BAL2420 using a single- and multiple-ascending dose study design. Data from this study will support the further clinical development of BAL2420 as a potential treatment option for serious infections caused by Gram-negative bacteria, including multidrug-resistant bacteria. CARB-X has supported the development of BAL2420 since 2020, advancing the project from the Hit-to-Lead stage to the first-in-human study. CARB-X’s funding for this project is provided by federal funds from the US Department of Health and Human Services; Administration for Strategic Preparedness and Response; Biomedical Advanced Research and Development Authority; under agreement number: 75A50122C00028, and by awards from Wellcome (WT224842) and Germany’s Federal Ministry of Research, Technology and Space (BMFTR). The content of this press release is solely the responsibility of the authors and does not necessarily represent the official views of CARB-X or any of its funders.공고 • Feb 18+ 1 more updateBasilea Pharmaceutica AG Provides Earnings Guidance for the Full Year 2026Basilea Pharmaceutica AG provided earnings guidance for the full year 2026. For the year, the company expects total revenue of ~10% increase. Operating profit of ~20% increase.이익 및 매출 성장 예측DB:PK5 - 애널리스트 향후 추정치 및 과거 재무 데이터 (CHF Millions)날짜매출이익자유현금흐름영업현금흐름평균 애널리스트 수12/31/202820219N/A20212/31/202727144N/A12412/31/202626154N/A59412/31/2025232405962N/A9/30/2025234566971N/A6/30/2025236737879N/A3/31/2025222757577N/A12/31/2024209787374N/A9/30/2024179384142N/A6/30/2024149-1910N/A3/31/202415351112N/A12/31/2023158101314N/A9/30/2023166332022N/A6/30/2023175562729N/A3/31/2023161341618N/A12/31/20221481247N/A9/30/20221506-21N/A6/30/20221521-8-5N/A3/31/2022150-3-20-18N/A12/31/2021148-7-33-32N/A9/30/2021130-26-41-40N/A6/30/2021112-45-50-48N/A3/31/2021120-30-53-51N/A12/31/2020128-15-56-54N/A9/30/2020134-6-55-53N/A6/30/20201413-53-52N/A3/31/2020137-10-58-58N/A12/31/2019134-22-64-64N/A9/30/2019135-23N/A-64N/A6/30/2019136-24N/A-64N/A3/31/2019134-28N/A-72N/A12/31/2018133-31N/A-79N/A9/30/2018124-26N/A-42N/A6/30/2018115-21N/A-5N/A3/31/2018108-20N/A7N/A12/31/2017102-19N/A19N/A9/30/201792-32N/A-19N/A6/30/201782-44N/A-58N/A3/31/201774-48N/A-66N/A12/31/201666-51N/A-75N/A9/30/201662-55N/A-89N/A6/30/201658-59N/A-102N/A3/31/201655-61N/A-85N/A12/31/201553-62N/A-68N/A9/30/201550-57N/A-57N/A더 보기애널리스트 향후 성장 전망수입 대 저축률: PK5 의 연간 예상 수익 증가율(4.9%)이 saving rate(2.1%)보다 높습니다.수익 vs 시장: PK5 의 연간 수익(4.9%)이 German 시장(15.3%)보다 느리게 성장할 것으로 예상됩니다.고성장 수익: PK5 의 수입은 증가할 것으로 예상되지만 상당히 증가하지는 않을 것입니다.수익 대 시장: PK5 의 수익은 향후 3년간 감소할 것으로 예상됩니다(연간 -1.8%).고성장 매출: PK5 의 수익은 향후 3년 동안 감소할 것으로 예상됩니다(연간 -1.8%).주당순이익 성장 예측향후 자기자본이익률미래 ROE: PK5의 자본 수익률은 3년 후 11.2%로 낮을 것으로 예상됩니다.성장 기업 찾아보기7D1Y7D1Y7D1YPharmaceuticals-biotech 산업의 고성장 기업.View Past Performance기업 분석 및 재무 데이터 상태데이터최종 업데이트 (UTC 시간)기업 분석2026/08/16 02:00종가2026/08/14 00:00수익2025/12/31연간 수익2025/12/31데이터 소스당사의 기업 분석에 사용되는 데이터는 S&P Global Market Intelligence LLC에서 제공됩니다. 아래 데이터는 이 보고서를 생성하기 위해 분석 모델에서 사용됩니다. 데이터는 정규화되므로 소스가 제공된 후 지연이 발생할 수 있습니다.패키지데이터기간미국 소스 예시 *기업 재무제표10년손익계산서현금흐름표대차대조표SEC 양식 10-KSEC 양식 10-Q분석가 컨센서스 추정치+3년재무 예측분석가 목표주가분석가 리서치 보고서Blue Matrix시장 가격30년주가배당, 분할 및 기타 조치ICE 시장 데이터SEC 양식 S-1지분 구조10년주요 주주내부자 거래SEC 양식 4SEC 양식 13D경영진10년리더십 팀이사회SEC 양식 10-KSEC 양식 DEF 14A주요 개발10년회사 공시SEC 양식 8-K* 미국 증권에 대한 예시이며, 비(非)미국 증권에는 해당 국가의 규제 서식 및 자료원을 사용합니다.별도로 명시되지 않는 한 모든 재무 데이터는 연간 기간을 기준으로 하지만 분기별로 업데이트됩니다. 이를 TTM(최근 12개월) 또는 LTM(지난 12개월) 데이터라고 합니다. 자세히 알아보기.분석 모델 및 스노우플레이크이 보고서를 생성하는 데 사용된 분석 모델의 세부 정보는 당사의 GitHub 페이지에서 확인하실 수 있습니다. 또한 보고서 사용 방법에 대한 가이드와 YouTube 튜토리얼도 제공하고 있습니다.Simply Wall St 분석 모델을 설계하고 구축한 세계적 수준의 팀에 대해 알아보세요.산업 및 섹터 지표산업 및 섹터 지표는 Simply Wall St가 6시간마다 계산하며, 프로세스에 대한 자세한 내용은 Github에서 확인할 수 있습니다.분석가 소스Basilea Pharmaceutica AG는 17명의 분석가가 다루고 있습니다. 이 중 4명의 분석가가 우리 보고서에 입력 데이터로 사용되는 매출 또는 수익 추정치를 제출했습니다. 분석가의 제출 자료는 하루 종일 업데이트됩니다.분석가기관Brigitte de LimaBofA Global ResearchBrian WhiteCalvine Partners LLPAndrew KeithCalvine Partners LLP14명의 분석가 더 보기
