Recent Insider Transactions Derivative • May 05
Founder notifies of intention to sell stock Christopher Kroeger intends to sell 236k shares in the next 90 days after lodging an Intent To Sell Form on the 4th of May. If the sale is conducted around the recent share price of US$30.70, it would amount to US$7.3m. For the year to December 2023, Christopher's total compensation was 3% salary and 97% other compensation. This indicates that these sales could comprise a meaningful part of their income for the year. Since September 2025, Christopher's direct individual holding has increased from 6.02k shares to 325.10k. Company insiders have collectively sold US$674k more than they bought, via options and on-market transactions in the last 12 months. お知らせ • May 04
MapLight Therapeutics Announces Completion of Enrollment In Zephyr Phase 2 Trial And Updates Expected Timing of Topline Results MapLight Therapeutics, Inc. announced completion of enrollment in its Phase 2 ZEPHYR trial evaluating ML-007C-MA for the treatment of schizophrenia. The Company also announced completion of the final patient visit in its Phase 2 IRIS trial evaluating ML-004 for the treatment of autism spectrum disorder. The Company expects to report topline results from both Phase 2 trials by mid-August 2026. The Phase 2 ZEPHYR trial is a randomized, double-blind, placebo-controlled trial evaluating the efficacy, safety, and tolerability of ML-007C-MA in inpatient adult participants with schizophrenia experiencing an acute exacerbation of psychosis. 307 participants in the trial were randomized 1:1:1 to receive either placebo, ML-007C-MA 210/3 mg twice daily, or ML-007C-MA 330/6 mg once daily. Primary endpoint is the change in PANSS total score from baseline to Week 5. Key secondary endpoints include change in CGI-S score, PANSS-Marder positive and negative factor scores from baseline to Week 5. Exploratory endpoints include change in cognitive function, assessed across multiple domains commonly impacted in schizophrenia, from baseline to Week 5. The Phase 2 IRIS trial is a randomized, double-blind, placebo-controlled trial evaluating the efficacy, safety, and tolerability of ML-004 in adults and adolescents with autism spectrum disorder. 161 participants were randomized in the trial, consistent with enrollment target of over 100 adolescents (aged 12-17). Primary endpoint is the change in Autism Behavioral Inventory (ABI)-Social Communication Domain Score from baseline to Week 12. Key secondary endpoints include change in CGI-I, ABI-C and Aberrant Behavior Checklist-Irritability (ABC-I) score from baseline to Week 12. お知らせ • May 01
MapLight Therapeutics, Inc., Annual General Meeting, Jun 23, 2026 MapLight Therapeutics, Inc., Annual General Meeting, Jun 23, 2026. Recent Insider Transactions Derivative • Apr 16
Founder notifies of intention to sell stock Christopher Kroeger intends to sell 21k shares in the next 90 days after lodging an Intent To Sell Form on the 15th of April. If the sale is conducted around the recent share price of US$27.02, it would amount to US$563k. For the year to December 2023, Christopher's total compensation was 7% salary and 93% other compensation. This indicates that these sales could comprise a meaningful part of their income for the year. Since September 2025, Christopher's direct individual holding has increased from 6.02k shares to 148.86k. Company insiders have collectively sold US$674k more than they bought, via options and on-market transactions in the last 12 months. New Risk • Apr 10
New minor risk - Share price stability The company's share price has been volatile over the past 3 months. It is more volatile than 75% of American stocks, typically moving 11% a week. This is considered a minor risk. Share price volatility indicates the stock is highly sensitive to market conditions or economic conditions rather than being sensitive to its own business performance, which may also be inconsistent. It also increases the risk of potential losses in the short term as the stock tends to have larger drops in price more frequently than other stocks. Currently, the following risks have been identified for the company: Major Risks Earnings are forecast to decline by an average of 11% per year for the foreseeable future. Revenue is less than US$1m. Minor Risks Currently unprofitable and not forecast to become profitable over next 3 years (US$286m net loss in 3 years). Share price has been volatile over the past 3 months (11% average weekly change). Significant insider selling over the past 3 months (US$1.4m sold). Recent Insider Transactions • Mar 03
Co-Founder recently sold US$260k worth of stock On the 24th of February, Robert Malenka sold around 14k shares on-market at roughly US$18.34 per share. This transaction amounted to 9.1% of their direct individual holding at the time of the trade. In the last 3 months, they made an even bigger sale worth US$636k. Robert has been a net seller over the last 12 months, reducing personal holdings by US$1.4m. Recent Insider Transactions Derivative • Feb 24
Co-Founder notifies of intention to sell stock Robert Malenka intends to sell 11k shares in the next 90 days after lodging an Intent To Sell Form on the 23rd of February. If the sale is conducted around the recent share price of US$18.42, it would amount to US$207k. Since September 2025, Robert's direct individual holding has increased from 3.38k shares to 155.74k. Company insiders have collectively sold US$414k more than they bought, via options and on-market transactions in the last 12 months. Recent Insider Transactions • Feb 13