공고 • Feb 18+ 1 more updateBasilea Pharmaceutica AG Provides Earnings Guidance for the Full Year 2026Basilea Pharmaceutica AG provided earnings guidance for the full year 2026. For the year, the company expects total revenue of ~10% increase. Operating profit of ~20% increase.
공고 • Aug 06Basilea Pharmaceutica Ltd Receives Additional Funding to Continue Development of Novel Antibiotic Ceftibuten-Ledaborbactam EtzadroxilBasilea Pharmaceutica Ltd. has been awarded an additional USD 5.4 million of funding by the Biomedical Advanced Research and Development Authority (BARDA), part of the Administration for Strategic Preparedness and Response (ASPR) within the U.S. Department of Health and Human Services, to continue the development of the novel oral antibiotic ceftibuten-ledaborbactam etzadroxil, a beta-lactam/beta-lactamase inhibitor (BL/BLI) combination, for the treatment of complicated urinary tract infections (cUTIs), including pyelonephritis. After this additional funding of USD 5.4 million, a total of USD 30.8 million of funding has been awarded to Basilea by BARDA. The contract has the potential to provide a total of up to USD 172 million of non-dilutive funding, of which approximately USD 14 million relate to the period prior to novation of the contract to Basilea. Many Gram-negative bacteria express enzymes such as extended spectrum beta-lactamases (ESBL) that confer resistance against commonly used antibiotics. Beta-lactamase inhibitors block these enzymes and restore the activity of beta-lactam antibiotics against initially resistant Gram-negative bacteria, therefore BL/BLI combinations are an important addition to the armamentarium for the treatment of infections caused by multidrug-resistant bacterial pathogens. Ledaborbactam etzadroxil is the orally bioavailable prodrug of ledaborbactam, a novel broad-spectrum boronic acid beta-lactamase inhibitor, which is being developed in combination with ceftibuten, an oral cephalosporin antibiotic, which is approved in the US for the treatment of upper and lower respiratory tract infections and for urinary tract infections outside the US. In vitro and in vivo studies demonstrated that ledaborbactam etzadroxil restores the activity of ceftibuten against strains of Enterobacterales expressing Ambler class A extended spectrum beta-lactamases (ESBLs), class C cephalosporinases, and class A and D carbapenemases (KPC and OXA-48, respectively) as well as multidrug-resistant (MDR) Enterobacterales. Ceftibuten-ledaborbactam etzadroxil has been granted Qualified Infectious Disease Product (QIDP) and Fast Track designations by the US Food and Drug Administration (FDA) for cUTI and uncomplicated urinary tract infections. Ceftibuten-ledaborbactam etzadroxil is an investigational drug and is not yet approved in any country for commercial use. Complicated UTIs, which include pyelonephritis (kidney infections), are defined as urinary tract infections ascending from the bladder accompanied by local and systemic signs and symptoms and are one of the most common bacterial infections in hospital and community settings. Increasing resistance of bacteria causing complicated urinary tract infections has led to limited availability of effective oral antibiotic treatment options. Currently, there are no approved oral beta-lactam or beta-lactam/beta-lactamase inhibitor combinations that are effective against Enterobacterales expressing Ambler class A ESBLs, class C cephalosporinases, and class A & D serine carbapenemases (KPC and OXA-48).
공고 • Jul 29Basilea Receives USD 30 Million Funding Under Existing BARDA Agreement for Advancing Phase 3 Development of Novel Antifungal FosmanogepixBasilea Pharmaceutica Ltd, Allschwil announced that the Biomedical Advanced Research and Development Authority (BARDA), part of the Administration for Strategic Preparedness and Response (ASPR) within the U.S. Department of Health and Human Services (HHS), awarded USD 30 million in additional funding to Basilea after meeting its prespecified enrollment milestone. The additional funding will continue to advance Basilea’s ongoing phase 3 program for the novel antifungal, fosmanogepix. The commitment is made under the “Other Transaction Agreement” (OTA, agreement number 75A50124C00033). The new tranche of USD 30 million comes in addition to the USD 93 million already committed by BARDA since the signing of the OTA in September 2024. BARDA’s financial contribution is about 60% of the total costs of the supported projects, fosmanogepix and BAL2062, including clinical and regulatory activities, over the term of the OTA, which could provide a total potential non-dilutive funding of up to approximately USD 268 million over up to 12 years, if all additional options to extend the contract are exercised by BARDA. Fosmanogepix is a first-in-class clinical-stage broad-spectrum antifungal. It has a novel mechanism of action and its active moiety has shown activity against common species of Candida and Aspergillus, including multi-drug-resistant strains, such as Candida auris and Candida glabrata, as well as rare difficult-to-treat molds including Fusarium spp., Scedosporium spp., and some fungi from the Mucorales order. Fosmanogepix intravenous and oral formulations have been evaluated in clinical phase 2 studies for the treatment of patients with Candidemia, including Candida auris infections, and invasive mold infections. The FAST study, a phase 3 study evaluating fosmanogepix in the treatment of adult patients with candidemia and/or invasive candidiasis and the FORWARD study, a phase 3 study, in the treatment of adult patients with invasive mold infections, are ongoing. Fosmanogepix has received Fast Track and Orphan Drug designations from the U.S. Food and Drug Administration for a number of indications, and is designated as a Qualified Infectious Disease Product (QIDP). BAL2062 is a first-in-class clinical-stage antifungal, derived from a natural product, and has demonstrated fungicidal activity against clinically important molds such as Aspergillus spp., including azole-resistant strains. Safety and tolerability have been demonstrated in a previously completed phase 1 study with single and multiple ascending intravenous (i.v.) doses. The drug candidate has Qualified Infectious Disease Product (QIDP), Orphan Drug and Fast Track designation from the US Food and Drug Administration (FDA) for invasive aspergillosis.