Independent Director recently bought US$253k worth of stock On the 10th of February, Timothy Garnett bought around 14k shares on-market at roughly US$17.89 per share. This transaction amounted to 29% of their direct individual holding at the time of the trade. This was the largest purchase by an insider in the last 3 months. Insiders have collectively bought US$16m more in shares than they have sold in the last 12 months. Recent Insider Transactions Derivative • Feb 12
Co-Founder notifies of intention to sell stock Robert Malenka intends to sell 7k shares in the next 90 days after lodging an Intent To Sell Form on the 10th of February. If the sale is conducted around the recent share price of US$18.12, it would amount to US$120k. Since September 2025, Robert's direct individual holding has increased from 3.38k shares to 174.72k. Company insiders have collectively bought US$15m more than they sold, via options and on-market transactions, in the last 12 months. Recent Insider Transactions • Feb 01
Co-Founder recently sold US$636k worth of stock On the 30th of January, Robert Malenka sold around 34k shares on-market at roughly US$18.49 per share. This transaction amounted to 16% of their direct individual holding at the time of the trade. This was the largest sale by an insider in the last 3 months. This was Robert's only on-market trade for the last 12 months. Recent Insider Transactions Derivative • Jan 29
Co-Founder notifies of intention to sell stock Robert Malenka intends to sell 7k shares in the next 90 days after lodging an Intent To Sell Form on the 28th of January. If the sale is conducted around the recent share price of US$18.65, it would amount to US$122k. Since September 2025, Robert's direct individual holding has increased from 3.38k shares to 31.67k. There has only been one transaction (US$16m purchase) from insiders over the last 12 months. お知らせ • Jan 09
MapLight Therapeutics, Inc. Updates Expected Timing of Topline Results for Ongoing Phase 2 Studies to Third Quarter of 2026 MapLight Therapeutics, Inc. announced an update to the expected timing of topline results for its ongoing Phase 2 ZEPHYR and IRIS clinical studies, which are progressing ahead of schedule. The company's Phase 2 ZEPHYR trial evaluating ML-007C-MA for the treatment of schizophrenia continues to enroll robust, and topline results are now expected in the third quarter of 2026. The ZEPHYR study is a randomized, double-blind, placebo-controlled trial that is expected to enroll 300 hospitalized adult participants with schizophrenia experiencing acute exacerbation of psychosis. In addition, following completion of enrollment in the Phase 2 IRIS trial for ML-004 in autism spectrum disorder, topline results for that study are now expected in the third quarter of 2026. The IRIS study is a double-blind, placebo-controlled trial that randomized approximately 160 adult and adolescent participants. お知らせ • Jan 05
Maplight Therapeutics, Inc. Receives Fast Track Designation for ML-007C-Ma for Alzheimer's Disease Psychosis MapLight Therapeutics, Inc. announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation to ML-007C-MA, an investigational novel M1/M4 muscarinic agonist, for the treatment of hallucinations and delusions associated with Alzheimer's disease psychosis (ADP). The Fast Track process is intended to facilitate the development and expedite the review of investigational therapies for serious conditions with unmet medical need. A drug with Fast Track designation may be eligible for more frequent interactions with the FDA, as well as accelerated approval and priority review, if applicable criteria are met. In a Phase 1 clinical trial, ML-007C-MA demonstrated a generally favorable safety and tolerability profile with twice daily dosing in healthy elderly participants. Enrollment is currently ongoing in the Phase 2 VISTA study, a randomized, double-blind, placebo-controlled trial evaluating ML-007C-MA for the treatment of hallucinations and delays associated with ADP. MapLight expects to enroll 300 participants in the trial and report topline results in the second half of 2027. Recent Insider Transactions • Nov 02
Independent Director recently bought US$16m worth of stock On the 28th of October, Jim Trenkle bought around 953k shares on-market at roughly US$17.00 per share. This transaction amounted to 35% of their direct individual holding at the time of the trade. This was the largest purchase by an insider in the last 3 months. This was the only on-market transaction from insiders over the last 12 months. Board Change • Oct 28
High number of new and inexperienced directors There are 6 new directors who have joined the board in the last 3 years. The company's board is composed of: 6 new directors. 6 experienced directors. No highly experienced directors. Founder, President, CEO & Director Chris Kroeger is the most experienced director on the board, commencing their role in 2018. The following issues are considered to be risks according to the Simply Wall St Risk Model: Lack of board continuity. Lack of experienced directors. お知らせ • Oct 27
MapLight Therapeutics, Inc. has completed an IPO in the amount of $250.75 million. MapLight Therapeutics, Inc. has completed an IPO in the amount of $250.75 million.
Security Name: Common Stock
Security Type: Common Stock
Securities Offered: 14,750,000
Price\Range: $17
Discount Per Security: $1.19
Transaction Features: Reserved Share Offering; Sponsor Backed Offering