공고 • May 28Basilea Pharmaceutica Ltd Receives Additional USD 13.3 Million From BARDA To Continue Development Of Novel Antibiotic Ceftibuten-Ledaborbactam EtzadroxilBasilea Pharmaceutica Ltd, Allschwil announced that the Biomedical Advanced Research and Development Authority (BARDA), part of the Administration for Strategic Preparedness and Response (ASPR) within the U.S. Department of Health and Human Services, awarded USD 13.3 million to Basilea to continue the development of Basilea’s novel oral antibiotic ceftibuten-ledaborbactam etzadroxil, a beta-lactam/beta-lactamase inhibitor (BL/BLI) combination, for the treatment of complicated urinary tract infections (cUTIs), including pyelonephritis. After the current tranche of USD 13.3 million, a total of USD 25 million have been committed by BARDA. The contract could provide up to USD 133 million of additional non-dilutive funding. Many Gram-negative bacteria express enzymes such as extended spectrum beta-lactamases (ESBL) that confer resistance against commonly used antibiotics. Beta-lactamase inhibitors block these enzymes and restore the activity of beta-lactam antibiotics against initially resistant Gram-negative bacteria, therefore BL/BLI combinations are an important addition to the armamentarium for the treatment of infections caused by multidrug-resistant bacterial pathogens. Ledaborbactam etzadroxil is the orally bioavailable prodrug of ledaborbactam, a novel broad-spectrum boronic acid beta-lactamase inhibitor, which is being developed in combination with ceftibuten, an oral cephalosporin antibiotic, which is approved in the US for the treatment of upper and lower respiratory tract infections and for urinary tract infections outside the US. In vitro and in vivo studies demonstrated that ledaborbactam etzadroxil restores the activity of ceftibuten against strains of Enterobacterales expressing Ambler class A extended spectrum beta-lactamases (ESBLs), class C cephalosporinases, and class A and D carbapenemases (KPC and OXA-48, respectively) as well as multidrug-resistant (MDR) Enterobacterales. Ceftibuten-ledaborbactam etzadroxil has been granted Qualified Infectious Disease Product (QIDP) and Fast Track designations by the US Food and Drug Administration (FDA) for cUTI and uncomplicated urinary tract infections. Ceftibuten-ledaborbactam etzadroxil is an investigational drug and is not yet approved in any country for commercial use. Complicated UTIs, which include pyelonephritis (kidney infections), are defined as urinary tract infections ascending from the bladder accompanied by local and systemic signs and symptoms and are one of the most common bacterial infections in hospital and community settings. Increasing resistance of bacteria causing complicated urinary tract infections has led to limited availability of effective oral antibiotic treatment options. Currently, there are no approved oral beta-lactam or beta-lactam/beta-lactamase inhibitor combinations that are effective against Enterobacterales expressing Ambler class A ESBLs, class C cephalosporinases, and class A & D serine carbapenemases (KPC and OXA-48).
공고 • Apr 27Basilea Pharmaceutica AG to Report First Half, 2026 Results on Aug 18, 2026Basilea Pharmaceutica AG announced that they will report first half, 2026 results on Aug 18, 2026
공고 • Apr 17Basilea Pharmaceutica AG Approves Board and Committee AppointmentsBasilea Pharmaceutica Ltd. at its annual general meeting held on April 15, 2026, approved election of Dr. Naseem Amin and Ms. Anne Whitaker as new members of the board of directors. In addition, Mr. Kruimer, Dr. Onetto and Ms. Anne Whitaker were appointed as members of the compensation committee. The term of all board members lasts until the AGM 2027.
공고 • Apr 11Basilea Pharmaceutica Ltd Announces Additional Funding for Clinical Development of Antibiotic BAL2420Basilea Pharmaceutica Ltd, Allschwil announced that it was awarded an additional USD 6 million from CARB-X (Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator), a global non-profit partnership dedicated to supporting the early development of antibacterial products. The additional non-dilutive funding will support the first-in-human phase 1 clinical study of Basilea’s novel antibiotic BAL2420 (LptA inhibitor) and related activities. The phase 1 study has already been initiated, with the first subject dosed in March 2026. BAL2420 belongs to one of the very few novel classes of antibiotics in clinical development. It is targeting LptA, which is part of the lipopolysaccharide transport bridge, an essential structure in Gram-negative bacteria. LptA inhibitors have shown potent and rapid bactericidal activity in vitro and in vivo against Gram-negative bacteria of the Enterobacteriaceae family, such as E. coli and K. pneumoniae, including strains resistant to beta-lactams and colistin, an antibiotic regarded as last-resort therapy. The Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO) have identified Enterobacteriaceae, including carbapenem-resistant strains, as high priority pathogens for which new and effective antibiotic treatments are urgently needed. CARB-X has supported the development of BAL2420 since 2020, advancing the project from the hit-to-lead stage to the first-in-human study. Research reported in this publication is supported by CARB-X. CARB-X is funded in part with federal funds from the U.S. Department of Health and Human Services (HHS); Administration for Strategic Preparedness and Response; Biomedical Advanced Research and Development Authority (BARDA) under agreement number 75A50122C00028 and by awards from Wellcome (WT224842), the UK Department of Health and Social Care’s Global Antimicrobial Resistance Innovation Fund (GAMRIF), the Gates Foundation, Germany’s Federal Ministry of Research, Technology and Space (BMFTR), the Novo Nordisk Foundation, Italy’s Ministry of Economy and Finance (MEF), Japan’s Ministry of Health, the European Commission’s DG Health Emergency Preparedness and Response Authority (DG HERA), and KfW Development Bank. The U.S. National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH) in HHS, provides support in the form of in-kind services through access to a suite of preclinical services for product development. The content of this publication is solely the responsibility of the authors and does not necessarily represent the official views of CARB-X or its funders.
공고 • Mar 26Basilea Pharmaceutica AG, Annual General Meeting, Apr 15, 2026Basilea Pharmaceutica AG, Annual General Meeting, Apr 15, 2026, at 14:00 W. Europe Standard Time.
공고 • Mar 23Basilea Pharmaceutica Ltd Announces Start Of First-In-Human Study Of Novel Antibiotic BAL2420Basilea Pharmaceutica Ltd, Allschwil (SIX: BSLN), a commercial-stage biopharmaceutical company committed to meeting the needs of patients with severe bacterial and fungal infections, announced the dosing of the first healthy volunteer in the first-in-human phase 1 study of BAL2420, evaluating the safety, tolerability and pharmacokinetics of this lipopolysaccharide transport protein A (LptA) inhibitor. BAL2420 belongs to a novel class of antibiotics. It targets LptA, which is part of the lipopolysaccharide transport bridge, an essential structure in Gram-negative bacteria. LptA inhibitors have shown potent and rapid bactericidal activity in vitro and in vivo against Gram-negative bacteria of the Enterobacteriaceae family, such as E. coli and K. pneumoniae, including strains resistant to beta-lactams and colistin, an antibiotic regarded as last-resort therapy. The Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO) have identified Enterobacteriaceae, including carbapenem-resistant strains, as high priority pathogens for which new and effective antibiotic treatments are urgently needed. This single-center, randomized, dose-escalation, double-blind and placebo-controlled phase 1 study assesses intravenous administration of BAL2420 using a single- and multiple-ascending dose study design. Data from this study will support the further clinical development of BAL2420 as a potential treatment option for serious infections caused by Gram-negative bacteria, including multidrug-resistant bacteria. CARB-X has supported the development of BAL2420 since 2020, advancing the project from the Hit-to-Lead stage to the first-in-human study. CARB-X’s funding for this project is provided by federal funds from the US Department of Health and Human Services; Administration for Strategic Preparedness and Response; Biomedical Advanced Research and Development Authority; under agreement number: 75A50122C00028, and by awards from Wellcome (WT224842) and Germany’s Federal Ministry of Research, Technology and Space (BMFTR). The content of this press release is solely the responsibility of the authors and does not necessarily represent the official views of CARB-X or any of its funders.
공고 • Feb 18+ 1 more updateBasilea Pharmaceutica AG Provides Earnings Guidance for the Full Year 2026Basilea Pharmaceutica AG provided earnings guidance for the full year 2026. For the year, the company expects total revenue of ~10% increase. Operating profit of ~20% increase.